What do you swallow your levothyroxine with?

For me it used to be a few sips of water, until I found out you are supposed to drink a glass of water, and that vitamin c is meant to aid absorption. Now I dissolve an effervescent vitamin c tablet (boots brand) but is that the best method?

Just this week I found out about lipsomal vitamin c, and I've also been reading that some people drink water containing lemon juice or apple cider vinegar. Now I don't know what to use!

What is the best method?

7 Replies

  • The Boots Vitamin C I just found has the following ingredients:

    Sodium Ascorbate, Sweeteners (Sorbitol, Sucralose), Ascrobic Acid, Calcium Carbonate, Maltodextrin, Magnesium Stearate, Hydroxypropyl Methylcellulose, Maize Starch, Natural Flavouring, Modified Maize Starch.


    Are they the ones you are using?

    If so, I would point out that the calcium carbonate might not be a very good idea as many calcium salts bind to levothyroxine and inhibit absorption. I would not be too sure about interactions between levothyroxine and Sorbitol, Maltodextrin, Hydroxypropyl Methylcellulose, Maize Starch, Natural Flavouring, and Modified Maize Starch. I am well aware that some of these are used in some levothyroxine tablets, but that is not sufficient to demonstrate that the precise forms used in the Boots Vitamin C do not interfere with absorption. And, for all their faults, the actual commercial tablets have at least had some testing in this direction whereas you are trying the "suck it and see" approach.

    (The removal of Teva levothyroxine from the market last year seems to have been due to a change in the ingredients which affected how well it could be absorbed. The suspicious ingredient appeared to be dextrin which might have been to a very slightly different specification.)

    Yes - I too saw some claims about vitamin C assisting absorption. If I were to go down that route, I would use a small amount of pure vitamin C powder. That would avoid the possibility of anything else causing problems.

    As it is, I have a glass of water. After all, if the manufacturers ever do any testing, it will almost certainly be by following their own recommendation of taking with water.


  • Couldn't agree more Rod - I'm a water only girl myself and would never take my levo with anything added.

    Moggie x

  • Awww, no. I can't believe I didn't check the ingredients!! My TSH results have been better, but that's probably a cumulative effect, I've been trying several things. Well I'm glad I posted! I'll stop doing that.

  • Actually, I only just checked the ingredients on mine (you'll have to excuse me, zombie brain. Things get done, but slowly!)

    They are these boots.com/en/Boots-Pharmace... Citric Acid, Sodium Bicarbonate, Ascorbic Acid, Maltodextrin, Sweeteners (Sodium Cyclamate, Sodium Saccharin), Flavour (Natural Orange Flavour), Colours (Beetroot Red, Riboflavin 5 Phosphate Sodium), Saccharose Monopalmitate. They don't contain any kind of calcium. I wonder if these ones are okay?

    There is a lot of anecdotal evidence about people feeling better when they take their meds with vitamin c. I'll leave it for now, just to be safe, but do more reading on it.

  • If you feel like you want to keep taking your levo with VitC try this one.


    Moggie x

  • I don't take them with anything. They are small enough swallow without a drink. But if you need to take them with a drink I would stick to plain water.

  • I was told that you should drink your thyroxine with a full glass of water, that if it starts to dissolve before it reaches your stomach it won't work as effectively?

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