Drs. Peatfield and Skinner - cell resistance.

Both Drs. seem to suggest that taking T3 or T4, when one is resistant to them, can lead to 'stacking' in the blood ie. accumulation, and that this can lead to symptoms of excess, eventhough the tissues aren't getting enough. Surely, if the tissues aren't aborbing and therefore not getting enough, there would be no symptoms of excess. I am very confused. These Drs. seem to contradict the recommended articles on resistance.

[marram]

T4 I can understand, but I thought if you were not using the T3 because of resistance, you would not get hyper symptoms. Like you, I'm confused! Do you have the actual articles, and could you put a link on? I'd like to read them

Marie XX

[Hidden in reply to marram]

The Drs. info. came from their books. The articles on resistance - see Blog "hyper but resistant" comments. Even inthe case of T4, why would it produce hyper symptoms if it is not absorbed. It would not be entering the tissues to cause this surely?

[shaws Administrator]

Can you give a reference re Dr P and Dr S comments, please.

This is from Dr Lowe on Thyroid Hormone Resistance

web.archive.org/web/2010122...

[Hidden in reply to shaws]

The comments come from "Your Thyroid and How TO Keep It Healthy" by Dr. Peatfield and Dr. Skinner's book whose title I can't remember. I can't reference the page, because they were borrowed. I noted the comment by Marram above. But surely if T4 was not being absorbed it would not produce hyper symptoms either? Also they did not seem to be suggesting merely high blood test results, but actual symptoms. Please help. In desperate confusion, Beech.

[Hidden]

I can see, if there is stacking in the blood, how that might lead to high levels of T3 and T4 (provided you are taking both) being recorded in blood tests which doctors might confuse for there being a problem with hyperthyroidism. Our GP once sent my daughter a panic letter telling her she had become "overactive" because her blood tests indicated as much. She was then on a low dose of thyroxine and could hardly move from the settee, let alone be active! There are all kinds of reasons why T4 is not converted to T3 (the active hormone) and why T3 is not absorbed by cells.thyroiduk.org.uk/tuk/about_...

Jane x x

[Hidden in reply to Hidden]

Thanks for reply. Please see above.

[Hidden in reply to Hidden]

The only way I can explain it to myself (I can't find any scientific reasons in Dr. Peatfield's book) is to put it the way my daughter explains it. She tells me that if she has anything with T4 in it (thyroxine, NDT) she very soon starts to feel "toxic", yet on T3 alone this does not happen. Dr Lowe advised her that she would soon know if she was taking too much T3 as she would have hyper symptoms, and at one time she was taking 200mcg per day. Jane x x

[sporty333 in reply to Hidden]

M doctor just suggested i have cell resistance and to keep upping my T3 until i get some reaction from it. Is this what your daughter did?

[Hidden in reply to sporty333]

Yes. She kept a diary and monitored her symptoms, pulse rate, temp. and BP. Her pulse rate has never gone above 60, or her temperature above 37, and sometimes her BP is still very low, but some of her symptoms have gone and she feels the T3 has raised her metabolism and kept her alive.

[Aurora-auspice]

Fascinating! Might explain a lot for me at the moment! Thank yo for bringing this to my attention!

Aurora x

[Hidden in reply to Aurora-auspice]

Please see above and any replies by Dr. Lowe to resolve the confusion.

[Hidden]

I haven't heard the term stacking before, the term usually used is "pooling" therefore if you want to research it, that term will produce a lot more information when you search

[Hidden in reply to Hidden]

Thanks.

[Heloise]

thyroid-rt3.com/whatdo.htm