Should PAS and TUK merge, I ask?
Indian J Clin Biochem. 2015 Apr;30(2):217-20. doi: 10.1007/s12291-014-0418-4. Epub 2014 Feb 6.
Evaluation of serum vitamin B12 levels and its correlation with anti-thyroperoxidase antibody in patients with autoimmune thyroid disorders.
Jaya Kumari S1, Bantwal G2, Devanath A1, Aiyyar V2, Patil M2.
Vitamin B12 deficiency has been reported in patients with Autoimmune thyroid disorders. However there is limited data on exact prevalence of low B12 and its correlation with anti-thyroperoxidase antibody (anti-TPO) levels in these patients. The aim of our study was to estimate serum vitamin B12 levels in autoimmune thyroid disorders and to correlate B12 levels with anti-TPO. 350 patients were selected by convenient sampling. Vitamin B12 levels and thyroid parameters were estimated using fully automated chemiluminescence method on Access 2. Results of our study shows that using the manufacturer's cut-off of 145 pg/mL, the prevalence of low serum vitamin B12 was found to be 45.50 %. Higher prevalence (55 %) was seen based on the published cut-off of 200 pg/mL The study however did not demonstrate any significant correlation between vitamin B12 levels and anti-TPO (r = -0.11 and p value of 0.30).
Anti-thyroperoxidase (anti-TPO); Auto antibodies; Autoimmune thyroid disorders (AITD); Autoimmunity; Vitamin B12