I wonder if anyone can advise me? I was diagnosed with hypothyroidism 10 yrs ago & was prescribed Levothyroxine (50mcg) which I took without any problems until about 2/3 years ago .I started to feel unwell & thinking I needed more increased the dose which made the whole thing worse so I dropped it back down to 25mcg, felt better for a year but the same problem occurred the following yr so I came off it altogether & still felt crap. GP referred me to a well known hospital in Birmingham & they did absolutely nothing. I don't have many results to post but the last blood test said TSH 6.13 & positive TPO antibodies. Little was mentioned about T3 or 4.They discharged me & for a while I felt better but have become poorly again recently. I just don't know what to do I'm fatigued, unable to lose weight (gained a stone ) feel hungover most mornings like I've been drinking but don't really ever touch the stuff! Cold intolerant have joint pain & headaches blah blah. I do however sometimes feel better later in the day but not for long. I tried taking thyroxine again & it made me feel absolutely terrible, so no relief there. I can't get in to see my Dr so stuck really. There is so much information available & I'm so confused that I really don't know what to do. Can anyone suggest anything?