Blood results based on Levo 110 and liothyronin... - Thyroid UK

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Blood results based on Levo 110 and liothyronine 40 mg

edleenia profile image
16 Replies

Today I got blood results while taking Levothyroxine 110 mg and Liothyronine 40 mg and these are my results.

TSH 3rd generation. : 0.051 (low) range: 0.34-4.4

T3, total 102 Range:87-178

T4,Total. 6.91 Range: 6.1-12.2

Free T3 2.6 Range: 2.3-4.2

Free T4 0.55 (low) Range: 0.61-1.12

TSI <80. Range: <140

Cortisol. 8.9 Range 5.0-25

CRP. 8.5 (h) Range: 0.0-3.0

Can anyone make a suggestion. I still have joint pain, foggy brain, hard concentration

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edleenia
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16 Replies
SlowDragon profile image
SlowDragonAdministrator

When were vitamin D, folate, ferritin and B12 last tested

What vitamin supplements are you currently taking

Are you on strictly gluten free diet or dairy free diet

Considering how much levothyroxine and T3 you are taking you are likely looking at poor gut absorption and low vitamins

edleenia profile image
edleenia in reply toSlowDragon

Thanks doc has lowered my t3 from 40mg to 30mg . I’m so confused

edleenia profile image
edleenia in reply toSlowDragon

So my new meds are 110 of T4 and 30 mg of T3

SlowDragon profile image
SlowDragonAdministrator

Recommended on here that all thyroid blood tests should ideally be done as early as possible in morning and before eating or drinking anything other than water .

Last dose of Levothyroxine 24 hours prior to blood test. (taking delayed dose immediately after blood draw).

This gives highest TSH, lowest FT4 and most consistent results. (Patient to patient tip)

If/when also on T3, make sure to take last third or quarter of daily dose 8-12 hours prior to test, even if this means adjusting time or splitting of dose day before test

Is this how you do your tests?

edleenia profile image
edleenia in reply toSlowDragon

Thank you very much

SlowDragon profile image
SlowDragonAdministrator in reply toedleenia

Trying liquid levothyroxine can help improve absorption

Gett Vitamins tested and optimal absolutely essential

JAmanda profile image
JAmanda

Your T3 and t4 are really low in range. Does the Endo think you could take more meds? I'd take them all first thing and leave a good hour or more before eating. And leave off caffeine and calcium for several hours just to try to give the meds the best chance to absorb. Plus optimise vits etc as suggested already.

edleenia profile image
edleenia in reply toJAmanda

Hi well he thought I was taking too much t3 so he lowered from 40 to 30 mg. I’m so confused

DippyDame profile image
DippyDame

Your FT4 has dropped off the range, your 40mcg dose of T3 could partly account for that but your FT3 still remains at the bottom of it's range which suggested undermedication of both or either hormone.

Did you compare FT4 with FT3 when on levo only to check your conversion of T4 the storage hormone to T3 the active hormone? T3 is essential to every cell in the body..... a regular and adequate supply is vital for good health.

High FT4 with low FT3 indicates poor conversion and the need for added T3.

Are you taking T3 because of poor conversion or just in case it might help!

Have you optimised nutrients as advised?

110mcg levo doesn't appear to be enough, can you increase to 125mcg in the first instance and see how you feel. It's only a small increase but let that settle then retest and adjust further to raise FT4 and FT3 to close to 75% through their ref ranges....and to feel better

On the other hand if conversion is known to be good then raise levo to 125mcg and reduce the T3 a little.

It really is a case of trial and error at this stage.

edleenia profile image
edleenia in reply toDippyDame

Hi thanks my doctor has lowered mg t3 from 40 mg to 30

Batty1 profile image
Batty1 in reply toedleenia

Your doctor is lowing your T3 meds from 40 mg to 30 mg because of your TSH and for no other reason .... this is how Endos and GPs do thing and the above poster are right you probably need more meds not less but because they doctors treat by the TSH its next to impossible to get on the correct thyroid dose, you gotta speak up and refuse the reduction and demand the increase and explain your reasons for wanting the increase.

DippyDame profile image
DippyDame in reply toedleenia

Not surprised that you are confused

Did s/he explain why?

I'd suggest not good enough, they need to address your seriously low FT4 and FT3 too.....both low for your dose of hormones

Meantime consider asking your GP to give you a trial of increased levo dose.....more likely to get a result than just asking outright!! Say you are very concerned about your low FT4 given your hypo symptoms - tick yours off the list below and show it to GP

thyroiduk.org/signs-symptom...

Your state of conversion most likely holds the key, along with your levels of vit D vit B12, folate and ferritin which should be optimal for good thyroid health.

If your conversion IS good, then I would be increasing levo up to say 150mcg and dropping T3....but we don't have that info! So, it's trial and error....and testing.

S/He will probably waffle on about suppressed TSH....it doesn't matter! 40mcg lio will automatically lower TSH. TSH is a pituitary hormone not a thyroid hormone......basically it responds to hormone levels and sends a signal to the thyroid to produce more, or less, hormone.

High CRP indicates inflammation. Have you been ill, other than hypo? This may be causing poor absorption from gut to serum hence low FTs. Have they mentioned investigating causes of this eg colitis, RA

Do you have Hashimoto's? If so a gluten free diet often helps.

Hopefully your doc learns more about thyroid treatment and will investigate further. Come back with any questions you have and members will advise.

Best...

DD

edleenia profile image
edleenia in reply toDippyDame

Thank you so much

AndiRiley profile image
AndiRiley

You certainly don't need a reduction in dose. You are taking a decent amount of medication, but it's not getting into your blood - poor gut absorption or possibly you are consuming other foods or supplements that are absorbing the medication before it gets a chance to enter your system?

When do you eat / supplement in relation to medication doses?

edleenia profile image
edleenia in reply toAndiRiley

Hi , so why I’m I still feeling horrible? Still shaky at times, slight panic attacks, hard focusing etc.

DippyDame profile image
DippyDame in reply toedleenia

If the hormones don't reach the blood, from the gut for whatever reason, ( suggestions been given here by others) then they are not available to be "grabbed" by the T3 receptors which take them from the serum to the trillions of cells in the body where they do the job of keeping us healthy......put very basically!!!

In other words, although you are swallowing the hormones they never reach their intended destination where they would help you

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