Hello folks, Can you help me with results? It’s been a long road tweaking medication.
I followed procedure for fasting etc and when to take doses as per advice given last week.
I currently take 100mcg levo and quarter 25mcg Tiromel at 3am, then 12 hours later another quarter of Tiromel. In addition, better you B12 spray (which I think I need to stop for a bit), better you but D/K2, turmeric capsules and 0.5 ml LDN in the evenings. I think someone said previously you should aim to get TSH near 1, which is getting there compared to last test in July. I do feel better but not pre hypothyroid - maybe will never get there! Am I right in thinking the T3 is helping? I still have concerns about ferritin, but GP is not interested and I do not have haemachromatosis. I cannot seem to get vit D levels above this!
Many thanks in advance for any advice you can give me, it’s been invaluable up until now and I am shocked at the treatment given by NHS now that my eyes are opened! Mar
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Mall1
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Ferritin obviously is elevated, sometimes this is caused by inflammation, and you do have Hashi's which can cause inflammation, but if this were the case I would have thought yur CRP would be raised also.
Folate is good.
B12 is very high and when you posted results inAugust 2020 it was over 150 and it was suggested that a B Complex rather than just B12 would be better, so you should have stopped the B12 then. Our B12 store is good for about 2 years so there is no need at all for you to be taking it at the moment. If you are taking a B Complex then just continue with that alone, remembering to leave it off for 3-7 days before any blood test to avoid false results.
Vit D has only increased from 67.9 to 77nmol/L and the Vit D Society and Grassroots Health recommend a level of 100-150nmol/L, with a recent blog post on Grassroots Health mentioning a study which recommends over 125nmol/L.
As you're having trouble raising it any further, how much D3 are you actually taking? Your current level suggests you need to take 3,000iu daily but if that isn't doing the job there's no problem increasing the dose but remember to test twice a year when supplementing with D3. You could also try changing the form of your D3 supplement, I've always got on very well with Doctor's Best D3 softgels, very pure with only D3 and extra virgin olive oil, and it raised my severely deficient level of 15 to 202 in 2.5 months.
Are you taking magnesium as a very important cofactor of D3? We need magnesium so that the body utilises D3, it's required to convert Vit D into it's active form, and large doses of D3 can induce depletion of magnesium. So it's important we ensure we take magnesium when supplementing with D3.
Magnesium comes in different forms, check to see which would suit you best and as it's calming it's best taken in the evening, four hours away from thyroid meds if taking magnesium as tablets/capsules, no necessity if using topical forms of magnesium.
When one takes T3 this tends to lower, often suppresses, TSH so it's surprising to see yours at 1.3,
FT4 is 47% through range and FT3 is 64.86% through range. When on combination hormone replacement it's very individual where each of us need these hormones. Some are fine with a low FT4 as long as FT3 is in the upper part of it's range, some of us need both FT4 and FT3 in the upper part of range, we can only experiment to find our sweet spot. So it's up to you what you want to do next. There is room for an increase but only you can decide whether you want to increase the Levo or the T3. If you increase Levo it will increase your FT4 and, to some extent FT3 as well depending on how much natural conversion you have. If you increase T3 then FT3 will rise and FT4 may decrease a little.
Thyroid antibodies
Presumably you knew that increased antibodies can suggest Hashimoto's.
I am taking 4 sprays of better you and forgot to mention 2 capsules of magnesium (autoimmune institute - although might have to change brand due to fillers.) if I take the soft gel D3 would I need to supplement with K2? I am keen to try and get levels raised for D3.
I will stop B12 immedately - but should I go back to doctor about ferritin? They don’t seem to care or be interested but it keeps flagging up.
The TSH has decreased but do you think this should be lower? I used to be on 125 mcg of levo and reduced this as per advice here to tweak T3 levels. Would adding the levo at 25 be ok or should I half the tab? I am currently quartering T3 tabs and know that sometimes fragments are different sizes as it is quite difficult to do. The peroxidase levels have normalised again - my last result alarmed me as I have never had that before - but you explained that it was hashimotos. I must admit that I feel so much better since starting T3.
if I take the soft gel D3 would I need to supplement with K2?
Yes, Vit K2-MK7 is an important cofactor of D3 so if you don't take a combined supplement then you need to take them both separately. D3 aids absorption of calcium from food and Vit K2-MK7 directs the calcium to bones and teeth where it is needed and away from arteries and soft tissues where it can be deposited and cause problems such as hardening of the arteries, kidney stones, etc. 90-100mcg K2-MK7 is enough for up to 10,000iu D3.
D3 and K2 are fat soluble so should be taken with the fattiest meal of the day or some dietary fat, D3 four hours away from thyroid meds if taking D3 as tablets/capsules/softgels, no necessity if using an oral spray. K2-MK7 2 hours away from thyroid meds.
For Vit K2-MK7 I like Vitabay or Vegavero brands which contain the correct form of K2-MK7 - the "All Trans" form rather than the "Cis" form. The All Trans form is the bioactive form, a bit like methylfolate is the bioactive form of folic acid. Both are German makes, often found on Amazon or Ebay but sometimes go out of stock and there is a wait for them to come back. It is possible to buy direct but their websites are in German.
If looking for a combined D3/K2 supplement, this one has 3,000iu D3 and 50mcg K2-MK7. The company has told me the K2-MK7 is the Trans form
When looking at alternatives to the spray, don't consider tablets or capsules as these are the least absorbable of the different forms.
but should I go back to doctor about ferritin? They don’t seem to care or be interested but it keeps flagging up.
Maybe see a different GP, explain that your level always seems to be raised but it only seems to be you that is concerned, not any other doctor that you have seen. If again the GP is not concerned, I'd be inclined to ask why there are ranges if they're ignored and can they explain why such a raised level is of no concern.
The TSH has decreased but do you think this should be lower?
This all depends on you and how you feel. All we can say is that when people take T3 this tends to lower/suppress TSH. If your TSH doesn't and you feel well then there's nothing to worry about.
Would adding the levo at 25 be ok or should I half the tab?
At this stage any dose changes really would be best to be very small, I've had a dose change of Levo 5mcg daily make a difference. You're looking for your sweet spot so make very small changes, wait 8 weeks to retest and see how you feel then reassess if necessary.
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