Advice appreciated: Hi, I wonder if I could get... - Thyroid UK

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Advice appreciated

NiaJones profile image
4 Replies

Hi, I wonder if I could get some comments on some private blood results. My GP is refusing to run any further tests on me and has effectively told me that some people have to live with not knowing what’s wrong with them (sigh):

TSH 3.04 (0.27 – 4.2)

FT4 19.3 (12.0 22.0)

T4 101 (59 – 154)

FT3 3.3 (3.1 – 6.8)

With negative antibodies, RT3 not tested.

I’ve had a large thyroid cyst aspirated twice this year, but no plan for treatment. I also have a goitre which has only started to grow this year.

CRP is 13.4 (<5.0) and has been elevated since at least the beginning of this year. The glands under my chin have been swollen for at least 4 months and I generally feel pretty rubbish. I’ve had low ferritin levels for a number of years (around 10), but this has corrected itself since I’ve been treated for B12 deficiency.

B12 >1476 (140 - 724)

Folate 19.98 (2.91 – 50.0)

Vit D 90 (50.0 - 200.0)

Cortisol 501 (133.0 – 537.0)

Ferritin 144 (13.0 – 150.0)

Creatine kinase 470 (26.0 – 140) I’m struggling with aching muscles all over, particularly my legs, don’t do any strenuous exercise at the gym, although I walk my dogs regularly.

I’ve got enlarged adrenals with thickening of the left adrenal, but haven’t been diagnosed with an adrenal problem (long story, don’t really want to go there right now) I’m currently also waiting on private blood results to look at my neuroendocrine pancreatic function, which I’m expecting in the next couple of days. I’ve been trying, without success, to lose weight of a couple of years and this year my hair has started to fall out big time, plus numerous other symptoms.

I’ve got a reasonably good diet (but by no means perfect), don’t drink or smoke. Any input/ thoughts would be appreciated - thanks

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NiaJones
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4 Replies
marsaday profile image
marsaday

Well you have plenty of thyroid in the tank (Ft4) but we run on T3, so the T4 has to be converted by the body into T3. This is where you fall down as you have very low levels of T3.

It looks like a conversion issue and because conversion mostly takes place in the liver this is an area to look into. Selenium is a good supplement for conversion issues, or some brazil nuts daily.

Women tend to have bigger problems than men due to higher oestrogen levels. The oestrogen clogs up the liver somehow and slows down conversion. This is very simplistic, but some areas to look at are:

Conversion of T3

Estrogen dominance

Fatty / unhealthy liver issues.

When doctors say what yours has said, it shows you he doesn't have the time to get to the bottom of your health issues. You are ill for a reason and the best person to solve it will be you thanks to forums like this. We can share our imperfect knowledge, but you will be the one to follow up leads etc. I am sure you can get to the bottom of things, but it may take some time.

Nanaedake profile image
Nanaedake

Which antibodies were tested? How were you treated for B12 deficiency and are you still receiving treatment?

You have a high creatine kinase level according to the results you've given and CRP is raised so you have inflamation somewhere. It does seem like there are a few clues that need following up.

Could you take these results to your GP and ask him whether kidney function needs to be checked or whether there's an obvious reason for the raised creatine kinase? Hypothyroidism can cause a raised level but your TSH is not elevated outside of the lab range although FT3 is low and so I wonder if it's caused by something else?

Do you know what your eGFR level is?

ITYFIALMCTT profile image
ITYFIALMCTT

Just to second the others - what is your GP's explanation for the CK result?

I'm assuming you've had all the standard auto-immune tests like ANA,

labtestsonline.org.uk/under...

Your calcium and PTH were measured to rule out hypoparathyroidism?

SlowDragon profile image
SlowDragonAdministrator

The fact you have a goitre strongly suggests thyroid is struggling. TSH is on high side and FT3 low. Saliva glands swollen also indicative

You need an adrenal and thyroid specialist endocrinologist

Email Louise at a Thyroid UK for list of recommended thyroid specialists louise.roberts@thyroiduk.org.uk

If you have adrenal issues this could be because adrenals are having to work harder to compensate for low thyroid and then low or high cortisol can badly affect conversion of T4 to T3

You could do adrenal stress test

thyroiduk.org.uk/tuk/testin...

And possibly DIO2 gene test

thyroiduk.org.uk/tuk/testin...

Reverse T3 test might be revealing

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