Antibodies etc

[Pink25]

Hi I don't think I have Hashimotos.

TPO antibody 308.5 (<34)

TG antibody 279.3 (<115)

Other results

Ferritin 21 (30 - 400)

Folate 1.8 (2.5 - 19.5)

B12 168 (180 - 900)

Vit D 23.9

Thanks

[greygoose]

You most certainly do!

You also have exceedingly low nutrients. What has your doctor said about these results.

[Pink25 in reply to greygoose]

Thanks GP has only prescribed me 800iu D3 but nothing for the others

[greygoose in reply to Pink25]

And 800iu is not going to do anything to help.

I suggest your read through SeasideSusie's responses to others in the same position, to see how much of what she advises people to take to raise their levels.

[Puska]

Where is is described as <34, that means below that number is normal. Your levels are way above hence hashimotos.

[SlowDragon Administrator]

Your antibodies are high this is Hashimoto's, (also known mainly by UK medics as autoimmune thyroid disease).

About 90% of hypothyroidism in UK is due to Hashimoto's.

Hashimoto's very often affects the gut, leading to low stomach acid, malabsorption causing low vitamin levels and leaky gut.

Low vitamins that affect thyroid are vitamin D, folate, ferritin and B12. When they are too low they stop Thyroid hormones working.

Yours are extremely low

See SeasideSusie detailed vitamin advice eg

healthunlocked.com/thyroidu...

Your B12and folate are extremely low

Suggest you post on PAS Unlocked too for B12 advice. You almost certainly need to be tested for Pernicious Anaemia and intrinsic factor before starting B12 injections

healthunlocked.com/pasoc

According to Izabella Wentz the Thyroid Pharmacist approx 5% with Hashimoto's are coeliac, but over 80% find gluten free diet helps significantly. Either due to direct gluten intolerance (no test available) or due to leaky gut and gluten causing molecular mimicry (see Amy Myers link)

But don't be surprised that GP or endo never mention gut, gluten or low vitamins. Hashimoto's is very poorly understood

Changing to a strictly gluten free diet may help reduce symptoms.

thyroidpharmacist.com/artic...

thyroidpharmacist.com/artic...

amymyersmd.com/2017/02/3-im...

chriskresser.com/the-gluten...

scdlifestyle.com/2014/08/th...

drknews.com/changing-your-d...

Low stomach acid can be an issue

Lots of posts on here about how to improve with Apple cider vinegar or Betaine HCL

thyroidpharmacist.com/artic...

Other things to help heal gut lining

Bone broth

thyroidpharmacist.com/artic...

Probiotics

carolinasthyroidinstitute.c...

hypothyroidmom.com/hashimot...

Great film definitely shows why just testing TSH is inadequate

drbradshook.com/understandi...

What are your TSH, FT4 and FT3? I guess you are under medicated to have vitamin results so bad. Or have you recently had dose reduced?

Just seen your other post, you are under medicated. Ask GP for 25mcg dose increase, plus dealing with low vitamins

Your TSH should be lower, around one and FT4 towards top of range

You might want to consider seeing a different GP

[CaroleM-A]

I agree with all the other comments and would just add that when you do start on B12injections your GP should give you a 1ml injection every other day for two weeks and then monthly as a maintenance dose. Many just go straight to the maintenance dose which doesn’t tackle the low level

[SeasideSusie Remembering]

Pink25 I am assuming that your GP has done nothing about these dire levels or you would surely have mentioned what further tests have been carried out and what has been prescribed.

Ferritin 21 (30 - 400)

For thyroid hormone to work (that's our own as well as replacement hormone) ferritin needs to be at least 70, preferably half way through range. As yours is under range ideally you need an iron infusion so ask for one, that will raise your level within 24-48 hours, tablets will take many months.

You can also help raise your level by eating liver regularly, maximum 200g per week due to it's high Vit A content, and including lots of iron rich foods in your diet apjcn.nhri.org.tw/server/in...

Also, you need a full blood count and iron panel to see if you have anaemia so ask for those too. If your MCV is low with MCHC over range then that suggests iron deficiency anaemia which will need treating with 2 or 3 x ferrous fumarate daily. Take each iron tablet with 1000mg Vitamin C to aid absorption and help prevent constipaton. Always take iron 4 hours away from thyroid meds and two hours away from other medication and supplements as it will affect absorption.

**

Folate 1.8 (2.5 - 19.5) B12 168 (180 - 900)

You absolutely must go straight over to the Pernicious Anaemia Society for further advice. These results are seriously low, you are folate and B12 deficient, further investigations need to take place, so whatever they advise discuss with your GP healthunlocked.com/pasoc (Most people ignore the advice to post on the PA forum, if you choose to do that then it would be rather foolish.)

Check for signs of B12 deficiency here b12deficiency.info/signs-an... and mention these in your post on the PA forum along with these results plus your ferritin result and any results you may already have from iron panel/full blood count.

**

Vit D 23.9

I am assuming that the unit of measurement is nmol/L. If so then you are seriously deficient. Please can you confirm that this is the unit of measurement.

[Pink25 in reply to SeasideSusie]

nmol/l for vitamin D

[SeasideSusie Remembering in reply to Pink25]

OK, so

Vit D 23.9nmol/L

This is severely deficient and you need loading doses of D3, don't accept 800iu (that is a very low maintenance dose), it must be loading doses - see NICE treatment summary for Vit D deficiency:

cks.nice.org.uk/vitamin-d-d...

"Treat for Vitamin D deficiency if serum 25-hydroxyvitamin D (25[OH]D) levels are less than 30 nmol/L.

For the treatment of vitamin D deficiency, the recommended treatment is based on fixed loading doses of vitamin D (up to a total of about 300,000 international units [IU] given either as weekly or daily split doses, followed by lifelong maintenace treatment of about 800 IU a day. Higher doses of up to 2000IU a day, occasionally up to 4000 IU a day, may be used for certain groups of people, for example those with malabsorption disorders. Several treatment regims are available, including 50,000 IU once a week for 6 weeks (300,000 IU in total), 20,000 IU twice a week for 7 weeks (280,000 IU in total), or 4000 IU daily for 10 weeks (280,000 IU in total)."

Each Health Authority has their own guidelines but they will be very similar. Go and see your GP and ask that he treats you according to the guidelines and prescribes the loading doses. Once these have been completed you will need a reduced amount (more than 800iu so post your new result as the time for members to suggest a dose) to bring your level up to what's recommended by the Vit D Council - which is 100-150nmol/L - and then you'll need a maintenance dose which may be 2000iu daily, it's trial and error so it's recommended to retest once or twice a year to keep within the recommended range. You can do this with a private fingerprick blood spot test with City Assays vitamindtest.org.uk

There are important cofactors needed when taking D3

vitamindcouncil.org/about-v...

D3 aids absorption of calcium from food and K2-MK7 directs the calcium to bones and teeth where it is needed and away from arteries and soft tissues where it can be deposited and cause problems.

D3 and K2 are fat soluble so should be taken with the fattiest meal of the day, D3 four hours away from thyroid meds.

Magnesium helps D3 to work and comes in different forms, check to see which would suit you best and as it's calming it's best taken in the evening, four hours away from thyroid meds

naturalnews.com/046401_magn...

Check out the other cofactors too.

**

If your GP has actually ignored these results and done nothing about them, I suggest you see a different GP, get treatment sorted, then give serious consideration to making a formal complaint for negligence against this GP.