TPO results : Hello, just got my TPO results 49... - Thyroid UK

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TPO results

ScarboroughFair profile image

Hello,

just got my TPO results 498 (0-34) so I think that means antibodies damaging my thyroid. Is that very high or normal with hyper moving to hypo?

My results from last week were:

TSH 0.02 (0.27-4.2)

FT4 33 (11.1-22)

FT3 10.7 (3.1-6.8)

Thank you

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ScarboroughFair profile image
ScarboroughFair
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10 Replies
PurpleNails profile image
PurpleNailsAdministrator

Antibodies are positive.

TPO confirms autoimmune but not specifically Graves. TPO appear in both Hashimoto’s & Graves.

Just to clarify - TPOab aren’t attacking your thyroid. Your own immune system is attacking (& or stimulating) thyroid (the damage caused means that substances that are usually in thyroid are released into your system). The antibodies are produced to “clean up” the debris that should be there. So shows autoimmune is occurring.

TSI & or TRab should be tested.

Has doctor suggested carbimazole / PTU, beta blockers or referral to endo as yet?

ScarboroughFair profile image
ScarboroughFair in reply toPurpleNails

Thanks for clarifying. Seeing my GP this afternoon and will see what she suggests

SlowDragon profile image
SlowDragonAdministrator in reply toScarboroughFair

You should have TSI or Trab antibodies tested for Graves’ disease as next step

Plus vitamin D, folate, ferritin and B12

Also coeliac blood test

nice.org.uk/guidance/ng20/c...

1.1 Offer serological testing for coeliac disease to:

people with any of the following:

persistent unexplained abdominal or gastrointestinal symptoms

faltering growth

prolonged fatigue

unexpected weight loss

severe or persistent mouth ulcers

unexplained iron, vitamin B12 or folate deficiency

type 1 diabetes, at diagnosis

autoimmune thyroid disease, at diagnosis

irritable bowel syndrome (in adults)

first‑degree relatives of people with coeliac disease.

ScarboroughFair profile image
ScarboroughFair in reply toSlowDragon

Hi Slow Dragon, I’m hoping the endocrinologist will do those tests. I’m b12 deficient but good levels at the moment, vitD is pitifully low so taking every day now

ScarboroughFair profile image
ScarboroughFair in reply toPurpleNails

Been given 10mg carbimazole and referred to endocrinology.

GP says she hasn’t seen someone with hyperthyroid and symptoms of fatigue before. She has now!

SlowDragon profile image
SlowDragonAdministrator in reply toScarboroughFair

GP says she hasn’t seen someone with hyperthyroid and symptoms of fatigue before.

Because it could be early stage Hashimoto’s not Graves’ disease

Hashimoto’s frequently starts with transient hyperthyroid results before becoming increasingly hypothyroid

Have you had cholesterol levels tested (high cholesterol = hypothyroid)

Ferritin levels need testing too

Generally higher ferritin levels with Graves’ disease and lower levels with Hashimoto’s

How low is/was vitamin D

How much vitamin D are you taking

ScarboroughFair profile image
ScarboroughFair in reply toSlowDragon

I’m taking 25mg of vit D, level is just below range but not in the dangerous area

Lalatoot profile image
Lalatoot in reply toScarboroughFair

Fatigue and hyperthyroidism is a common combo. Muscle weakness, a racing mind and a fast irregular beating heart takes its toll after a while and you end up so fatigued that it is hard to function. I found stairs particularly challenging when I was hyperthyroid. I struggled to get up them and then felt I was going to collapse at the top.

ScarboroughFair profile image
ScarboroughFair in reply toLalatoot

That’s the stage I’m reaching. I walk a lot and do Pilates but get out of breath now if I can’t have regular lie downs. Work isn’t too bad because I’m sitting all day, but standing up and walking anywhere makes my leg muscles scream! Did you improve with medication?

Lalatoot profile image
Lalatoot in reply toScarboroughFair

Yes but I was on 40mcg carbimazole spread throughout the day.

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