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NHS agrees to roll out Olaparib (Lynparza) April 2023.
The NHS has agreed to Olaparib for advanced prostate cancer with mutations in the BRCA genes. ‘Hundreds of patients with advanced prostate cancer could benefit from a breakthrough targeted therapy after the NHS agreed a landmark commercial deal to roll-out the drug. The drug, olaparib (Lynparza®)
The NHS has agreed to Olaparib for advanced prostate cancer with mutations in the BRCA genes. ‘Hundreds of patients with advanced prostate cancer could benefit from a breakthrough targeted therapy after the NHS agreed a landmark commercial deal to roll-out the drug. The drug, olaparib (Lynparza®)
Sailing-Todd
in
Advanced Prostate Cancer
1 year ago
RLS - Q&A
Hi RLS survivors I am continuing my Pregabalin journey and wanted to check in with this community to ask out loud various questions circling around my head. The good news is that Pregabalin is making a difference. I get some relief from jumpy legs at night even on a low dose (75mg) What I am experiencing
Hi RLS survivors I am continuing my Pregabalin journey and wanted to check in with this community to ask out loud various questions circling around my head. The good news is that Pregabalin is making a difference. I get some relief from jumpy legs at night even on a low dose (75mg) What I am experiencing
careerSquirrel
in
Restless Legs Syndrome
10 months ago
Synthetic Hormones, Chemo & Radiotherapy
Hello, I am 60 years old, female,in the U.K., have had Primary Myelofibrosis for 20 years, treated with Aspirin & HU until recently, now switched to Anagrelide. I have recently been diagnosed with breast cancer, due to have lumpectomy next month, then there will be decisions to make about further treatments
Hello, I am 60 years old, female,in the U.K., have had Primary Myelofibrosis for 20 years, treated with Aspirin & HU until recently, now switched to Anagrelide. I have recently been diagnosed with breast cancer, due to have lumpectomy next month, then there will be decisions to make about further treatments
CraftySpider
in
MPN Voice
10 months ago
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SBRT alternative
So I've been trying to decide on what treatment I wanted to do and finally decided that I'd go with SBRT. Well unfortunately the MRIdian SBRT is going away at the end of the month. I reached out to Dr. Kishan to verify and this was the response "Unfortunately that is likely correct. We will be doing
So I've been trying to decide on what treatment I wanted to do and finally decided that I'd go with SBRT. Well unfortunately the MRIdian SBRT is going away at the end of the month. I reached out to Dr. Kishan to verify and this was the response "Unfortunately that is likely correct. We will be doing
MauiJef
in
Prostate Cancer Network
9 months ago
Orgovyx Insurance Approval
Anyone who is not on Medicare but relying on private insurance in getting approval for Orgovyx? I really want to avoid Lupron or Eligard since I take two blood pressure meds, one statin and Metformin for type 2 diabetes already. Plus, I have heard nothing but bad things about both. Yes, I realize
Anyone who is not on Medicare but relying on private insurance in getting approval for Orgovyx? I really want to avoid Lupron or Eligard since I take two blood pressure meds, one statin and Metformin for type 2 diabetes already. Plus, I have heard nothing but bad things about both. Yes, I realize
805guy
in
Prostate Cancer Network
10 months ago
Regret going to group therapy. Overwhelmed, another day wasted and money wasted. Why do all my attempts to get help backflip?
So i had a crisis some days ago and texted and old therapist that i loved. Told her it passed but now I'm wondering whether to go to group therapy. She said i deside but maybe it could be beneficial. At the last moment i went. Late. Saw people who just didn't feel right. Much older than me and with different
So i had a crisis some days ago and texted and old therapist that i loved. Told her it passed but now I'm wondering whether to go to group therapy. She said i deside but maybe it could be beneficial. At the last moment i went. Late. Saw people who just didn't feel right. Much older than me and with different
Against_the_current
in
Anxiety and Depression Support
1 year ago
HRT question.
Hi, I’m been on HRT for about 5 weeks now but my anxiety has just got worse. I’m having hot flashes today too, i feel my head is about to explode. Shouldn’t I be feeling a little bit better by now or is it too soon. Any thoughts please?
Hi, I’m been on HRT for about 5 weeks now but my anxiety has just got worse. I’m having hot flashes today too, i feel my head is about to explode. Shouldn’t I be feeling a little bit better by now or is it too soon. Any thoughts please?
BjAli
in
Menopause and Perimenopause Support
10 months ago
undiagnosed, unwell and with other autoimmune conditions .
hello, new here but user of HU due to other diagnosed AI condition in rheumatology field. Tests just starting to eliminate conditions, gastroscopy found nothing, abdominal scan pending, omeprazole prescribed. Existing condition Adult onset Stills Disease (1979) med free except pain relief, constant
hello, new here but user of HU due to other diagnosed AI condition in rheumatology field. Tests just starting to eliminate conditions, gastroscopy found nothing, abdominal scan pending, omeprazole prescribed. Existing condition Adult onset Stills Disease (1979) med free except pain relief, constant
Stills
in
Thyroid UK
10 months ago
Hot flushes and night sweats
Hi everyone I would like some advice please. I had been in HRT for 22 years (implants) but when I moved 8 years ago I couldn’t find a gynaecologist to do implants so I decided to stop using HRT. All was fine for 4/5years then I suddenly start having flushes during the day and night sweats which have
Hi everyone I would like some advice please. I had been in HRT for 22 years (implants) but when I moved 8 years ago I couldn’t find a gynaecologist to do implants so I decided to stop using HRT. All was fine for 4/5years then I suddenly start having flushes during the day and night sweats which have
Allot
in
Menopause and Perimenopause Support
10 months ago
[b]HOW LONG TO GET YOUR TESTOSTERONE BACK TO NORMAL (4-500) AFTER 4 MOS Treatment WITH ORGOVYX. It is now 5 months post treatment with Orgovyx.[/b]
[i]
HOW LONG TO GET YOUR TESTOSTERONE BACK AFTER 4 MOS TX WITH ORGOVYX.
[/i] Finally 7 mos . Post 20 imrt TX, 5 months post 4 mos. tx with Orgovyx, got my final blood labs:
PSA .2 PSA free.1
,very happy with this!
Testosterone 79
-VERY UNHAPPY WITH THIS ( still symptomatic for
[i]
HOW LONG TO GET YOUR TESTOSTERONE BACK AFTER 4 MOS TX WITH ORGOVYX.
[/i] Finally 7 mos . Post 20 imrt TX, 5 months post 4 mos. tx with Orgovyx, got my final blood labs:
PSA .2 PSA free.1
,very happy with this!
Testosterone 79
-VERY UNHAPPY WITH THIS ( still symptomatic for
JWS13
in
Advanced Prostate Cancer
9 months ago
biologic therapy blood tests to start Adalimumab
Hi after azaoprine caused liver cirrhosis, my consultant said I should start Adalimumab . I have had lots of various bloods taken including TB, HIV. Is this normal? 😳
Hi after azaoprine caused liver cirrhosis, my consultant said I should start Adalimumab . I have had lots of various bloods taken including TB, HIV. Is this normal? 😳
Bucket13
in
Crohn's and Colitis Support
1 year ago
grade and normal embryos link? help!?
Hi I am 27, no fertility issue (that i know of) non smoker, non drinking, took vitamins for 6 months prior to egg collection. Donor sperm used. I got 3 - 5day blastocysts from short protocol (8 eggs retrieved 6 fertilised) but all grade 3bb/3bc/3bc. 1st transfer failed - other 2 frozen. Someone
Hi I am 27, no fertility issue (that i know of) non smoker, non drinking, took vitamins for 6 months prior to egg collection. Donor sperm used. I got 3 - 5day blastocysts from short protocol (8 eggs retrieved 6 fertilised) but all grade 3bb/3bc/3bc. 1st transfer failed - other 2 frozen. Someone
Tryingforbabynow
in
Fertility Network UK
1 year ago
hormones
Any post-menopausal women out there? My symptoms of ADD -for me it’s really MDD motivation deficit disorder, have gotten much worse over the past couple of years. I am looking to go on Hormone Replacement Therapy- was wondering if anyone has experienced this and did it help?
Any post-menopausal women out there? My symptoms of ADD -for me it’s really MDD motivation deficit disorder, have gotten much worse over the past couple of years. I am looking to go on Hormone Replacement Therapy- was wondering if anyone has experienced this and did it help?
ADDSufferer
in
CHADD's Adult ADHD Support
10 months ago
Ten Months After All Treatments Ended
My Oncologist stopped my Eligard injections in October of 2022. My August 2023 bloodwork shows that my testosterone has risen from 2.0 to 10.0 in that time. My PSA was <0.1 ten months ago and is now 0.1 (Canadian units). I know that this cancer is a long game, but given my diagnosis in 2020, I am happy
My Oncologist stopped my Eligard injections in October of 2022. My August 2023 bloodwork shows that my testosterone has risen from 2.0 to 10.0 in that time. My PSA was <0.1 ten months ago and is now 0.1 (Canadian units). I know that this cancer is a long game, but given my diagnosis in 2020, I am happy
TottenhamMan
in
Advanced Prostate Cancer
10 months ago
RLS and HRT
I’ve always suffered mild rls in the evenings but some leg lifts and going to sleep stopped it , last few months it’s severe , I was up every half hour all last night walking the floors with restless legs , arms and stomach , my mind going haywire 🥴I think it could be linked to HRT and menopause but
I’ve always suffered mild rls in the evenings but some leg lifts and going to sleep stopped it , last few months it’s severe , I was up every half hour all last night walking the floors with restless legs , arms and stomach , my mind going haywire 🥴I think it could be linked to HRT and menopause but
Ronniebongo
in
Restless Legs Syndrome
10 months ago
HDR BT Salvage Therapy
Hello All I just completed the second BT procedure at MSK. Pain level was maybe 3 but mostly gone the next morning with some soreness. My next step I’m told is bloodwork in 3 months which I’m not concerned about. I am concerned about the 6 month MRI which could show if any cancer still remains. When
Hello All I just completed the second BT procedure at MSK. Pain level was maybe 3 but mostly gone the next morning with some soreness. My next step I’m told is bloodwork in 3 months which I’m not concerned about. I am concerned about the 6 month MRI which could show if any cancer still remains. When
Trying-Times
in
Advanced Prostate Cancer
1 year ago
Extreme sweats will they diminish; Zitiga is it worth it
I am 74 years of age and was initially diagnosed with prostate cancer Gleason 5+4 2011. I did not want and have had no surgery, no radiation and no treatment until starting ADT July, 2023. March of this year, I was hospitalized for what turned out to be kidney failure do to urine backing up into
I am 74 years of age and was initially diagnosed with prostate cancer Gleason 5+4 2011. I did not want and have had no surgery, no radiation and no treatment until starting ADT July, 2023. March of this year, I was hospitalized for what turned out to be kidney failure do to urine backing up into
Falcon10
in
Advanced Prostate Cancer
10 months ago
Coincidentally ...
.. a new study on CVD risk factors in men with PCa [1]: "
The Burden of Uncontrolled Cardiovascular Risk Factors in Men With Prostate Cancer: A RADICAL-PC Analysis
" The study found that most men with PCa have modifiable CVD risk factors. Although the authors recognize that CVD risk is
.. a new study on CVD risk factors in men with PCa [1]: "
The Burden of Uncontrolled Cardiovascular Risk Factors in Men With Prostate Cancer: A RADICAL-PC Analysis
" The study found that most men with PCa have modifiable CVD risk factors. Although the authors recognize that CVD risk is
pca2004
in
Fight Prostate Cancer
10 months ago
... what, then, do we die of?
New study of SEER data below [1]. The old comforting words that men with PCa "die with the disease, not of it" does not apply once mets occur, of course, but is largely true for local disease (the majority of cases in the U.S., due to screening practices.) It has long been known that men with PCa
New study of SEER data below [1]. The old comforting words that men with PCa "die with the disease, not of it" does not apply once mets occur, of course, but is largely true for local disease (the majority of cases in the U.S., due to screening practices.) It has long been known that men with PCa
pca2004
in
Fight Prostate Cancer
10 months ago
how fit can one be on ADT and abiraterone?
I have been on Lupron and abiraterone for less than two months and I have gone from doing 50 consecutive push ips to 10. I am slim on KETO diet but am disenchanted with the lack of ability to maintain any muscle. How much strength can be maintained on these meds?
I have been on Lupron and abiraterone for less than two months and I have gone from doing 50 consecutive push ips to 10. I am slim on KETO diet but am disenchanted with the lack of ability to maintain any muscle. How much strength can be maintained on these meds?
Nowhereman9
in
Advanced Prostate Cancer
10 months ago
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