hs Crp results high: I'm attaching some results... - Thyroid UK

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hs Crp results high

Angelawimbledon profile image
14 Replies

I'm attaching some results. I'm on T3 and some T4 and at my best for a long time. I treated myself to a broader set of tests and am shocked particularly by the above test results. (My tsh has gone a little low but I see my Endo next week and will probably tweak again.)

It's a marker for inflammation to a point but even with Hashi's is it high? Would we expect a high result anyway? I've just lost a stone and this test has motivated me in a big way.

Scary?

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Angelawimbledon profile image
Angelawimbledon
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14 Replies
ShootingStars profile image
ShootingStars

Hi Angelawimbledon. CRP is just one of several inflammatory markers, and is not specific to any condition. Is this the first time you've tested CRP? Your's is barely over range. Not scary. It could be this way for many reasons. Could be from an infection, autoimmune disease such as Hashi's or another condition, bowel problems, injury, or other causes. Have you been sick, had bowel problem, an injury or have any other known health problems? What are your current symptoms?

Remember, medication is not dosed based on TSH levels. Your current levels are not optimal, even though your are taking T3 and T4. If you lower your medication just to increase TSH, your FT3 will go even lower, as will your FT4. Symptoms will increase. Your TPO is barely high. Less medication might increase your antibodies, too.

Some people with Hashi's test positive for inflammatory markers, some do not. I am one of the later. My TPO is thru the roof at the moment (many thousands high, not a typo). My inflammatory markers have always been low, even before I started treatment (t3 and t4) and my face was a bit puffy. Years later after and after my levels were optimal, I had inflammation going one in my joints but mainly my hands. My inflam markers were still low, within range. I definitely had inflammation. It just didn't show up on the standard group of inflam markers that I tested.

If you retest CRP down the road and it has increased, it will take some effort to find the cause. If you thyroid levels drop lower, this could be why. If your TPO increases, could also be the cause, or other causes.

researcherUK profile image
researcherUK

CRP is an inflammation marker. It ought to be near zero.

If you are not on a gluten-free diet, and noting that you have some antibodies and low B12 this could point towards either gluten sensitivity or perhaps it is also worth asking the endo to test you for celiac's and pernicious anemia, too.

Undigested gluten remains in the guts and causes inflammation. It also inhibits the absorption of some vitamins and minerals.

Your ferritin is high for someone with Hashimoto's unless you are supplementing with iron this could be another marker for inflammation. If you are supplementing with iron, perhaps you need to consider reducing the dose and going on a maintenance dose.

Do you take any Vit D? Your levels are on the low side.

You are on the right track!

All caught in time!

T3sortedme profile image
T3sortedme

Your TSH is OK and probably where it needs to be for you to be well. The T3 is mid range and you want it there or higher. Because you are on T3 your T4 is low which is what you would expect. If you are well, as you indicate, I would not change the T3/T4 dosing.

Raoudha profile image
Raoudha

Hey

My CRP is high place thyroïdites I have heart inflammation

annegal profile image
annegal

Your TSH 0.01 is that OK.? Mine is 0.02 and I am worried there are issues that may arise from this and I am avoiding contact with my GP because I don’t know what to say. What will you say to your GP if they suggest a change in dose subject to that result??

Phoenix605 profile image
Phoenix605 in reply toannegal

The GP will probably spout heart and osteoporosis risk due to suppressed TSH. However, there is research which proves that it is only a risk if the suppression is CAUSED by high FT3. It is the excess T3 production in hyperthyroidism that causes these risks not the suppressed TSH itself. Many hypos find their TSH suppresses despite clearly mid range FT3, medics dont seem to grasp that the feedback loop often doesn't work properly when there is thyroid dysfunction. I asked GP to produce evidence of the risk or a high FT result or I was not willing to decrease, he couldnt so I refused (and found another GP)

My latest results from a couple of days ago are a case in point (I am on NDT) I am suppressed but actually need an increase

TSH - 0.05

FT4 - 10.2 (12-22)

FT3 - 4 (3.1-6.8)

Cant find the original link but this one may help

discovery.dundee.ac.uk/port...

annegal profile image
annegal in reply toPhoenix605

That’s really helpful. I posted my own results last week for advice but there were no replies so I decided just not to have another blood test as I was told to by the GP to. Because I feel ok on my dose.

ShootingStars profile image
ShootingStars in reply toannegal

Hi annegal. She has Hashi's. With Hashi's the TSH should be suppressed, but most importantly, FT3 and FT4 should be in the optimal area of the range. The problem with lowering dosage for Angelawimbledon is that neither her FT3 nor FT4 are optimal yet and she has hypo symptoms. Lowering dosage will lower her thyroid hormones and increase her hypo symptoms. If FT3 and 4 were already optimal, decreasing med dosage a little wouldn't be a problem.

annegal profile image
annegal in reply toShootingStars

Sorry - I don’t want to jump onto someone else’s thread - could you have a look at my post and help me with my results. Thank you

ShootingStars profile image
ShootingStars in reply toannegal

Hi annegal. I just did.

:-)

loueldhen profile image
loueldhen

Your results look fine. Important thing is what you feel like. <=0.03 tsh is considered to be ‘suppressed’. Endo might want to reduce meds a tad. CRP floats all over the place in my experience and I certainly wouldn’t worry about 5.02. Suggestions about diet etc good. Antibodies well under control. Typically can float about in hundreds and thousands yours look good!

endomad profile image
endomad

I wouldnt worry about your CRP test, mine is similar, just over and someone put the fear of god into me saying it was very serious etc but apparently if you have a common cold it would be well over a 100 and a cold isnt going to kill you. My dr was very concerned how upset i was and spent half an hour explaining it all to me. A sore muscle, cold, lack of sleep everything shows up on CRP any inflammation at all, if worried you can do anti inflammation diet. He did say the homocystene (spelling?) a better marker for dangerous inflammation or heart issues but obvs nhs dont do them x

SlowDragon profile image
SlowDragonAdministrator

Your vitamin D and B12 are both low.

Better You vitamin D mouth spray is good as avoids poor gut function of Hashimoto's. Aiming to improve to around 100nmol. Testing twice yearly via vitamindtest.org.uk £29 postal kit

A good quality vitamin B complex might be beneficial

Hashimoto's affects the gut and leads to low stomach acid and then low vitamin levels

Low vitamin levels affect Thyroid hormone working

Poor gut function can lead leaky gut (literally holes in gut wall) this can cause food intolerances. Most common by far is gluten.

According to Izabella Wentz the Thyroid Pharmacist approx 5% with Hashimoto's are coeliac, but over 80% find gluten free diet helps significantly. Either due to direct gluten intolerance (no test available) or due to leaky gut and gluten causing molecular mimicry (see Amy Myers link)

Changing to a strictly gluten free diet may help reduce symptoms, help gut heal and slowly lower TPO antibodies

Ideally ask GP for coeliac blood test first

amymyersmd.com/2017/02/3-im...

chriskresser.com/the-gluten...

thyroidpharmacist.com/artic...

scdlifestyle.com/2014/08/th...

drknews.com/changing-your-d...

thyroidpharmacist.com/artic...

Angelawimbledon profile image
Angelawimbledon

Thank you all. I'm one of the luckier ones as GP goes along with Endo. My 2nd Endo. Couldn't put in print what I think about the first but my GP knows. I'm paying for Endo but could see on NHS. I'll prob change when feeling my best. After I lose another 3-4 stone...

I've started Solgar Vit D drops. Slipped up taking supplements as sometimes didn't feel like large tablets.

Thanks again

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