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US names first 10 drugs for Medicare price negotiation
Other drugs on the list include Amgen's (AMGN.O) rheumatoid arthritis drug Enbrel, Boehringer Ingelheim and Eli Lilly's (LLY.N) diabetes drug Jardiance, J&J's arthritis and Crohn's disease medicine Stelara and insulin from Novo Nordisk (NOVOb.CO).
Sweet Syndrome Associated With Crohn’s Disease Developed After a Combo Therapy With Infliximab and Azathioprine
Patient responded well to interleukin inhibitor (anti IL-12, IL-23), ustekinumab (Stelara). It targets the two proteins IL-12 and IL-23, which are produced in the body to help fight infections by temporarily causing inflammation.
Most Inflammatory Disease Patients on Immunosuppressants Mount a Response to the COVID-19 Vaccine (But Can Vary a Lot by Medication)
IL-12/23 or IL-23 inhibitors include such therapies as Stelara, Tremfya, and Skyrizi; integrin inhibitors include Entyvio.
The other good news was that combining therapies, such as taking methotrexate along with a TNF inhibitor, did not have an additional reduction on antibody levels.
Should You Get the COVID-19 Vaccine During a Disease Flare-Up?
Azathioprine (Imuran)
Cyclophosphamide (Cytoxan) (oral)
TNF biologics (ex: Cimzia, Enbrel, Humira, Remicade, Simponi and Simponi Aria)
IL-6 biologics (ex: Actemra, Kevzara)
IL-1 biologics (ex: Kineret, Ilaris)
IL-17 biologics (ex: Cosentyx, Taltz)
IL-23 biologics (ex: Skyrizi, Tremfya)
IL-12/23 biologics (ex: Stelara
7 Questions to Ask Your Rheumatologist If You’re Nervous About Getting the COVID-19 Vaccine
Azathioprine (Imuran)
Cyclophosphamide (Cytoxan) (oral)
TNF biologics (ex: Cimzia, Enbrel, Humira, Remicade, Simponi and Simponi Aria)
IL-6 biologics (ex: Actemra, Kevzara)
IL-1 biologics (ex: Kineret, Ilaris)
IL-17 biologics (ex: Cosentyx, Taltz)
IL-23 biologics (ex: Skyrizi, Tremfya)
IL-12/23 biologics (ex: Stelara