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Need to Change Treatment
So I have progression after two years on Ibrance and Letrozole. I have an opportunity to participate in a clinical trial in my town in which I would be randomly assigned to Giredestrant, a promising oral SERD (monotherapy) or both Giredestrant with a new Pikc3a drug. My standard of care option would
So I have progression after two years on Ibrance and Letrozole. I have an opportunity to participate in a clinical trial in my town in which I would be randomly assigned to Giredestrant, a promising oral SERD (monotherapy) or both Giredestrant with a new Pikc3a drug. My standard of care option would
Trissh
in
SHARE Metastatic Breast Cancer
8 months ago
Intense jaw pain (pt.2)
Three months ago my husband developed intense right jaw pain. After multiple scans showing "something" (thankfully no PSMA activity) he had a surgical bone biopsy 11/29. Two days ago we received the pathology report but have not been able to speak with the Dr. to help us understand it. The good news
Three months ago my husband developed intense right jaw pain. After multiple scans showing "something" (thankfully no PSMA activity) he had a surgical bone biopsy 11/29. Two days ago we received the pathology report but have not been able to speak with the Dr. to help us understand it. The good news
Decktime
in
Advanced Prostate Cancer
8 months ago
ST-067 in combination with pembrolizumab clinical trial
https://www.moffitt.org/clinical-trials-and-studies/clinical-trial-21340/
https://www.moffitt.org/clinical-trials-and-studies/clinical-trial-21340/
Maxone73
in
Advanced Prostate Cancer
8 months ago
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Anyone can access this article?
"As Bertagnolli steps in, NIH and FDA reenvision clinical trials and evidence generation"..it could be the modernization of clinical trials I have been waiting for The only Monica Bertagnolli I knew was a tough girl, I want to see if this Monica is also such a tough cookie https://cancerletter.com
"As Bertagnolli steps in, NIH and FDA reenvision clinical trials and evidence generation"..it could be the modernization of clinical trials I have been waiting for The only Monica Bertagnolli I knew was a tough girl, I want to see if this Monica is also such a tough cookie https://cancerletter.com
Maxone73
in
Advanced Prostate Cancer
8 months ago
new clinical trial Risvodetinib (IkT-148009)
The 201 Clinical Trial For Patients With Untreated Parkinson’s Disease The 201 Clinical Trial is a trial that will explore whether a novel drug, Risvodetinib (IkT-148009), can slow or halt progression of Parkinson’s disease. The trial will also evaluate whether Risvodetinib (IkT-148009) can partially
The 201 Clinical Trial For Patients With Untreated Parkinson’s Disease The 201 Clinical Trial is a trial that will explore whether a novel drug, Risvodetinib (IkT-148009), can slow or halt progression of Parkinson’s disease. The trial will also evaluate whether Risvodetinib (IkT-148009) can partially
Boscoejean
in
Cure Parkinson's
8 months ago
first U.S. patients dosed in expanded Phase 1b clinical trial of CB307 for patients with mCRPC
one step at a time….immune therapy for prostate cancer is becoming hotter! https://finance.yahoo.com/news/crescendo-biologics-announces-first-u-120000112.html
one step at a time….immune therapy for prostate cancer is becoming hotter! https://finance.yahoo.com/news/crescendo-biologics-announces-first-u-120000112.html
Maxone73
in
Advanced Prostate Cancer
8 months ago
Vitamin D and Anemia: Insights into an Emerging Association
Found an interesting study. The conclusion sold it for me. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4659411/ CONCLUSION Vitamin D is associated with anemia in various study populations and recent evidence suggests that the association may differ by race and is likely specific to anemia of inflammation
Found an interesting study. The conclusion sold it for me. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4659411/ CONCLUSION Vitamin D is associated with anemia in various study populations and recent evidence suggests that the association may differ by race and is likely specific to anemia of inflammation
WideBody
in
Restless Legs Syndrome
8 months ago
New to this
I’m Jo, age 66, living in Chicago. I believe I have early stage PD. I haven’t been diagnosed yet have been acting out dreams for at least five years, and my right arm doesn’t swing. I’m hoping to get diagnosed soon so I can participate in a clinical trial.
I’m Jo, age 66, living in Chicago. I believe I have early stage PD. I haven’t been diagnosed yet have been acting out dreams for at least five years, and my right arm doesn’t swing. I’m hoping to get diagnosed soon so I can participate in a clinical trial.
Jomaxx
in
Cure Parkinson's
9 months ago
Provenge Complete
Well folks, I completed Provenge with no issues or SE’s to note. I understand my PSA will not be lowered by this treatment and it has gone way up, from 24 first of October to 58 last week. I am still waiting to hear from Sarah Cannon Research to review possible clinical trials. In a way I feel like
Well folks, I completed Provenge with no issues or SE’s to note. I understand my PSA will not be lowered by this treatment and it has gone way up, from 24 first of October to 58 last week. I am still waiting to hear from Sarah Cannon Research to review possible clinical trials. In a way I feel like
Pmann
in
Advanced Prostate Cancer
9 months ago
Doxorubicin pegylated liposomal
Hello Thrivers I hope you are all going well.I had a bone biopsy last week, I can honestly say it was a horrible experience. One I hope never to repeat. I have now been diagnosed with triple negative breast cancer. My first diagnoses was er+pr+ her 2 negative. Mets to bones and liver last September.
Hello Thrivers I hope you are all going well.I had a bone biopsy last week, I can honestly say it was a horrible experience. One I hope never to repeat. I have now been diagnosed with triple negative breast cancer. My first diagnoses was er+pr+ her 2 negative. Mets to bones and liver last September.
Cherry38
in
SHARE Metastatic Breast Cancer
9 months ago
BROQ/Prostaphane
Last week I had my 3 monthly PSA check and was happy and surprised to see that it had remained unchanged at 0.07. It had previously been creeping up and I am not currently on any treatement since my Cyberknife to a lymph node in December 21 together with 6 months of bicalutamide. I take a large variety
Last week I had my 3 monthly PSA check and was happy and surprised to see that it had remained unchanged at 0.07. It had previously been creeping up and I am not currently on any treatement since my Cyberknife to a lymph node in December 21 together with 6 months of bicalutamide. I take a large variety
GreenStreet
in
Fight Prostate Cancer
9 months ago
Richter's Transformation: standardized therapy or clinical trial
My father was diagnosed CLL 4 years ago and hasn't been treated. Recently he did a PET CT because of enlarged lmpth nodes and doctor said it's very possible he has Richter's Transformation. May I know if any one has same experience with Richters but not treated before? Could you share the treatment and
My father was diagnosed CLL 4 years ago and hasn't been treated. Recently he did a PET CT because of enlarged lmpth nodes and doctor said it's very possible he has Richter's Transformation. May I know if any one has same experience with Richters but not treated before? Could you share the treatment and
janeychen5712
in
CLL Support
9 months ago
Progressing nanotechnology to improve targeted cancer treatment: not related to prostate cancer only
The article emphasizes the challenges in transitioning from lab findings to clinical applications, stressing the need for further research to optimize nanocarriers for cancer therapy. It explores the potential of nanocarriers and compounds for selective tumor targeting, including liposomes, nanoparticles
The article emphasizes the challenges in transitioning from lab findings to clinical applications, stressing the need for further research to optimize nanocarriers for cancer therapy. It explores the potential of nanocarriers and compounds for selective tumor targeting, including liposomes, nanoparticles
Maxone73
in
Advanced Prostate Cancer
9 months ago
Psilocybin clinical trial
For people in both New York (NYU) and Colorado (CU Anschutz). Dont forget about the mental health side of fighting this dragon, whether traditional mental health services or something novel like this clinical trial. I’ve done traditional mental health (with anxiety meds) for a couple years now to help
For people in both New York (NYU) and Colorado (CU Anschutz). Dont forget about the mental health side of fighting this dragon, whether traditional mental health services or something novel like this clinical trial. I’ve done traditional mental health (with anxiety meds) for a couple years now to help
Chugach
in
Advanced Prostate Cancer
9 months ago
Hot off the press. Randomized, double-blind safety trial of high dose nicotinamide riboside in Parkinson’s disease.
Open access Published: 28 November 2023 Abstract Nicotinamide adenine dinucleotide (NAD) replenishment therapy using nicotinamide riboside (NR) shows promise for Parkinson’s disease (PD) and other neurodegenerative disorders. However, the optimal dose of NR remains unknown, and doses exceeding 2000
Open access Published: 28 November 2023 Abstract Nicotinamide adenine dinucleotide (NAD) replenishment therapy using nicotinamide riboside (NR) shows promise for Parkinson’s disease (PD) and other neurodegenerative disorders. However, the optimal dose of NR remains unknown, and doses exceeding 2000
SilentEchoes
in
Cure Parkinson's
9 months ago
Clinical trial for Metformin & Progressive MS
Hi All, I do podcasts interviewing doctors leading the newest breakthroughs in medicine. In my latest podcast, I interviewed Dr. Kevin Patel, MD, Neurologist at UCLA, who is leading a clinical trial related to MS. I thought this would be an important interview to share with you all that shares details
Hi All, I do podcasts interviewing doctors leading the newest breakthroughs in medicine. In my latest podcast, I interviewed Dr. Kevin Patel, MD, Neurologist at UCLA, who is leading a clinical trial related to MS. I thought this would be an important interview to share with you all that shares details
Shayan001
in
My MSAA Community
9 months ago
Quality of life questionnaire for hypothyroid?
Hi there, I've literally been diagnosed with hypothyroidism a week ago and started levothyroxine today, and feeling quite irritated really as it's clear to me now I've obviously had this a long time. TSH is 14.7 which doesn't seem great from what I am reading. What eventually got it diagnosed was me
Hi there, I've literally been diagnosed with hypothyroidism a week ago and started levothyroxine today, and feeling quite irritated really as it's clear to me now I've obviously had this a long time. TSH is 14.7 which doesn't seem great from what I am reading. What eventually got it diagnosed was me
Fweb
in
Thyroid UK
9 months ago
1st patient doesd in Phase 2 trial testing vaccine for Parkinson's
------------ The first patient has been dosed in a Phase 2 clinical trial testing AC Immune’s ACI-7104.056, an investigational vaccine targeting toxic alpha-synuclein forms to [u][i]
prevent nerve cell degeneration in Parkinson’s disease.
[/i][/u] AC Immune expects to complete the enrollment
------------ The first patient has been dosed in a Phase 2 clinical trial testing AC Immune’s ACI-7104.056, an investigational vaccine targeting toxic alpha-synuclein forms to [u][i]
prevent nerve cell degeneration in Parkinson’s disease.
[/i][/u] AC Immune expects to complete the enrollment
PDWarrior1900
in
Cure Parkinson's
9 months ago
FDA Investigating 'Serious Risk' of Malignancy After CAR-T Therapy - Applies to all approved therapies, but benefits still outweigh risks
From MedPage Today, by Charles Bankhead, Senior Editor, MedPage Today November 28, 2023, Last Updated November 29, 2023. Posted FYI without comment: [i]
FDA Investigating 'Serious Risk' of Malignancy After CAR-T Therapy - Applies to all approved therapies, but benefits still outweigh risks, agency
From MedPage Today, by Charles Bankhead, Senior Editor, MedPage Today November 28, 2023, Last Updated November 29, 2023. Posted FYI without comment: [i]
FDA Investigating 'Serious Risk' of Malignancy After CAR-T Therapy - Applies to all approved therapies, but benefits still outweigh risks, agency
cujoe
in
CLL Support
9 months ago
Genetic therapy: for solid malignancy hopefully soon
ok, I post them also because they are fellow Italians! But the platform is very promising even if clinical use has been approved only for glioma and glioblastoma at the moment. But there are clinical trials going on for solid tumors, prostate included. https://www.genenta.com/wp-content/uploads/2021
ok, I post them also because they are fellow Italians! But the platform is very promising even if clinical use has been approved only for glioma and glioblastoma at the moment. But there are clinical trials going on for solid tumors, prostate included. https://www.genenta.com/wp-content/uploads/2021
Maxone73
in
Advanced Prostate Cancer
9 months ago
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