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Lynparza
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Seeking advice from Lynparza, Rubraca or Zejula patients.
why was the medication paused/stopped and/or if you have had a recurrence since being on
Lynparza
?
why was the medication paused/stopped and/or if you have had a recurrence since being on
Lynparza
?
TinaTina2020
in
SHARE Ovarian Cancer Support
1 year ago
Blue Sky News - Prostate Cancer Foundation of Australia - April 2023
This has ensured thousands of men have benefitted from no-cost genetic test to determining eligibility for
Lynparza
which has been found to lower men’s risk of death by 37% compared to other forms of treatment.
This has ensured thousands of men have benefitted from no-cost genetic test to determining eligibility for
Lynparza
which has been found to lower men’s risk of death by 37% compared to other forms of treatment.
marnieg46
in
Fight Prostate Cancer
1 year ago
Recurrence symptoms
I've had to go off one of my PARPS (
Lynparza
) because of complications and I hate how every little thing is making me so crazy paranoid: every abdominal twinge, weird bathroom issue, fatigue, gurgling tummy, feeling of fullness...is is cancer? Or is it just everyday stuff?
I've had to go off one of my PARPS (
Lynparza
) because of complications and I hate how every little thing is making me so crazy paranoid: every abdominal twinge, weird bathroom issue, fatigue, gurgling tummy, feeling of fullness...is is cancer? Or is it just everyday stuff?
FlowerRose
in
My Ovacome
8 months ago
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Lynparza
Been on
Lynparza
for one month and PSA is going up -was told that it is not uncommon for PSA to rise before it falls again. Has anyone else had this experience? Thank you.
Been on
Lynparza
for one month and PSA is going up -was told that it is not uncommon for PSA to rise before it falls again. Has anyone else had this experience? Thank you.
Rustyboat
in
Advanced Prostate Cancer
1 year ago
Genetic counseling & testing
Also, has anyone gone off-label with
Lynparza
, without having the BRCA mutation, and how did that work out? Thank you for any feedback you can provide!
Also, has anyone gone off-label with
Lynparza
, without having the BRCA mutation, and how did that work out? Thank you for any feedback you can provide!
Skifanatic
in
Advanced Prostate Cancer
1 year ago
Ac-225 results and next steps
His Guardant 360 does show a CHEK 2 mutation which would make him eligible for
Lynparza
. He also has a high TMB of 14.35 which makes him eligible for Keytruda. He is also willing to try chemo, again, as he has always tolerated it well.
His Guardant 360 does show a CHEK 2 mutation which would make him eligible for
Lynparza
. He also has a high TMB of 14.35 which makes him eligible for Keytruda. He is also willing to try chemo, again, as he has always tolerated it well.
leebeth
in
Advanced Prostate Cancer
1 year ago
If Pluvicto fails…what next?
Dxed March ‘18, and has gone through the gamut of standard of care (Docetaxal, Jevtana, Ra223,
Lynparza
, ADT) and now Pluvicto. He had one round about 4 weeks ago. Bloodwork a few days after round 1 showed an increase in PSA, but significant decrease in Alk Phos.
Dxed March ‘18, and has gone through the gamut of standard of care (Docetaxal, Jevtana, Ra223,
Lynparza
, ADT) and now Pluvicto. He had one round about 4 weeks ago. Bloodwork a few days after round 1 showed an increase in PSA, but significant decrease in Alk Phos.
Nettie8200
in
Advanced Prostate Cancer
1 year ago
Seeking feedback on PSMA Scan results after 6 chemo treatments
analysis came back positive for ATM, which appears to qualify me for
Lynparza
for treatment at some point. Any thoughts and/or suggestions welcome! THANK YOU. IMPRESSION: Further improvement in size and intensity of uptake in multiple nodal and osseous metastases.
analysis came back positive for ATM, which appears to qualify me for
Lynparza
for treatment at some point. Any thoughts and/or suggestions welcome! THANK YOU. IMPRESSION: Further improvement in size and intensity of uptake in multiple nodal and osseous metastases.
Skifanatic
in
Advanced Prostate Cancer
1 year ago
Dad with Stage 4 PCa - Need some words of wisdom...again please!
A liquid biopsy was carried out last week, waiting on results for BRCA2 (to see if he qualifies for olaparib (
Lynparza
®).
A liquid biopsy was carried out last week, waiting on results for BRCA2 (to see if he qualifies for olaparib (
Lynparza
®).
kikinini
in
Advanced Prostate Cancer
8 months ago
Xofigo
Gleason 9, Brac 2, psa 3 down from 200 14 months ago .On
Lynparza
and Orgovx. Just finished radiation for painful L5 met---early discomfort at T11 metastatic site. Hematocrit 30, platelets borderline. I'm pushing for preemptive Xofigo and getting some pushback from MO and RO.
Gleason 9, Brac 2, psa 3 down from 200 14 months ago .On
Lynparza
and Orgovx. Just finished radiation for painful L5 met---early discomfort at T11 metastatic site. Hematocrit 30, platelets borderline. I'm pushing for preemptive Xofigo and getting some pushback from MO and RO.
nuc1111
in
Advanced Prostate Cancer
2 years ago
Cancer treatment wait times for returning UK citizen
We have gone through one recurrence and my partner is now on
Lynparza
, though we don't know if it's working yet. I have a question that I hope some of you in the UK can help answer. My partner is from Manchester and is a UK citizen. But she has been living in Hong Kong for the last 10 years.
We have gone through one recurrence and my partner is now on
Lynparza
, though we don't know if it's working yet. I have a question that I hope some of you in the UK can help answer. My partner is from Manchester and is a UK citizen. But she has been living in Hong Kong for the last 10 years.
Stuee01
in
My Ovacome
2 years ago
Stopping olaparib/lynparza
Hoping others can share their experiences. My mom was given the option to stop taking olaparib after 2 years because she is NED. She is BRCA negative. She decided she is going to stop. Of course, as her daughter, I am panicked because we have had 2 years with her that we were not expecting. But I
Hoping others can share their experiences. My mom was given the option to stop taking olaparib after 2 years because she is NED. She is BRCA negative. She decided she is going to stop. Of course, as her daughter, I am panicked because we have had 2 years with her that we were not expecting. But I
Blf0910
in
My Ovacome
2 years ago
NHS agrees to roll out Olaparib (Lynparza) April 2023.
The drug, olaparib (
Lynparza
®), targets cancers with mutations in the BRCA genes, and works by stopping cancer cells from being able to repair their DNA by blocking a molecule called PARP, which causes the cancerous cells to die.
The drug, olaparib (
Lynparza
®), targets cancers with mutations in the BRCA genes, and works by stopping cancer cells from being able to repair their DNA by blocking a molecule called PARP, which causes the cancerous cells to die.
Sailing-Todd
in
Advanced Prostate Cancer
1 year ago
Quality of life on Lynparza PARP inhibitor
After 6 rounds of chemo and debulking surgery, we're bring told that they recommend she go on
Lynparza
. Has anyone here been on it? How long and what are the side effects? We're curious about quality of life on the drug since it's something more long-term. Thank you!
After 6 rounds of chemo and debulking surgery, we're bring told that they recommend she go on
Lynparza
. Has anyone here been on it? How long and what are the side effects? We're curious about quality of life on the drug since it's something more long-term. Thank you!
HopeSeeker22
in
SHARE Ovarian Cancer Support
2 years ago
change of medications because of a severe drug reaction from taking zejula 100 mg
On November 23 of this month my oncologist will start me on
lynparza
250 am and 250 pm.
On November 23 of this month my oncologist will start me on
lynparza
250 am and 250 pm.
peppermentcandy
in
SHARE Ovarian Cancer Support
2 years ago
Abiraterone/enzalutamide+PARP inhibitor better than abiraterone/enzalutamide alone for mCRPC, even without BRCA+
By combining the PARP inhibitor (
Lynparza
(olaparib) or Talzenna (talazoparib)) with either abiraterone or enzalutamide, cancer progression was slowed, even in men who were BRCA-.
By combining the PARP inhibitor (
Lynparza
(olaparib) or Talzenna (talazoparib)) with either abiraterone or enzalutamide, cancer progression was slowed, even in men who were BRCA-.
Tall_Allen
in
Advanced Prostate Cancer
1 year ago
Sacrum tumor biopsy
F/U on my post about
Lynparza
on my hubby, suggesting biopsy prior to IMRT, but at 80 yrs old, worried about risks going through bone and side effects. Dx last year with pc with meths to bones, G9, Orch last year, been on Nubeqa, other mets stable and psa still at <0.1.
F/U on my post about
Lynparza
on my hubby, suggesting biopsy prior to IMRT, but at 80 yrs old, worried about risks going through bone and side effects. Dx last year with pc with meths to bones, G9, Orch last year, been on Nubeqa, other mets stable and psa still at <0.1.
Pops78
in
Advanced Prostate Cancer
2 years ago
Things don’t look good!!!
My husband has been on Zytiga,
Lynparza
, Keytruda Doxetaxel, Cabazitaxel as well as Carboplatin. Nothing really worked long term. He is Castrate resistant. He most recently had one treatment of Lu 177. His platelets never really bounced back since his first treatment.
My husband has been on Zytiga,
Lynparza
, Keytruda Doxetaxel, Cabazitaxel as well as Carboplatin. Nothing really worked long term. He is Castrate resistant. He most recently had one treatment of Lu 177. His platelets never really bounced back since his first treatment.
Fight11
in
Advanced Prostate Cancer
2 years ago
Genetics test has BRAC2 mutation
PSA rising from 0.7 to 1.2 in 3 months, Genetics test has BRAC2 mutation, MO asked to stop Zytiga/Prednisone (being on it for 3.5 years), will start Olaparib (
Lynparza
) next week, does any have experience with Oplaparib?
PSA rising from 0.7 to 1.2 in 3 months, Genetics test has BRAC2 mutation, MO asked to stop Zytiga/Prednisone (being on it for 3.5 years), will start Olaparib (
Lynparza
) next week, does any have experience with Oplaparib?
dasyluo
in
Advanced Prostate Cancer
1 year ago
CA15-3 jumped 2nd month on Lynparza
Hello to those on
Lynparza
. I started taking
Lynparza
1st August this year. After 4 weeks, my CA15-3 went down from 139 to 95. But my blood test result for CA15-3 says it climbed to 200. I would welcome any comments and ask those who have experienced this to please share their experience.
Hello to those on
Lynparza
. I started taking
Lynparza
1st August this year. After 4 weeks, my CA15-3 went down from 139 to 95. But my blood test result for CA15-3 says it climbed to 200. I would welcome any comments and ask those who have experienced this to please share their experience.
MyMiracle13
in
SHARE Metastatic Breast Cancer
2 years ago
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