Experiences with

Ranitidine

Ranitidine is not currently available in the UK or globally. It has been discontinued as a precaution because it may contain a small amount of an impurity that has been linked to an increased risk of cancer in animals. It's not yet known whether it will be available again in future.

Ranitidine is a medicine that reduces the amount of acid your stomach makes. It was used for indigestion, heartburn and acid reflux, gastro-oesophageal reflux disease (GORD – this is when you keep getting acid reflux), and to prevent and treat stomach ulcers.

Talk to your doctor if you have indigestion, or heartburn and acid reflux. There are similar medicines they can prescribe for you if you need treatment.

If you've taken ranitidine in the past, any risk is likely to be very low, but if you have any concerns, speak to a pharmacist or doctor.

Related links

Heartburn and acid reflux — Link to Related Condition

Indigestion — Link to Related Condition

Stomach ulcer — Link to Related Condition

Ranitidine: forum — Link to Useful Resource

Campaign Against Reflux Disease: charity — Link to Useful Resource

Guts UK: charity — Link to Useful Resource

HealthUnlocked contains information from NHS Digital, licensed under the current version of the Open Government Licence

385 public posts

Need of help

I have tried Esomeprazole, that didn’t work, Rabeprazole and Ranitidine it’s not working, now I’m on Pantoprazole with ranitidine and it very minimal help. Any suggestions?
Nifty7312 profile image

Be sure to bin any old Ranitidine (Zantac) because carcinogen levels rise as it's stored!

Be sure to bin any old Ranitidine (Zantac) because carcinogen levels rise as it's stored! The amount of NMDA goes up as the pills sit on a shelf. Bloomberg just put out a new article on it that goes into detail, with strong evidence.
TF--TolerizationFan profile image

Coming off PPIs

I've taken PPIs for 20 years, almost completely unmonitored, firstly and worryingly Ranitidine for 15 and Omeprazol for 5. I took them for reflux which has always been part of the IBS I've had since my 20s.I now want to stop taking Omeprazol as I feel it' s now a physical addiction and ineffective.
Orchard33 profile image
Orchard33
in IBS Network
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Low iron and PPIs

I am wondering if it might be from taking Lansoprazole as I was taking ranitidine until the middle of last year and it was withdrawn so was given the PPI instead. Has anyone else had any problems?
Cavlover profile image
Cavlover
in NRAS

I do not have AF and don’t know how to remove the AF community and add the community I need.

I don’t see any options and I think I was assigned to the AF community because I asked a question of one of the AF community members who had posted about Ranitidine use and substituting with Famotidine.
blueyes917438 profile image

Lansoprazole and diarrhoea

I've taken taken two Ranitidine but still feel acidy. Peptac works for a while but doesn't last.Does anyone have any suggestions please?
Smithie49 profile image

Country-wide medical records infer increased allergy risk of gastric acid inhibition

A newspaper article and a paper in Nature that raise questions about the effects of Proton Pump Inhibitors (PPI - such as Omeprazole, Lansoprazole, Dexlansoprazole, Esomeprazole, Pantoprazole and Rabeprazole), Sucralfate, H2-receptor antagonists (such as Cimetidine, Ranitidine, Famotidine, Nizatidine
helvella profile image
helvella
Thyroid UKin Thyroid UK

PPI's

I stopped them and went on to Ranitidine but that was taken off the market suddenly due to scares of some type.
ukjacisl profile image

switching from ranitidine to famotidine

Has anyone been on ranitidine for years and had to switch to famotidine because of the shortage of ranitidine? And if you did, did you have any problems?
mlp3434 profile image

Problems getting prescriptions for naproxen and omeprazole

The next time I asked for some omeprazole the surgery said no and offered me ranitidine instead, which I accepted as it was for a short course. I turned up at the pharmacist to pick it up and was handed some omeprazole after all....
JenniferW profile image
JenniferW
in NRAS

Ranitidine advice

Hi, does anyone know if Ranitidine triggers RLS?
Jumpey profile image

Presently taking Calquence for lymphoma. Also having pains in lower stomach area. Can I take ranitidine while taking Calquence?

Calquence and ranitidine
Agatesup profile image
Agatesup
in CLL Support

Ranitidine linked to Barrett’s Oesophegus?

Has anyone else developed the same condition as me, and also suspects that Ranitidine is a contributory factor?
Mark14 profile image

Any help re fatigue

Was taking 2400 mgs daily of Ranitidine daily up to being banned. Can’t take Omeprazole etc as allergic to PPis. Get a dreadful rash. Now on Famotidine max dose with a view to being increased. The fatigue means day to day living is immensely difficult.
tcromp888 profile image

Suspected GORD, acid reflux and nutrient malabsorption

My GP is useless and wont help me...gave me ranitidine and lansaprozole for a couple of weeks then nothing, now its impossible to get an appointment so ive given up!
moneyangel22 profile image

Redundant (tortuous colon)

Was initially prescribed Ranitidine, but it was soon removed from the market. Instead, I was given Famotidine and I must say this has had a profound effect as I rarely get stomach pain now, which is amazing. However, I still get acute nausea which is wearing particularly as I get this every day.
Baenav profile image
Baenav
in IBS Network

Digestive Issues

I’m on PPIs and ranitidine, I can’t eat meat or fish, nuts, biscuits and bread get stuck but right now eating anything is painful as if my gullet is sore. Can anyone suggest something that might help me please?
AMDP profile image

Ranitidine?

Fortunately my acid reflux seems to have reduced in the last couple of years but if it gets worse I would like to think that Ranitidine might become available again.
FernandoPo profile image

Covid Vaccine, medical conditions and allergies

Together with the medication I take if my FNDs starts worsing which is Naproxen, Amitriptyline, Atenolol, Sumatrptan and Ranitidine. Anyone concerned about the same things?
AngieB68 profile image

Difficulty getting prescribed H2 Blockers.

I was prescribed Ranitidine when I was discharged from hospital last January 2020. This was then withdrawn and since, my pharmacy has not been able to obtain the substitutes which the doctors have subsequently prescribed:- famotidine, cimetidine and nizatidine.
catlover50 profile image
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