I had a total thyroidectomy a few years ago. Over the past year I've had a lot of dose changes as GP basically can't work out what is wrong with me. I was put up to 150mg before Xmas due to high tsh, 3 weeks later put down to 100mg because I'd become very hyperthyroid. That was 6 weeks ago and I'm STILL really unwell. I vomit everyday, I'm exhausted to the point i fainted after walking half a mile. My last blood test showed my t4 and tsh were BOTH high (tsh was 4.8, t4 was 21). Endo is testing for addisons and pituitary issue but won't check other thyroid levels (t3, reverse t3 etc). Obviously I need to wait for cortisol/pituitary results but I'm feeling really down and upset as well as really unwell. Has anyone else ever had any results like this?