can any help?? : Hi all, I’ve not been on here... - Thyroid UK

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can any help??

HappyBadger profile image
17 Replies

Hi all,

I’ve not been on here in a very long time as I’ve had a lot of family issues. But I’ve had a lot of health problems of late like tiredness, sleep problems etc. so spoke to a new doctor and she suggested I do some bloods.

I was wondering if there was someone who could shine a light on them for me please??

the bloods were taken at 8am with no Levo for 24 hours before. I take 100mcg of Levothyroxine, am a vegetarian, gluten free too.

Here are my results:

Serum thyroglobulin level is 0.1 ug/L

reference range ( 3.5 - 77.0 )

Thyroglobulin autoantibodies was 4000 iu/mL

reference range is ( 115.0 )

TSH was 0.07 mu/L

reference range ( 0.27 - 4.2 )

T4 level 19.7 pmol/L

reference range ( 12.0 - 22.0 )

Thyroid peroxidase ab's is 600 ku/L

reference range ( 34.0 )

Serum vitamin B12 level 219 ng/L

reference range ( 197.0 - 771.0 )

Serum folate level 2.9 ug/L

reference range ( 3.0 - 20.0 )

Serum ferritin level 43 ug/L

reference range ( 13.0 - 150.0 )

any help would be greatly appreciated

Xx

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HappyBadger
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17 Replies
Jaydee1507 profile image
Jaydee1507Administrator

Please add reference ranges for each test - numbers in brackets after your result. These vary from lab to lab so are important.

HappyBadger profile image
HappyBadger in reply to Jaydee1507

Hi Jaydee1507, thanks for replying. I have put references ranges under each test in Brackets.

X

Buddy195 profile image
Buddy195Administrator

Was FT3 tested? It’s really helpful to have this alongside FT4 to see how well you are converting. Do you have readings for vitamin D? This is another key vitamin to support thyroid health.

Optimising key vitamins is really important with Hashimotos (antibodies show you are positive for this auto immune condition).

I aim for Folate to at least half way through range (yours is actually below range) I managed to raise my level using Thorne Basic B.

Likewise, I aim for Ferritin to be half way through range (Some point to 90-110ug as optimal) Look to improve your intake of iron from food in the first instance(I know this is more difficult to achieve in vegetarian diets). This website is useful:

dailyiron.net/

HappyBadger profile image
HappyBadger in reply to Buddy195

thank you so much for that. No , T3 or Vit D not tested even though I did ask for it . In fact I ask to have both tested every time I get bloods done.

It’s so frustrating when GPs just don’t listen to you. I’ll have a look at that website, thank you again. Xx

Buddy195 profile image
Buddy195Administrator in reply to HappyBadger

I looked at your previous post, where you were given great advice about improving key vitamins by the late (& greatly missed) Seaside Susie and others. It’s often worth rereading posts; I do this a lot myself!

If your GP doesn’t test FT3/ vit D, you need to look to test privately (as many members do, myself included).

SlowDragon profile image
SlowDragonAdministrator

Your vitamin levels are terrible

What vitamin supplements have you been taking

Serum vitamin B12 level 219 ng/L ( 197.0 - 771.0 )

As a vegetarian you need to supplement B12 everyday

Serum folate level 2.9 ug/L ( 3.0 - 20.0 )

Folate is deficient

Low B12 symptoms

b12deficiency.info/signs-an...

methyl-life.com/blogs/defic...

With serum B12 result below 500, (Or active B12 below 70) recommended to be taking a separate B12 supplement and a week later add a separate vitamin B Complex 

Then once your serum B12 is over 500 (or Active B12 level has reached 70), you may be able to reduce then stop the B12 and just carry on with the B Complex.

As Vegetarian or vegan likely to need ongoing separate B12 at least 3-4 times a week, or possibly daily

Highly effective B12 drops

natureprovides.com/products...

Or

B12 sublingual lozenges

uk.iherb.com/pr/jarrow-form...

cytoplan.co.uk/shop-by-prod...

B12 range in U.K. is too wide

Interesting that in this research B12 below 400 is considered inadequate

healthunlocked.com/thyroidu...

Low folate

supplementing a good quality daily vitamin B complex, one with folate in (not folic acid)

This can help keep all B vitamins in balance and will help improve B12 levels too

Difference between folate and folic acid

healthline.com/nutrition/fo...

Many Hashimoto’s patients have MTHFR gene variation and can have trouble processing folic acid.

thyroidpharmacist.com/artic...

B vitamins best taken after breakfast

Thorne Basic B recommended vitamin B complex that contains folate, but they are large capsules. (You can tip powder out if can’t swallow capsule)

Thorne currently difficult to find at reasonable price, should be around £20-£25. iherb.com often have in stock. Or try ebay

Igennus B complex popular option too. Nice small tablets. Most people only find they need one per day. But a few people find it’s not high enough dose

Post discussing different B complex

healthunlocked.com/thyroidu...

IMPORTANT......If you are taking vitamin B complex, or any supplements containing biotin, remember to stop these 7 days before ALL BLOOD TESTS , as biotin can falsely affect test results

endo.confex.com/endo/2016en...

endocrinenews.endocrine.org...

In week before blood test, when you stop vitamin B complex, you might want to consider taking a separate folate supplement (eg Jarrow methyl folate 400mcg) and continue separate B12

Post discussing how biotin can affect test results

healthunlocked.com/thyroidu...

helvella.blogspot.com/p/hel...

How other member saw how effective improving low B vitamins has been

healthunlocked.com/thyroidu...

Note that improving folate when B12 is very low is not a good idea. Taking folate before B12 is good enough can lead to severe neurological problems.

en.wikipedia.org/wiki/Subac...

It is vital if you intend to supplement both B12 and folate that B12 is started a week before the folate.

academic.oup.com/nutritionr...

The present review of the literature regarding B12 status among vegetarians shows that the rates of B12 depletion and deficiency are high. It is, therefore, recommended that health professionals alert vegetarians about the risk of developing subnormal B12 status. Vegetarians should also take preventive measures to ensure adequate intake of this vitamin, including the regular intake of B12 supplements to prevent deficiency. Considering the low absorption rate of B12 from supplements, a dose of at least 250 μg should be ingested for the best results.3

SlowDragon profile image
SlowDragonAdministrator

As a vegetarian with Hashimoto’s it’s going to be very difficult or impossible to maintain GOOD iron levels without supplements

Serum ferritin level 43 ug/L ( 13.0 - 150.0 )

cks.nice.org.uk/topics/anae...

Serum ferritin level is the biochemical test, which most reliably correlates with relative total body iron stores. In all people, a serum ferritin level of less than 30 micrograms/L confirms the diagnosis of iron deficiency.

Never supplement iron without doing full iron panel test for anaemia first and retest 3-4 times a year if self supplementing. It’s possible to have low ferritin but high iron

Test early morning, only water to drink between waking and test. Avoid high iron rich dinner night before test

If taking iron supplements, stop 5-7 days before test

Medichecks iron panel test

medichecks.com/products/iro...

Look at increasing iron rich foods in diet

Eg pumpkin seeds and dark chocolate, plus daily orange juice or other vitamin C rich drink can help improve iron absorption

List of iron rich foods

dailyiron.net

Links about iron and ferritin

irondisorders.org/too-littl...

davidg170.sg-host.com/wp-co...

Great in-depth article on low ferritin

oatext.com/iron-deficiency-...

drhedberg.com/ferritin-hypo...

This is interesting because I have noticed that many patients with Hashimoto’s disease and hypothyroidism, start to feel worse when their ferritin drops below 80 and usually there is hair loss when it drops below 50.

healthunlocked.com/thyroidu...

Posts discussing Three Arrows as very effective supplement (meat based supplement)

healthunlocked.com/thyroidu...

healthunlocked.com/thyroidu...

Iron patches

healthunlocked.com/thyroidu...

Thyroid disease is as much about optimising vitamins as thyroid hormones

healthunlocked.com/thyroidu...

restartmed.com/hypothyroidi...

Post discussing just how long it can take to raise low ferritin

healthunlocked.com/thyroidu...

Iron and thyroid link

healthunlocked.com/thyroidu...

Posts discussing why important to do full iron panel test

healthunlocked.com/thyroidu...

Good iron but low ferritin

healthunlocked.com/thyroidu...

healthunlocked.com/thyroidu...

Iron deficiency without anaemia

healthunlocked.com/thyroidu...

Ferritin over 100 to alleviate symptoms

healthunlocked.com/thyroidu...

healthunlocked.com/thyroidu...

Great research article discussing similar…..ferritin over 100 often necessary

ncbi.nlm.nih.gov/pmc/articl...

Low Iron implicated in hypothyroidism

healthunlocked.com/thyroidu...

Inflammation affecting ferritin

healthunlocked.com/thyroidu...

Updated reference ranges for top of ferritin range depending upon age

healthunlocked.com/thyroidu...

Thank you for your incredible patience while you have been awaiting the outcome of our ferritin reference range review. We conducted this with Inuvi lab, which has now changed the reference ranges to the following:

Females 18 ≤ age < 40 30 to 180

Females 40 ≤ age < 50 30 to 207

Females 50 ≤ age < 60 30 to 264

Females Age ≥ 60 30 to 332

Males 18 ≤ age < 40 30 to 442

Males Age ≥ 40 30 to 518

The lower limits of 30 are by the NICE threshold of <30 for iron deficiency. Our review of Medichecks data has determined the upper limits. This retrospective study used a large dataset of blood test results from 25,425 healthy participants aged 18 to 97 over seven years. This is the most extensive study on ferritin reference ranges, and we hope to achieve journal publication so that these ranges can be applied more widely.

SlowDragon profile image
SlowDragonAdministrator

You need vitamin D tested too obviously

Test twice yearly via NHS private testing service when supplementing

vitamindtest.org.uk

High thyroid antibodies

As you have autoimmune thyroid disease, aka Hashimoto’s are you on dairy free diet as well as gluten free?

You need TSH, Ft4 and Ft3 tested together

Suggest you retest 6-8 weeks after working on improving low vitamin levels

SlowDragon profile image
SlowDragonAdministrator

Only do private testing early Monday or Tuesday morning.

Just TSH, Ft4 and Ft3 test - £32

monitormyhealth.org.uk/thyr...

10% off code here

thyroiduk.org/testing/priva...

Monitor My Health also now offer thyroid and vitamin testing, plus cholesterol and HBA1C for £65

(Doesn’t include thyroid antibodies)

monitormyhealth.org.uk/full...

10% off code here

thyroiduk.org/testing/priva...

HappyBadger profile image
HappyBadger in reply to SlowDragon

wow!! Loads to read through. Thank you. ☺️

My GP has been prescribing ferrous sulfate 200mg once a day and folic acid 5mg one a day. He only prescribed these because I was adamant that I was low. These don’t seem to be doing much for me though. I was taking the Thorne basic B but the GP said I should stop as my b12 was getting too high.(nowhere near the top of the range) oh and I was as told my calcium level was high too.

I’m now seeing a different GP on Monday to discuss all my thoughts on my vitamin levels and thyroid levels. And I’m going to ask for a Vitamin D test too.

Thank you so much for all your advice xx

SlowDragon profile image
SlowDragonAdministrator in reply to HappyBadger

and folic acid 5mg one a day.

Once you finish prescription folic acid then start and continue daily vitamin B complex

GP said I should stop as my b12 was getting too high.(nowhere near the top of the range)

As a vegetarian you are always going to need daily B12

GP has been prescribing ferrous sulfate 200mg once a day

May not be enough

GP should retest in 3-4 months

Sparklingsunshine profile image
Sparklingsunshine in reply to HappyBadger

I had very low iron levels several times, my ferritin dropped to 6, I was taking iron tablets through much of my childbearing years. I was prescribed ferrous fumarate 3 times a day, iron sulphate can be really harsh on the digestive system, with wind and bloating very common.

Ferrous fumarate is better tolerated and there is also ferrous gluconate, which is gentler still. You will probably need more than one tablet a day to get levels up.

Bertiepuss profile image
Bertiepuss in reply to HappyBadger

Just spotted something to add to your list when you talk with your GP. You mentioned high calcium levels - could point to a parathyroid issue (not thyroid, another set of glands nearby) you would need to have parathyroid hormone levels tested in the same blood draw as calcium and vit D to see their relationship to each other as they interact. I am not well versed on this but was something pointed out to me in one of my own posts. If you can face some more reading (I can see admins have already given you lots of work to do 😁) I found this site quite informative. hyperparathyroiduk.com/

Jaydee1507 profile image
Jaydee1507Administrator

Likely the worst issue you are facing is low/deficient vitamin levels.

B12 & ferritin do suffer particularly if not eating meat.

For B12, start with a methyl B12 sublingual spray or lozenge for a week, then add a good B complex. Once you run out of the separate B12 and you know your level is good just continue with the B complex.

cytoplan.co.uk/vitamin-b12-...

amazon.co.uk/Better-You-Boo...

Folate will be covered by the B complex:

Slightly cheaper options with inactive B6:

amazon.co.uk/Liposomal-Soft...

Contains B6 as P5P an active form:

bigvits.co.uk/thorne-resear...

healf.com/products/basic-b-...

Explanation about the different forms of B6:

helvella.blogspot.com/p/hel...

B complex comparison spreadsheet:

healthunlocked.com/thyroidu...

Ferritin - aim for 90-100. You may need to take a supplement to get you there.

NHS easy postal kit vitamin D test £31 via

vitamindtest.org.uk

Your FT4 is at 77% of its range and could be improved but we have no FT3 result.

GP might want you to reduce with a low TSH and you should argue to stay on your current dose.

Suggest you get private bloods run to include FT3 & D3.

HappyBadger profile image
HappyBadger in reply to Jaydee1507

Thank you so much for all your advice. I’ve got a lot of reading to do☺️

jgelliss profile image
jgelliss

What a phenomenal connection. Thank you for sharing it with us. When I'm not on enough T3 I get lower back discomforts. And when I add 5mcg T3 I feel like it's all gone the discomforts. Thank you again for this information.

Eddie83 profile image
Eddie83

Your TG and TPO antibodies are quite high. You won't feel well while nursing Hashimotos. If you can't get testing for common food allergies, you could try dropping gluten, dairy, and soy from your diet to see if the antibody levels drop.

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