Magnesium as ozonated magnesium oxides

[Lottyplum]

Hello again. Slow Dragon said that there needs to be 4 hours after T4 or T3 before taking Magnesium. I take magnesium from ozonated magnesium oxides with 3% potassium before bed to help with any constipation that still lingers a little. I asked the company about their product and they said they don't use magnesium hydroxide in their formula so I'm good to go+don't need to keep the 4hr difference! Any thoughts on this as I'm still a little iffy about following this advice. I'm trying to fit in my 3 doses of T3 on an empty stomach+ supplements and fit in meals!! Thankyou.

[helvella Administrator Thyroid UK]

I suspect they are answering a specific point and completely ignoring a more complete picture.

See Table 1 in the link below. And open in a separate window.

Look for Aluminum hydroxide/Magnesium oxide Basic antiacids

Medications and Food Interfering with the Bioavailability of Levothyroxine: A Systematic Review.

europepmc.org/article/MED/1...

We need to consider not just the precise chemical name of the substance but the fact that substances like magnesium oxide could react with the hydrochloric acid in the stomach. I suggest that both magnesium oxide and magnesium hydroxide can react with hydrochloric acid. (But not being a chemist, am not entirely sure what will happen.)

[Lottyplum in reply to helvella]

Thanks very much. Will be having a read of your links. I did give a full account in my email to the company that I’m taking T4/T3 combo, T3 being taken 3 times a day and when first and last dose taken (which means I need to wait until midnight to take their magnesium product which works so well and now with T3 only need a small amount). As years of constipation due to Hashimotos has led to diverticulitis I am very careful not to get constipated. Even travelling an hour’s distance to stay with friends or relatives would result in my insides seizing up! I have to say that inclusion of T3 has had a wonderful effect. Thank you again for such a speedy response on a Sunday evening!

[Eton in reply to Lottyplum]

lottyplum can I ask what magnesium supplement you take please?

[FallingInReverse in reply to Eton]

In this post are links to a description of all the different types of magnesium, the different things they target, and other people’s input on what they use and how much.

Thought it might be helpful!

healthunlocked.com/thyroidu...

[Lottyplum in reply to FallingInReverse]

Thankyou very much.

[Lottyplum in reply to FallingInReverse]

Signed up for Dr Kickers newsletter. His articles on magnesium and autoimmune issues are excellent. Need to read again+inwardly digest. Also forwarded to our daughter who has psoriasis, low stomach acid and is a stress head! Thank you again!

[Eton in reply to FallingInReverse]

Many thanks. Very helpful.

[Eton in reply to FallingInReverse]

Many thanks.

[Lottyplum in reply to helvella]

Here are Poopdoc Ingredients:

Magnesium (from ozonated magnesium oxides) 1035mg (259% daily value)

potassium (from potassium Citrate) 99mg (3% daily value)

[Lottyplum]

It's an American product that I buy here in the UK after seeing the owner of the company, Scott Olsen, talk about it+how he came to produce it on Know the Cause, a TV+YouTube programme. It's called Poopdoc - the No.1 product for the No.2 problem!! It's gentle on your tummy, no griping - and it works. Just look on his website as there's lots of info there about constipation+it's affects on your body, Poopdoc.com. You can get it here in the UK from one outlet. If you want further details +email contact, just let me know.

[FallingInReverse in reply to Lottyplum]

I looked in the website but could t see the label - what type of magnesium and how much is in that supplement?

[Lottyplum in reply to FallingInReverse]

Will check when home as presently out and about!

[Lottyplum in reply to FallingInReverse]

I've just ordered a new bottle of Poopdoc but if you'd like a sample pack for yourself just contact [e-mail], he is sorting out a website that should be available soon so you can order directly here in the UK.

[SteveT3]

I don't think a time gap of 4hrs regarding magnesium when taking medicine is relavant. What matters more is having sufficient stomach acid and good digestive transit.

Magnesium absorbs quickly, as long as you take it on its own away from food. If you have a digestive problem or impairment, as I do then it matters.

I take magnesium with water well away from a meal because if I don't it causes digestive upset by attracting too much water and speeding up my transit at the wrong time, like when I have a meal.

Much like having fruit or any other type of natural laxative they are best taken on their own away from a substantial protein meal. They digest quickly. Its not generally good to eat quick digesting food with slow digesting food because otherwise it sits in the stomach churning away for hours and can be bloating..

I also avoid taking magnesium during the day when I need energy because its sedative. I either take it first thing in the morning, or last thing before sleep.

If you have such low stomach acid that you need to take it with a meal like a rich protein meal then that goes against that principle. The point is, a 4hr gap is not a relavent restriction. Your body is unique. You will need a custom approach.

[Lottyplum in reply to SteveT3]

As I have Hashimotos I am assuming I have low stomach acid. I also have diverticulitis and constipation has been the bain of my life, tho T3 has improved it greatly. I find it difficult fitting in meals+supplements+T3x3 times a day on an empty stomach with the necessary time gaps for good absorption, hence my queries!🥴

[FallingInReverse in reply to Lottyplum]

I needed to look this up, which I embraced as it made me challenge that conventional wisdom about magnesium and Levo/Lio.

I too recently did the usual deep dive on magnesium. Per the forum and everything else I’ve read, Magnesium of any kind interferes with the absorption of exogenous thyroid hormones and it does need 4 hours.

Was going to give a quick answer, but then wondered what it might be that makes what the magnesium company say that. What grain of truth is in there . I wondered , why would there be a difference between magnesium oxide and magnesium hydroxide.

Here’s what I gathered:

Ozonated Magnesium Oxides: This is often marketed for its ability to release oxygen in the digestive tract, which helps with constipation. The claim that you don’t need to maintain a 4-hour difference between taking this magnesium product and thyroid medications might be based on the company's focus on how their product interacts within the gastrointestinal system vs other sites in the body. But other places magnesium could interfere potentially include metabolic pathways, enzyme systems, or receptors within the body's cells and tissues outside the GI tract, like the liver or kidneys.

The company ignores the full complex chain, annd only focuses on the absence of a negative impact on medication absorption in the gut.

Absence of Magnesium Hydroxide: This is a common ingredient in antacids and laxatives, which is commonly known to interfere with Levo because it lowers stomach acid, but its only one small step and ignores how there are many other places along the way that the presence of magnesium in the gut impacts how things get absorbed and used.

What do you think!

[arTistapple]

T3 is not a fussy hormone, according to lots of entries on the Forum. It does not have to be taken on an empty stomach etc. T4 yes, it needs to be taken away from everything else. So that could cut down on your worries and organisation of your supplements etc.

[Lottyplum in reply to arTistapple]

Phew, what a relief! Been tying myself in knots with gaps for food+supplements!

[FallingInReverse in reply to Lottyplum]

I would temper this with my layman’s view - open to all challenges! - that this might be the case with exogenous T3 in the stomach… but it doesn’t fully address all the other places in your cells that Lio is used.

I always try to imagine when I take my Levo and Lio, knowing it will take that hour to get through my stomach and make its way to the small intestines to be absorbed … then the blood and cellular processes kick off.

If it helps, magnesium is fine with iron and actually works with D.

With T3 if you really can’t do 4 hours, how much can you do?

Let me know what you think and how your schedule sorts out!

[Lottyplum in reply to FallingInReverse]

So, had blood tests this morning+as GP has snook in thyroid bloods in the past I didn't take T4 + T3 til after appt@8.45. So waited another hour+a half to eat. Took my T3@1.45pm+lunch@2.30. will take my final T3@about 7.30-8pm+magnesium@midnight! Tomorrow will sort out a better with an earlier T3/T4 to the day!!

[FallingInReverse in reply to Lottyplum]

I’m getting bloods this week, will probably … ugh… not sure but I think adding magnesium is going to be my next move. Depending on what my Ts results are. But I am close to prioritizing adding Magnesium into my schedule, currently

7 am/waking Levo 75 mcg and Lio 2.5

Noon-ish Lio 2.5

5-8 pm Iron and Vit D (and the occasional glass of milk squeezed in here)

11pm/midnight Lio 5 mcgs

: )

[Lottyplum in reply to FallingInReverse]

I take my D3/K2 as a Better You spray. So much easier as can use anytime. I'm also thinking of using a magnesium spray during the day from same company as another option as, again, can use anytime. Will use my magnesium for any constipation between 11+midnight before bed! The things we have to do to keep on top of our game!!!

[Lottyplum in reply to FallingInReverse]

Here are Poopdoc Ingredients:Magnesium (from ozonated magnesium oxides) 1035mg (259% daily value)

potassium (from potassium Citrate) 99mg (3% daily value)