Oobie. I asked because a Testosterone supplement helped me heaps with absorbing NDT. Remember females have Testosterone too. Maybe get your estrogen, progesterone, testosterone levels checked. Don't accept "you are within range" from your GP, get your test results and check you are middle or upper range. I was 12 on the 8-35 testosterone rage and a GP wouldn't supplement, so I changed GPs.
Re receptors - I dont know. But I have tried mixing a few times and I never worked out how to get it right, I always felt sickly. I have NDT, Thyroxin (T4) and Tertroxin T3 in the fridge but feel the most normal on a variable dose of NDT.
I use my temp as a guide to dosage. I loose temp if I go off thyroid supplements. So for me I take a base dosage 90mg. 60 mg at 11pm and 30mg 4 am. Then at 10am I take my temp if it is going down below 36C I take 30mg more. That is all I will take for the day (120mg) unless I am sailing in the afternoon I will take another 30mg. If I took 120mg for a couple of days in a row I will begin to go Hyper. With NDT you start on 30mg daily and after a two weeks bump up to 60mg. Keep doing this until you go hyper, then take nothing for a few days until the hyper passes and then go back on the last good dose. Example - you are taking 150 in week 10 and you go hyper, have a break for a day, and start back on 120. Remember if you are busy physically or emotionally you will need more.
NDT and Thryroxin a very different drugs and need to be managed very differently. With Thyroxin you just saturate your body with storage hormone (T4) and hope you convert it. Nothing wrong with this except thyroxin has all these horrible side effects for some people. On NDT (I believe) our bodies become lazy about converting T4 and I basically run on the T3 in NDT. Hence having to take NDT multiple times per day, plus boosters depending on work load.
For me I feel better on NDT so I'm prepared to pay the exorbitant prices pharmacies are currently charging - which I dont understand - after all thousands of pigs are killed everyday for meat.
Re vits - I take a Mega Magnesium daily and have B12 shots monthly. They both help with brain fog. I also take D3, Iron/C, Iodine, mens multi vit once every few weeks. But don't notice anything.