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Bomedemstat trials
Hi everyone, I haven’t posted for a while as I’ve been trying to ignore this condition! Calr positive ET. I’m terrified of going back on Hydrea due to intolerable side effects and my very understanding MPN specialist nurse has been monitoring me. Sadly, my platelets are creeping up , lately to 845
Hi everyone, I haven’t posted for a while as I’ve been trying to ignore this condition! Calr positive ET. I’m terrified of going back on Hydrea due to intolerable side effects and my very understanding MPN specialist nurse has been monitoring me. Sadly, my platelets are creeping up , lately to 845
myllo
in
MPN Voice
11 months ago
PCNA gene attack -- for solid tumors
Pasted from a publicly avaiilable website A "holy grail" molecule that kills all solid cancer tumors, leaving other cells unaffected, has been developed by scientists. The team at the City of Hope, one of the largest cancer research and treatment organizations in the United States, made the breakthrough
Pasted from a publicly avaiilable website A "holy grail" molecule that kills all solid cancer tumors, leaving other cells unaffected, has been developed by scientists. The team at the City of Hope, one of the largest cancer research and treatment organizations in the United States, made the breakthrough
Derf4223
in
Advanced Prostate Cancer
11 months ago
New Pancreatitis Therapies: Current Clinical Trials! | Webinar Registration is now OPEN
August 15, 2023 | 10 AM PT | 1 PM EST
Join our informative webinar, “New Pancreatitis Therapies: Current Clinical Trials!” where we aim to educate and empower you, our pancreatitis community, about the latest research and therapies available for pancreatitis. This session will provide information
August 15, 2023 | 10 AM PT | 1 PM EST
Join our informative webinar, “New Pancreatitis Therapies: Current Clinical Trials!” where we aim to educate and empower you, our pancreatitis community, about the latest research and therapies available for pancreatitis. This session will provide information
Skye_MC
Administrator
in
Chronic Pancreatitis Support
11 months ago
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Trametinib MAPK inhibitor in ENZA-R pCA - very interesting
Many of us are ENZA resistant in the CRPC phase. In preclinical study in turns out that Trametinib + Enza has a profound effect on proliferation, especially with PTEN loss and PI3K mutations, the pCa is then very dependent on the MAPK signalling pathway. There is a clinical trial II open for new patients
Many of us are ENZA resistant in the CRPC phase. In preclinical study in turns out that Trametinib + Enza has a profound effect on proliferation, especially with PTEN loss and PI3K mutations, the pCa is then very dependent on the MAPK signalling pathway. There is a clinical trial II open for new patients
Hidden
in
Advanced Prostate Cancer
11 months ago
If your doctor worries that too much B12 is toxic, show them this study on ALS & B12
ALS is the same as Lou Gehrig's disease, and is also what Stephen Hawking had. It is a neurodegenerative disease, thought to mostly affect the motor neurons. Ryosuke Oki, et al, "Efficacy and Safety of Ultrahigh-Dose Methylcobalamin in Early-Stage Amyotrophic Lateral Sclerosis" JAMA Neurol. 2022;
ALS is the same as Lou Gehrig's disease, and is also what Stephen Hawking had. It is a neurodegenerative disease, thought to mostly affect the motor neurons. Ryosuke Oki, et al, "Efficacy and Safety of Ultrahigh-Dose Methylcobalamin in Early-Stage Amyotrophic Lateral Sclerosis" JAMA Neurol. 2022;
jade_s
in
Pernicious Anaemia Society
11 months ago
Intraductal Carcinoma & Cribiform pattern 4 treatment options?
Newly dx. PCa. with Intraductal carcinoma, IDC-P. This is the most aggressive prostate cancer type. In my case 4+3 with 70% pattern 4 with cribriform which make it even more worse. There are four types of pattern 4 (poorly formed glands, glomeruloid structures, cribriform glands, and fused glands) and
Newly dx. PCa. with Intraductal carcinoma, IDC-P. This is the most aggressive prostate cancer type. In my case 4+3 with 70% pattern 4 with cribriform which make it even more worse. There are four types of pattern 4 (poorly formed glands, glomeruloid structures, cribriform glands, and fused glands) and
FMOH_N
in
Advanced Prostate Cancer
11 months ago
Low-dose Aspirin.
I imagine that the new aspirin study [JAMA (1)] will get a lot of media play, but I will post anyway. A previous study concluded that the only people who benefit from low-dose aspirin are those who have already experienced a cardiovascular event. For everyone else, the risks obliterate any benefit
I imagine that the new aspirin study [JAMA (1)] will get a lot of media play, but I will post anyway. A previous study concluded that the only people who benefit from low-dose aspirin are those who have already experienced a cardiovascular event. For everyone else, the risks obliterate any benefit
pca2004
in
Fight Prostate Cancer
11 months ago
Potential immunotherapy for MBC
Hello ladies, it is my first post, I am writing from a small country in Europe, and I felt very grateful in the past months to discover your stories, since I've been diagnosed with de novo MBC (bone mets in spine and pelvis) this January, being aged 33. It gave me a lot of knowledge about my disease,
Hello ladies, it is my first post, I am writing from a small country in Europe, and I felt very grateful in the past months to discover your stories, since I've been diagnosed with de novo MBC (bone mets in spine and pelvis) this January, being aged 33. It gave me a lot of knowledge about my disease,
Any1989
in
SHARE Metastatic Breast Cancer
11 months ago
Augmenting Healthcare: The Transformative Power of Artificial Intelligence
In recent years, the marriage of artificial intelligence (AI) and healthcare has emerged as a game-changing alliance, revolutionizing the landscape of medical research, diagnosis, treatment, and patient care. The potential of AI to process vast amounts of data, extract meaningful insights, and assist
In recent years, the marriage of artificial intelligence (AI) and healthcare has emerged as a game-changing alliance, revolutionizing the landscape of medical research, diagnosis, treatment, and patient care. The potential of AI to process vast amounts of data, extract meaningful insights, and assist
SaskiaHU
HealthUnlocked
in
HealthUnlocked Blog
11 months ago
Lupkynis protects kidneys in lupus nephritis patients for up to 3 years
The therapy is an oral medication approved in US, UK, and EU Lupkynis (voclosporin) continues to be safe and to protect kidney function when taken for up to three years by patients with lupus nephritis, a kidney complication of lupus. That’s according to the full results from AURORA 2 (NCT03597464
The therapy is an oral medication approved in US, UK, and EU Lupkynis (voclosporin) continues to be safe and to protect kidney function when taken for up to three years by patients with lupus nephritis, a kidney complication of lupus. That’s according to the full results from AURORA 2 (NCT03597464
lupus-support1
Administrator
in
LUpus Patients Understanding and Support
11 months ago
Nymox Reports Successful New NYMOZARFEX (TM) Long-Term Prostate Cancer Treatment Clinical Trial Results
NYMOZARFEX 15 mg Minimal Treatment of Low Grade Prostate Cancer Leads to Significant Long-Term Reduction in Incidence of Associated Prostate Cancer Surgery and Radiotherapy IRVINE, CA (July 25, 2023) Nymox Pharmaceutical Corporation [OTC: NYMXF] (the “Company”) is pleased to announce today important
NYMOZARFEX 15 mg Minimal Treatment of Low Grade Prostate Cancer Leads to Significant Long-Term Reduction in Incidence of Associated Prostate Cancer Surgery and Radiotherapy IRVINE, CA (July 25, 2023) Nymox Pharmaceutical Corporation [OTC: NYMXF] (the “Company”) is pleased to announce today important
vforvendetta
in
Prostate Cancer Network
11 months ago
Mucuna Please Read..do the homework
i have noticed there is a lot of confusion regarding Mucuna supplements and dosages. There are 2 good published studies (see below for links) showing wide discrepancies regarding how much actual Levodopa content is in the supplement. Due to it being a food supplement there is little testing and regulation
i have noticed there is a lot of confusion regarding Mucuna supplements and dosages. There are 2 good published studies (see below for links) showing wide discrepancies regarding how much actual Levodopa content is in the supplement. Due to it being a food supplement there is little testing and regulation
BuSurfer
in
Cure Parkinson's
11 months ago
Immunotherapies for MBC?
When I search for “immunotherapy” on this site I mostly see posts related to other types of cancers, but not MBC. I believe there are a few immunotherapies approved for MBC and there are several in clinical trials, but unless I’m missing it they don’t seem to get much discussion on this board. Immunotherapies
When I search for “immunotherapy” on this site I mostly see posts related to other types of cancers, but not MBC. I believe there are a few immunotherapies approved for MBC and there are several in clinical trials, but unless I’m missing it they don’t seem to get much discussion on this board. Immunotherapies
Half-Full
in
SHARE Metastatic Breast Cancer
11 months ago
Trying To Hold Onto Hope
Hi all, I last wrote on here back in the fall because my dad was deteriorating quickly after ending 2nd round of chemo and his PSA went to the 300s (see my bio for his medical history). He was a candidate for Pluvicto, and was also put on Zytgea and a steroid before starting treatment which helped
Hi all, I last wrote on here back in the fall because my dad was deteriorating quickly after ending 2nd round of chemo and his PSA went to the 300s (see my bio for his medical history). He was a candidate for Pluvicto, and was also put on Zytgea and a steroid before starting treatment which helped
Sunnyday1122
in
Advanced Prostate Cancer
11 months ago
Waiting for PSA Rise Post-Surgery Before Obtaining PSMA-PET– waiting too long can put some patients at risk, MedPage Today, July 6, 2023.
[i]
Anthony D'Amico, MD, on Waiting for PSA Rise Post-Surgery Before Obtaining PSMA-PET – Study suggests that waiting too long before obtaining PSMA-PET can put some patients at risk, MedPage Today, ASCO > Prostate Cancer, by Jeff Minerd , Contributing Writer, July 6, 2023
[/i]. After radical
[i]
Anthony D'Amico, MD, on Waiting for PSA Rise Post-Surgery Before Obtaining PSMA-PET – Study suggests that waiting too long before obtaining PSMA-PET can put some patients at risk, MedPage Today, ASCO > Prostate Cancer, by Jeff Minerd , Contributing Writer, July 6, 2023
[/i]. After radical
cujoe
in
Fight Prostate Cancer
11 months ago
Dual ARi in mCRPCa - Antonarakis = 'Combo of 2 AR-directed agents should not be utilized in clinical practice at this time', MedPage 7/20/23
Posted without comment for the SOC crowd. [i]
Emmanuel Antonarakis, MD, on Dual Androgen Receptor Inhibition in Metastatic Castration-Resistant Prostate Cancer– 'Combination of two androgen-directed agents should not be utilized in clinical practice at this time', MedPage Today, ASCO > Prostate Cancer
Posted without comment for the SOC crowd. [i]
Emmanuel Antonarakis, MD, on Dual Androgen Receptor Inhibition in Metastatic Castration-Resistant Prostate Cancer– 'Combination of two androgen-directed agents should not be utilized in clinical practice at this time', MedPage Today, ASCO > Prostate Cancer
cujoe
in
Fight Prostate Cancer
11 months ago
Medium-Dose Lithium May Hit Parkinson Disease Targets...
I intentionally did not include the entire title of the article in the heading as I think it may be unnecessarily negative. Here is the article:
Medium-Dose Lithium May Hit Parkinson Disease Targets, but Tolerability Questioned
https://www.hmpgloballearningnetwork.com/site/altc/news/medium-dose-lithium-may-hit-parkinson-disease-targets-tolerability-questioned
I intentionally did not include the entire title of the article in the heading as I think it may be unnecessarily negative. Here is the article:
Medium-Dose Lithium May Hit Parkinson Disease Targets, but Tolerability Questioned
https://www.hmpgloballearningnetwork.com/site/altc/news/medium-dose-lithium-may-hit-parkinson-disease-targets-tolerability-questioned
Bolt_Upright
in
Cure Parkinson's
1 year ago
Reminder: The virtual LiveLung SCLC group meeting is on Monday, July 24th at 7 pm ET!
This month's expert speakers are National Institutes of Health/National Cancer Institute researchers, Dr. Anish Thomas and Dr. Melissa Abel. They will share information about the SCLC clinical trials being conducted at the NIH/NCI. Register here: https://us02web.zoom.us/meeting/register/tZwofuCorTosGdeKrSxPsiBNkmV3RKLBjDob
This month's expert speakers are National Institutes of Health/National Cancer Institute researchers, Dr. Anish Thomas and Dr. Melissa Abel. They will share information about the SCLC clinical trials being conducted at the NIH/NCI. Register here: https://us02web.zoom.us/meeting/register/tZwofuCorTosGdeKrSxPsiBNkmV3RKLBjDob
AmyKamp
Partner
in
Small Cell Lung Cancer Support
1 year ago
Clinical trials as a treatment option
When my mother was diagnosed with stage 3 cancer, I looked for clinical trials she could enter. I have worked in drug development for 12 years and yet it took me 6 hours to find the three most suitable clinical trials for her. In the next medical appointment, I presented those three trials to the oncologist
When my mother was diagnosed with stage 3 cancer, I looked for clinical trials she could enter. I have worked in drug development for 12 years and yet it took me 6 hours to find the three most suitable clinical trials for her. In the next medical appointment, I presented those three trials to the oncologist
N1ria
in
The Roy Castle Lung Cancer Foundation
1 year ago
Senescent neutrophils and their subsequent impact on tumor progression and therapy resistance
I will comment after studying this for awhile, but it does open up an additional treatment path(s?) for PCa. (Excerpts) Calcinotto's team discovered that prostate tumor cells produce a molecule, ApoE, which can bind to and influence a type of immune cells, neutrophils, resulting in these cells acquiring
I will comment after studying this for awhile, but it does open up an additional treatment path(s?) for PCa. (Excerpts) Calcinotto's team discovered that prostate tumor cells produce a molecule, ApoE, which can bind to and influence a type of immune cells, neutrophils, resulting in these cells acquiring
cigafred
in
Fight Prostate Cancer
1 year ago
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