Thyroid antibody test results -are they ok.

[puddlehead7]

Hello. I am having difficulty understanding my Thyroid results test. Can you help me please. My Thyroglobulin is 10. IU/ml. And peroxidase 9. IU/ml. Does this mean I have a good or a deficient Automune system. My Active B12 was 150 pool/L down from 256pmol/L done 2 months earlier. Thanks for any help.

[greygoose]

I don't think testing Hashi's antibodies - TPOab and TgAB - tells you anything about your immune system. It just tells you if you have Hashi's - but doesn't even tell you if you don't! You have it if your results are over-range. But, as you haven't given us the ranges, we can't tell if yours are positive.

[puddlehead7 in reply to greygoose]

Thanks for replying, sorry, I’ll give you more info. Thyroglobulin antibodies. In a range of 0- 115. IU/ml. I am 10

Thyroid Peroxidase in range. 0 - 34 lU/ml. I am 9. Does this mean I have good/bad or indifferent auto-immunity? - To thyroid problems or any other problem needing a good immune system. Arrow symbols pointing R or L on graphs mean nothing to me. I’d much appreciate your help. regards, from your puddlheaded member

[greygoose in reply to puddlehead7]

As I said before, TPOab and TgAB don't tell you anything about your immune system. They tell you if you have Hashi's, that's all. They are either positive or negative. If they are positive, you definitely have Hashi's. If the are negative - like yours - you could still have Hashi's for two reasons:

a) antibodies fluctuate all the time, they are low in this test but could be high in the next.

b) 20% of Hashi's sufferers never have over-range antibodies, and are diagnosed by ultrasound.

But, they don't tell you anything about any other autoimmune disease you might have, or might possibly develop. Every autoimmune disease has its own specific antibodies. So, testing TPOab and TgAB cannot tell you anything about the status of your immune system in general. It's just not possible.

[SeasideSusie Remembering]

puddlehead7

As ranges vary we need to know the reference range that came with your antibody results. It Thyroid Peroxidase antibodies often have a range of <34 or <60 but we do see some with a very low limit. Thyroglobulin antibodies often have a higher range of around <115 but again we have seen some with a very low limit. With the ranges we just can say I'm afraid.

If your result comes less than the upper limit of the range then that generally means your hypothyroidism is not autoimmune in origin. However, just to complicate things, it is possible to have autoimmune hypothyroidism without raised antibodies.

Why not post all the results, with their reference ranges, on the forum for members to comment.

[PurpleNails Administrator]

The antibodies look low. Antibodies are reacting to substances that shouldn’t be there so high is positive and low levels are negative.

When they are over the lab reference limit they are positive.

Range usually shown as either (0 - 34) or <34 for example

What was the range for B12? Then members can advise what levels are optimal.

[puddlehead7 in reply to PurpleNails]

Thankyou for your reply. My B12 is 150pmol/L after 3 months without any B12 sublingual or injection 2 months prior to this it was 256 after a year of sublingual self help. So it’s dropped a lot in 8weeks since not had any sort of B 12 help. I have today mailed the surgery with these results. Mmmmm? I could try another private check in another 2 months to see if it is still in range or still falling. We’ll see what comes back from the Surgery first. Medichecks said my Vit D and ferritin ok. I’ve asked them to look at the initial diagnosis made 10 years ago. Regards Yvonne

[SlowDragon Administrator]

Welcome to the forum

Are you currently taking any thyroid medication

Are you diagnosed as hypothyroid

Assuming yes….

How much levothyroxine are you currently taking

Do you always get same brand levothyroxine at each prescription

What vitamin supplements are you currently taking

For full Thyroid evaluation you need TSH, FT4 and FT3 plus both TPO and TG thyroid antibodies tested.

Also EXTREMELY important to test vitamin D, folate, ferritin and B12

Low vitamin levels are extremely common, especially with autoimmune thyroid disease (Hashimoto’s or Ord’s thyroiditis)

Also low vitamin levels more likely as we get older

Recommended on here that all thyroid blood tests should ideally be done as early as possible in morning and before eating or drinking anything other than water .

Last dose of Levothyroxine 24 hours prior to blood test. (taking delayed dose immediately after blood draw).

This gives highest TSH, lowest FT4 and most consistent results. (Patient to patient tip)

Please add ranges on antibodies results

Assuming they are negative, doesn’t rule out Hashimoto’s

20% of Hashimoto's patients never have raised antibodies

Request ultrasound scan of thyroid

healthunlocked.com/thyroidu...

Paul Robson on atrophied thyroid - especially if no TPO antibodies

paulrobinsonthyroid.com/cou...

[puddlehead7 in reply to SlowDragon]

Thankyou for your reply, you’re definitely not a slow dragon. Actually I had a private thyroid test because my Dr.felt my symptoms indicated a possible thyroid problem. But His blood test came back Negative. My results showed my TSH 2.4 MlU/L. ( Range 0.7-4.2) Free T3. -3.9pmol/L. (Range3.1- 6.8pmol/L) Free Thyroxine 16pmol/l. ( Range12-22 pmol/L)Ferritin 62ug/L. Folate 4.5 ug/L. Vit D97 nmol/L

This is all too technical for me. That’s why I’m called puddlehead. I appreciate all advice given. Thankyou.

[SlowDragon Administrator in reply to puddlehead7]

TSH 2.4 MlU/L. ( Range 0.7-4.2)

Free T3. -3.9pmol/L. (Range3.1- 6.8pmol/L)

Free Thyroxine 16pmol/l. ( Range12-22 pmol/L)

Ferritin 62ug/L.

Folate 4.5 ug/L.

Vit D97 nmol/L

So are you currently taking any thyroid medication?

Ft3 is Low at 22% through range

Ft4 40% through range

Atrial fibrillation can occur with low Ft3 or low Ft4

pubmed.ncbi.nlm.nih.gov/175...

60 patients (22.4%) had low FT3 levels (<2 pg/ml) and 24 patients (9%) had low FT4 levels (<0.9 ng/dl).

Folate is low

[puddlehead7 in reply to SlowDragon]

Thanks for your further reply. I seem from your remarks, it is likely that I don’t have a thyroid problem. Is that so? I am not taking any thyroid medication. I take beta blockers following episodes of Atrial fibrillation. 2.5mg. Thankyou very much for your information.

[tattybogle]

just so you know

< means 'less than'

> means 'more than'

[helvella Administrator Thyroid UK in reply to tattybogle]

Also included in:

helvella - Abbreviations and Acronyms

Some years ago, I started compiling a list of many of the abbreviations and acronyms that appear on the Thyroid UK forum ( healthunlocked.com/thyroiduk/ ) regularly. The idea was to make it relatively quick and easy to look up abbreviations and acronyms without being waylaid by the many irrelevant possibilities that web searches tend to return.

Currently it contains over 700 entries. I continue to update the document quite frequently!

[puddlehead7 in reply to tattybogle]

Thanks tattybogle. So can learn something new, even at 82.

[radd]

Sotired123,

< Think of a crocodile's mouth closed so he can only eat 'less than'.

> And a crocodile's mouth wide open so he can eat 'more than'.

[radd]

🤣👏👍