I recently had a Medichecks Advanced Thyroid Test done and would appreciate some help with analysing it please. I'm currently on 75mg of Levo daily and take Thorne Basic B vitamins approximately 4 times per week. My feeling is that all is okay apart from the Vit D?
TSH 1.05 (0.27-4.2)
Free T3 3.84 (3.1-6.8)
Free Thyroxine 17.4 (12-22)
Ferritin 114 (13 - 150)
Folate - Serum 14.04 (3.89-19.45)
Active B12 97.2 (37.5-150)
Vitamin D 38 (50 -200)
Thyroglobulin Antibodies 12 (range less than 115)
Thyroid Peroxidase Antibodies less than 9 (range less than 34)
Any wisdom you have to share would be great. Many thanks for your help.
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SilverSavvy
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Hi Slow Dragon. Thanks for your reply. Haven't been taking any Vit D supplement as I walk outside every day.
Same brand of Levo (after much fighting to get it) throughout the past twelve months. Have gone up to 75 within past three months or so.
Test done exactly as you recommend: all vits laid off for 1 week prior, done 8am in morning , last Levo taken the morning before.
I'm feeling better than I was after starting on Basic B but I still have very great trouble not putting on weight, my hair is falling out, almost no eyebrows now. Get very tired by pm if I don't watch how much I am doing during the day. Stress shreds me.
Was diagnosed with early menopause at 39, family history of pernicious anaemia, thyroid issues and bowel cancer. If any of that is relevant?
So see/contact GP and request next increase in levothyroxine
Approx how much do you weigh in kilo
Even if we frequently don’t start on full replacement dose, most people need to increase levothyroxine dose slowly upwards in 25mcg steps (retesting 6-8 weeks after each increase) until eventually on, or near full replacement dose
Consider starting levothyroxine at a dosage of 1.6 micrograms per kilogram of body weight per day (rounded to the nearest 25 micrograms) for adults under 65 with primary hypothyroidism and no history of cardiovascular disease.
In the majority of patients 50-100 μg thyroxine can be used as the starting dose. Alterations in dose are achieved by using 25-50 μg increments and adequacy of the new dose can be confirmed by repeat measurement of TSH after 2-3 months.
The majority of patients will be clinically euthyroid with a ‘normal’ TSH and having thyroxine replacement in the range 75-150 μg/day (1.6ug/Kg on average).
The recommended approach is to titrate thyroxine therapy against the TSH concentration whilst assessing clinical well-being. The target is a serum TSH within the reference range.
……The primary target of thyroxine replacement therapy is to make the patient feel well and to achieve a serum TSH that is within the reference range. The corresponding FT4 will be within or slightly above its reference range.
The minimum period to achieve stable concentrations after a change in dose of thyroxine is two months and thyroid function tests should not normally be requested before this period has elapsed.
That's all really great advice - and info to address the doctor with. I think I will start on the VitD K7 (easily absorbed version) as soon as I can get some. Weight wise, 1.6 per kilo leaves me nowhere near enough at 75mgs alas. Probably need more like 125!
Thank you so much for all of this.
Now all I have to do is get them to file the Medichecks results. I was trying to save the NHS money by doing them myself but I heard on here that they won't always pay attention/add them to notes. Sometimes my doc listens, sometimes not. Still, I'm not prepared to get bowel cancer just to fall in line with them...
Hi Slow Dragon, yes I did as you suggested and asked for an increase which was granted about a month ago (on the basis of ongoing symptoms) when I could get to speak to the doc. Because I don't do so well on sudden Levo increases, I've been taking 87.5 for a few weeks and have now gone up to 100 this week. So far so good. Things seem to be improving although as per earlier post today, hair and skin still dry but I am hoping that will change soon. Average daily heart rate has increased slightly showing metabolic uptick and other symptoms viz digestion gradually improving again which is usually my first sign of recovery.
I'm supplementing Vit D with K2 sublingually, plus methylated B complex (or sometimes just B12 and Folate as too much Biotin doesn't seem to agree with me.
It is indeed time for more blood tests but I won't get anything except TSH from the surgery so it's back to Medichecks and will post findings when I do.
Thanks so much for all your help. It is really valuable to me.
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