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Natural desiccated thyroid (NDT)
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Natural T4 vs synthetic T4
Just wondering if she might be able to tolerate Armour or other
NDT
, eg. because the natural thyroxine is bound to a transport protein whereas the synthetic form is a sodium salt? Or maybe it's just that she's not a very good converter of T4 (whether natural or synthetic) to T3. Thoughts anyone.
Just wondering if she might be able to tolerate Armour or other
NDT
, eg. because the natural thyroxine is bound to a transport protein whereas the synthetic form is a sodium salt? Or maybe it's just that she's not a very good converter of T4 (whether natural or synthetic) to T3. Thoughts anyone.
tcpace
in
Thyroid UK
1 year ago
Time to PSA Nadir is related to progression-free-survival
This graph from Teoh (2014) plots the relationship between Time to PSA Nadir (months) versus Time to Progression (months) (i.e., Progression Free Survival). Cohort: ADT monotherapy (No RP or RT), all metastatic patients, median 74 y.o., GS = 8-10, N=419. A cubic spline curve fit matched the data points
This graph from Teoh (2014) plots the relationship between Time to PSA Nadir (months) versus Time to Progression (months) (i.e., Progression Free Survival). Cohort: ADT monotherapy (No RP or RT), all metastatic patients, median 74 y.o., GS = 8-10, N=419. A cubic spline curve fit matched the data points
janebob99
in
Advanced Prostate Cancer
6 months ago
lab draw
I am on
NDT
- same dose last 5mos. & just recently added a smidge more. I am, only, interested in my FT3 lab #s. Since T3 is fast acting and short lived in the body is there any reason I can't have my FT3 tested anytime and have an accurate read? Thanks!
I am on
NDT
- same dose last 5mos. & just recently added a smidge more. I am, only, interested in my FT3 lab #s. Since T3 is fast acting and short lived in the body is there any reason I can't have my FT3 tested anytime and have an accurate read? Thanks!
terebol
in
Thyroid UK
1 year ago
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Using Enzalutamide, Darolutamide, Apalutamide only.
I've seen a number of posters here and there who say they use one of the "mides" listed above with no ADT like Lupron, Eligard, Firmagan, or Orgovyx, etc. If so, did you begin that regimen after being on first level ADT for a while along with the 'mide," or did you start on the "mide" alone at the start
I've seen a number of posters here and there who say they use one of the "mides" listed above with no ADT like Lupron, Eligard, Firmagan, or Orgovyx, etc. If so, did you begin that regimen after being on first level ADT for a while along with the 'mide," or did you start on the "mide" alone at the start
dhccpa
in
Prostate Cancer Network
6 months ago
Studies re: PSA > 0.5% after RT
Can anyone interpret the gist of these studies? Correct me if I am wrong (and I sure hope to be) but from what I am gleaning, it seems that for those who have RT and a concurrent round of ADT: 1) Researchers and studies are showing that waiting 18 months to reach a post RT nadir isn't necessary to determine
Can anyone interpret the gist of these studies? Correct me if I am wrong (and I sure hope to be) but from what I am gleaning, it seems that for those who have RT and a concurrent round of ADT: 1) Researchers and studies are showing that waiting 18 months to reach a post RT nadir isn't necessary to determine
quietcorner
in
Advanced Prostate Cancer
6 months ago
6 Month Eligard
I got my results from PSA/PET last week, showing no metastatic activity anywhere, bones and lymph nodes clear. My last Gleason score was 4+3 in 1 sample, 3+3 in 2 more same side, but focus of intraductal cancer in 2 cores on other side. Last PSA 5.3 in February, stable between 5.0 and 5.8 last 2 years
I got my results from PSA/PET last week, showing no metastatic activity anywhere, bones and lymph nodes clear. My last Gleason score was 4+3 in 1 sample, 3+3 in 2 more same side, but focus of intraductal cancer in 2 cores on other side. Last PSA 5.3 in February, stable between 5.0 and 5.8 last 2 years
SherpaT
in
Prostate Cancer Network
6 months ago
3year Updates w/PSA Graph
Hi Everyone, I'd like to report my 3 year journey. Initial PSA 27 in 6/20. Diagnosed w/PC 10/20. Gleason score is 3+4 (high-risk). My T-stage is T2a/T2b. CT Scan showed no lymph node & Bone Scan showed some indication of met. PSMA/PET in 1/12/21 showed no met outside. Started ADT (Lupron
Hi Everyone, I'd like to report my 3 year journey. Initial PSA 27 in 6/20. Diagnosed w/PC 10/20. Gleason score is 3+4 (high-risk). My T-stage is T2a/T2b. CT Scan showed no lymph node & Bone Scan showed some indication of met. PSMA/PET in 1/12/21 showed no met outside. Started ADT (Lupron
brucesam
in
Advanced Prostate Cancer
6 months ago
Length of Treatment for Orgovyx (Relugolix) versus Lupron and other Longer Acting ADT drugs as Adjuvant to RT or Used for IADT?
I'm curious if anyone has had any discussion with their MO or Radiation Oncologist about having to take a longer course of Orgovyx compared to Lupron or other longer acting ADT drugs because Testosterone comes back so much quicker on Orgovyx? It would seem to me, 6 months of Orgovyx is like the equivalent
I'm curious if anyone has had any discussion with their MO or Radiation Oncologist about having to take a longer course of Orgovyx compared to Lupron or other longer acting ADT drugs because Testosterone comes back so much quicker on Orgovyx? It would seem to me, 6 months of Orgovyx is like the equivalent
jazj
in
Advanced Prostate Cancer
6 months ago
Private GP recommendation
Looking to try
NDT
(currently metavive) and have found a private GP from the thyroid UK list who is near to where I live. He is Dr David Eccleston, Sutton Coldfield West mids. I hope this is ok to name him? If anyone has experience of this GP could you PM please? Thanks all
Looking to try
NDT
(currently metavive) and have found a private GP from the thyroid UK list who is near to where I live. He is Dr David Eccleston, Sutton Coldfield West mids. I hope this is ok to name him? If anyone has experience of this GP could you PM please? Thanks all
Liam12
in
Thyroid UK
2 years ago
Decipher Results
I now know I’m in the 10% worst category for genomic results. 20% chance of Mets in 10 years 25% chance of death in 15. Not happy. It’s out of my hands. They will ADT me then prostate bed and lymph node radiation. I guess I kinda always knew. I’m assuming someone has determined these steps are required
I now know I’m in the 10% worst category for genomic results. 20% chance of Mets in 10 years 25% chance of death in 15. Not happy. It’s out of my hands. They will ADT me then prostate bed and lymph node radiation. I guess I kinda always knew. I’m assuming someone has determined these steps are required
Elbers123
in
Advanced Prostate Cancer
6 months ago
after iADT and recurrence: SATURN trial
Upshot. Intense short term ADT and radiation therapy for "oligorecurrence" after iADT https://www.sciencedirect.com/science/article/abs/pii/S0302283824000587 The reason you have to like it is that it should not require new drug development and trials etc. I wonder if it would be applicable to oligorecurrence
Upshot. Intense short term ADT and radiation therapy for "oligorecurrence" after iADT https://www.sciencedirect.com/science/article/abs/pii/S0302283824000587 The reason you have to like it is that it should not require new drug development and trials etc. I wonder if it would be applicable to oligorecurrence
Derf4223
in
Advanced Prostate Cancer
6 months ago
How to convince a GP to prescribe estradiol patches?
I've been busy with ADT for almost 5 years and one of the most insidious SE has always been hot flushes. I find them quite debilitating as, when they hit (and that's often), I'm briefly incapable to concentrate/perform any task. After reading about some of you guys experiences with estradiol patches
I've been busy with ADT for almost 5 years and one of the most insidious SE has always been hot flushes. I find them quite debilitating as, when they hit (and that's often), I'm briefly incapable to concentrate/perform any task. After reading about some of you guys experiences with estradiol patches
R1166
in
Advanced Prostate Cancer
6 months ago
Out of date meds
I have a whole box of tirosint and armour
NDT
that is all going to go out of date march 30th. I still have a whole two months left. Anyone know if this will still be ok? Really do not want to Chuck considering how much it cost.
I have a whole box of tirosint and armour
NDT
that is all going to go out of date march 30th. I still have a whole two months left. Anyone know if this will still be ok? Really do not want to Chuck considering how much it cost.
Ajva
in
Thyroid UK
2 years ago
Update #6 Clear Decks
It’s taken me about 5/6 weeks, but I have weaned down slowly from 2.5 grains
NDT
+ multiple supplements to nothing. Originally I’d planned to keep 1/2 a grain of
NDT
but I decided to clear it out entirely. Some symptoms have certainly been worsening, others have improved.
It’s taken me about 5/6 weeks, but I have weaned down slowly from 2.5 grains
NDT
+ multiple supplements to nothing. Originally I’d planned to keep 1/2 a grain of
NDT
but I decided to clear it out entirely. Some symptoms have certainly been worsening, others have improved.
Hidden
in
Thyroid UK
1 year ago
Chemo or no/not yet?
59 years old. Metastatic/high volume. PSA hit 366 before starting Abiraterone and Degarelix. Start Lupron next week. Negative on DNA test. Will see what PSA looks like next week after a month of ADT. My question chemo, no chemo or wait on chemo? Onco and Rad Onco both seemed to have a very soft attitude
59 years old. Metastatic/high volume. PSA hit 366 before starting Abiraterone and Degarelix. Start Lupron next week. Negative on DNA test. Will see what PSA looks like next week after a month of ADT. My question chemo, no chemo or wait on chemo? Onco and Rad Onco both seemed to have a very soft attitude
4tunate1
in
Advanced Prostate Cancer
7 months ago
Was there ever really a chance for a cure?
When I began the Stampede protocol 1 1/2 yrs ago, it was my understanding that two years of Zytiga/Prednisone and three years of Lupon with radiation to the pelvic area at the 7 mo - 1 yr mark gave a chance for a "cure" under my conditions (3+4 gleason, etc). Now, my non-medical view of things is convincing
When I began the Stampede protocol 1 1/2 yrs ago, it was my understanding that two years of Zytiga/Prednisone and three years of Lupon with radiation to the pelvic area at the 7 mo - 1 yr mark gave a chance for a "cure" under my conditions (3+4 gleason, etc). Now, my non-medical view of things is convincing
duxlubber
in
Advanced Prostate Cancer
7 months ago
Brain Fog or Dimentia?
Hey warriors! So how do you know if you have brain fog or the beginning of dementia? Is it possible to blame ADT and Zytiga? My husband has been on Ellegaard for five years and Zytiga for 2 1/2. Years, he seems to have a lot of memory issues lately, and I fear it’s only getting worse Any thoughts or
Hey warriors! So how do you know if you have brain fog or the beginning of dementia? Is it possible to blame ADT and Zytiga? My husband has been on Ellegaard for five years and Zytiga for 2 1/2. Years, he seems to have a lot of memory issues lately, and I fear it’s only getting worse Any thoughts or
Keeper70
in
Advanced Prostate Cancer
7 months ago
Weighing the pros and possible risks of treatment holiday.
I am looking for reliable articles (not too scientific please). We will be discussing w oncologist this week and again with his clinical trial people next month. My husband's only treatment has been 1st & 2nd generation hormone therapy (Eligard & Darolutamide) for 20 months. He reached >.1 nadar
I am looking for reliable articles (not too scientific please). We will be discussing w oncologist this week and again with his clinical trial people next month. My husband's only treatment has been 1st & 2nd generation hormone therapy (Eligard & Darolutamide) for 20 months. He reached >.1 nadar
Decktime
in
Advanced Prostate Cancer
7 months ago
PSA on the way up again
I am getting a little concerned about a increase in my PSA, and not just the increase, but also the increase in the rate of increase. Short history. Diagnosed March 2021 by MRI and biopsy Gleason 4 + 3, Stage T3B, ISUP 3 ADT (Zoladex) started June 2021 EBRT 60Gy in 20 fractions December 2021 Last
I am getting a little concerned about a increase in my PSA, and not just the increase, but also the increase in the rate of increase. Short history. Diagnosed March 2021 by MRI and biopsy Gleason 4 + 3, Stage T3B, ISUP 3 ADT (Zoladex) started June 2021 EBRT 60Gy in 20 fractions December 2021 Last
ParrotY
in
Prostate Cancer Network
7 months ago
Dutasteride Monotherapy is effective for Newly Diagnosed PCa men not on ADT
This plot shows men that either don't have PCa (Group A) or newly diagnosed men with PCa by biopsy (Group B). Neither group is on ADT. Dutasteride monotherapy (0.5 mg/day) causes an average drop in PSA of about 50% in both Groups, and an average drop of about 20% in prostate volume. In one man, his
This plot shows men that either don't have PCa (Group A) or newly diagnosed men with PCa by biopsy (Group B). Neither group is on ADT. Dutasteride monotherapy (0.5 mg/day) causes an average drop in PSA of about 50% in both Groups, and an average drop of about 20% in prostate volume. In one man, his
janebob99
in
Prostate Cancer Network
7 months ago
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