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Vaccine efficacy for COPD and immune compromised people

macnsyl profile image
macnsyl
โ€ข18 Replies

Hi everyone.

Have any of you had any discussions with your medical team with respect to the efficacy of the Covid vaccines for people with compromised immune systems and COPD. I have COPD as well as having a stem cell transplant due to multiple myeloma. I have been in remission for 8 years but it is usual that people like me have a compromised immune system. I am not sure whether this results in lower antibody results after vaccination.

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macnsyl
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shouty profile image
shouty

I have Bronchiectasis and caught Covid in hospital while on high dose steroids for Nephrotic Syndrome . Had both doses of Pfizer in Feb & May and then an antibody tests few weeks later and it showed positive for antibodies which is a relief as still on Prednisolone. Of course it could have made those antibodies back in Dec when had Covid but I was very unwell with the kidney stuff at the time so who knows ?

macnsyl profile image
macnsylโ€ข in reply toshouty

This makes me feel better, thanks

shouty profile image
shoutyโ€ข in reply tomacnsyl

Pleased about that ๐Ÿ˜Š

shouty profile image
shoutyโ€ข in reply tomacnsyl

I was also lucky that I could attend special phlebotomy clinics for immunosuppressed & at risk folks as due to kidney problems needed fortnightly blood tests

Not had a specific discussion just be extra cautious any one who was advised to Shield.

You may want to look at video link from this page:

healthunlocked.com/blf/post...

I have multiple chronic illness risks for covid, I've had both vaccines of Pfizer.

I think the general theory / advice is, you are more protected having the vaccines than if you don't have the vaccines. Or other way round you are more at risk of severe illness from covid if you don't have the vaccine.

But yes for you personally you will need to check with your own consultant/s if you are concerned either way.

link from May 2021 - immuno suppressed were advised to have the vaccine at earliest as a priority in UK.

gov.uk/government/news/new-...

But whichever country you reside will have their own rules and recommendations.

Keep well and safe.

macnsyl profile image
macnsylโ€ข in reply to

Thank you. You seen always to have good advice.

โ€ข in reply tomacnsyl

Glad to be of help macnsyl :)

lung Canada have some info:

lung.ca/lung-health/lung-di...

you may want to check .gov.ca also for info

shouty profile image
shoutyโ€ข in reply to

Good article

AngieB72 profile image
AngieB72

I have to stay shielding as due to having rituximab infusions the vaccine has had no effect on my immune system - I have tested negative for antibodies created by vaccine twice. All my consultants can say is stay safe. Minimum contact with people and then only outside and at a distance. Definitely no public transport and avoid indoor spaces.

Hellodolly profile image
Hellodolly

Hi thereIt really depends on the type of immune issues you have. For most people with normal immunity, they will make antibodies, T cells and B cells via the vaccine and should therefore be protected, whatever the underlying condition.

If you are taking an immuno suppressant drug, your immune system will be compromised and youโ€™d need to check with your doctor about the vaccine.

If you are under an immunology team and have an immune deficiency or antibody deficiency , some people are making antibodies and some are not. PID Uk is the organisation for this group and there is an active Facebook group where people talk about this stuff.

I hope that helps.

macnsyl profile image
macnsylโ€ข in reply toHellodolly

Thank you. Not on these drugs presently.

Mooka profile image
Mooka

I am immune compromised from rituximab. I have been tested for antibodies and this has come back positive. However I understand these may have come from the immunoglobulin I inject every week as itโ€™s a human product. As Hellodolly said PID is a good place to check out. Sadly I do know of immunocompromised people who are testing negative. Thereโ€™s plenty of trials going on at the moment. One is looking at a nasal spray and another looking at trialing a third jab in the autumn.

macnsyl profile image
macnsylโ€ข in reply toMooka

Thank you

Izb1 profile image
Izb1

I have bronchiectasis and rheumatoid arthritis and on methorexate which stops your immune system working so will probably be at risk. Nobody has spoken to me about this. I would imagine its the same as when you have an infection, stop taking the methotexate until better, then restart. I dont think there is alot they can say, nobody knows how bad you will be if you get it, so just be careful and follow the rules, mask, handwash, distance . I have had both jabs, it would be silly not to x

macnsyl profile image
macnsylโ€ข in reply toIzb1

Thanks for the info.

Caspiana profile image
Caspiana

Hello macnsyl , ๐Ÿ˜Š๐Ÿ‘‹

I am also on a high volume of immunosuppressive drugs. I had a lung transplant almost two years ago. Unfortunately, a majority of us appear not retain antibodies. I am part of an online transplant forum based in the U.S. Many of the transplant patients ask for and receive antibody tests after their vaccinations. Very disappointingly the percentage that retain antibodies is low. The advise from the transplant hospitals right now is to continue with precautions, which I guess we would do anyway as we are vulnerable. P.S. This does not mean you definitely won't have antibodies. ๐Ÿ˜Š

Take care.

Cas ๐ŸŒฟ

macnsyl profile image
macnsyl

Thanks for the reply. No I am not on immure suppressive drugs. I had a stem cell transplant 7 years ago. Because the procedure kills your immune sytem with chemo the allows it to come back thanks to the stem cells, your system never achieves the same quality of immunity. I also have COPD, Multiple myeloma (in submission), diabetes. and overweight. Not a good recipe for Covid.

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