perodidase

[bluehayes]

good morning I have had a thyroid test through medicheck as feeling lousy I do have pernicious anaemia and have b12 injections every 12 weeks my last blood test with drs showed my haemoglobin was below range red blood sells below range and my mchc below range my medichecks came back tsh 2.82 free t3 4.74 and free thyroxine 14.8 which is in normal range but my thyroglobulin came back elevated 334 and mythyroid peroxidase antibodies at125 what I would like to know would I need treatment for this sorry for long post all new to me many thanks

[bluehayes]

Thankyou janey no I have.nt I Did a private blood test and only just got the results back .y Drs are.nt very sympathetic so I wonder if it's worth seeing them with my results if they are.nt to high

[greygoose]

What were the ranges for all these tests? We always need to have the ranges because they vary from lab to lab.

Your high antibodies are suggesting Hashi's, but there is no treatment for Hashi's. All we can do is replace the thyroid hormones when we become hypo - as you surely will, but you're not there yet. But doctors tend to ignore antibodies, anyway, so no point in seeing a doctor about them. Just keep testing.

As you have Pernicious Anemia, it's no real surprise that you also have Hashi's, I'm afraid.

[bluehayes in reply to greygoose]

hi grey goose thankyou for your message my tsh is 2.82 miu/l (0.27-4.2) my free t3 is 4.74 pmo1/l (3.1-6.8) free thyroxine 14.8 pmo1/l(12-22 my thyroglobulin antibodies is 334 <115ku/l and thyroid peroxidose is 125 <34 kiu/l hope you understand these cause I don't x

[greygoose in reply to bluehayes]

Yes, I do.

As I said, you have Hashi's, as indicated by the high antibodies.

And, your TSH says that your thyroid is struggling, but your FT4 and FT3 say that you're not quite hypo yet, although you probably will do sometime in the future.

Whether or not you would benefit from thyroid hormone replacement at this point is debatable. But, the hard fact is that you're not likely to get it until your TSH goes at least over-range, if not higher. But, as I said, there's nothing anyone can do for the Hashi's/antibodies themselves.

[bluehayes in reply to greygoose]

Thankyou again for your reply and knowledge I will mention it next time I go docs as I feel awful even after my b12 injection

[greygoose in reply to bluehayes]

You're welcome. Good luck.

[SlowDragon Administrator]

High TPO antibodies confirms you have Hashimoto's also called autoimmune thyroid disease

Ask GP to test folate, ferritin and vitamin D

These are often too low with autoimmune thyroid disease

Improving low vitamin levels can help improve symptoms and conversion of FT4 to FT3

For full Thyroid evaluation you need TSH, FT4 and FT3 plus both TPO and TG thyroid antibodies tested. Also extremely important to test vitamin D, folate, ferritin and B12

Low vitamin levels are extremely common, especially if Thyroid antibodies are raised

Recommended on here that all thyroid blood tests should ideally be done as early as possible in morning and fasting. This gives highest TSH, lowest FT4 and most consistent results. (Patient to patient tip, best not mentioned to GP or phlebotomist)

Hashimoto's very often affects the gut and leads to low stomach acid and then low vitamin levels

Low vitamin levels may affect Thyroid hormone working

Poor gut function can lead leaky gut (literally holes in gut wall) this can cause food intolerances. Most common by far is gluten. Dairy is second most common.

According to Izabella Wentz the Thyroid Pharmacist approx 5% with Hashimoto's are coeliac, but over 80% find gluten free diet helps, sometimes significantly. Either due to direct gluten intolerance (no test available) or due to leaky gut and gluten causing molecular mimicry (see Amy Myers link)

Changing to a strictly gluten free diet may help reduce symptoms, help gut heal and slowly lower TPO antibodies

While still eating high gluten diet ask GP for coeliac blood test first or buy test online for under £20, just to rule it out first

Assuming test is negative you can immediately go on strictly gluten free diet




(If test is positive you will need to remain on high gluten diet until endoscopy, maximum 6 weeks wait officially)




Trying gluten free diet for 3-6 months. If no noticeable improvement then reintroduce gluten and see if symptoms get worse

chriskresser.com/the-gluten...

amymyersmd.com/2018/04/3-re...

thyroidpharmacist.com/artic...

scdlifestyle.com/2014/08/th...

drknews.com/changing-your-d...

restartmed.com/hashimotos-g...

healthcentral.com/article/t...

Other gut issues due to being hypothyroid

healthunlocked.com/thyroidu...

[Angel_of_the_North]

Cannot really comment on results without ranges, but high TG and TPO antibodies means autoimmune thyroid disease, but NHS will not treat until free T4 is under range and TSH is over, or TSH is over 10.

[Hidden]

As greygoose mentioned when ferritin levels are low in the blood which is found stored in the liver as hepatocytes, the body will signal to release ferritin, which binds to a transporter called transferrin. This protein combines to transport it to where blood cells are made. If a person does not have enough ferritin, iron stores can deplete quickly. Without enough iron your red blood cells won't be able to transport oxygen to the red cells. If you are anaemic it may be caused by not enoughb12 to make new blood cells. Poor digestion may lead to lack of absorption of vitamin B12. Too little gastric acid can enable anaemia from vitamin B12 deficiency. Enzymes to break down protein can help the stomach restore a proper PH of gastric juices.

Info is from Body Ecology Are you anemic? Going Beyond Iron supplements. In addition to fat soluble vitamin D is vitamin K found in beef,pork duck goose and chicken livers. K2 Other good sources of vitamin K are parsley and kiwi fruit K1.

VitaminK.com gives information how vitamin K2 helps marrow cells produce red blood cells, white blood cells and platelets. Vitamin E is a source of providing red blood cells and can be found in sunflower seeds peanut butter, avocados olive oil and whole grains. As you may have Hashis - you might have to watch all grains which mainly contain gluten including flour rye barley/malt rice, spelt, even oats unless they are a special strain. Even if you are not gluten intolerant it is possible to be grain intolerant which is misleading if you are told you are not gluten intolerant. I had food tests privately, through a chemist chain from a quick smart test taking minutes and an hour to interpret which was brill. It showed just this and when I removed the grains, felt much better.