Can vitamin C be taken with Levothyroxine? - Thyroid UK

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Can vitamin C be taken with Levothyroxine?

TooManyTablets profile image
18 Replies

I've been researching if there's anything to increase absorption of Levothyroxine, just out of curiosity, and a few articles have recommended taking vitamin C with it.Here's one I found:

palomahealth.com/learn/vita...

"Low stomach acid, also known as hypochlorhydria, is a common issue in people with hypothyroidism and autoimmune Hashimoto’s thyroiditis. The thyroid hormones play a crucial role in regulating the production of hydrochloric acid (HCl) in the stomach. When thyroid hormone levels are low, as in hypothyroidism, it can lead to a decrease in stomach acid secretion. Levothyroxine’s bioavailability can be adversely affected by low stomach acidity, making thyroid hormone replacement treatment less effective.

Several recent research studies report that vitamin C acidifies the stomach and lowers the gastric pH level, enhancing the solubility of levothyroxine and its absorption."

Has anyone else heard of this and tried it? I'm interested to see if it works as I assumed my vitamin C tablets should be taken at least four hours after my Levothyroxine.

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TooManyTablets
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Regenallotment profile image
RegenallotmentAmbassador

it’s mentioned in some of Izabella Wentz books, she has a website, thyroidpharmacist.com she recommends a squeeze of lemon in warm water.

Just look after your teeth though, if doing this regularly.

Low FT3 is commonly associated with reflux conditions (I had this, ENT specialist agreed that sorting thyroid hormone replacement optimally was my best treatment) .

I took betain HCl with high protein meals for some months and eventually after giving up dairy and gluten things have resolved . I still take it occasionally when I’ve over eaten or feel dairy-d or gluten-d it aids the digestion of whatever isn’t suiting me. But best taken while eating, not before or after.

Have you tried the bicarbonate of soda test for low stomach acid? I think there is a YouTube. I did, it confirmed my suspicions. If you don’t have it the betaine HCl will give you instant heartburn. Family tried it and only 2 of us needed it.

I also have Vit C powder which I use occasionally if constipated or have a cold or feel dehydrated.

TooManyTablets profile image
TooManyTablets in reply toRegenallotment

Thank you for your suggestions.I've just tried the bicarbonate of soda test, on a empty stomach, and I managed one burp after ten minutes.

It doesn't surprise me that I seem to have this, especially after reading some of the symptoms of low stomach acid.

Regenallotment profile image
RegenallotmentAmbassador in reply toTooManyTablets

Apparently (according to my ENT) worst thing we hypos can do is take a PPI, but so many are prescribed. Absolute minefield. Good luck on your quest, I wish you swift digestion 🤗

Poppy_Ann profile image
Poppy_Ann

Hi, i take both vit c plus levothyroxine plus several different pain killers (which do not kill pain they just reduce it a small amount) and they all go down the hatch together as I cannot remember to take them at different times I take all of them in a morning and all except vitamin c and levothyroxine plus three others that I do not take in the morning which brings a total of 10 each morning and 11 each evening I do not take my lunch time pain meds unless my pain gets to high.I have not had a problem with taking the two together and my readings are in the middle of the recommended levels.

Regards Poppy Ann

Hectorsmum2 profile image
Hectorsmum2

I remember reading on here a long time ago that vit c increases absorbtion of levo not sure where to find the stud now. I take vit c with my thyroid hormones and it seems fine.

helvella profile image
helvellaAdministrator

Your post asks about vitamin C.

But you do not mention anything else contained in the vitamin C product you use. For example, many people take an effervescent orange vitamin C. The list of ingredients can be significant and I would avoid the product because it is impossible to find out if there might be any interactions. (Actually, I'd avoid them altogether, but specifically when taking with levothyroxine.)

TooManyTablets profile image
TooManyTablets in reply tohelvella

Thank you for your advice. I was wondering after I posted my question, which vitamin C supplements are best to take. Unfortunately my current vitamin c does contain bulking agents e.t.c. so I'm thinking of maybe trying vitamin c powder. I also wondered if I could try diluted apple cider vinegar or maybe lemon tea instead?

Regenallotment profile image
RegenallotmentAmbassador in reply toTooManyTablets

Yep I have the powder form bought online. It’s used for cutting heroin by drug users so difficult to buy at a pharmacy.

Apple cider vinegar shots also work, I drizzle it on salads when it’s T shirt weather and I soups when it isn’t.

A squeeze of lemon in hot water is refreshing but again watch out for your teeth the acid does a number on your enamel.

helvella profile image
helvellaAdministrator in reply toTooManyTablets

Some people have tried a squirt of lemon juice.

The problem with all acids is that they can cause tooth damage. And ascorbates (salts of ascorbic acid) likely have no benefit at all in these circumstances.

BorzoiGalgo profile image
BorzoiGalgo in reply tohelvella

Indeed. I rotted my teeth by drinking water with a squeeze of lemon, had to get crowns on all across the top front. Never again!

diagnosed2013 profile image
diagnosed2013 in reply toTooManyTablets

Hi...I take these & just empty one out into my water bottle every morning...no nasties or fillers in these. Just ascorbic acid...I am very sensitive to fillers in meds & lots of allergies, but I can take these no problem 😊

I take these...
Francis_BE profile image
Francis_BE in reply toTooManyTablets

An interesting vitamin C is in the form of magnesium ascorbate. I buy it in 250 g jars, which makes it the cheapest vitamin C per gram. Ascorbate can be taken in large quantities without causing any problems. For example, 1 teaspoon every hour to get rid of severe constipation or an emerging viral infection. Magnesium is safe (but avoid calcium ascorbate powder, which is also available). Always prefer pure products, without excipients.

helvella profile image
helvellaAdministrator in reply toFrancis_BE

Magnesium ascorbate might be wonderful stuff and very safe - and cheap.

But it appears to me that it is the acidity of ascorbic acid which slightly enhances levothyroxine absorption. But Magnesium ascorbate is neutral (pH 7 or extremely close to that). Hence would seem to be unlikely to enhance absorption of levothyroxine.

tattybogle profile image
tattybogle

yes , ive seen studies that found vit c increases absorption of levo , can't remember the details off hand

..... but rather than trying to absorb more , why not just increase your dose slightly ?

TooManyTablets profile image
TooManyTablets in reply totattybogle

Thank you.I'm currently working on my doctor to increase my dose but you know what they're like!

Lunario profile image
Lunario

Just google for "pubmed thyroxine vitamin c".

I always take my thyroxine and liothyronine along with vitamin c enhanced water.

kiefer profile image
kiefer

Yes, you can improve absorption of levothyroxine by taking vitamin c, as long as it's in the form of ascorbic acid (acidic, ↓ pH) and not sodium ascorbate (buffered, basic ↑ pH). The dose of vitamin c tested was 500mg.

pubmed.ncbi.nlm.nih.gov/246...

Keep in mind that taking levothyroxine on a full glass (8 oz) of water will ↑ pH, so drink only as much water as is necessary to swallow the medication.

link.springer.com/article/1...

Star13 profile image
Star13

I read that too and had been struggling to push up my T4 so decided to start taking my Solgar 1000mg Vit C in the morning with my Levo. It did help push it up. I’ve just checked it is L-Ascorbic acid but it does have some other bits in it so perhaps I’m not doing the right thing🤷‍♀️

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