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Chemo options when Stage 4 Gleason 8
My surprise is because my doctors said that at my stage (4, Gleason 8, 4+4 with tiny non-painful
metastasis
to pelvic and lower abdomen area that are only visible on the Pet Scan) the only options were radiation or ADT. Neither surgery nor chemo were ever on the table for me.
My surprise is because my doctors said that at my stage (4, Gleason 8, 4+4 with tiny non-painful
metastasis
to pelvic and lower abdomen area that are only visible on the Pet Scan) the only options were radiation or ADT. Neither surgery nor chemo were ever on the table for me.
Mascouche
in
Advanced Prostate Cancer
3 years ago
Can high ALP indicate therapy before bone mets are confirmed?
Does anyone know if this can be considered a strong indication that I indeed have
metastasis
in bones? Mets in lymph nodes are already confirmed. I am on Firmagon/degarelix + Bicalutamid now.
Does anyone know if this can be considered a strong indication that I indeed have
metastasis
in bones? Mets in lymph nodes are already confirmed. I am on Firmagon/degarelix + Bicalutamid now.
Purple-Bike
in
Advanced Prostate Cancer
3 years ago
First scan on Xeloda
Tomorrow morning I have my first scan after starting Xeloda in October. I've only had one good scan since being diagnosed in February '19 (my first scan on Ibrance). I've shown progression each time. Everolimus did nothing. I'm afraid Xeloda isn't working as the ache under my rib cage which diminished
Tomorrow morning I have my first scan after starting Xeloda in October. I've only had one good scan since being diagnosed in February '19 (my first scan on Ibrance). I've shown progression each time. Everolimus did nothing. I'm afraid Xeloda isn't working as the ache under my rib cage which diminished
Arisgram
in
SHARE Metastatic Breast Cancer
3 years ago
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I take letrozole and Ibrance together
After dinner. I am 3 weeks on both and 2 weeks just letrozole. This sounds crazy but I feel better when on both together. Letrozole itself causes me more body aches , tired and mood changes , depressed , anxious. Has anyone else experienced this before ? I have MBC to my bones , kidney, spleen , lymph
After dinner. I am 3 weeks on both and 2 weeks just letrozole. This sounds crazy but I feel better when on both together. Letrozole itself causes me more body aches , tired and mood changes , depressed , anxious. Has anyone else experienced this before ? I have MBC to my bones , kidney, spleen , lymph
Kdst777
in
SHARE Metastatic Breast Cancer
3 years ago
Rising PSA but scan ok.
His ct scan report says that the
metastasis
has mostly remained the same or slightly gotten better. Not sure how long he is to continue chemo but shouldn’t it be lowering?? His side effects of chemo are not too bad. TIA for at input
His ct scan report says that the
metastasis
has mostly remained the same or slightly gotten better. Not sure how long he is to continue chemo but shouldn’t it be lowering?? His side effects of chemo are not too bad. TIA for at input
Weezer513
in
Advanced Prostate Cancer
3 years ago
Wow, 3 in a row
Then November had bone density scan which 2 years ago said osteopenia and lumbar spine said too involved in
metastasis
to give a rating, now says normal bone density and even lumbar spine has a normal rating. I'm still in shock from all the good news.
Then November had bone density scan which 2 years ago said osteopenia and lumbar spine said too involved in
metastasis
to give a rating, now says normal bone density and even lumbar spine has a normal rating. I'm still in shock from all the good news.
michael00
in
Advanced Prostate Cancer
3 years ago
Real Gleason 6 does not metastasize (?)
Increasing strong evidence that a "real" Gleason 6 is NOT cancerous e.g. not at risk for
metastasis
. Comments? I guess determining an accurate Gleason score is not so trivial.
Increasing strong evidence that a "real" Gleason 6 is NOT cancerous e.g. not at risk for
metastasis
. Comments? I guess determining an accurate Gleason score is not so trivial.
drmoose
in
Prostate Cancer Network
4 years ago
Xeloda
Hi Ladies I’ve been on Xeloda now since the beginning of November and had the dose reduced to 1000 mg twice a day due to my sore feet...these have improved but my hands are peeling a bit but manageable I take the tablets one week on one week off and have just finished a week off...I thought I would
Hi Ladies I’ve been on Xeloda now since the beginning of November and had the dose reduced to 1000 mg twice a day due to my sore feet...these have improved but my hands are peeling a bit but manageable I take the tablets one week on one week off and have just finished a week off...I thought I would
Barbteeth
in
SHARE Metastatic Breast Cancer
3 years ago
Bruceantin, an amoebicidal anti-malarial agent from a plant, Brucea antidysenterica identified as potential drug for castrate resistant PCa
In addition, BCT efficiently suppresses tumor growth and
metastasis
of CRPC cells.
In addition, BCT efficiently suppresses tumor growth and
metastasis
of CRPC cells.
Graham49
in
Advanced Prostate Cancer
3 years ago
Xeloda
hi all hope everyone is well has anyone on xeloda developed blurry vision? I have a lot of redness around my eyeballs for awhile but past few days my eyes are blurry and use natural tears every morning.
hi all hope everyone is well has anyone on xeloda developed blurry vision? I have a lot of redness around my eyeballs for awhile but past few days my eyes are blurry and use natural tears every morning.
Barb5
in
SHARE Metastatic Breast Cancer
3 years ago
Heading to India for LU 177
So I’m rolling the dice and hoping that all the treatments I’ve had so far has not diminished this antigen from being expressed heavily on my
metastasis
. 🤞🏼 Flights are now booked and really hoping this will work out like it has for others out there to calm this beast for a little while longer.
So I’m rolling the dice and hoping that all the treatments I’ve had so far has not diminished this antigen from being expressed heavily on my
metastasis
. 🤞🏼 Flights are now booked and really hoping this will work out like it has for others out there to calm this beast for a little while longer.
Cleodman
in
Advanced Prostate Cancer
3 years ago
PSA increase after docetaxel treatment
I was diagnosed in April this year with advanced PC with high volume
metastasis
(only in the bones). Unfortunately an alleged hernia turned out to be a fatal disease. PSA 1380, ALP 566. Started with Zoladex in May which led to a spectacular decrease (660 in June, 260 begin July).
I was diagnosed in April this year with advanced PC with high volume
metastasis
(only in the bones). Unfortunately an alleged hernia turned out to be a fatal disease. PSA 1380, ALP 566. Started with Zoladex in May which led to a spectacular decrease (660 in June, 260 begin July).
mjv222
in
Advanced Prostate Cancer
3 years ago
PSA from 0.15 to 2.42 in 12 months; but no metastasis?
Asking advice and thoughts on my situation. I'm 5 years post IMRT to prostate and pelvic LN in 2015. Original PCa diagnosis in 2012 with Gleason 9 (4+5), Stage 4 ('locally advanced', no mets). Three cycles of ADT (4-6 months each) from 2012-2016. From Aug 2019 to Aug 2020 PSA went from 0.15 to 2.42.
Asking advice and thoughts on my situation. I'm 5 years post IMRT to prostate and pelvic LN in 2015. Original PCa diagnosis in 2012 with Gleason 9 (4+5), Stage 4 ('locally advanced', no mets). Three cycles of ADT (4-6 months each) from 2012-2016. From Aug 2019 to Aug 2020 PSA went from 0.15 to 2.42.
novatimo
in
Advanced Prostate Cancer
3 years ago
Breast pain
I occasionally have breast pain after a double mastectomy, 8 chemo treatments and 30 radiation treatments. I am now on Ibrance and Femara. I also had 16 lymph nodes removed on the side which had the cancer. Is it common to experience breast pain and what causes it? Just had a PET scan with good results
I occasionally have breast pain after a double mastectomy, 8 chemo treatments and 30 radiation treatments. I am now on Ibrance and Femara. I also had 16 lymph nodes removed on the side which had the cancer. Is it common to experience breast pain and what causes it? Just had a PET scan with good results
JEY1
in
SHARE Metastatic Breast Cancer
3 years ago
Axumin PET scan with undetectable PSA
I had some moderate back and hip pain recently in my right hip, and my PCP sent me for a CT scan, the radiologist reading that I have prostate cancer mentioned "possible bone
metastasis
" for the same areas that showed degenerative bone changes in the first Axumin PET scan 2019.
I had some moderate back and hip pain recently in my right hip, and my PCP sent me for a CT scan, the radiologist reading that I have prostate cancer mentioned "possible bone
metastasis
" for the same areas that showed degenerative bone changes in the first Axumin PET scan 2019.
Ralph1966
in
Advanced Prostate Cancer
3 years ago
Progression on Ibrance and Fasoldex
I was diagnosed in June with MBC in rib and sternum. About 1cm. I’ve been doing faslodex and Ibrance. My two bone mests have decreased but scan showed on Wednesday a new 8mm tumor in my lu g. Not what I was expecting to hear. My doctor said he wants to continue he on same treatment and another scan in
I was diagnosed in June with MBC in rib and sternum. About 1cm. I’ve been doing faslodex and Ibrance. My two bone mests have decreased but scan showed on Wednesday a new 8mm tumor in my lu g. Not what I was expecting to hear. My doctor said he wants to continue he on same treatment and another scan in
Dogmomtocockers
in
SHARE Metastatic Breast Cancer
3 years ago
Clinical Trial Niraparib or XOFIGO
If he does not qualify for the Clinical Trial or if he chooses not to participate in that, the 2nd treatment proposed is Radium 223 (*Question here is; being that this drug goes directly to the bone, and that is where the
metastasis
seems to be at this time, would this be a better option at this time
If he does not qualify for the Clinical Trial or if he chooses not to participate in that, the 2nd treatment proposed is Radium 223 (*Question here is; being that this drug goes directly to the bone, and that is where the
metastasis
seems to be at this time, would this be a better option at this time
Doradart
in
Advanced Prostate Cancer
3 years ago
Vaccine Candidates of Interest--- pTVG-HP DNA Vaccine and pTVG-AR DNA vaccine-- Brothers with Different Targets
In another comparison with GM-CSF, there was no improvement in
metastasis
free survival, but some evidence that the vaccine had effect on micrometastatic bone disease resulting in the current trials listed below: https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/ptvg-hp-plasmid-dna-vaccine
In another comparison with GM-CSF, there was no improvement in
metastasis
free survival, but some evidence that the vaccine had effect on micrometastatic bone disease resulting in the current trials listed below: https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/ptvg-hp-plasmid-dna-vaccine
NPfisherman
in
Fight Prostate Cancer
3 years ago
PIK3CA mutation and Piqray with Faslodex (Fulvestrant)
Hello Ladies, I went to see my Onc Friday. I'm currently on iBrance and Faslodex but she said I tested positive for the PIK3CA mutation and she may put me on Piqray and Faslodex in the next several months. I just have one month under my belt currently with iBrance and Faslodex. I have little dots
Hello Ladies, I went to see my Onc Friday. I'm currently on iBrance and Faslodex but she said I tested positive for the PIK3CA mutation and she may put me on Piqray and Faslodex in the next several months. I just have one month under my belt currently with iBrance and Faslodex. I have little dots
Adele_Julia
in
SHARE Metastatic Breast Cancer
3 years ago
Headaches
Hello, this is the first time I've posted though I have followed this site for some time and find it very comforting. I was diagnosed two years ago with secondary breast cancer in the bones 30 years after my initial mastectomy. I am on Ibrance and Letrozole and am currently stable with manageable side
Hello, this is the first time I've posted though I have followed this site for some time and find it very comforting. I was diagnosed two years ago with secondary breast cancer in the bones 30 years after my initial mastectomy. I am on Ibrance and Letrozole and am currently stable with manageable side
Gwynhubhome
in
SHARE Metastatic Breast Cancer
3 years ago
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