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Triplet Therapy
When I first showed sign of castrate resistance I went in Daralutamide which worked for about 6 months. I then went into SPLASH trial which worked for about 8 months. I am now doing Provenge but I expect Docxatel in the near future. If I did triplet therapy ADT/DOCXATEL/ENZALUTAMIDE is it possible the
When I first showed sign of castrate resistance I went in Daralutamide which worked for about 6 months. I then went into SPLASH trial which worked for about 8 months. I am now doing Provenge but I expect Docxatel in the near future. If I did triplet therapy ADT/DOCXATEL/ENZALUTAMIDE is it possible the
Joeym1040
in
Advanced Prostate Cancer
7 months ago
Elevated PSA 8 weeks after Robotic Prostatectomy
At the age of 70 my most recent treatment was a Robotic Prostatectomy after which pathology report was Gl 3+4 prostate cancer, pT3a (EPE and bladder neck invasion), N1 (1/15 nodes positive), multiple positive margins.( Prior to that I underwent Cryotherapy for prostate cancer in Mar 2012.) My PSA level
At the age of 70 my most recent treatment was a Robotic Prostatectomy after which pathology report was Gl 3+4 prostate cancer, pT3a (EPE and bladder neck invasion), N1 (1/15 nodes positive), multiple positive margins.( Prior to that I underwent Cryotherapy for prostate cancer in Mar 2012.) My PSA level
OLDSALTY2008
in
Advanced Prostate Cancer
6 months ago
Which Treatment for These Biopsy Results?
I now have my biopsy results Gleason 3 + 4 ie 90% of 3 and 10% of 4 Grade 2 The consultant said it was Intermediate but at one point used the term Low intermediate. Is this latter term valid given the stats? T2a NO MO - but I am puzzled about this because although it was mostly all on the left side
I now have my biopsy results Gleason 3 + 4 ie 90% of 3 and 10% of 4 Grade 2 The consultant said it was Intermediate but at one point used the term Low intermediate. Is this latter term valid given the stats? T2a NO MO - but I am puzzled about this because although it was mostly all on the left side
Nordman
in
Advanced Prostate Cancer
4 months ago
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Persistent AF, Diltiazem, side effects or Menopause??
I apologise in advance for what will be quite a lengthy post.... :( I was diagnosed with persistent a year ago Oct 22, but likely I had it unknowingly for about 2 years prior and put breathlessness and tiredness to work/being unfit. I am 57. During that 12 months I was on Bisoprolol for 9 months and
I apologise in advance for what will be quite a lengthy post.... :( I was diagnosed with persistent a year ago Oct 22, but likely I had it unknowingly for about 2 years prior and put breathlessness and tiredness to work/being unfit. I am 57. During that 12 months I was on Bisoprolol for 9 months and
Tplongy
in
AF Association
7 months ago
Is feeling hot in face 24/7 a menopause symptom/ low estrogen symptom? Will it go away with HRT(estrogen patch)?
Does anyone feel hot in your face all the time? Not only am I having hot flashes but I am feeling hot in my face ALL f the time with no end. I went to my gynecologist and she said that it is because I have no estrogen due to lack of periods for 20 years of anorexia. She is suggesting the HRT estrogen
Does anyone feel hot in your face all the time? Not only am I having hot flashes but I am feeling hot in my face ALL f the time with no end. I went to my gynecologist and she said that it is because I have no estrogen due to lack of periods for 20 years of anorexia. She is suggesting the HRT estrogen
Hidden
in
Menopause and Perimenopause Support
7 months ago
Will HRT( estrogen patch) take away hot flashes and feeling hot all the time especially in my face?
I'm about to start the estrogen patch in a couple days after I see my gyno. I have no estrogen due to the fact that I haven't had a period in over 20 years due to chronic anorexia. So I'm having severe hot flashes and I feel hot all the time especially in my face. She feels the HRT and the will give
I'm about to start the estrogen patch in a couple days after I see my gyno. I have no estrogen due to the fact that I haven't had a period in over 20 years due to chronic anorexia. So I'm having severe hot flashes and I feel hot all the time especially in my face. She feels the HRT and the will give
Hidden
in
Menopause and Perimenopause Support
7 months ago
Radiotherapy for prostate local and retroperitoneal nodes
ADT of lupron and abiraterone has been pretty tolerable so far, almost four months - maybe I got cocky. Started my SBRT 28 fraction 70 Gy radiotherapy four days ago, mild to moderate urinary urgency and some burn started almost immediately. Diarrhea started at night after day four, mild so far. How
ADT of lupron and abiraterone has been pretty tolerable so far, almost four months - maybe I got cocky. Started my SBRT 28 fraction 70 Gy radiotherapy four days ago, mild to moderate urinary urgency and some burn started almost immediately. Diarrhea started at night after day four, mild so far. How
pj1121
in
Advanced Prostate Cancer
7 months ago
CAR-T Trial Update #3
Hello friends, I had planned on updating everyone much sooner, but life got in the way a bit. Last I wrote, I had received my T-cells back on June 5, 2023. The first few days were totally uneventful. I was walking the halls a lot, staying active, reading, and getting dressed in regular clothing every
Hello friends, I had planned on updating everyone much sooner, but life got in the way a bit. Last I wrote, I had received my T-cells back on June 5, 2023. The first few days were totally uneventful. I was walking the halls a lot, staying active, reading, and getting dressed in regular clothing every
nvp815
in
CLL Support
11 months ago
Estrodiol and PC
My husband has been rediagnosed with NMPC he is on ADT which is holding the Testosterone very low but psa shot upto 82. New MO is starting Enzalutimide plus continuing ADT. Not looking forward to the side effects, but will perservere until psa drops. We have been discussing using Estradiol to help
My husband has been rediagnosed with NMPC he is on ADT which is holding the Testosterone very low but psa shot upto 82. New MO is starting Enzalutimide plus continuing ADT. Not looking forward to the side effects, but will perservere until psa drops. We have been discussing using Estradiol to help
Knittingque
in
Advanced Prostate Cancer
7 months ago
Advise please
Where do I start 🙈i apologise now for the length of this but I am at my wits end. I will try & keep it brief. I have Bronchiectasis I believe through Covid diagnosed 2022. Under control Dystolic dysfunction - mild. Under Active Thyroid since 2006 under control. And now NAFLD. I currently take
Where do I start 🙈i apologise now for the length of this but I am at my wits end. I will try & keep it brief. I have Bronchiectasis I believe through Covid diagnosed 2022. Under control Dystolic dysfunction - mild. Under Active Thyroid since 2006 under control. And now NAFLD. I currently take
Pinkhealth61
in
British Liver Trust
7 months ago
Medical OR chemical castration
Hi All, Ok I am 79 and still in great physical condition. PR and ADT for 2 years. To date no unusual physical side effects other than zero sex drive. It looks as thought I will be on ADT until I die. PSA increasing monthly so I will try other chemicals. I want to remain in good shape until my number
Hi All, Ok I am 79 and still in great physical condition. PR and ADT for 2 years. To date no unusual physical side effects other than zero sex drive. It looks as thought I will be on ADT until I die. PSA increasing monthly so I will try other chemicals. I want to remain in good shape until my number
Stevegr
in
Advanced Prostate Cancer
7 months ago
Hot flashes from lack of estrogen
I have had anorexia for 27 yrs now. I'm 39 female. For the past 6 months or so I have been having severe hot flashes and I got my hormones checked at the gynecologist and she told me that I have low estrogen due to the malnutrition caused by the anorexia which is making my pituitary gland not produce
I have had anorexia for 27 yrs now. I'm 39 female. For the past 6 months or so I have been having severe hot flashes and I got my hormones checked at the gynecologist and she told me that I have low estrogen due to the malnutrition caused by the anorexia which is making my pituitary gland not produce
Hidden
in
Talk ED (eating disorders)
7 months ago
Dysautonomia in Sjögren's - Genital Sore/dry symptoms
Because of the shame or embarrassment sometimes involved in talking about vulvar or vaginal symptoms, I have not really gone into depth with my Rheumatologist. I am just wondering whether anyone has any tips of how to soothe:- Burning of the vagina or vulvaI Itchy vulva or vagina I am also going through
Because of the shame or embarrassment sometimes involved in talking about vulvar or vaginal symptoms, I have not really gone into depth with my Rheumatologist. I am just wondering whether anyone has any tips of how to soothe:- Burning of the vagina or vulvaI Itchy vulva or vagina I am also going through
Energy14
in
LUPUS UK
7 months ago
If these were your results what would you do?
So despite increasing my T3 dose my FT3 is staying at 5. My FT4 is falling. My symptoms are mostly in check these days but the fatigue and malaise is creeping higher again and it's starting to inhibit what I can do. (Noting that my estrogen is below range and I'm hoping to start HRT soon.) I'm sporadic
So despite increasing my T3 dose my FT3 is staying at 5. My FT4 is falling. My symptoms are mostly in check these days but the fatigue and malaise is creeping higher again and it's starting to inhibit what I can do. (Noting that my estrogen is below range and I'm hoping to start HRT soon.) I'm sporadic
WitchingHour2point0
in
Thyroid UK
7 months ago
Stopping Lupron
Today I’ve had my next medical check. PSA still undetectable after RT IMRT/VMAT to prostate bed and pelvic floor accompanied by 24 months of Lupron. This was my third regimen after DXed in 11/2017, for more details pls refer to my bio. I will now stop Lupron, let’s see what the future will bring.
Today I’ve had my next medical check. PSA still undetectable after RT IMRT/VMAT to prostate bed and pelvic floor accompanied by 24 months of Lupron. This was my third regimen after DXed in 11/2017, for more details pls refer to my bio. I will now stop Lupron, let’s see what the future will bring.
Nusch
in
Advanced Prostate Cancer
4 months ago
prostap hrt and hysterectomy
Hi I’m looking for some advice, I’ve always suffered with my periods since starting them. I’ve tried lots of different contraceptives and found I’m really sensitive. I’ve had 3 children and don’t plan to have any more. I had an ablation done in 2021 which reduced bleeding but made pain more intense
Hi I’m looking for some advice, I’ve always suffered with my periods since starting them. I’ve tried lots of different contraceptives and found I’m really sensitive. I’ve had 3 children and don’t plan to have any more. I had an ablation done in 2021 which reduced bleeding but made pain more intense
Jessdoss
in
Women's Health
7 months ago
Odd statement found in STAMPEDE trial results
"Hormone therapy can cause bone problems. But the trial found that abiraterone reduced the risk of serious bone problems by a half." https://www.cancerresearchuk.org/about-cancer/find-a-clinical-trial/a-trial-looking-at-hormone-therapy-with-other-treatments-for-prostate-cancer-stampede-trial-results
"Hormone therapy can cause bone problems. But the trial found that abiraterone reduced the risk of serious bone problems by a half." https://www.cancerresearchuk.org/about-cancer/find-a-clinical-trial/a-trial-looking-at-hormone-therapy-with-other-treatments-for-prostate-cancer-stampede-trial-results
Hidden
in
Advanced Prostate Cancer
7 months ago
what to do??
I am really struggling, I am wondering if I have hashimotos. Diagnosed with an underactive thyroid in march ( the day my dad died) just 6 months after losing my mother in law. Had gone to the drs thinking my HRT needed tweaking for my perimenopause symptoms. (Hair loss, brittle nails, weight gain, sweating
I am really struggling, I am wondering if I have hashimotos. Diagnosed with an underactive thyroid in march ( the day my dad died) just 6 months after losing my mother in law. Had gone to the drs thinking my HRT needed tweaking for my perimenopause symptoms. (Hair loss, brittle nails, weight gain, sweating
Vorney
in
Thyroid UK
7 months ago
From a Gleason 9 to a clean CT scan in 18 mos.
18 mos ago, my husband was told by his dr. that he "most likely had two or three good years left." (WHY do they say stupid things like that?) I think that a lot of people believe whatever the dr. says and subconsciously program themselves accordingly. I, on the other hand, thought to myself, "We'll
18 mos ago, my husband was told by his dr. that he "most likely had two or three good years left." (WHY do they say stupid things like that?) I think that a lot of people believe whatever the dr. says and subconsciously program themselves accordingly. I, on the other hand, thought to myself, "We'll
jtango
in
Advanced Prostate Cancer
7 months ago
How important is missing 2 months of ADT?
I'm one month into RT and ADT for 9 months. I chose monthly Eligard. The Urology office made a mistake and came in with a 3-month dose. When I told the nurse I had communicated my 1-month preference prior, she left the room. The Dr. came in, eyeballed the dosage, removed 2/3 and I received it. I was
I'm one month into RT and ADT for 9 months. I chose monthly Eligard. The Urology office made a mistake and came in with a 3-month dose. When I told the nurse I had communicated my 1-month preference prior, she left the room. The Dr. came in, eyeballed the dosage, removed 2/3 and I received it. I was
Eadgbe
in
Prostate Cancer Network
7 months ago
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