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Transurethral resection of the prostate (TURP)
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Recent PSA test result no longer “undetectable.” What’s next?
After 5+ years of measuring “undetectable” with my PSA results I recently measured 0.24 NG/ML which I’m assuming my PCA is becoming active again. I see my oncologist on Monday, 8 Jan for a follow-up appt. Can anyone share with me what the likely next course of action will be?
After 5+ years of measuring “undetectable” with my PSA results I recently measured 0.24 NG/ML which I’m assuming my PCA is becoming active again. I see my oncologist on Monday, 8 Jan for a follow-up appt. Can anyone share with me what the likely next course of action will be?
Woodman33
in
Advanced Prostate Cancer
5 months ago
Happy New Year and Update
Update: I took what I hope will be my last Lupron shot which will work until March 5 /24. I will have had 31 months of Lupron with mostly undetectable PSA. I will have had 29 months of Abiraterone at that point. Had IMRT radiation 24 months ago Both my MO and RO are interested in whether they have
Update: I took what I hope will be my last Lupron shot which will work until March 5 /24. I will have had 31 months of Lupron with mostly undetectable PSA. I will have had 29 months of Abiraterone at that point. Had IMRT radiation 24 months ago Both my MO and RO are interested in whether they have
Scout4answers
in
Advanced Prostate Cancer
5 months ago
bicalutamide no longer as effective?
After more than two years of bicalutamide monotherapy and repeated PSA<0.1 I just received a 0.6. Before the bicalutamide my PSMA scan showed activity in only the seminal vesicle region. PSA was 2.5 at that time. Lupron had ceased being effective. Bicalutamide had a terrific response. I don’t think PSMA
After more than two years of bicalutamide monotherapy and repeated PSA<0.1 I just received a 0.6. Before the bicalutamide my PSMA scan showed activity in only the seminal vesicle region. PSA was 2.5 at that time. Lupron had ceased being effective. Bicalutamide had a terrific response. I don’t think PSMA
kreg001
in
Advanced Prostate Cancer
6 months ago
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Elevated PSA 8 weeks after Robotic Prostatectomy
At the age of 70 my most recent treatment was a Robotic Prostatectomy after which pathology report was Gl 3+4 prostate cancer, pT3a (EPE and bladder neck invasion), N1 (1/15 nodes positive), multiple positive margins.( Prior to that I underwent Cryotherapy for prostate cancer in Mar 2012.) My PSA level
At the age of 70 my most recent treatment was a Robotic Prostatectomy after which pathology report was Gl 3+4 prostate cancer, pT3a (EPE and bladder neck invasion), N1 (1/15 nodes positive), multiple positive margins.( Prior to that I underwent Cryotherapy for prostate cancer in Mar 2012.) My PSA level
OLDSALTY2008
in
Advanced Prostate Cancer
6 months ago
What’s after Lu-177 in Vancouver, BC?
Hi there, I’m located in Vancouver, BC 🇨🇦. My dad is on a clinical trial and after over a decade with this disease he has failed Zytiga, Xtandi, docetaxel, and is now on his 4/6 Lu-177 infusion. He’s castration-resistant and metastatic. PSA decreased considerably after the first Lu-177 infusion but
Hi there, I’m located in Vancouver, BC 🇨🇦. My dad is on a clinical trial and after over a decade with this disease he has failed Zytiga, Xtandi, docetaxel, and is now on his 4/6 Lu-177 infusion. He’s castration-resistant and metastatic. PSA decreased considerably after the first Lu-177 infusion but
PHnerd
in
Advanced Prostate Cancer
5 months ago
New hope for castrate resistant prostate cancer on the horizon
A new experimental drug is in development that reverses castrate resistance and makes the cancer amenable to further treatment. Early days yet but it looks interesting. https://www.theguardian.com/society/2023/oct/16/new-prostate-cancer-treatment-may-be-on-the-horizon-say-scientists
A new experimental drug is in development that reverses castrate resistance and makes the cancer amenable to further treatment. Early days yet but it looks interesting. https://www.theguardian.com/society/2023/oct/16/new-prostate-cancer-treatment-may-be-on-the-horizon-say-scientists
GeorgesCalvez
in
Advanced Prostate Cancer
8 months ago
The Science is Coming
Good to see the mini AZD5069 trial with enzalutamide offering another route to taming the beast. I am no scientist but as I understand it the target is myeloid white blood cells which can act to fuel tumours. The drup blocks the CXCR2 receptor and, in a small sample seems to have resulted in tumour shrinkage
Good to see the mini AZD5069 trial with enzalutamide offering another route to taming the beast. I am no scientist but as I understand it the target is myeloid white blood cells which can act to fuel tumours. The drup blocks the CXCR2 receptor and, in a small sample seems to have resulted in tumour shrinkage
GreenStreet
in
Prostate Cancer Network
8 months ago
Rising PSA 1 year after RALP
I've been getting ultra sensitive PSA tests every three months. These are the last three scores: 0.015 0.017 0.026 (First PSA test after surgery was <0.1) I am worried. Frightened, actually. Margins were not clear on my surgical biopsy, though gleason was only 3+3. Two biopsies prior
I've been getting ultra sensitive PSA tests every three months. These are the last three scores: 0.015 0.017 0.026 (First PSA test after surgery was <0.1) I am worried. Frightened, actually. Margins were not clear on my surgical biopsy, though gleason was only 3+3. Two biopsies prior
SmasherOfAjumma
in
Prostate Cancer Network
5 months ago
FDG+/PSMA- lesions
My dad has metastatic CRPC. Xtandi failed, but at the moment he is still on it as we evaluate possible treatment options. Today we received also results of PSMA PET CT - it it stated, that there are discrepancies (loss of PSMA expression) with at least 4 bone mets when compared to findings of FDG (
My dad has metastatic CRPC. Xtandi failed, but at the moment he is still on it as we evaluate possible treatment options. Today we received also results of PSMA PET CT - it it stated, that there are discrepancies (loss of PSMA expression) with at least 4 bone mets when compared to findings of FDG (
MyDad76
in
Advanced Prostate Cancer
8 months ago
Signatera tumor dna test
Has anyone heard of using the Signatera test from Natera to detect the presence of prostate cancer recurrence when PSA is rising but the PSMA PET scan is negative?
Has anyone heard of using the Signatera test from Natera to detect the presence of prostate cancer recurrence when PSA is rising but the PSMA PET scan is negative?
shihtzu124
in
Advanced Prostate Cancer
6 months ago
PSA Dropped after 22 days of Zytiga
On Nov 1, my cancer was diagnosed as castrate resistant. Abiraterone and Prednisone was added to Lupron. On November 3 I had a Lupron shot and started Abiraterone and Prednisone on November 10. Today I had a PSA test. My PSA dropped from 0.8 on November 1 to 0.44 today. I was not expecting such dramatic
On Nov 1, my cancer was diagnosed as castrate resistant. Abiraterone and Prednisone was added to Lupron. On November 3 I had a Lupron shot and started Abiraterone and Prednisone on November 10. Today I had a PSA test. My PSA dropped from 0.8 on November 1 to 0.44 today. I was not expecting such dramatic
dac500
in
Advanced Prostate Cancer
6 months ago
PSA Bounce
Hello and happy New year distinguished gentlemen. I was wondering if I may please get your input on my latest PSA which bounced from 1.2 to 1.6. Why did this happen and is this something I should be concerned about? Thanks so much. Regards.
Hello and happy New year distinguished gentlemen. I was wondering if I may please get your input on my latest PSA which bounced from 1.2 to 1.6. Why did this happen and is this something I should be concerned about? Thanks so much. Regards.
caysary
in
Advanced Prostate Cancer
5 months ago
PSA after radiation and Hormone therapy prognosis
https://meetings.asco.org/abstracts-presentations/218387 I have be searching for some data on the impact of radiation and short term hormone therapy on Intermediate cancer. If anyone else has some additional data or experiences please post Background. I finishing up 25 doses of radiation to the
https://meetings.asco.org/abstracts-presentations/218387 I have be searching for some data on the impact of radiation and short term hormone therapy on Intermediate cancer. If anyone else has some additional data or experiences please post Background. I finishing up 25 doses of radiation to the
Mgtd
in
Prostate Cancer Network
5 months ago
Dutasteride and PSA dropping
I started taking dustasteride about 1 month ago because of high DHT and my PSA dropped from 10 to 5.5. I've read that you are supposed to double the PSA to get an "equivalent" non-dutasteride level of 11. Does anyone understand why we are supposed to double the PSA value when taking dutasteride?
I started taking dustasteride about 1 month ago because of high DHT and my PSA dropped from 10 to 5.5. I've read that you are supposed to double the PSA to get an "equivalent" non-dutasteride level of 11. Does anyone understand why we are supposed to double the PSA value when taking dutasteride?
janebob99
in
Prostate Cancer Network
5 months ago
Retrograde ejaculation after turps
I doubt you will ejaculate any more more then you then you already have this because during surgery they destroy part of the mechanism that makes you ejaculate retro grade ejaculation is a myth it does not go backwards it was made up bye surgeons to cover up what they did doing any kind of exercise
I doubt you will ejaculate any more more then you then you already have this because during surgery they destroy part of the mechanism that makes you ejaculate retro grade ejaculation is a myth it does not go backwards it was made up bye surgeons to cover up what they did doing any kind of exercise
Lmee
in
Men's Health Forum (Penis Health)
2 years ago
Low Volume Low PSA Metastatic PC.
When my Oncologist refers to Low volume, Low PSA Oglimetastic PC, what is he saying about my disease? I’ve been oo Abiraterone followed by Xtandi with Lupron every 3 months and Zometa every 6.
When my Oncologist refers to Low volume, Low PSA Oglimetastic PC, what is he saying about my disease? I’ve been oo Abiraterone followed by Xtandi with Lupron every 3 months and Zometa every 6.
NDJIM
in
Advanced Prostate Cancer
6 months ago
Is retrograde ejaculation after TURP surgery reversible?
I've had retrograde ejaculation every since having had TURP surgery for BPH in Sep 2021. I recently started doing kegel exercises, having read that it may help reverse retrograde ejaculation. Has anyone tried this, and have you been successful? For the first time today since the TURP surgery, I noticed
I've had retrograde ejaculation every since having had TURP surgery for BPH in Sep 2021. I recently started doing kegel exercises, having read that it may help reverse retrograde ejaculation. Has anyone tried this, and have you been successful? For the first time today since the TURP surgery, I noticed
CCdn
in
Men's Health Forum (Penis Health)
2 years ago
Arx517 updates about the trial for metastatic castration resistant prostate cancer
”Following completion of the 21-day observation period at 3.4 mg/kg (Cohort 9), no dose limiting toxicities (DLTs) or serious adverse events (SAEs) were observed Two patients in Cohort 9 experienced rapid PSA reduction at three weeks post-treatment following the first ARX517 dose” https://www.biospace.com
”Following completion of the 21-day observation period at 3.4 mg/kg (Cohort 9), no dose limiting toxicities (DLTs) or serious adverse events (SAEs) were observed Two patients in Cohort 9 experienced rapid PSA reduction at three weeks post-treatment following the first ARX517 dose” https://www.biospace.com
Maxone73
in
Advanced Prostate Cancer
6 months ago
PSA rising
Hi to the most incredible and informative group. I have been on hormone injections every 3 months. Abiraterone 500 mg with food and 5mg pred. psa 0.8 has increased to 0.17 in 2 months. questions. Should I up Abiraterone to 1000mg to help lower psa or am I on the downward slope now? Diagnosed 2019
Hi to the most incredible and informative group. I have been on hormone injections every 3 months. Abiraterone 500 mg with food and 5mg pred. psa 0.8 has increased to 0.17 in 2 months. questions. Should I up Abiraterone to 1000mg to help lower psa or am I on the downward slope now? Diagnosed 2019
Lion321
in
Advanced Prostate Cancer
6 months ago
Lymparza not working
hi..my husband was initially diagnosed stage 4b in 2020. He did well on chemo, and lupron. He is also on xgeva. He then went on zytiga for about 7 months before it started failing. He did get accepted in the luteciun trial at Penn on control arm. He did very well on Xtandi but was ended this past Aug
hi..my husband was initially diagnosed stage 4b in 2020. He did well on chemo, and lupron. He is also on xgeva. He then went on zytiga for about 7 months before it started failing. He did get accepted in the luteciun trial at Penn on control arm. He did very well on Xtandi but was ended this past Aug
Happy1985
in
Advanced Prostate Cancer
5 months ago
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