Thybon Henning doesn’t contain acacia?! - Thyroid UK

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Thybon Henning doesn’t contain acacia?!

hjh88 profile image
10 Replies

Sharing for info but also a question around changes to formulation.

I’ve recently had my T3 increased which meant moving to Thybon Henning 20s. Since I’m allergic to acacia, I set about trying to find out if it contained it. I spoke to 2 pharmacies (SmartWay and Roseseway Labs) as well as doing my own online research and the verdict was it contains acacia powder.

The cost difference between the Thybon (about 50p a tablet) and the next cheapest without acacia (Teva at over £3 a tablet) was so large that I agreed with my doctor to at least try the Thybon. My previous acacia reaction was mild and I’ve generally found my allergy symptoms improving. If I didn’t react it would save a fortune!

So the tablets arrive, I glance over the leaflet included but am surprised to see no acacia listed in the ingredients. Those listed are: liothyronine hydrochloride, pregelatinized corn starch (maize), corn starch, microcrystalline cellulose, sodium carbonate, sodium thiosulfate 5H2O (Ph. Eur.), colloidal silicon dioxide, hydrogenated castor oil. Picture attached and I’ve been careful to include the company info too.

Is this likely to be a translation issue online? Or has the formulation changed recently?

Either way, I’m very pleased it’s not going to cost quite so much for now and thought it might be useful to share in case anyone else is in the same boat!

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helvella profile image
helvellaAdministrator

It has never had acacia. I have no idea why anyone would say it did!

(In a facetious moment, which is unfair on many individuals: If you want to know about a medicine ask a pharmacist. Then go and look for yourself!)

From Sanofi's own website, just a few minutes ago (Sanofi own Henning):

6. Inhalt der Packung und weitere Informationen

Was Thybon 20 Henning enthält

Der Wirkstoff ist Liothyroninhydrochlorid.

1 Tablette enthält 20 Mikrogramm Liothyroninhydrochlorid.

Die sonstigen Bestandteile sind: vorverkleisterte Stärke (Mais), Maisstärke, mikrokristalline Cellulose, Natriumcarbonat, Natriumthiosulfat 5 H2O (Ph. Eur.), hochdisperses Siliciumdioxid, hydriertes Rizinusöl

mein.sanofi.de/produkte/thy...

A Google Translate of the above:

6. Contents of the pack and other information

What Thybon 20 Henning contains

The active substance is liothyronine hydrochloride.

1 tablet contains 20 micrograms liothyronine hydrochloride.

The other ingredients are: pregelatinized starch (maize), maize starch, microcrystalline cellulose, sodium carbonate, sodium thiosulfate 5H2O (Ph.Eur.), colloidal anhydrous silica, hydrogenated castor oil

And an old (2017) official English translation of the product documentation:

dropbox.com/s/ccfr0tnmr7nom...

Links to product documents for many, many products are in my medicines document - see around page 478 for Thybon Henning. For UK products, I have little tables which show which products contain lactose, mannitol or acacia. :-)

It is simply too much work to do the same worldwide, and not very helpful when official documentation is often not accessible so many boxes would be blank. :-(

helvella - Thyroid Hormone Medicines

I have created, and try to maintain, a document containing details of all thyroid hormone medicines in the UK and, in less detail, many others around the world.

From Dropbox:

dropbox.com/s/wfhrlmb5983co...

From Google Drive:

drive.google.com/file/d/11z...

Screenshot of English Thybon translation from 2017
helvella profile image
helvellaAdministrator in reply tohelvella

Just adding for emphasis:

Thybon Henning also has neither lactose nor mannitol.

The least expensive UK liothyronine, based on company list prices/what the NHS pay, is currently Roma capsules in 5, 10 or 20 microgram dosages. (£55, £65 and £55 respectively - for 28). Pharmacies will charge more for private prescription dispensing. That too is free of lactose, mannitol and acacia. Yes, more than the Thybon Henning.

hjh88 profile image
hjh88 in reply tohelvella

This is blowing my mind. One of the pharmacists I spoke to mentioned that he was doing what I was doing - googling to find the answer. At this point I assume we both found the same, incorrect source!

And thank you for the links to your documents. I had been using the uk ingredients matrix to search for alternatives as it happens! Very much appreciate that can’t be replicated for all of them. It’s a behemoth! And to be honest I think I’d hit my brains foggy limitations when it got to the more detailed information. Can’t believe I was so close and managed to miss it by a mile! It’s wild to me though that the pharmacy didn’t have better information. My cynicism grows again!

Thanks for setting me straight. What a relief!

helvella profile image
helvellaAdministrator in reply tohjh88

Perhaps pass on a link to my document to the pharmacist... :-)

sparkly profile image
sparkly in reply tohelvella

Glad i found this, answered my question about henning thybon

Hedgeree profile image
Hedgeree

Hi hjh88,

I highly recommend helvella's document. The information you needed was easily found there.

Best wishes.

hjh88 profile image
hjh88 in reply toHedgeree

Thanks Hedgeree! I had in fact been using it to compare uk brands but hit my limit in deciphering the wider document. Very annoyed with myself that I was within inches of finding the right answer. Clearly not yet on enough T3 😂

helvella profile image
helvellaAdministrator in reply tohjh88

Just did a couple of posts to try to help with big PDFs.

Viewing Long PDFs - Adobe Acrobat Reader DC

healthunlocked.com/thyroidu...

Viewing Long PDFs - macOS Preview

healthunlocked.com/thyroidu...

hjh88 profile image
hjh88 in reply tohelvella

Thank you helvella this is really helpful.

sparkly profile image
sparkly

I know this is an old post but just wondering what reactions you had to acacia? I'm wondering if my tongue swelling is a reaction to it

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