I have Hashimoto’s, am on T4/T3 combo and get migraines. Have been told I can’t move onto migraine preventative injections etc unless I try 3 prophylaxis meds first. Propranolol and Amytriptaline no help, so now they say try Candesartan.
I have enough bad reactions with many medications, so am wary to do so, but I must give it a go. I was wondering if I need to take Candesartan well away from thyroid meds? I split my T3 into 3 doses, so hopefully it won’t interfere with that. I take my Levo an hour before lunch as (when they strike) I will usually start the day with a bad head and can’t take the Levo until the migraine is sorted.
Any comments welcome and appreciated
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Lovecake
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Yes, that is for that. Evenings are more difficult as I take magnesium for my bones and migraines. That also helps to relax me (hence migraine help).
As long as no one comes up with “you must take at the opposite end of the day to levo”, I should be fine.
I have blood test next week, so won’t start anything before those results and have chatted to my GP. Thankfully she is lovely, and she knows I have issues with reactions to medication
I’m currently in hospital and have just been started on Candesarten. Day 5
Take NDT at 6 am and BP meds about 8 am . Researched possible interactions. None
Hi, thanks for your reply. Sorry to hear you are in hospital. I hope it’s nothing serious and you will be able to go home soon.
I have normal BP, but this is what the neurologist messaged to my GP. If I don’t try it then they will be unlikely to let me have what I’d call the “proper” migraine meds. I know that these work for some, but they wouldn’t have invented better things if they weren’t needed. As I cannot afford to go private with this I will have to follow the NHS rules. Glad you have no problems with the Candesartan and hope it helps you 😊🧁
I’m on levo only and been taking candesarten for the last 18 years and not had any issues that i’m aware of…..i usually take the candesarten about 90 mins after the levo. I also used to get frequent migraines which have reduced significantly since taking b12 and vit d supplements.
Thanks SD. Yes, I always follow the testing protocol. I’m going to see what my bloods come back next week as and then decide on an increase. I don’t want to reduce T3 as I convert slowly and run out of energy too quickly. But I may up my levo a bit. I usually do this myself, then tell the endo what I’m on. I haven’t altered T3 for several years now.
I have Thorne basic B. But it does irritate my bladder (of which I have enough issues with needing to go rather quickly). Also have some methyl folate. And seem to tolerate the Betteryou B complex spray fairly well which does increase my B12 well.
This may not be relevant but out daughter was taking daily preventative migraine meds for a number of years. However, a visit to Dr Sarah Myhill on another issue dealt with migraine, too. Dairy was the culprit. Removed dairy from her diet+the migraines ceased! Will leave this with you+trust you get the relief you need .
My daughter takes her first dose of T3 at 6am, candestatin at 7:30 and levo at night. She takes magnesium split 3 ways thru the day. She also has immigrin injections which she uses for her migraines. She often wakes early with a migraine so I would think she possibly doesn't always leave an hour betw oral immigrin and the t3. The neurologist has tried to get her to have Botox inj but she is not keen as they need repeating every 3 months. She has had a nerve block but not sure if this has helped or whether they are now less frequent because she has her folate, b12, vit d and ferritin optimal. She also supplements the above plus selenium and zinc.
Thank you. All helpful. Migraines are so frustrating. Often not knowing what has triggered it. I have years of daily notes to try and find obvious triggers and patterns, but nothing is obvious (other than the usual big things like, strong perfumes, spicy foods, alcohol, like sensitivity, weather, heat, cold, irregular food, lack of water etc etc which I avoid)
I hope your daughter finds some relief more often - it’s all we hope for ☺️🧁
My dr changed my bp med to Candesartan. Iam not good with medication and I ended up in hospital which was caused by Candeartan and as soon as I went back to old B P med I recovered and went home, I would never take it again
Sorry to hear this. I cannot take generic sumatriptan. Makes me have a terrible migraine with 7hrs of vomiting. Then 4 days to recover. You wouldn’t believe how many times a doctor or pharmacist has tried to persuade me to have the generic as opposed to the original Imigran.
I cannot tolerate synthetic estrogen either. Gives me terrible headache pain. I need estrogen and have to have body identical only.
Cannot take paracetamol or codiene either. Neither can my mum.
I am nervous to try the Candesartan, but I have to try it. I will start on a tiny dose of 4mg, so if I have a reaction I hope it will not be bad.
Hi, you mentioned that that you have got a problem with lots of triggers to your migraine and having reactions . Could be histamine /mast cell problems, chemical sensitivity ?
Thanks, I’ll look into it. Although I can’t do a lot about masts. We do get 5G in the front of our bungalow, but the mast is not close by. Would take me 7 minutes to walk there. I use very little chemicals. Have Koh cleaning products which are all natural. And also use vinegar and tea tree oil. And I have peppermint oil that I put in a spray for freshness (and to hope it keeps spiders and mosquitoes away 😂).
Hi, thanks for your reply. Oh 😳 I see what you mean, mast 5G could be a trigger too, 7 minutes walk is not to far away and 24/7. But I meant,, mast cells,,in human body, that are responsible for allergies sensitivities reactions. They response to a foreign triggers and in releasing histamine, substance that is normaly has a lot of functions in human body, but when it is to much and for some reasons our body can't get rid of, it coursing problem -- migraine, allergies, sensitivities. I do suffer from similar problems and reacting to the triggers you have mentioned. The peppermint oil and tea tree oil are ones of the triggers for me. My reactions and migraine have subsided a lot by avoiding them as well as some the others like spices . Perhaps they are the culprit of your migraine. Hope this may help. Wish you well.
Hi, I get what you mean now. I pretty certain I don’t have a histamine issue. I’ve done a food intolerance test. Was only slightly intolerant to milk, beef and egg whites. I rarely have milk items as it gives me tummy ache, but not a bad head. Beef is ok in small doses and eggs are ok. But it’s good to look at other items. I’m fine with the peppermint and tea tree oil. Chilli is a no. I used to love them till they decided that they would not like me. A fresh hot chilli pepper on a salad, yummy, but no more - nose closes up and I get a severe pain in my head. We don’t have sizzling fajitas in this house due to the chilli being in the air and setting me off.
One good thing about not tolerating perfume is that we can tell my mother in law “no perfume or we don’t see you” 🤣 She likes her perfumes so I tend to stay well clear 🫣
Hi, thanking you for your info, good to hear that you don't have histamine issue.Yes ,I know similar feeling,,chilli in the air,, 🌶️🚫 and curry or herbs. In my case, started with hay fever then herbs and perfumes then gone worse over the years to all sorts of spices, food additives,environmental fumes , some medications, not tolerating well heat or cold.
That made me laugh --,,no perfumes or we don't see you,,😊. Keep well.
update: decided to go for it. Checked all the ingredients when I had picked up the prescription. Just taken my 3rd tablet today. No initial bad reactions, so I’m pleased so far. Whether it makes a difference to the number of migraine days, time will tell
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Help im confused again!! Anyone know the science of taking t3 and t4 together!??
Issues with taking thyroid mads 
Taking a bit of Levo with your T3.
Advice with T3 / Levo combo pls
