Confused with new results.: After following the... - Thyroid UK

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Confused with new results.

BlueDaisy22 profile image
11 Replies

After following the helpful info from Jaydee1507 @helvella SlowDragon last time, I have added some background to my profile.

Also 2 newest symptoms pink scaly rash right cheek and puffy under left eye, also increasingly noticeable brain fog. I do not feel great.

I have just had my results, posted below with units and ranges, which I thought would show AITD / hashimotos as I thought it would explain all my weird symptoms over the last couple of years. But nonplussed to find

Anti thyroid peroxidase 0.7 IU/ml

Negative.

However my TSH is lower from 6.2 in Oct to 5.5 (0.35-4.94).

T4 lower from 12.4 in Oct to 9.7 (9.01-19.05).

Could someone help me understand what my results mean please ? Do the low numbers mean I am hypothyroid?

I have supplemented nature provides B12 drops which explain big jump in B12 to 845 pg/ml (187 -883).

Jarrow B complex (stopped6 days before fasted blood test) folate increased from 3.9 to 12.1.

Better you D3K2 spray and then nature provides D3K2 in black seed oil since 4th Jan (better you tasted very sweet so changed. Also read o.n here,that black seed oil can help in conversion t4 to t3) so vit D up from 43.7 to 79.2.

Your lovely helpful advice has helped all these.

Have tried eating more iron rich foods and got a bit of change in serum ferritin 47 up to 53 ng/mL (20-204).

Bit concerned with my iron studies though

Serum iron level 14.8 umol/L (4.4-27.9)

Serum transferrin 2 g/L (2-3.2)

Transferrin sat index 29% (0-55%)

Do these mean I should take iron supplement?

I have appointment to see GP next week and would be very grateful for any advice you may have.

Thank you for reading :-).

TSH 5.55 mIU/L (0.35 - 4.94) 113.3%Free T4 (fT4) 9.7 pmol/L (9.01 - 19.05) 6.9%

Free T3 (fT3) 3.4 pmol/L (2.63 - 5.70) 25.1%

T4:T3 Ratio 2.853 

Thyroid Peroxidase Antibodies (TPO) 0.7 IU/mL

Folate - Serum 12.1 ug/L (3.1 - 20.50) 51.7%

Vitamin B12 845 nmol/L (187 - 883) 94.5%

Vitamin D 79.2 nmol/L (50.00 - 150.00) 29.2%

Ferritin 53 ug/L (20.00 - 204.00) 17.9%

Mean corpuscular volume 89.1 fl (80.00 - 100.00) 45.5%

Mean corpuscular haemoglobin 31.8 pg (27.00 - 32.00) 96.0%

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BlueDaisy22
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SlowDragon profile image
SlowDragonAdministrator

18.10.24 Test results below.

TSH 6.2 mIU/L (0.35 - 4.94) 127.5%

Free T4 (fT4) 12.4 pmol/L (9.01 - 19.05) 33.8%

Jan 2025 test results

TSH 5.55 mIU/L (0.35 - 4.94) 113.3%

Free T4 (fT4) 9.7 pmol/L (9.01 - 19.05) 6.9%

Free T3 (fT3) 3.4 pmol/L (2.63 - 5.70) 25.1%

Were both tests by NHS

And were both tests early morning

With two NHS test results with TSH over 5, and symptoms and falling Ft4 result you could be offered 3-6 months trial on Levothyroxine

Starting levothyroxine - flow chart

gps.northcentrallondonccg.n...

Or you might continue improving vitamin levels and retest again in another 2-3 months

Your choice

Standard STARTER dose levothyroxine is 50mcg

Keep working on improving vitamin D …..are you also taking a separate magnesium supplement

Ferritin is going up…..keep going

Will tag FallingInReverse and humanbean to comment on iron/ferritin

You can reduce and stop B12 drops

Just continue with vitamin B complex

Antibodies

About 90% of primary hypothyroidism is autoimmune thyroid disease, usually diagnosed by high TPO and/or high TG thyroid antibodies

Autoimmune thyroid disease with goitre is Hashimoto’s

Autoimmune thyroid disease without goitre is Ord’s thyroiditis.

Both are autoimmune and generally called Hashimoto’s.

Significant minority of Hashimoto’s patients only have high TG antibodies (thyroglobulin)

NHS only tests TG antibodies if TPO are high

20% of autoimmune thyroid patients never have high thyroid antibodies and ultrasound scan of thyroid can get diagnosis

Recommended that all thyroid blood tests early morning, ideally just before 9am, only drink water between waking and test

This gives highest TSH, lowest FT4 and most consistent results. (Patient to patient tip)

Private tests are available as NHS currently rarely tests Ft3 or all relevant vitamins

Post all about what time of day to test

healthunlocked.com/thyroidu...

Testing options and includes money off codes for private testing

thyroiduk.org/testing/

Medichecks Thyroid plus BOTH TPO and TG antibodies and vitamins

medichecks.com/products/adv...

Blue Horizon Thyroid Premium Gold includes BOTH TPO and TG antibodies, cortisol and vitamins

bluehorizonbloodtests.co.uk...

Medichecks and BH also offer private blood draw at clinic near you, or private nurse to your own home…..for an extra fee

Randox FULL thyroid test including both thyroid antibodies just £31

Test at home or in clinic

Also available via Amazon

randoxhealth.com/en-GB/at-h...

Only do private testing early Monday or Tuesday morning.

Tips on how to do DIY finger prick test

support.medichecks.com/hc/e...

BlueDaisy22 profile image
BlueDaisy22 in reply toSlowDragon

Yes both blood tests NHS. October one about 9.30am and Jan 25 one 8.50am.Should I ask the GP to do the other antibody test ? Might I be auto immune after all?

BlueDaisy22 profile image
BlueDaisy22 in reply toBlueDaisy22

Sorry forgot to say I am taking some magnesium doing Epsom salt baths putting on some mag gel but hard to know what dose I'm getting and swallowing bits chipped off a mag bisglycinate tab 100mg ( made a bit of a boob buying giant sized tabs I can't swallow!!!) And thank you for answering me so quickly.

SlowDragon profile image
SlowDragonAdministrator in reply toBlueDaisy22

magnesium

Chop them up with sharp knife into small bits and chew up with some water to wash them down

SlowDragon profile image
SlowDragonAdministrator in reply toBlueDaisy22

Should I ask the GP to do the other antibody test ?

NHS won’t test Thyroglobulin antibodies as your TPO antibodies are negative

You will have to test privately

Randox is cheapest

But if want to wait and test in 2-3 months and include vitamin testing again …..then look at Medichecks or BH

if both antibodies negative, look at getting ultrasound scan of thyroid via GP or privately - approx £100

BlueDaisy22 profile image
BlueDaisy22 in reply toSlowDragon

OK, will have a think about what to do next and look at testing options :-)

FallingInReverse profile image
FallingInReverse

Keep doing what you’re doing until your next blood test (when will that be?)

Add a CRP-hs measure to your next iron panel. CRP measures inflammation (like what happens when we have a virus or cold for example). Inflammation causes ferritin to rise temporarily, so you need this to assess your real ferritin levels.

And find one that includes a TIBC measure. You have transferrin, but a TIBC would say how much of that is available for more iron capacity.

Have tried eating more iron rich foods and got a bit of change in serum ferritin 47 up to 53 ng/mL (20-204).

Bit concerned with my iron studies though

Serum iron level 14.8 umol/L (4.4-27.9)

Serum transferrin 2 g/L (2-3.2)

Transferrin sat index 29% (0-55%)

Do these mean I should take iron supplement?

I can see why you’re concerned but although it’s not great and you definitely need to improve, we need more info before/if you start supplementing.

Iron is fast moving up and down, but even so, yours is about 45% through range and we want to see between 55-70%.

Transferrin saturation needs to be a minimum of 30% and optimally 35-45%. So yours is ok while you continue to focus on eating more iron-rich foods.

The caveat here is that your transferrin is on the low side, so although they are well saturated with iron, these two numbers together are a reflection of your overall need for more iron.

Your ferritin increasing is initially a great sign - with the CRP caveat. The increase either means that you have enough iron for your cellular needs for your body to be comfortable throwing some over to storage. Or, you have some inflammation. We won’t ever know.

So keep eating more iron. If that includes liver or pate, limit it to one serving a week to avoid Vit A toxicity (a very real thing!). Get a better iron panel with CRP and TIBC, and let us know when you plan to get your next test.

BlueDaisy22 profile image
BlueDaisy22 in reply toFallingInReverse

Thank you that is really helpful. I didn't know what the crp was looking at. It was included in the Oct 24 tests but was plasma C reactive protein <1 mg/L (0.00-5.00) is that the same thing? I have various fbc readings on this latest test results but not sure what relates to what! They didn't do crp this time.

FallingInReverse profile image
FallingInReverse in reply toBlueDaisy22

Ha! In my early days of diagnosis I rmemeber how hard it was to keep track even of the difference ways FT4 was written.

Yes! That is indeed CRP.

So Oct 24 was the lower figure?

Also humanbean Is better at interpreting iron in a CBC.

But in my quick look, with your normal MCV and high in range MCH, combines with your ferritin and transferrin saturation, this suggests that while your iron stores are on the lower side, they are not severely depleted.

BlueDaisy22 profile image
BlueDaisy22 in reply toFallingInReverse

Oh phew! (Re the iron not being too bad.) Yes the crp in Oct just says <1.Thank you :-)

helvella profile image
helvellaAdministrator

BlueDaisy22,

Trying to help - your attempt at calling out to people failed. :-(

You need to start the name immediately after @ - no space!

I'll edit your original post to get them to work. They will go blue!

helvella - How to "mention" or "callout"

Having read a post or reply, I've noticed that you might wish to alert other members to your post or reply. For example, you might have said so, or asked how to do so, or tried but it has not worked.

This is an explanation and screen recording showing how to callout members in posts and/or replies so they get alerted.

This is not to say you have done anything wrong. This is meant to help you by pointing out this option, and help to do so, not to criticise.

There is no need to reply! If it was helpful, ticking the "Like" button lets me know.

Last updated 03/01/2025

Link to blog:

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