Castration Resistant PC

[Squish2024]

We are 3 years into our journey and PC became castration resistant 6 months ago. 77 yo and started on triple therapy with Zytiga and have had one round of chemo. Cancer is Gleason 9, stage 4.

We started on Xofigo after the cancer became castration resistant but now the doc is recommending Pluvicto as Xofigo is not working. Chemo would be next if Pluvicto doesn’t work.

Amyone opted to skip Pluvicto and just do chemo again? Hoe effective is Pluvicto?

[speranza10]

Which chemo did you choose? Do you want to repeat the docetaxel or do cabazitaxel for the first time? From what I understand pluvicto is not the miracle treatment that we all hoped it would be, for some it works great for others it keeps the disease stable for a decent period of time and for others it doesn't work at all but unfortunately this is true for all treatments.

[Squish2024 in reply to speranza10]

Docetaxel. It was tolerated pretty well, other than some minor stomach issues and hair loss, the side the effects were minimal.

[speranza10 in reply to Squish2024]

If it worked and had no side effects, it is a good idea to repeat docetaxel, leaving jevtana and pluvicto for possible future use.

[gsun]

Get a PSMA PET scan to see how PSMA avid your cancer is. If a lot, then Pluvicto may be the way to go. Also, Pluvicto is more effective in the earlier stages,I believe.

[j-o-h-n]

Squish2024,

How about updating the bio?...... It helps us all..... thank you and keep posting!!!

BTW Squash is a very healthy vegetable to eat.

Good Luck, Good Health and Good Humor.

j-o-h-n