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Doxycycline
Bottom Line: Low-dose Doxycycline may be a useful add-on to other therapies, for a number of reasons: i) inhibition of mitochondrial protein synthesis, with decreased ATP and a slowing of proliferation ... ii) ... &, with a particularly detrimental effect on PCa stem cell-like cells iii) inhibition
Bottom Line: Low-dose Doxycycline may be a useful add-on to other therapies, for a number of reasons: i) inhibition of mitochondrial protein synthesis, with decreased ATP and a slowing of proliferation ... ii) ... &, with a particularly detrimental effect on PCa stem cell-like cells iii) inhibition
pca2004
in
Fight Prostate Cancer
2 years ago
A New Clinical Trial for Pain and Fibrosis in Chronic Pancreatitis!
Hi everyone! I wanted to announce that there's a new clinical trial testing proglumide for pain and fibrosis in chronic pancreatitis patients that is currently recruiting participants in the Washington, D.C. area! We helped design this trial, but we need your help to find participants and get this drug
Hi everyone! I wanted to announce that there's a new clinical trial testing proglumide for pain and fibrosis in chronic pancreatitis patients that is currently recruiting participants in the Washington, D.C. area! We helped design this trial, but we need your help to find participants and get this drug
Skye_MC
Administrator
in
Chronic Pancreatitis Support
2 years ago
Update on progress with MF and the FEDORA clinical trial
So to recap, I was diagnosed with primary MF in October 2022 and asked to join a new clinical trial called FEDORA. After many tests including a BMB, ultrasound on my abdomen, chest X-ray etc. I started on the pre medication of 400mg/day (in one dose) of Fedratinib in capsule form. This was the first
So to recap, I was diagnosed with primary MF in October 2022 and asked to join a new clinical trial called FEDORA. After many tests including a BMB, ultrasound on my abdomen, chest X-ray etc. I started on the pre medication of 400mg/day (in one dose) of Fedratinib in capsule form. This was the first
Flyingsteamer
in
MPN Voice
2 years ago
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Niacin and Butyrate: Nutraceuticals Targeting Dysbiosis and Intestinal Permeability in Parkinson’s Disease
[u]
"Future studies should study the effects of long-term supplementation of promising nutrients, such as butyrate and niacin, on their abilities to halt or reverse disease progression in PD. "
[/u] Niacin and Butyrate: Nutraceuticals Targeting Dysbiosis and Intestinal Permeability in Parkinson
[u]
"Future studies should study the effects of long-term supplementation of promising nutrients, such as butyrate and niacin, on their abilities to halt or reverse disease progression in PD. "
[/u] Niacin and Butyrate: Nutraceuticals Targeting Dysbiosis and Intestinal Permeability in Parkinson
Bolt_Upright
in
Cure Parkinson's
2 years ago
With love and in loving memory.
Happy New Year to you my fellow travelers, patients and caregivers alike. I send hope that 2023 brings answers to your disease and it’s challenges. The names of those we lost to lung cancer this year are not all known but they will not be forgotten. Their words and their lives remain alive on this board
Happy New Year to you my fellow travelers, patients and caregivers alike. I send hope that 2023 brings answers to your disease and it’s challenges. The names of those we lost to lung cancer this year are not all known but they will not be forgotten. Their words and their lives remain alive on this board
Denzie
Volunteer
in
Lung Cancer Support
2 years ago
Pomi-T vs Pom Juice
I take 1 cup of Pom Juice most days based on the study attached. Doesn't taste great but I mix it with 1/2 c of Beet Juice. All organic. I have seen some talk about using the supplement Pomi-t. When I read the studies, too my non-scientific brain, it certainly looks like Pom Juice is the better of the
I take 1 cup of Pom Juice most days based on the study attached. Doesn't taste great but I mix it with 1/2 c of Beet Juice. All organic. I have seen some talk about using the supplement Pomi-t. When I read the studies, too my non-scientific brain, it certainly looks like Pom Juice is the better of the
Teufelshunde
in
Advanced Prostate Cancer
2 years ago
High risk treatment - go conventional or experimental?
Hello Folks, Lots of great posts and discussions on this site. I thought I'd come aboard and get some feedback. 58 yrs old great health except for Gleason 4+4 = 8, in 3/6 biopsy cores (one side of prostate). Not sure why they only took 6 cores. PSA 24.1 back in November. Did a bone scan and a question
Hello Folks, Lots of great posts and discussions on this site. I thought I'd come aboard and get some feedback. 58 yrs old great health except for Gleason 4+4 = 8, in 3/6 biopsy cores (one side of prostate). Not sure why they only took 6 cores. PSA 24.1 back in November. Did a bone scan and a question
LongTimeRunning
in
Prostate Cancer Network
2 years ago
AMG 509 and CC-94676 Clinical Trials
Has anyone participated in the AMG 509 (immunotherapy) clinical trial or the CC-94676 (oral hormonal therapy) clinical trial? What side effects have you experienced? Were positive results achieved? Does anyone know if you choose one over the other, are you precluded from participating in the remaining
Has anyone participated in the AMG 509 (immunotherapy) clinical trial or the CC-94676 (oral hormonal therapy) clinical trial? What side effects have you experienced? Were positive results achieved? Does anyone know if you choose one over the other, are you precluded from participating in the remaining
Coop68
in
Advanced Prostate Cancer
2 years ago
Is it worth taking magnesium supplements?
On Christmas Day our family gathered at our place and after dinner, as usual, the conversation turned to medical topics. My aunt told us that her neighbor told her that Magnesium may prime the immune system to fight cancer and infections. Dr. Hess and scientists in Switzerland have now discovered that
On Christmas Day our family gathered at our place and after dinner, as usual, the conversation turned to medical topics. My aunt told us that her neighbor told her that Magnesium may prime the immune system to fight cancer and infections. Dr. Hess and scientists in Switzerland have now discovered that
donits
in
Advanced Prostate Cancer
2 years ago
Why is it critical to achieve a deep molecular response ?
»Reaching a Deep Molecular Remission is now considered a goal of therapy by many clinicians. The importance of a DMR for patients aiming to achieve Treatment Free Remission is recognized by the inclusion of DMR as an endpoint measure in clinical trials. Additionally, TFR is increasingly acknowledged
»Reaching a Deep Molecular Remission is now considered a goal of therapy by many clinicians. The importance of a DMR for patients aiming to achieve Treatment Free Remission is recognized by the inclusion of DMR as an endpoint measure in clinical trials. Additionally, TFR is increasingly acknowledged
Manouche
in
MPN Voice
2 years ago
Pluvicto advisable for low volume disease? A recent PSA scan showed one tumor in my spine and one and a rib but also castrate resistant
I’ve been on Orgovyx for the last 15 months and three months ago my PSA started to rise and is now at .44. I’ve been hearing rumors about clinical trials for low volume disease but don’t know anything more about it. Can anyone recommend a clinic in Europe that might be experimenting on this level?
I’ve been on Orgovyx for the last 15 months and three months ago my PSA started to rise and is now at .44. I’ve been hearing rumors about clinical trials for low volume disease but don’t know anything more about it. Can anyone recommend a clinic in Europe that might be experimenting on this level?
SViking
in
Advanced Prostate Cancer
2 years ago
Any one know about new immune response clinical trials for metastatic prostate cancer?
inhave a friend that had stage 4 prostate cancer he was treated with surgery and chemo but it has returned and is aggressive and spread. His PSA also went up, Trying to find out about the new trials that are aimed at him
inhave a friend that had stage 4 prostate cancer he was treated with surgery and chemo but it has returned and is aggressive and spread. His PSA also went up, Trying to find out about the new trials that are aimed at him
Zigzagzig
in
Prostate Cancer And Gay Men
2 years ago
Splenomegaly in Polycythemia Vera: Its Clinical Significance and its Relation to Symptoms
Background: Splenomegaly (SPML) in PV has been considered a diagnostic hallmark, associated with symptoms, affected clinical trial design, and influenced governmental approval of ropeginterferon α-2b. Whether SPML affects myelofibrosis-free and overall survival (MFS and OS) is unknown. Because of uncertainty
Background: Splenomegaly (SPML) in PV has been considered a diagnostic hallmark, associated with symptoms, affected clinical trial design, and influenced governmental approval of ropeginterferon α-2b. Whether SPML affects myelofibrosis-free and overall survival (MFS and OS) is unknown. Because of uncertainty
Manouche
in
MPN Voice
2 years ago
Zytiga failure after 4 years what now
Hi Diagnosed in 2016 had SBRT . Life good 2 years and found 1 met in lung . Did Lupron/zytiga PSA drop to under .1 for 2 years. Requested a vacation . 15 months later PSA rises do PSMA . One met on vertibrae only . Did SBRT and doc said let’s do lung met at the same time even though it’s not showing
Hi Diagnosed in 2016 had SBRT . Life good 2 years and found 1 met in lung . Did Lupron/zytiga PSA drop to under .1 for 2 years. Requested a vacation . 15 months later PSA rises do PSMA . One met on vertibrae only . Did SBRT and doc said let’s do lung met at the same time even though it’s not showing
Db999
in
Advanced Prostate Cancer
2 years ago
Zhittya announces "Safe and Effective" treatment for PD
I know many of us (including myself) are skeptical about this company (they charge 50 thousand if you want to be a 'volunteer test subject'). I don't begrudge anyone an honest living. So let's just hope they come up with some good results to help us. --------------------------------- "FGF-1, Zhittya
I know many of us (including myself) are skeptical about this company (they charge 50 thousand if you want to be a 'volunteer test subject'). I don't begrudge anyone an honest living. So let's just hope they come up with some good results to help us. --------------------------------- "FGF-1, Zhittya
PDWarrior1900
in
Cure Parkinson's
2 years ago
2022 Emerging Leaders Prize Awarded to 3 Researchers in UK
Awardees received a total of £220K funded by the will of scientist with the disease by Patricia Valerio, PhD | December 8, 2022 The Medical Research Foundation has awarded its sixth Emerging Leaders Prize to three lupus researchers in the U.K. The scientists received a total of £220,000 (around
Awardees received a total of £220K funded by the will of scientist with the disease by Patricia Valerio, PhD | December 8, 2022 The Medical Research Foundation has awarded its sixth Emerging Leaders Prize to three lupus researchers in the U.K. The scientists received a total of £220,000 (around
lupus-support1
Administrator
in
LUpus Patients Understanding and Support
2 years ago
Scientists using cells to hopefully grow "mini livers"
Just a super interesting article on a clinical trial that is using cells from donated livers to see if ectopic mini livers can be grown in human lymph nodes that would provide additional liver function in people with ESLD. 2027 is not too far away! Regenerative medicine is advancing yall! Exciting and
Just a super interesting article on a clinical trial that is using cells from donated livers to see if ectopic mini livers can be grown in human lymph nodes that would provide additional liver function in people with ESLD. 2027 is not too far away! Regenerative medicine is advancing yall! Exciting and
muffins7
in
British Liver Trust
2 years ago
Resveratrol and ET
Hi everyone, I’m wondering whether anyone has tried the natural phenol, Resveratrol, to help their platelet reduction? I’m calr positive ET on Hydrea which I hate taking for its toxic effect . My haematologist just continues to increase the dose to try to suppress rising platelet count. However I have
Hi everyone, I’m wondering whether anyone has tried the natural phenol, Resveratrol, to help their platelet reduction? I’m calr positive ET on Hydrea which I hate taking for its toxic effect . My haematologist just continues to increase the dose to try to suppress rising platelet count. However I have
myllo
in
MPN Voice
2 years ago
ART Effect of Vitamin D3 Supplements on Development of Advanced Cancer
Effect of Vitamin D3 Supplements on Development of Advanced Cancer ...randomized clinical trial with
25 871 patients
, from November 1, 2011, to December 31, 2017.
...supplementation with vitamin D3 reduced the incidence of advanced (metastatic or fatal) cancer in the overall cohort,
Effect of Vitamin D3 Supplements on Development of Advanced Cancer ...randomized clinical trial with
25 871 patients
, from November 1, 2011, to December 31, 2017.
...supplementation with vitamin D3 reduced the incidence of advanced (metastatic or fatal) cancer in the overall cohort,
RMontana
in
Active Surveillance - Prostate Cancer
2 years ago
Potential New Treatment for “Brain Fog” in Long COVID Patients
Although brain fog in thyroid patients has often been dismissed by medics (whether not understood, not believed, or some other reason, I cannot say). However, it is coming through as a recognised symptom of Long Covid. Hopefully, even if the actual detailed causes are slightly or radically different
Although brain fog in thyroid patients has often been dismissed by medics (whether not understood, not believed, or some other reason, I cannot say). However, it is coming through as a recognised symptom of Long Covid. Hopefully, even if the actual detailed causes are slightly or radically different
helvella
Thyroid UK
in
Thyroid UK
2 years ago
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