Change in blood results 12 wks apart (without t... - Thyroid UK

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Change in blood results 12 wks apart (without treatment)

deacster profile image
13 Replies

Hi everyone,

I wanted to post my 1st and 2nd blood results, 12 weeks apart, to gather some thoughts.

TSH 0.03 (0.27-4.2) - was 1.41

FT4 19.3 (12-22) - was 12.1

FT3 5.48 (3.1-6.8) - was 5.4

Thyroid Peroxidase Antibodies <9 (0-34) - same

Thyroglobulin Antibodies 15.1 (0-115) - was 10.7

So, T4 was borderline low with normal TSH before. Now T4 is in the upper range, although TSH is low. Is this a good thing because I'm producing more hormone or should I be concerned I'm edging towards hyper?

I had the baseline test done with Forth as well; everything else in normal range but B12 and Vit. D were at the low end.

Grateful for any thoughts :)

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deacster profile image
deacster
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13 Replies
JAmanda profile image
JAmanda

Doesn't seem to be anything wrong with your thyroid...

tattybogle profile image
tattybogle

it can be explained by this:T4 was previously a bit low .. so TSH did it's 'thing' and rose to 1.4 to encourage thyroid to make more T4/3 ... that has now happened and so FT4 level is better.. and as a consequence TSH lowers again , so now it's 0.03

This could be perfectly normal thyroid function.

fT3 stays pretty much the same because that's what the system is always trying to achieve ... stable fT3 level.. it has complex way's of achieving this and TSH (Thyroid Stimulating Hormone) made by the pituitary gland is a part of this system.

You will have to keep an eye on thyroid results over a longer period of time to see what happens next.

one result of 0.03 ( a snapshot in time ) is not anything to worry about.. it could well settle itself back at somewhere around 1 .. TSH both drives AND responds to fT4/3 levels.. there can be a bit of a lag between fT4 moving and TSH level catching up... and also a lag between TSH rising /falling and fT4 production catching up

....... it could even be that 0.03 is your 'normal' level, we are all very different and even the 'normal lab ranges only cover 97.5% of the population , so if you happen to be in the other 2.5 % ... then 0.03 could theoretically be OK for you .

SlowDragon profile image
SlowDragonAdministrator

What are your most recent vitamin results and ranges

Vitamin D, folate, ferritin and B12

What vitamin supplements are you currently taking

deacster profile image
deacster in reply to SlowDragon

Active B12 49.4 pmol (37.5+ normal)

Ferritin 26.5 ug/L (13-150)

Folate 36.3 nmol/L (8.83 - 60.8)

Vit D 55.3 nmol/L (50-175)

I take B12 and D in spray regularly as I'm vegan, but they are both lower than I would like. I have a history of Vit D deficiency and it does seem to drop quite quickly over winter. I'd got it up to about 125 previously and felt much better at that level.

I take a liquid iron supplement occasionally when I get leg cramps/spasms as it seems to relieve it.

I have a large goitre, which is my reason for checking thyroid function - trying to figure out what might be causing it to grow so much while I'm waiting months for an ENT clinic apt.

ETA ranges :)

SlowDragon profile image
SlowDragonAdministrator in reply to deacster

How long have you been vegan

Do you take a recommended vegan multivitamin too

Vegan diet is low in many essential vitamins, including possibly iodine

Iodine is a controversial supplement with thyroid issues.

So you could test first

SeasideSusie has details of the most accurate iodine test

Obviously vitamin D, Active B12 and ferritin all too low

SlowDragon profile image
SlowDragonAdministrator in reply to deacster

Low B12 symptoms

b12deficiency.info/signs-an...

With serum B12 result below 500, (Or active B12 below 70) recommended to be taking a B12 supplement as well as a B Complex (to balance all the B vitamins) initially for first 2-4 months, then once your serum B12 is over 500 (or Active B12 level has reached 70), stop the B12 and just carry on with the B Complex.

As vegan you might to need to continue both B12 and vitamin B complex, rather than just vitamin B complex

B12 sublingual lozenges

amazon.co.uk/Jarrow-Methylc...

cytoplan.co.uk/shop-by-prod...

healthunlocked.com/thyroidu...

supplementing a good quality daily vitamin B complex, one with folate in (not folic acid) may be beneficial.This can help keep all B vitamins in balance and will help improve B12 levels too

Difference between folate and folic acid

chriskresser.com/folate-vs-...

B vitamins best taken after breakfast

Igennus Super B is good quality and cheap vitamin B complex. Contains folate. Full dose is two tablets per day. Many/most people may only need one tablet per day. Certainly only start on one per day (or even half tablet per day for first couple of weeks)

Or Thorne Basic B is another option that contain folate,

IMPORTANT......If you are taking vitamin B complex, or any supplements containing biotin, remember to stop these 7 days before ALL BLOOD TESTS , as biotin can falsely affect test results

endo.confex.com/endo/2016en...

endocrinenews.endocrine.org...

SlowDragon profile image
SlowDragonAdministrator in reply to deacster

I have a large goitre, which is my reason for checking thyroid function - trying to figure out what might be causing it to grow so much

Have you seen endocrinologist

Have you explained you are vegan

endocrine-abstracts.org/ea/...

Vegan diet is the only real way for this deficiency to occur in the U.K

mayoclinic.org/diseases-con...

The most common cause of goiters worldwide is a lack of iodine in the diet. In the United States, where the use of iodized salt is common, a goiter is more often due to the over- or underproduction of thyroid hormones or to nodules in the gland itself.

deacster profile image
deacster in reply to SlowDragon

Thank you. Yes Iodine deficiency was my first thought, but it was completely dismissed by GP. I did explain I am a long term vegan, I don't buy table salt and I don't buy much processed food that might contain it either because I avoid gluten.

SlowDragon profile image
SlowDragonAdministrator in reply to deacster

But you should be taking supplements recommended for vegan diet

Recommend you do iodine Test first before starting

SlowDragon profile image
SlowDragonAdministrator in reply to deacster

markvanderpump.co.uk/blog/p...

Of course this presents a problem since these foods will not feature in a vegan diet. It is crucial, therefore, that other iodine containing foods are included for example:

Cranberries - 56g - 200 mcg

Baked Potato - one medium - 60 mcg

Haricot Beans - 64g - 32 mcg

veganfoodandliving.com/vega...

Plant foods containing iodine include wholegrains, green beans, courgettes, kale, spring greens, watercress, strawberries and organic potatoes with skin. However, amounts tend to be low and variable depending on how much iodine is in the soil.

vegansociety.com/resources/...

SeasideSusie profile image
SeasideSusieRemembering in reply to deacster

deacaster

If you are want to do an iodine test then a non-loading urine test is said to be the best test. Genova Diagnostics offer this test.

thyroiduk.org/help-and-supp...

deacster profile image
deacster in reply to SeasideSusie

Oh thanks so much, I had not been able to find a test for this 👍

SeasideSusie profile image
SeasideSusieRemembering in reply to deacster

I've just checked, it's END25

Urine Iodine Test:

Specimen requirements: Urine

Cost: £71.00Order Code: END25

Turnaround time: 5 - 10 days

Iodine is an essential trace element, vital for healthy thyroid function. Adequate levels are required to enable the production of T3 and T4 thyroid hormones, whilst also being required in other areas of health. Deficiencies can lead to impaired heat and energy production, mental function and slow metabolism. Urine iodine is one of the best measures of iodine status. This test is not performed as a loading test, but can be used to establish existing levels or to monitor iodine supplementation.

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