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CD19 CAR-T cell therapy for B-ALL achieved remarkable efficacy with a complete remission of 70–90%
This looks interesting but way over my knowledge base. Perhaps some of you super brains can figure this out. In recent years, the increasing advancements and applications of cellular immunotherapy have enabled the use of chimeric antigen receptor (CAR) T cell therapy, and it has emerged as an efficacious
This looks interesting but way over my knowledge base. Perhaps some of you super brains can figure this out. In recent years, the increasing advancements and applications of cellular immunotherapy have enabled the use of chimeric antigen receptor (CAR) T cell therapy, and it has emerged as an efficacious
Scout4answers
in
Advanced Prostate Cancer
2 years ago
Is this normal?
Hey everyone. My doctor has said after speaking with a gynaecologist that I have endo - I haven’t had a scan and finding it impossible to get one. I’ve been in agony for two weeks now, started during my period and still here afterwards - at first the pain was in the middle and now it’s moved to the right
Hey everyone. My doctor has said after speaking with a gynaecologist that I have endo - I haven’t had a scan and finding it impossible to get one. I’ve been in agony for two weeks now, started during my period and still here afterwards - at first the pain was in the middle and now it’s moved to the right
abbiecx_
in
Endometriosis UK
3 years ago
Next-level Dose Given in Trial of Stem Cell Therapy for Bradykinesia
IMAC Holdings has completed dosing the second group of patients in its Phase 1 clinical trial testing umbilical cord-derived mesenchymal stem cell therapy for the treatment of bradykinesia due to Parkinson’s disease. About a year ago, a first group of five patients received a low dose of the therapy
IMAC Holdings has completed dosing the second group of patients in its Phase 1 clinical trial testing umbilical cord-derived mesenchymal stem cell therapy for the treatment of bradykinesia due to Parkinson’s disease. About a year ago, a first group of five patients received a low dose of the therapy
Hidden
in
Cure Parkinson's
3 years ago
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Mouth ulcers
Hi all, I’m wondering if you can recommend anything to get rid of persistent mouth ulcers? I’m on humira (coming up to 6 months now - my rheumatologist insisted on keeping me on it even though it was doing nothing for me and she seems to have been right as it’s finally starting to work!), but I have
Hi all, I’m wondering if you can recommend anything to get rid of persistent mouth ulcers? I’m on humira (coming up to 6 months now - my rheumatologist insisted on keeping me on it even though it was doing nothing for me and she seems to have been right as it’s finally starting to work!), but I have
Emye343
in
NRAS
3 years ago
Researchers report third case of HIV remission after stem cell transplant using umbilical cord blood
A US woman has become the third known person who's gone into HIV remission, and the first mixed-race woman, thanks to a transplant of stem cells from umbilical cord blood, according to research presented at a conference Tuesday. https://edition.cnn.com/2022/02/15/health/hiv-third-person-remission/index.html
A US woman has become the third known person who's gone into HIV remission, and the first mixed-race woman, thanks to a transplant of stem cells from umbilical cord blood, according to research presented at a conference Tuesday. https://edition.cnn.com/2022/02/15/health/hiv-third-person-remission/index.html
Farooqji
in
Cure Parkinson's
3 years ago
Cord blood donation Northern Ireland
Does anyone know much about this? I’m very early on in pregnancy but heard about this years ago when beother in law had to have a stem cell transplant. I’m not sure if it’s available in Northern Ireland. Does it have to be donated or can it be froze for possible future use for child?
Does anyone know much about this? I’m very early on in pregnancy but heard about this years ago when beother in law had to have a stem cell transplant. I’m not sure if it’s available in Northern Ireland. Does it have to be donated or can it be froze for possible future use for child?
Babytwinkle
in
Pregnancy and Parenting Support
3 years ago
WARWICK's Latest Update on his POST ASCT journey thus far...
Post by MPN-MATE Admin » Sat Feb 12, 2022 10:39 pm Evening all... :D As some of you may recall, sometime ago in 2021, Warwick, (one of our committee members), underwent his Allogenic Stem Cell Transplant (ASCT) journey. While his condition is deemed a success, the journey itself remains ongoing w/
Post by MPN-MATE Admin » Sat Feb 12, 2022 10:39 pm Evening all... :D As some of you may recall, sometime ago in 2021, Warwick, (one of our committee members), underwent his Allogenic Stem Cell Transplant (ASCT) journey. While his condition is deemed a success, the journey itself remains ongoing w/
socrates_8
in
MPN Voice
3 years ago
10 Years With CLL: Two Trials & Lifesaving CAR T-Cell Therapy
I rarely cross post to Patient Power but today there is a story by a fellow CLL patient I have known for many years as DebinOz. She is one of the few I know of with a more aggressive form of CLL than mine. And I think she has more air miles than my 750,000 with United. Len - See: https://patientpower.info
I rarely cross post to Patient Power but today there is a story by a fellow CLL patient I have known for many years as DebinOz. She is one of the few I know of with a more aggressive form of CLL than mine. And I think she has more air miles than my 750,000 with United. Len - See: https://patientpower.info
lankisterguy
Volunteer
in
CLL Support
3 years ago
Happy to be here!
With everything that's been going on with my lung disease over the past few years, I often forget just how fortunate I am to still be here. In September 2003 I was diagnosed with chronic myeloid leukaemia at the age of 18. I was totally blindsided and the future looked bleak. The amazing treatments
With everything that's been going on with my lung disease over the past few years, I often forget just how fortunate I am to still be here. In September 2003 I was diagnosed with chronic myeloid leukaemia at the age of 18. I was totally blindsided and the future looked bleak. The amazing treatments
dodgylungrunner
British Lung Foundation
in
Lung Conditions Community Forum
3 years ago
Life expectancy with MF
Hello, all. I was diagnosed with post ET MF in 2019, after having been diagnosed with ET jak 2 in 2008. In 2019, I had my second BMB where it was confirmed I had progressed to MF, intermediate 1. I had a third BMB last September to determine whether I was a candidate for a bone marrow transplant. At
Hello, all. I was diagnosed with post ET MF in 2019, after having been diagnosed with ET jak 2 in 2008. In 2019, I had my second BMB where it was confirmed I had progressed to MF, intermediate 1. I had a third BMB last September to determine whether I was a candidate for a bone marrow transplant. At
Cja1956
in
MPN Voice
3 years ago
mouth ulcer remedy suggestions, pls
Currently recovering from a flare and I've got a mouth ulcer positioned within an awkward place on the roof of my mouth. Never had it there before! FYI - Alongside my Lupus, I also have Sjogren's. Any remedy suggestions would be greatly appreciated that doesn't involve reaching out to a GP. Thanking
Currently recovering from a flare and I've got a mouth ulcer positioned within an awkward place on the roof of my mouth. Never had it there before! FYI - Alongside my Lupus, I also have Sjogren's. Any remedy suggestions would be greatly appreciated that doesn't involve reaching out to a GP. Thanking
Amakura
in
LUPUS UK
3 years ago
Help make a drug to treat post-transplant CMV available to patients in Canada
If you have experienced Cytomegalovirus (CMV) following your Allogeneic Stem-Cell Transplant, you can help Canadian patients gain access to this treatment by completing our survey! You do not need to live in Canada to complete this survey. CLL Canada is working with a coalition of blood cancer patient
If you have experienced Cytomegalovirus (CMV) following your Allogeneic Stem-Cell Transplant, you can help Canadian patients gain access to this treatment by completing our survey! You do not need to live in Canada to complete this survey. CLL Canada is working with a coalition of blood cancer patient
CLL_Canada_Group
in
CLL Support
3 years ago
Jaw spasm & neck muscle problems?
Hi, I am new to this forum which I am now following on behalf of my husband. He has scleroderma primarily upper body, as a result of Chronic Graft vs Host Disease post stem cell transplant. He has had and still has many issues with c GvHD. This year he has developed 2 more problems which are proving
Hi, I am new to this forum which I am now following on behalf of my husband. He has scleroderma primarily upper body, as a result of Chronic Graft vs Host Disease post stem cell transplant. He has had and still has many issues with c GvHD. This year he has developed 2 more problems which are proving
AnnW22
in
Scleroderma & Raynaud's UK (SRUK)
3 years ago
Sudden Lymph Node Enlargement
I am a 58 year old female and was diagnosed a year ago. I have great bloodwork and have been without symptoms until a month ago & now have an enlarged lymph node that will require surgical removal for biopsy. The PET scan results are “worrisome for advanced lymphoma” and its hard not to mentally go
I am a 58 year old female and was diagnosed a year ago. I have great bloodwork and have been without symptoms until a month ago & now have an enlarged lymph node that will require surgical removal for biopsy. The PET scan results are “worrisome for advanced lymphoma” and its hard not to mentally go
StrengthHopeLove
in
CLL Support
3 years ago
Thoughts on hormonal coil?
Hello again everyone! Some TMI HERE - I'm physically and mentally exhausted currently with my pain and endometriosis symptoms. I had a coil put in 5 weeks ago after a failed lap to remove some of the endometriosis tissue (if mild - turns out my case was too severe to be treated and also there were other
Hello again everyone! Some TMI HERE - I'm physically and mentally exhausted currently with my pain and endometriosis symptoms. I had a coil put in 5 weeks ago after a failed lap to remove some of the endometriosis tissue (if mild - turns out my case was too severe to be treated and also there were other
Shels97
in
Endometriosis UK
3 years ago
Summary Paper from Drs, Claire N. Harrison and Donal P. McLornan
Nice summary I just came across from some of the experts. I've included some outtakes I found notable. Lots more in there on R&D for MF. https://onlinelibrary.wiley.com/doi/pdf/10.1111/bjh.16573 From chart, HCT control matters. This was discovered ~2011 and is likely a big part of what we've discussed
Nice summary I just came across from some of the experts. I've included some outtakes I found notable. Lots more in there on R&D for MF. https://onlinelibrary.wiley.com/doi/pdf/10.1111/bjh.16573 From chart, HCT control matters. This was discovered ~2011 and is likely a big part of what we've discussed
EPguy
in
MPN Voice
3 years ago
Cold sores
I was diagnosed in June 2019 with ET JAK 2 I am on Hydroxy and baby aspirin. Have any of you suffered with cold sores on mouth I am finding it very painful and I feel very down about it. I have called my surgery and have been prescribed Aciclovir 3 times a day for 5 days I am hoping they work as once
I was diagnosed in June 2019 with ET JAK 2 I am on Hydroxy and baby aspirin. Have any of you suffered with cold sores on mouth I am finding it very painful and I feel very down about it. I have called my surgery and have been prescribed Aciclovir 3 times a day for 5 days I am hoping they work as once
Tilly_Rose
in
MPN Voice
3 years ago
Problems with a sore and poisonous tasting mouth.
Any advise for my mother who is U.K. based would be much appreciated. For more than 15 years she has complained about a sore tongue and mouth and in her words that most food tasted like poison. I took her to see an oral Consultant who was a locum, he diagnosed sore mouth syndrome very quickly claiming
Any advise for my mother who is U.K. based would be much appreciated. For more than 15 years she has complained about a sore tongue and mouth and in her words that most food tasted like poison. I took her to see an oral Consultant who was a locum, he diagnosed sore mouth syndrome very quickly claiming
Hidden
in
Pernicious Anaemia Society
3 years ago
Mouth Ulcers Throat Irritation Adding to Furbie
I hope it is all right I started a new post.I also am struggling with mouth ulcers. I think they started when I had Covid in Nov. , and I have long covid still. Could be lupus related, hard to tell. The ones on the inside of my lips are annoying, but do do not hurt. The ones under the tongue area do
I hope it is all right I started a new post.I also am struggling with mouth ulcers. I think they started when I had Covid in Nov. , and I have long covid still. Could be lupus related, hard to tell. The ones on the inside of my lips are annoying, but do do not hurt. The ones under the tongue area do
Pumpkin2009
in
LUPUS UK
3 years ago
INF+ ATO Study, "A knockout combination for MPN stem cells"
Some have likely seen this study. I looked into it some more today and realize it's a neat pre-clinical result. This is just FYI right now but it's an example of potential good things to come. (I just noticed Manouche posted on this last year, anyway maybe some new details here) "JAK2V617F myeloproliferative
Some have likely seen this study. I looked into it some more today and realize it's a neat pre-clinical result. This is just FYI right now but it's an example of potential good things to come. (I just noticed Manouche posted on this last year, anyway maybe some new details here) "JAK2V617F myeloproliferative
EPguy
in
MPN Voice
3 years ago
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