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Two updates in the Guidelines for PBC
PRACTICE GUIDANCE Primary biliary cholangitis: 2021 practice guidance update from the American Association for the Study of Liver Diseases Lindor, Keith D.*,1; Bowlus, Christopher L.2; Boyer, James3; Levy, Cynthia4; Mayo, Marlyn5 Author Information Hepatology 75(4):p 1012-1013, April 2022. | DOI
PRACTICE GUIDANCE Primary biliary cholangitis: 2021 practice guidance update from the American Association for the Study of Liver Diseases Lindor, Keith D.*,1; Bowlus, Christopher L.2; Boyer, James3; Levy, Cynthia4; Mayo, Marlyn5 Author Information Hepatology 75(4):p 1012-1013, April 2022. | DOI
DonnaBoll
Administrator
in
PBC Foundation
3 months ago
One piece at a time.....
Over the next week or so, I'd like to familiarize you with the guidelines officially established regarding PBC. I will post of a section of the Guidelines. Any discussion or comments would be welcomed. The next guidelines we will talk about are the EASL Guidelines -the European Association for the
Over the next week or so, I'd like to familiarize you with the guidelines officially established regarding PBC. I will post of a section of the Guidelines. Any discussion or comments would be welcomed. The next guidelines we will talk about are the EASL Guidelines -the European Association for the
DonnaBoll
Administrator
in
PBC Foundation
3 months ago
Which tests do your providers recommend annually?
Hello Everyone, I was diagnosed in 2018 and have had no issues, as bloodwork abnormalities led to my diagnosis, rather than symptoms. Fortunately for me, after I began taking Ursodiol, I have had normal bloodwork also. However, I've bounced around providers, in part due to the pandemic, and in part
Hello Everyone, I was diagnosed in 2018 and have had no issues, as bloodwork abnormalities led to my diagnosis, rather than symptoms. Fortunately for me, after I began taking Ursodiol, I have had normal bloodwork also. However, I've bounced around providers, in part due to the pandemic, and in part
SciFiWriter
in
PBC Foundation
3 months ago
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Biliary CirrhosisPrimary Biliary Cirrhosis – Condition and Symptoms The liver secretes bile, a bodily fluid that is essential for the body to digest fats. It also helps the body to rid itself of toxic substances, cholesterol, and worn-out red blood cells. The ducts that release bile can become damaged
Biliary CirrhosisPrimary Biliary Cirrhosis – Condition and Symptoms The liver secretes bile, a bodily fluid that is essential for the body to digest fats. It also helps the body to rid itself of toxic substances, cholesterol, and worn-out red blood cells. The ducts that release bile can become damaged
DonnaBoll
Administrator
in
PBC Foundation
3 months ago
calcium supplements
I have locally advanced prostate cancer t3b no mo finished treatment rt/ht 2016,testosterone has never recovered and now I have severe osteoporosis, I have had 2 infusions of zoledronic acid, is it safe to take a calcium supplement which aren't supposed to be good for p/c .
I have locally advanced prostate cancer t3b no mo finished treatment rt/ht 2016,testosterone has never recovered and now I have severe osteoporosis, I have had 2 infusions of zoledronic acid, is it safe to take a calcium supplement which aren't supposed to be good for p/c .
Radars
in
Prostate Cancer Network
3 months ago
Prostrate Cancer treatment ADT
HiI am being treated for PC. After diagnose I was put on ADT treatment. This stops testosterone production. Had a bone scan and found I have osteopenia. I am taking a calcium citrate with vitamin D. Also once per week Alendronate 70mg. Has anyone else been in the same boat? Thanks
HiI am being treated for PC. After diagnose I was put on ADT treatment. This stops testosterone production. Had a bone scan and found I have osteopenia. I am taking a calcium citrate with vitamin D. Also once per week Alendronate 70mg. Has anyone else been in the same boat? Thanks
RWRB
in
Osteoporosis Support
3 months ago
Fibroids and Norethisterone, bleeding and spotting
Hi all, I know you've each got enough to deal with, but I've been having a difficult few months and am after some advice. In February I was diagnosed with multiple fibroids. One of them is very large. I've had several ultrasounds and a hysteroscopy booked in for this week. My periods were very heavy
Hi all, I know you've each got enough to deal with, but I've been having a difficult few months and am after some advice. In February I was diagnosed with multiple fibroids. One of them is very large. I've had several ultrasounds and a hysteroscopy booked in for this week. My periods were very heavy
Laura2306
in
Endometriosis UK
3 months ago
Haz58
Hello Haz58, I’m sorry you are having such a rotten time in sorting out the medications which you can tolerate. I could not take Azapriothine or Methotrexate but have settled reasonably happily with a daily routine of Bisoprolol, Levothyroxine, Amlodipine, Prednisolone, Ursodeoxycholic Acid, Losartan
Hello Haz58, I’m sorry you are having such a rotten time in sorting out the medications which you can tolerate. I could not take Azapriothine or Methotrexate but have settled reasonably happily with a daily routine of Bisoprolol, Levothyroxine, Amlodipine, Prednisolone, Ursodeoxycholic Acid, Losartan
Katiecatweazel
in
NRAS
3 months ago
Alendronic acid and raised Potassium levels
Hi I have been on Alendronic acid for 4 mths now. I have - 3 lumbar spinal osteoporosis but also have chronic kidney deficiency. My past two blood tests are showing raised 5.7 mmols/l and I’m wondering if it’s linked to my Alendronic acid?
Hi I have been on Alendronic acid for 4 mths now. I have - 3 lumbar spinal osteoporosis but also have chronic kidney deficiency. My past two blood tests are showing raised 5.7 mmols/l and I’m wondering if it’s linked to my Alendronic acid?
Ukalady
in
Bone Health and Osteoporosis UK
3 months ago
Stopping Alendronic Acid
I've been taking Alendronic Acid along with pred (on the insistence of GPs and rheumy) for 2 years. At last I've managed to get a Dexa scan and they told me that my bones are good/normal and that there is no need to take the AA. Do I need to taper or can I just stop?Also wouldn't it make sense to do
I've been taking Alendronic Acid along with pred (on the insistence of GPs and rheumy) for 2 years. At last I've managed to get a Dexa scan and they told me that my bones are good/normal and that there is no need to take the AA. Do I need to taper or can I just stop?Also wouldn't it make sense to do
Sammo47
in
PMRGCAuk
3 months ago
How To Make Melatonin Lotion : A More Efficient Way Of Getting Melatonin Compared To Oral Melatonin And A Surprise Finding
A major problem I see with oral melatonin is the very poor bioavailability of oral melatonin, thought to be around 3% in humans as discussed here : https://bmcpharmacoltoxicol.biomedcentral.com/articles/10.1186/s40360-016-0052-2#:~:text=Elimination%20half%2Dlives%20following%20oral,between%20the%20volunteers
A major problem I see with oral melatonin is the very poor bioavailability of oral melatonin, thought to be around 3% in humans as discussed here : https://bmcpharmacoltoxicol.biomedcentral.com/articles/10.1186/s40360-016-0052-2#:~:text=Elimination%20half%2Dlives%20following%20oral,between%20the%20volunteers
chartist
in
Cure Parkinson's
4 months ago
zoledronic acid infusion and calcium supplement
do people on here take a calcium supplement before and after the infusion,
do people on here take a calcium supplement before and after the infusion,
Radars
in
Bone Health and Osteoporosis UK
4 months ago
Alendronic acid and rls
I have osteoporosis, Dr's want me to go on either Alendronic acid , IV Zolendronic acid, or Subcutaneous Denosumab Does anyone know if they make RLS worse please
I have osteoporosis, Dr's want me to go on either Alendronic acid , IV Zolendronic acid, or Subcutaneous Denosumab Does anyone know if they make RLS worse please
antelope99
in
Restless Legs Syndrome
4 months ago
Alendronic Acid
Hi I've had PMR for over 4 years now and am on 3mg pred. as the last time I managed to reduce and come off pred. I had a flare up . I also take Alendronic Acid. I've had toothache in a lower back molar on and off for the past year and the dentist says I either need root canal work or have it extracted
Hi I've had PMR for over 4 years now and am on 3mg pred. as the last time I managed to reduce and come off pred. I had a flare up . I also take Alendronic Acid. I've had toothache in a lower back molar on and off for the past year and the dentist says I either need root canal work or have it extracted
Simplewish
in
PMRGCAuk
4 months ago
Gasoline?
A question for anyone who has found an answer... From 2018, when diagnosed, I have been told by doctors, urologists and oncologists that; "Testosterone, in prostate cancer, is like gasoline on a fire!" When I first heard this it seemed dubious since what I "knew" about PCa was that young men with
A question for anyone who has found an answer... From 2018, when diagnosed, I have been told by doctors, urologists and oncologists that; "Testosterone, in prostate cancer, is like gasoline on a fire!" When I first heard this it seemed dubious since what I "knew" about PCa was that young men with
VoxHope
in
Advanced Prostate Cancer
4 months ago
Alendronic Acid tablets
oncologist has started me on these tablets last 6 months for bone density 70mg once weekly 30 mins before food and to remain upright after taking them anyone else had problem with acid in stomach and very loose stool to a point of passing watered stool .had sample taken and no conclusion read on leaflet
oncologist has started me on these tablets last 6 months for bone density 70mg once weekly 30 mins before food and to remain upright after taking them anyone else had problem with acid in stomach and very loose stool to a point of passing watered stool .had sample taken and no conclusion read on leaflet
Chrisbaird
in
Advanced Prostate Cancer
4 months ago
Rheumatologist referral
Hi everyone I was diagnosed in October 2021 with PMR. I followed the doctors ‘normal’ reduction plan at first. I was able to get down to 5 mg with reasonable ease although I was never 100% free from some pain and stiffness but didn’t affect my qol . I then found this site and started to follow advice
Hi everyone I was diagnosed in October 2021 with PMR. I followed the doctors ‘normal’ reduction plan at first. I was able to get down to 5 mg with reasonable ease although I was never 100% free from some pain and stiffness but didn’t affect my qol . I then found this site and started to follow advice
MrsPractical
in
PMRGCAuk
4 months ago
Laparoscopy made everything 1000x times worse, anyone else?
Hi all, I wondered if anyone else had, had a bad experience with their laparoscopy? I have suffered with endometriosis for 18 years ((I am 34 yes old)) (constantly misdiagnosed, gas lighted, not listened to, told it was normal period pains and to "just get on with it" - you know the usual story for
Hi all, I wondered if anyone else had, had a bad experience with their laparoscopy? I have suffered with endometriosis for 18 years ((I am 34 yes old)) (constantly misdiagnosed, gas lighted, not listened to, told it was normal period pains and to "just get on with it" - you know the usual story for
Mia843
in
Endometriosis UK
4 months ago
PMR flare advice needed
I have messed up with dealing with a recent flare and would love your advice on where to go from here. I was stuck at 11mg Prednisolone for many months and then one day I felt a change. From then I have been able to taper at 0.5mg every 3 weeks. All was good until I got to 8.5mg. I did my usual - add
I have messed up with dealing with a recent flare and would love your advice on where to go from here. I was stuck at 11mg Prednisolone for many months and then one day I felt a change. From then I have been able to taper at 0.5mg every 3 weeks. All was good until I got to 8.5mg. I did my usual - add
Oh-my
in
PMRGCAuk
4 months ago
unsuccessful Laparoscopy
Hello, this is my first time posting so please bear with me! I have been struggling with symptoms of endometriosis since I could remember. I started my period at around 9 and I would say from 13+ my periods had been extremely painful, heavy, putting pressure on my bowels, mood swings etc (the list really
Hello, this is my first time posting so please bear with me! I have been struggling with symptoms of endometriosis since I could remember. I started my period at around 9 and I would say from 13+ my periods had been extremely painful, heavy, putting pressure on my bowels, mood swings etc (the list really
BitterSweet09
in
Endometriosis UK
4 months ago
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