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Subcutaneous combination therapy improves ‘good on’ time in Parkinson’s
Primary analyses from this phase 3 clinical trial of the investigational, subcutaneous infusion of levodopa/carbidopa (LD/CD) (ND0612) showed that treatment in doses of up to 720 mg/90 mg per day, supplemented with oral levodopa provided almost 2 additional hours per day of “Good On” time without troublesome
Primary analyses from this phase 3 clinical trial of the investigational, subcutaneous infusion of levodopa/carbidopa (LD/CD) (ND0612) showed that treatment in doses of up to 720 mg/90 mg per day, supplemented with oral levodopa provided almost 2 additional hours per day of “Good On” time without troublesome
Farooqji
in
Cure Parkinson's
8 days ago
Ultrasound result and am now panicking
Hi, I wonder if anyone could offer some words of wisdom, I had an ultrasound yesterday and the sonographer said I had some fat in my liver, nothing to worry about. A week for results to GP. Phone call today from receptionist for urgent bloods, in a week and appt with GP, in 2 weeks. Asked to speak to
Hi, I wonder if anyone could offer some words of wisdom, I had an ultrasound yesterday and the sonographer said I had some fat in my liver, nothing to worry about. A week for results to GP. Phone call today from receptionist for urgent bloods, in a week and appt with GP, in 2 weeks. Asked to speak to
Owlie
in
British Liver Trust
8 days ago
Low cortisol
rheumatologist referred me to endocrinologist as Cortisol levels low He booked me in for a synacthen test. Which I had 3 weeks ago. I havnt got an appointment with him till end of August. I contacted his secretary who spoke to him and he said that level was inadequate and to continue with 5 mg of
rheumatologist referred me to endocrinologist as Cortisol levels low He booked me in for a synacthen test. Which I had 3 weeks ago. I havnt got an appointment with him till end of August. I contacted his secretary who spoke to him and he said that level was inadequate and to continue with 5 mg of
Creamtea
in
PMRGCAuk
9 days ago
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update
Update on my post “What should I do”, thank you for all your helpful replies. I had my COVID Jab and no after effects from that. I am seeing the Surgery Nurse to have my leg dressed twice a week.The haematoma is slow to heal due to the blood thinning medication but Hopefully it will heal soon. I heard
Update on my post “What should I do”, thank you for all your helpful replies. I had my COVID Jab and no after effects from that. I am seeing the Surgery Nurse to have my leg dressed twice a week.The haematoma is slow to heal due to the blood thinning medication but Hopefully it will heal soon. I heard
Macas
in
PMRGCAuk
9 days ago
results
good morning, just to let use know I had my liver scan and got results early, so was told am now compensated from decompensated which is great and apperently have been for months because am not yellow and ascites have gone 🤷♀️ meld score down to 12, so all is good news, am done with google I honestly
good morning, just to let use know I had my liver scan and got results early, so was told am now compensated from decompensated which is great and apperently have been for months because am not yellow and ascites have gone 🤷♀️ meld score down to 12, so all is good news, am done with google I honestly
Kingbilly3
in
British Liver Trust
9 days ago
electric toothbrush, and Trigeminal Neuralgia
hello everyone, does anyone use an electric toothbrush and they also have trigeminal neuralgia?, I stopped using my electric toothbrush in fear of the pressure causing/triggering the pain. Now I feel as though my teeth are not as clean.
hello everyone, does anyone use an electric toothbrush and they also have trigeminal neuralgia?, I stopped using my electric toothbrush in fear of the pressure causing/triggering the pain. Now I feel as though my teeth are not as clean.
MSbeGone
in
My MSAA Community
9 days ago
North not South
Psa at dx 139. Orgovyx and Nubeqa dropped it to 62.93 Started Docetaxil #1 Psa 23.91 #2 Psa 11.41 #3 Psa 7.15 #4 Psa 4.15 #5 Psa 2.38 #6 Psa 1.66 MO wanted to continue to 8. I agreed . There was a 6 week delay before #7. I took a Psa test right before 7 and it had dropped to 0.841 pleasantly
Psa at dx 139. Orgovyx and Nubeqa dropped it to 62.93 Started Docetaxil #1 Psa 23.91 #2 Psa 11.41 #3 Psa 7.15 #4 Psa 4.15 #5 Psa 2.38 #6 Psa 1.66 MO wanted to continue to 8. I agreed . There was a 6 week delay before #7. I took a Psa test right before 7 and it had dropped to 0.841 pleasantly
APK3
in
Advanced Prostate Cancer
9 days ago
Gleason 6 Treatment options .
Has anyone experienced Monotherapy - LDR Brachytherapy , without , EBRT or ADT . for Grade1 ( Gleason Score 3+3=6 Prostate Cancer ? OR LDR With EBRT Only ?
Has anyone experienced Monotherapy - LDR Brachytherapy , without , EBRT or ADT . for Grade1 ( Gleason Score 3+3=6 Prostate Cancer ? OR LDR With EBRT Only ?
Conlig1940
in
Advanced Prostate Cancer
9 days ago
What about stiffness
I think some of you already know that mom has contractures post her accident and cant move much. Recently her PT said - get her some muscle relaxant and omg what a difference. But i cant give it everyday. Please advise what folks are doing for stiffness and muscular issues please. She does get a massage
I think some of you already know that mom has contractures post her accident and cant move much. Recently her PT said - get her some muscle relaxant and omg what a difference. But i cant give it everyday. Please advise what folks are doing for stiffness and muscular issues please. She does get a massage
mymomhaspd
in
Cure Parkinson's
10 days ago
ATP and NAD+ Deficiency in Parkinson’s Disease
Laurie Mischley authored... https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9961646/#abstract-a.l.b.stitle Results from this pilot study contribute to a growing body of evidence that PD is not a brain disease, but a systemic metabolic syndrome with disrupted cellular energetics and function in peripheral
Laurie Mischley authored... https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9961646/#abstract-a.l.b.stitle Results from this pilot study contribute to a growing body of evidence that PD is not a brain disease, but a systemic metabolic syndrome with disrupted cellular energetics and function in peripheral
JayPwP
in
Cure Parkinson's
10 days ago
Soy Lecithin protien powder ?
I am on a low calorie high protien diet, and have been using protien powder to supplement my diet. However I have become aware of articles saying that one of the ingredients ( Soy Lecithen ) is believed to interfere with thyroid hormone production ! What are people's thoughts on this, as I am very
I am on a low calorie high protien diet, and have been using protien powder to supplement my diet. However I have become aware of articles saying that one of the ingredients ( Soy Lecithen ) is believed to interfere with thyroid hormone production ! What are people's thoughts on this, as I am very
Bigsi
in
Thyroid UK
10 days ago
normal gamma-gt and cirrhosis?
hello, I went to the GP today to discuss concerns about drinking. I’ve cut down significantly but am concerned about having already done irreversible damage. Historically my results have always been normal (last blood test in March). She said that if gamma-gt is normal, cirrhosis is unlikely, but did
hello, I went to the GP today to discuss concerns about drinking. I’ve cut down significantly but am concerned about having already done irreversible damage. Historically my results have always been normal (last blood test in March). She said that if gamma-gt is normal, cirrhosis is unlikely, but did
Soph9987
in
British Liver Trust
10 days ago
can loading doses cause liver enzymes to go up
hello All, I received some blood work back and I noticed my liver enzymes are high alt and ast. I am injecting EOD now and on 6th week. just curious because thats the only thing that has changed since my last blood work is I am now doing injections not just oral liquid sublingual. thank you for any
hello All, I received some blood work back and I noticed my liver enzymes are high alt and ast. I am injecting EOD now and on 6th week. just curious because thats the only thing that has changed since my last blood work is I am now doing injections not just oral liquid sublingual. thank you for any
JesusMercy60
in
Pernicious Anaemia Society
10 days ago
Update on Treatment
In June 2023, a routine PSA test value turned out to be 4.6, did an MRI; Diagnosed with Prostate Cancer, Gleason Score 7 (3+4), biopsy said one core. (Details in my profile). Opted for Active Surveillance. But in Oct 2023, PSA level went to 6.1 and in Jan 2024 PSA went to 9.2 In March 2024, did another
In June 2023, a routine PSA test value turned out to be 4.6, did an MRI; Diagnosed with Prostate Cancer, Gleason Score 7 (3+4), biopsy said one core. (Details in my profile). Opted for Active Surveillance. But in Oct 2023, PSA level went to 6.1 and in Jan 2024 PSA went to 9.2 In March 2024, did another
Sushupthi
in
Advanced Prostate Cancer
10 days ago
raised AST (SGOT) levels and your history with CLL
when i was DX 7 years ago, my AST levels were at around 30. my oncologist hasn't said much about the fluctuations, which have gone up to 50 on occasion. so when i went to see my GP who worked in oncology in another country, told me that i have mild fatty liver, i was shocked as i was obviously unaware
when i was DX 7 years ago, my AST levels were at around 30. my oncologist hasn't said much about the fluctuations, which have gone up to 50 on occasion. so when i went to see my GP who worked in oncology in another country, told me that i have mild fatty liver, i was shocked as i was obviously unaware
ninap
in
CLL Support
10 days ago
worrying results but not yet diagnosed
hi all I had some blood tests for something unrelated which showed high creatinine and a low egfr. Then I had a urine test which showed high albumin levels. Last week I had an ultrasound which showed normal size kidneys but inflammation. Does all this mean I have kidney disease? My appt to see a
hi all I had some blood tests for something unrelated which showed high creatinine and a low egfr. Then I had a urine test which showed high albumin levels. Last week I had an ultrasound which showed normal size kidneys but inflammation. Does all this mean I have kidney disease? My appt to see a
Meagain24
in
Early CKD Support
11 days ago
Caffeine
I’m on 87.5mcg levo for now (have been prescribed 100mcg, but am increasing slowly) and I plan to test again in another couple of weeks with MMH to see how my levels are doing. Over the past two weeks I’ve felt really well and have been out and about more - walking, shopping, out for coffee (only ever
I’m on 87.5mcg levo for now (have been prescribed 100mcg, but am increasing slowly) and I plan to test again in another couple of weeks with MMH to see how my levels are doing. Over the past two weeks I’ve felt really well and have been out and about more - walking, shopping, out for coffee (only ever
JoJoloveschocolate
in
Thyroid UK
11 days ago
Looking for any Info for Recent PC Diagnosis
I’m a 62 year old, recently diagnosed with advanced prostate cancer. I’ve been on hormone therapy for 2 weeks and see my oncologist in a week. My PC seems to be aggressive and my PSA is off the charts 885! I would love any positive info I can get.
I’m a 62 year old, recently diagnosed with advanced prostate cancer. I’ve been on hormone therapy for 2 weeks and see my oncologist in a week. My PC seems to be aggressive and my PSA is off the charts 885! I would love any positive info I can get.
Iber
in
Advanced Prostate Cancer
12 days ago
Dosage question.
I was diagnosed with Graves and overactive thyroid forty four years ago. I had a thyroidectomy and started on synthetic thyroid hormone therapy. I’m 69 now and take 100 mcg of Levothyroxine daily, my TSH is 0.291, low. What dose should I be taking?
I was diagnosed with Graves and overactive thyroid forty four years ago. I had a thyroidectomy and started on synthetic thyroid hormone therapy. I’m 69 now and take 100 mcg of Levothyroxine daily, my TSH is 0.291, low. What dose should I be taking?
UndertheTuscanSun
in
Thyroid UK
12 days ago
Ascites
I’m going through the diagnosis process at the mo. Had CT scan last week. Follow up appointment isn’t until a week on Monday. I’m quite sure I’m suffering with ascites. Do I wait til that appointment to find out or should I call someone (consultant’s secretary or my own GP) to ask for it to be drained
I’m going through the diagnosis process at the mo. Had CT scan last week. Follow up appointment isn’t until a week on Monday. I’m quite sure I’m suffering with ascites. Do I wait til that appointment to find out or should I call someone (consultant’s secretary or my own GP) to ask for it to be drained
K-Bear88
in
My Ovacome
12 days ago
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