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ARASENS Darolutamide vs Placebo
This Kaplan-Meier plot show the Castration - Resistant Prostate Cancer Free survival probability (%) for two groups: (A)
Darolutamide
+ ADT + Docetaxel, versus (B)
Placebo
+ ADT + Docetaxel, taken at two different times: 2 years and 4 years. There is a very large increase in survival
This Kaplan-Meier plot show the Castration - Resistant Prostate Cancer Free survival probability (%) for two groups: (A)
Darolutamide
+ ADT + Docetaxel, versus (B)
Placebo
+ ADT + Docetaxel, taken at two different times: 2 years and 4 years. There is a very large increase in survival
janebob99
in
Advanced Prostate Cancer
6 months ago
ARASENS TRIAL: Darolutamide
This Kaplan-Mieir plot show the Castration - Resistant Prostate Cancer Free survival probability (%) vs time for two groups: (A) Darolutamide + ADT + Docetaxel, versus (B) Placebo + ADT + Docetaxel. There is a very large increase in survival probability with the Darolutamide group (A) vs Placebo group
This Kaplan-Mieir plot show the Castration - Resistant Prostate Cancer Free survival probability (%) vs time for two groups: (A) Darolutamide + ADT + Docetaxel, versus (B) Placebo + ADT + Docetaxel. There is a very large increase in survival probability with the Darolutamide group (A) vs Placebo group
janebob99
in
Advanced Prostate Cancer
6 months ago
ADT with radiation?
I have a G 4+3, considered to be unfavorable intermediate risk, but a Decipher score of .4, considered to be low risk. I have opted to have radiation to treat my PCa. Do I need to take ADT with the radiation therapy? My MO suggested 4 to 6 months of Orgavix (not sure if I'm spelling it correctly). If
I have a G 4+3, considered to be unfavorable intermediate risk, but a Decipher score of .4, considered to be low risk. I have opted to have radiation to treat my PCa. Do I need to take ADT with the radiation therapy? My MO suggested 4 to 6 months of Orgavix (not sure if I'm spelling it correctly). If
CBRD
in
Advanced Prostate Cancer
6 months ago
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still unsure about hysterectomy, been waiting over 1 year for op date, and taken a year to see consultant for a discussion
Was diagnosed with deep filtrating endometriosis and adenomyosis in 2019 following an MRI, and I am now awaiting a laporoscopy (been waiting over a year) and want to be under anaesthetic for that experience. Having a mirena coil was a positive thing for me, as stopped alot of the pain and heaviness of
Was diagnosed with deep filtrating endometriosis and adenomyosis in 2019 following an MRI, and I am now awaiting a laporoscopy (been waiting over a year) and want to be under anaesthetic for that experience. Having a mirena coil was a positive thing for me, as stopped alot of the pain and heaviness of
coletteholt
in
Endometriosis UK
6 months ago
Cyberknife+IMRT combination treatment for High Risk PCa, that has spread to the seminal vesicle.
Has anyone done a cyberknife-imrt combination radiation treatment for prostate cancer? My PCa has spread to the Seminal Vesicle. So, instead of a planned 5 session cyberknife treatment to the prostate only ( when the PCa was thought to be confined to the prostate), my doc is putting me on 3 cyberknife
Has anyone done a cyberknife-imrt combination radiation treatment for prostate cancer? My PCa has spread to the Seminal Vesicle. So, instead of a planned 5 session cyberknife treatment to the prostate only ( when the PCa was thought to be confined to the prostate), my doc is putting me on 3 cyberknife
Sushupthi
in
Advanced Prostate Cancer
2 months ago
Fed up at not being able to do basic stuff
Over last 2 years health wise gonw bad to worse. No energy little interest i. Going out or even getting dressed.I used to be very i dependent ie own diy. Cleani g shoppi g ect. Even had craft hobby.but now all i seemto want to do is sleep
Over last 2 years health wise gonw bad to worse. No energy little interest i. Going out or even getting dressed.I used to be very i dependent ie own diy. Cleani g shoppi g ect. Even had craft hobby.but now all i seemto want to do is sleep
lizaspo
in
British Liver Trust
8 months ago
life Insurance
I wanted to get opinions regarding my life insurance 800K which will be expiring in a couple of months. I have the option to roll it over to a universal policy but it’s going to cost me 2K a month. I’m still Homone sensitive. And been on ADT and Nubeqa (daroludimide) for the last couple of years. Had
I wanted to get opinions regarding my life insurance 800K which will be expiring in a couple of months. I have the option to roll it over to a universal policy but it’s going to cost me 2K a month. I’m still Homone sensitive. And been on ADT and Nubeqa (daroludimide) for the last couple of years. Had
JDKotter
in
Advanced Prostate Cancer
6 months ago
To those newly diagnosed! There is hope!
I was diagnosed with Parkinson’s in Dec 2018. My form of Parkinson’s has a huge psychological element that many of you can relate to. It’s obvious because of how quickly I progressed while I was getting diagnosed . My Dad who was my best friend and business partner died unexpectedly in 2013, which destroyed
I was diagnosed with Parkinson’s in Dec 2018. My form of Parkinson’s has a huge psychological element that many of you can relate to. It’s obvious because of how quickly I progressed while I was getting diagnosed . My Dad who was my best friend and business partner died unexpectedly in 2013, which destroyed
38yroldmale
in
Cure Parkinson's
10 months ago
ISO a third MO opinion for my dad
Hi all! My dad was diagnosed with pca in 2021, prostate removal that summer. After radical - was told no treatment necessary and lo and behold January the following year psa went from .04 to 1.2 in 3 months. Put on adt and zytiga (not sure of spelling), scans show pelvic bed spots and 1 on s1, radiation
Hi all! My dad was diagnosed with pca in 2021, prostate removal that summer. After radical - was told no treatment necessary and lo and behold January the following year psa went from .04 to 1.2 in 3 months. Put on adt and zytiga (not sure of spelling), scans show pelvic bed spots and 1 on s1, radiation
Dsmejkal88
in
Advanced Prostate Cancer
6 months ago
Dr Dipnarine Maharaj Immune Regenerative Medicine in Boynton Beach FL
Has anyone heard of him? I am about to start ADT and salvage radiation in 2 months (PSA 0.052) . So in mean time I was going to check him out and wondered if anyone who does a ton of research has heard of him?
Has anyone heard of him? I am about to start ADT and salvage radiation in 2 months (PSA 0.052) . So in mean time I was going to check him out and wondered if anyone who does a ton of research has heard of him?
Peppertree602
in
Advanced Prostate Cancer
6 months ago
PSA doubled in last 30 days after 4 months stable since Provenge. What's next?
Update: PSA remained roughly 1.7 to 1.8 for last 4 months after Provenge but yesterday's 30-day PSA test revealed a jump to 3.190 so something is growing quick. I have been off of all ADT since finishing fourth LU-177 injection five months ago and one SBRT treatment 4 months ago. After LU-177, PSA
Update: PSA remained roughly 1.7 to 1.8 for last 4 months after Provenge but yesterday's 30-day PSA test revealed a jump to 3.190 so something is growing quick. I have been off of all ADT since finishing fourth LU-177 injection five months ago and one SBRT treatment 4 months ago. After LU-177, PSA
SViking
in
Advanced Prostate Cancer
6 months ago
my first post
Hello there, I’ve been dealing with this since 1/2015. I’ve had brachytherapy, chemotherapy, hormone therapy, cyber knife, immunotherapy, more chemotherapy, now taking Everolimus and letrozole. I’ve always felt that this was a chronic disease after the medications stopped working onto the next regimen
Hello there, I’ve been dealing with this since 1/2015. I’ve had brachytherapy, chemotherapy, hormone therapy, cyber knife, immunotherapy, more chemotherapy, now taking Everolimus and letrozole. I’ve always felt that this was a chronic disease after the medications stopped working onto the next regimen
Sabrina02
in
SHARE Uterine Cancer Support
6 months ago
PSA vs Testosterone Nadir for CRPC and Non-CRPC
This plot from Safriadi (2022) compares the mean values of PSA nadir versus Testosterone Nadir comparing Non-Castrate Resistant PC (Non-CRPC) to Castrate-Resistant PC (CRPC) men. For Non-CRPC men, the range of T-nadir was 2.5-49 ng/dL (mean = 21) and range for PSA nadir was 0.02-9 ng/mL (mean=2). For
This plot from Safriadi (2022) compares the mean values of PSA nadir versus Testosterone Nadir comparing Non-Castrate Resistant PC (Non-CRPC) to Castrate-Resistant PC (CRPC) men. For Non-CRPC men, the range of T-nadir was 2.5-49 ng/dL (mean = 21) and range for PSA nadir was 0.02-9 ng/mL (mean=2). For
janebob99
in
Advanced Prostate Cancer
6 months ago
Can anyone help me please.....
Hi, can anyone help me with these test results please.I have Graves disease, Anemia, pernicious anemia, vitamin D deficiency and various other ailments, but I have been in remission from my graves for at least 5 years. I have been symptomatic a few times but it seems to correct itself, however my hubby
Hi, can anyone help me with these test results please.I have Graves disease, Anemia, pernicious anemia, vitamin D deficiency and various other ailments, but I have been in remission from my graves for at least 5 years. I have been symptomatic a few times but it seems to correct itself, however my hubby
Loza73
in
Thyroid UK
6 months ago
Help for a newbie at start of journey
Hi there. Just joined the forum and its a fantastic source of information - thank you. Was just diagnosed with hypothyroid a week ago after 4 years of feeling totally wiped out so trying to get to grips with it all and can see from the forum its a bit of a journey to try to get well again. Would appreciate
Hi there. Just joined the forum and its a fantastic source of information - thank you. Was just diagnosed with hypothyroid a week ago after 4 years of feeling totally wiped out so trying to get to grips with it all and can see from the forum its a bit of a journey to try to get well again. Would appreciate
Irish_Gal
in
Thyroid UK
6 months ago
CBD - my Mum's journey so far
Hello - I am so grateful to have found this group as I have felt alone given this disease is rare and even the health care professionals are not aware of it. I've detailed her journey which may help others trying to get a diagnosis. In 2019 my Mum's speech became slurred (only the family at this
Hello - I am so grateful to have found this group as I have felt alone given this disease is rare and even the health care professionals are not aware of it. I've detailed her journey which may help others trying to get a diagnosis. In 2019 my Mum's speech became slurred (only the family at this
Lalamccoy
in
PSP Association
10 months ago
Rising PSA post RP,IRT,ADT
Have 2 consecutive rising PSA - .04,.05,.1. Year post RP,IRT,ADT.. understand if goes to .2 new scans and possible Radiation. I surely don't like the ADT.. Any thoghts
Have 2 consecutive rising PSA - .04,.05,.1. Year post RP,IRT,ADT.. understand if goes to .2 new scans and possible Radiation. I surely don't like the ADT.. Any thoghts
ChristopherH
in
Advanced Prostate Cancer
6 months ago
Red Light Therapy
I have been using Wellreds Coronet for two years. I sleep extremely well since I started using it ( I had terrible sleep problems for years ). Worth every penny ! I use their preset program 2 x/day
I have been using Wellreds Coronet for two years. I sleep extremely well since I started using it ( I had terrible sleep problems for years ). Worth every penny ! I use their preset program 2 x/day
Defiance
in
Cure Parkinson's
10 months ago
Thyroid medication changes when starting HRT for perimenopause
I have been self medicating with liothyronine and levothyroxine for the past two years or so. Today I started the estrogen patch for perimenopause symptoms, and will also start progesterone in a couple of days. The provider that prescribed these said that some women need to increase their thyroid
I have been self medicating with liothyronine and levothyroxine for the past two years or so. Today I started the estrogen patch for perimenopause symptoms, and will also start progesterone in a couple of days. The provider that prescribed these said that some women need to increase their thyroid
TurtlesAllTheWay
in
Thyroid UK
6 months ago
At the crossroads (again)
My profile is up to date, but, briefly, have failed chemo, ADT (am castrate resistant), failed Keytruda and now Pluvicto. Scans yest. & today show progression along with PSA rise. All my mets are in bone. So, my SOC choices are cabazataxel or radium 223. Other options are trial, which are a crapshoot
My profile is up to date, but, briefly, have failed chemo, ADT (am castrate resistant), failed Keytruda and now Pluvicto. Scans yest. & today show progression along with PSA rise. All my mets are in bone. So, my SOC choices are cabazataxel or radium 223. Other options are trial, which are a crapshoot
rsgdmd
in
Advanced Prostate Cancer
6 months ago
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