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Decision time. Input welcome
Saw my MO yesterday. I need to make a decision by next week on how to proceed. My personal life is imploding and all I see there is having to sell my house and move to... someplace -- long story, but everything I've tried has come up short. BTW, I live by myself with no close friends and only a very
Saw my MO yesterday. I need to make a decision by next week on how to proceed. My personal life is imploding and all I see there is having to sell my house and move to... someplace -- long story, but everything I've tried has come up short. BTW, I live by myself with no close friends and only a very
Miccoman
in
Advanced Prostate Cancer
2 years ago
Improvement of motor function in patients with AMN
[i]Cruising about for AMN clinical trials, I found this from the 2012 European Leukodystrophies Association:[/i] https://ela-asso.com/wp-content/uploads/2012/11/2012-ELA-Families-Scientists-Report.pdf Some stuff there about AMN, the usual suspects - stem cells and antioxidants, but this study about 4
[i]Cruising about for AMN clinical trials, I found this from the 2012 European Leukodystrophies Association:[/i] https://ela-asso.com/wp-content/uploads/2012/11/2012-ELA-Families-Scientists-Report.pdf Some stuff there about AMN, the usual suspects - stem cells and antioxidants, but this study about 4
monkeybus
in
AMN EASIER
2 years ago
Exercise Study of Function and Pathology for Women With X-linked Adrenoleukodystrophy
Has this been posted here before? Have it a second time if so. Read afresh if not.
Objective: To evaluate abnormalities of the brain and spinal cord by MRI in order to understand the mechanisms leading to the disability of women with adrenomyeloneuropathy and the effect of physical exercise.
Has this been posted here before? Have it a second time if so. Read afresh if not.
Objective: To evaluate abnormalities of the brain and spinal cord by MRI in order to understand the mechanisms leading to the disability of women with adrenomyeloneuropathy and the effect of physical exercise.
monkeybus
in
AMN EASIER
2 years ago
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Duke CHAMP trial results: Stable
Greetings brothers, Figured I'd give you an update from the Duke CHAMP clinical trial I was on. As a review, I had 8 courses of Docetaxel before I started the CHAMP trial. During the trial, we paused the immuno therapies twice due to Gastrointestinal havoc (extensive puking and diarrhea). The second
Greetings brothers, Figured I'd give you an update from the Duke CHAMP clinical trial I was on. As a review, I had 8 courses of Docetaxel before I started the CHAMP trial. During the trial, we paused the immuno therapies twice due to Gastrointestinal havoc (extensive puking and diarrhea). The second
HerbieP
in
Advanced Prostate Cancer
2 years ago
Curcumin New Promising MPN Study
Heads up , this post is dense, long, and detailed. -- There is a great thread going, initially about NAC supplement. It veered to Curcumin with Hunter's always knowledgeable influence. https://healthunlocked.com/mpnvoice/posts/147802945/nac-supp-continued?responses=147812549 Hunter referenced a study
Heads up , this post is dense, long, and detailed. -- There is a great thread going, initially about NAC supplement. It veered to Curcumin with Hunter's always knowledgeable influence. https://healthunlocked.com/mpnvoice/posts/147802945/nac-supp-continued?responses=147812549 Hunter referenced a study
EPguy
in
MPN Voice
2 years ago
Jacob Sands, MD, Thoracic Medical Oncologist, Explains Small Cell Lung Cancer, Treatments, Clinical Trials, and more...
Jacob Sands, MD, Thoracic Medical Oncologist, Dana-Farber Cancer Institute and Instructor of Medicine, Harvard Medical School explains the management of small cell lung cancer in a way that is easy to understand, encouraging, and full of valuable information! Watch the video here: https://www.youtube.com
Jacob Sands, MD, Thoracic Medical Oncologist, Dana-Farber Cancer Institute and Instructor of Medicine, Harvard Medical School explains the management of small cell lung cancer in a way that is easy to understand, encouraging, and full of valuable information! Watch the video here: https://www.youtube.com
AmyKamp
Partner
in
Small Cell Lung Cancer Support
2 years ago
Pregnancy concerns
Hello again, you helpful community. Don't worry if you don't have time to respond, but I thought I'd try. I've read the hypo in pregnancy information on various websites. Clinical trials and studies I've read scare me as I see there's little research in this and endocrinologist monitoring is most urgent
Hello again, you helpful community. Don't worry if you don't have time to respond, but I thought I'd try. I've read the hypo in pregnancy information on various websites. Clinical trials and studies I've read scare me as I see there's little research in this and endocrinologist monitoring is most urgent
hashihol
in
Thyroid UK
2 years ago
“The drug development landscape in Parkinson’s” by Dr Kevin McFarthing
I am delighted to announce our next zoom session that will be taking place at 7.30 pm London time on Monday, the 25th of April. We will have the pleasure of listening to Dr Kevin McFarthing who will update us on “The drug development landscape in Parkinson’s”. The presentation will give an overview
I am delighted to announce our next zoom session that will be taking place at 7.30 pm London time on Monday, the 25th of April. We will have the pleasure of listening to Dr Kevin McFarthing who will update us on “The drug development landscape in Parkinson’s”. The presentation will give an overview
Michel0220
in
Cure Parkinson's
2 years ago
Olaparib/Avastin for more than two years?
Hello everyone, I was all ready to wrap up my Avastin/olaparib treatment now that the two year mark is almost here. Everything I read everywhere says, Yep, two years of this maintenance after chemo and you're done. Now my onc today says "no need to cut it off if you don't want to, what do YOU want to
Hello everyone, I was all ready to wrap up my Avastin/olaparib treatment now that the two year mark is almost here. Everything I read everywhere says, Yep, two years of this maintenance after chemo and you're done. Now my onc today says "no need to cut it off if you don't want to, what do YOU want to
FlowerRose
in
My Ovacome
2 years ago
Encouraging results from the CureParkinsons supported Phase II clinical trial of the GLP-1R agonist Liraglutide
There were 37 randomly assigned to Liraglutide & 18 on placebo (2:1); At 54 weeks, non-motor symptoms scale scores had improved by 6.6 points in the liraglutide group & worsened by 6.5 points in the placebo group; MDS-UPDRS III (change from baseline) = not significantly different Secondary outcome analysis
There were 37 randomly assigned to Liraglutide & 18 on placebo (2:1); At 54 weeks, non-motor symptoms scale scores had improved by 6.6 points in the liraglutide group & worsened by 6.5 points in the placebo group; MDS-UPDRS III (change from baseline) = not significantly different Secondary outcome analysis
Hidden
in
Cure Parkinson's
2 years ago
Cause of metastasis in prostate cancer discovered
My post title is lifted directly from this article: https://www.sciencedaily.com/releases/2022/04/220404105723.htm Key quotes: “A research team at MedUni Vienna has now discovered specific changes in a protein that drive the growth and spread of prostate cancer. The study was recently published in the
My post title is lifted directly from this article: https://www.sciencedaily.com/releases/2022/04/220404105723.htm Key quotes: “A research team at MedUni Vienna has now discovered specific changes in a protein that drive the growth and spread of prostate cancer. The study was recently published in the
lokibear0803
in
Advanced Prostate Cancer
2 years ago
Light Therapy Clinical Trial
For those who might be interested, I received the message below from PhotoPharmics today providing an update to a light therapy clinical trial that I have been tracking for close to a year: Celeste Light for PD Trial Update As you may already know, organizing clinical trials can be difficult. We are
For those who might be interested, I received the message below from PhotoPharmics today providing an update to a light therapy clinical trial that I have been tracking for close to a year: Celeste Light for PD Trial Update As you may already know, organizing clinical trials can be difficult. We are
Canddy
in
Cure Parkinson's
2 years ago
Reply to queries on paper by Bianco et al
This is a reply to a group querying the validity of Bianco et al's paper on T4/T3 prefrence by some patients. I thought it nteresting to read the various arguments so I put it in full here, as it's behind a paywall. Response to Letter to the Editor From Bonnema et al: “Comparative Effectiveness of Levothyroxine
This is a reply to a group querying the validity of Bianco et al's paper on T4/T3 prefrence by some patients. I thought it nteresting to read the various arguments so I put it in full here, as it's behind a paywall. Response to Letter to the Editor From Bonnema et al: “Comparative Effectiveness of Levothyroxine
diogenes
in
Thyroid UK
2 years ago
Bronchiectasis clinical trials
Hi All, Not sure if the following might be of interest, perhaps some of you are already involved but you never know. https://clinicaltrials.gov/ct2/show/NCT04594369 If anyone has any feedback, would be pleased to hear. Have a good day, Chris.
Hi All, Not sure if the following might be of interest, perhaps some of you are already involved but you never know. https://clinicaltrials.gov/ct2/show/NCT04594369 If anyone has any feedback, would be pleased to hear. Have a good day, Chris.
LissacFrance
in
Lung Conditions Community Forum
2 years ago
Micro-Mets Next Steps
Beloved, well-read, much-experienced cancer colleagues, My PSA has gone up quite slowly since being OFF all ADT since 2015-16 clinical trial on Lupron and Apaludimide (I had heart attack and a TIA then- my oncologist has not urged me to go back on ADT since). My PSA is now just under 2.7 but was 1.4
Beloved, well-read, much-experienced cancer colleagues, My PSA has gone up quite slowly since being OFF all ADT since 2015-16 clinical trial on Lupron and Apaludimide (I had heart attack and a TIA then- my oncologist has not urged me to go back on ADT since). My PSA is now just under 2.7 but was 1.4
SeattleDan
in
Advanced Prostate Cancer
2 years ago
Latest from BATman Denmeade
New paper [1].
Bipolar androgen therapy (BAT): A patient's guide
[i]Bipolar androgen therapy (BAT) is a new treatment concept for men whose prostate cancer has become resistant to standard hormone-blocking therapy. Over the past decade, we have performed a series of clinical studies testing BAT
New paper [1].
Bipolar androgen therapy (BAT): A patient's guide
[i]Bipolar androgen therapy (BAT) is a new treatment concept for men whose prostate cancer has become resistant to standard hormone-blocking therapy. Over the past decade, we have performed a series of clinical studies testing BAT
pjoshea13
in
Advanced Prostate Cancer
2 years ago
Effect of Melatonin Administration on Mitochondrial Activity and Oxidative Stress Markers in Patients with Parkinson’s Disease 2021
The full report is available to read. Results are based on lab tests, but still very exciting. Interesting that they took 25 mg at noon and 25 mg 30 minutes before bedtime: Effect of Melatonin Administration on Mitochondrial Activity and Oxidative Stress Markers in Patients with Parkinson’s Disease https
The full report is available to read. Results are based on lab tests, but still very exciting. Interesting that they took 25 mg at noon and 25 mg 30 minutes before bedtime: Effect of Melatonin Administration on Mitochondrial Activity and Oxidative Stress Markers in Patients with Parkinson’s Disease https
Bolt_Upright
in
Cure Parkinson's
2 years ago
CD19 CAR-T cell therapy for B-ALL achieved remarkable efficacy with a complete remission of 70–90%
This looks interesting but way over my knowledge base. Perhaps some of you super brains can figure this out. In recent years, the increasing advancements and applications of cellular immunotherapy have enabled the use of chimeric antigen receptor (CAR) T cell therapy, and it has emerged as an efficacious
This looks interesting but way over my knowledge base. Perhaps some of you super brains can figure this out. In recent years, the increasing advancements and applications of cellular immunotherapy have enabled the use of chimeric antigen receptor (CAR) T cell therapy, and it has emerged as an efficacious
Scout4answers
in
Advanced Prostate Cancer
2 years ago
Evusheld shots - What now?
I just had the two Evusheld shots this week. I had CLL for several years and last November completed a 15 month clinical trial (041702) with Ibrutinib, Obinituzumab and Venetoclax. Happily, at the end I was declared uMRD. I have had 3 Pfizer shots and then a Moderna a month ago. None of these generated
I just had the two Evusheld shots this week. I had CLL for several years and last November completed a 15 month clinical trial (041702) with Ibrutinib, Obinituzumab and Venetoclax. Happily, at the end I was declared uMRD. I have had 3 Pfizer shots and then a Moderna a month ago. None of these generated
Iupiter
in
CLL Support
2 years ago
LU177 3rd dose
Hi! Well finaly my dad got in to the Lu177 clinical trials in Moscow. 1st round was 23 of Feb, then 2nd in 24 of March. Both time he got 9Gb of Lu 177. PSA before 1st injection was 112 and before 2nd 63. In this clinical trial they are using smal dosage 3,5 Gb but with short gap 2-4 weeks. But we decided
Hi! Well finaly my dad got in to the Lu177 clinical trials in Moscow. 1st round was 23 of Feb, then 2nd in 24 of March. Both time he got 9Gb of Lu 177. PSA before 1st injection was 112 and before 2nd 63. In this clinical trial they are using smal dosage 3,5 Gb but with short gap 2-4 weeks. But we decided
Zhyravlik
in
Advanced Prostate Cancer
2 years ago
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