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SRBT and EXTEND trial
Does anybody have the full text of EXTEND trial results from June 2023? (my payment attempt is rejected and the tips on how to get a study without cost doesn´t work) https://pubmed.ncbi.nlm.nih.gov/37022702/ Addition of Metastasis-Directed Therapy to Intermittent Hormone Therapy for Oligometastatic
Does anybody have the full text of EXTEND trial results from June 2023? (my payment attempt is rejected and the tips on how to get a study without cost doesn´t work) https://pubmed.ncbi.nlm.nih.gov/37022702/ Addition of Metastasis-Directed Therapy to Intermittent Hormone Therapy for Oligometastatic
Purple-Bike
in
Advanced Prostate Cancer
5 months ago
Has anyone taken a non-medication route and seen an improvement in their osteoporosis through only supplements/diet/exercise?
Hello, I have osteoporosis and been advised to take medication - either HRT or Alendronate. However, I as an alternative wondered whether anyone who is not on medication has seen an improvement in their osteoporosis through only supplements/diet/exercise?
Hello, I have osteoporosis and been advised to take medication - either HRT or Alendronate. However, I as an alternative wondered whether anyone who is not on medication has seen an improvement in their osteoporosis through only supplements/diet/exercise?
Houseelf
in
Bone Health and Osteoporosis UK
5 months ago
What is the next step
I have one more Immunotherapy for my bladder cancer, so far all scan have shown no metastasis. Now I need to focus on my PC after more than a year of ignoring it. My PSA has been fluctuating and is now 0.65, doubling time is 16 months, I have not had ADT yet and my MO wants to just wait and watch. What
I have one more Immunotherapy for my bladder cancer, so far all scan have shown no metastasis. Now I need to focus on my PC after more than a year of ignoring it. My PSA has been fluctuating and is now 0.65, doubling time is 16 months, I have not had ADT yet and my MO wants to just wait and watch. What
old64horn
in
Advanced Prostate Cancer
5 months ago
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Follow up to "My trajectory after a 'vacation' and a new metastasis," and a new question
I though that the recommendation of the "tumor board" at Smilow Cancer Center in New Haven, CT, would be "doublet therapy" to treat the new metastasis that was found with a PET PSMA scan, (the second one that was found after my Lupron "vacation"; the first was treated with radiation--details of my case
I though that the recommendation of the "tumor board" at Smilow Cancer Center in New Haven, CT, would be "doublet therapy" to treat the new metastasis that was found with a PET PSMA scan, (the second one that was found after my Lupron "vacation"; the first was treated with radiation--details of my case
Istomin
in
Advanced Prostate Cancer
5 months ago
Low appetite
Hi, undiagnosed but strongly suspect hypo possibly Hashi and gathering info/signs etc. Started supplements for folate, vit d (with k) and b complex just about to start magnesium too. On HRT including DHEA. So, my appetite has been on the wane, probably since menopause and thyroid problems began.
Hi, undiagnosed but strongly suspect hypo possibly Hashi and gathering info/signs etc. Started supplements for folate, vit d (with k) and b complex just about to start magnesium too. On HRT including DHEA. So, my appetite has been on the wane, probably since menopause and thyroid problems began.
Fizzwhizz
in
Thyroid UK
5 months ago
Invitro study shows Delta Tocotrienol overcomes Docetaxel resistence in PCa
Necroptosis Induced by Delta-Tocotrienol Overcomes Docetaxel Chemoresistance in Prostate Cancer CellsMarina Montagnani Marelli, Giangiacomo Beretta, Roberta Manuela Moretti International Journal of Molecular Sciences 24 (5), 4923, 2023 Prostate cancer (PCa) represents the fifth cause of cancer death
Necroptosis Induced by Delta-Tocotrienol Overcomes Docetaxel Chemoresistance in Prostate Cancer CellsMarina Montagnani Marelli, Giangiacomo Beretta, Roberta Manuela Moretti International Journal of Molecular Sciences 24 (5), 4923, 2023 Prostate cancer (PCa) represents the fifth cause of cancer death
Graham49
in
Fight Prostate Cancer
10 months ago
Thank you 💕
To everyone who responded to me, a big thank you. It is 8.30am here and I am drinking tea with RLS already! Great. I am so sorry for all of you here - but it is so great to have people who understand and sympathise and also have great suggestions. So thank you all. Chris- there is oxygen therapy
To everyone who responded to me, a big thank you. It is 8.30am here and I am drinking tea with RLS already! Great. I am so sorry for all of you here - but it is so great to have people who understand and sympathise and also have great suggestions. So thank you all. Chris- there is oxygen therapy
Bowie4eva
in
Restless Legs Syndrome
1 year ago
ASCO 2023: AI-Derived Digital Pathology Biomarker Predicts Benefit of Long-Term ADT with Radiotherapy in Localized High-Risk Prostate Cancer
https://www.urotoday.com/conference-highlights/asco-2023/asco-2023-prostate-cancer/144902-asco-2023-development-and-validation-of-an-ai-derived-digital-pathology-based-biomarker-to-predict-benefit-of-long-term-androgen-deprivation-therapy-with-radiotherapy-in-men-with-localized-high-risk-prostate-cancer-across-multiple-phase-iii-nrg-rtog-trials.html
https://www.urotoday.com/conference-highlights/asco-2023/asco-2023-prostate-cancer/144902-asco-2023-development-and-validation-of-an-ai-derived-digital-pathology-based-biomarker-to-predict-benefit-of-long-term-androgen-deprivation-therapy-with-radiotherapy-in-men-with-localized-high-risk-prostate-cancer-across-multiple-phase-iii-nrg-rtog-trials.html
zeitgeistxx
in
Advanced Prostate Cancer
5 months ago
Short-term vs Long-Term ADT for High Risk Men
Here's a review of a recent presentation at ASCO 2023 by Artera.ai regarding the use of Artificial Intelligence analysis of biopsy slides to predict which high-risk men do or don't benefit from short-term ADT vs long-term ADT. Their findings are summarized here: [i]"Based on these results, it appears
Here's a review of a recent presentation at ASCO 2023 by Artera.ai regarding the use of Artificial Intelligence analysis of biopsy slides to predict which high-risk men do or don't benefit from short-term ADT vs long-term ADT. Their findings are summarized here: [i]"Based on these results, it appears
janebob99
in
Prostate Cancer Network
5 months ago
Newly diagnosed researching lifestyle changes
Hi there, Had a overall physical of everything which included PSA which was 6 in 2016 and didn't put any attention to it and ignored it, nobody I spoke with who saw the report said to do anything. No family history of prostate cancer that I know of. Now 7 years later age 64, PSA 18, Free PSA 11%
Hi there, Had a overall physical of everything which included PSA which was 6 in 2016 and didn't put any attention to it and ignored it, nobody I spoke with who saw the report said to do anything. No family history of prostate cancer that I know of. Now 7 years later age 64, PSA 18, Free PSA 11%
Nwdx
in
Advanced Prostate Cancer
4 months ago
Managing OAB after proton RT
Hello everyone, This 73 year old treated an unfavorable intermediate localized PCa with 28 fractions of proton radiation, completed on Dec. 15th. Completed a 4 months course of oral Orgovyx on Dec. 28th. The side effects of the ADT were hot flashes (tolerable) and loss of libido. The side effects
Hello everyone, This 73 year old treated an unfavorable intermediate localized PCa with 28 fractions of proton radiation, completed on Dec. 15th. Completed a 4 months course of oral Orgovyx on Dec. 28th. The side effects of the ADT were hot flashes (tolerable) and loss of libido. The side effects
old_reliable
in
Prostate Cancer Network
5 months ago
New Mama
Hi all, I'm new to the whole pregnancy world! I've been trying for a baby for over 7 years (was with an abusive partner at the time) but after being with my new partner for a few months I'm now expecting! The thing I want to ask is going to sound weird and no one seems to know what I mean or say that
Hi all, I'm new to the whole pregnancy world! I've been trying for a baby for over 7 years (was with an abusive partner at the time) but after being with my new partner for a few months I'm now expecting! The thing I want to ask is going to sound weird and no one seems to know what I mean or say that
KR2022
in
Pregnancy and Parenting Support
8 months ago
Will T return?
As I near the end of my 2 years of ADT (Lupron + Abi), I am curious if I should expect a return of Testosterone. I would love to regain my libido and endurance. But after 2 years, I don't know what to expect. My MO has been pretty vague about what to expect. Another issue is that I didn't have a
As I near the end of my 2 years of ADT (Lupron + Abi), I am curious if I should expect a return of Testosterone. I would love to regain my libido and endurance. But after 2 years, I don't know what to expect. My MO has been pretty vague about what to expect. Another issue is that I didn't have a
jmarsh
in
Advanced Prostate Cancer
5 months ago
Staring at my unopened bottle of Orgovyx
Well, D-day (or maybe O-day) has arrived (thank you FED-X). I'm about to do a swan dive into my battle against my PCa. After a week of searching for this stuff, my clinic found it in Louisville Kentucky at a pharmacy called Onco360. Not exactly a neighborhood corner market with me living on an island
Well, D-day (or maybe O-day) has arrived (thank you FED-X). I'm about to do a swan dive into my battle against my PCa. After a week of searching for this stuff, my clinic found it in Louisville Kentucky at a pharmacy called Onco360. Not exactly a neighborhood corner market with me living on an island
mababa
in
Advanced Prostate Cancer
4 months ago
PSA 6 months after RT
Here is a review of a presentationby Dr. Ravi at ASCO 2023, regarding measuring the PSA at 6 months post radiation treatment, for all risk groups. He found that the 6-month post-RT PSA was highly prognostic of 5- and 10-year rates of metastasis free survival (MFS), Overall Survival (OS), and prostate
Here is a review of a presentationby Dr. Ravi at ASCO 2023, regarding measuring the PSA at 6 months post radiation treatment, for all risk groups. He found that the 6-month post-RT PSA was highly prognostic of 5- and 10-year rates of metastasis free survival (MFS), Overall Survival (OS), and prostate
janebob99
in
Prostate Cancer Network
5 months ago
Testosterone was nearly back to normal, then dropped
I had a year of Lupron and Enzalutamide in 2022. Testosterone slowly came back to a high of about 240 in June and Sept 2023. Normal for me is around 350 - 375. Now this week T is down to 156. Is this sort of fluctuation normal? I had 6 months of ADT in connection with radiation for recurrent PCa
I had a year of Lupron and Enzalutamide in 2022. Testosterone slowly came back to a high of about 240 in June and Sept 2023. Normal for me is around 350 - 375. Now this week T is down to 156. Is this sort of fluctuation normal? I had 6 months of ADT in connection with radiation for recurrent PCa
Teddy28
in
Advanced Prostate Cancer
5 months ago
BONE DENSITY TEST IS BAD
I am 68 with low volume metastatic to hip bones. Nothing elsewhere, at this time. Had PSA of 125 last April, and oncologist put me on Relogolix and Darolutemide. That along with going to plant based diet and adding weights and HITT exercise 3-4x per week, has brought me down to < .006. that’s the
I am 68 with low volume metastatic to hip bones. Nothing elsewhere, at this time. Had PSA of 125 last April, and oncologist put me on Relogolix and Darolutemide. That along with going to plant based diet and adding weights and HITT exercise 3-4x per week, has brought me down to < .006. that’s the
JL1955
in
Advanced Prostate Cancer
6 months ago
Holding very low stable usPSA - 0.03X range for six years; no ADT, no chemo.
Eight years ago this month had RP after considerable investigation - nadir 0.050. Eleven months later had salvage RT; done at 0.10. Then after a year of pondering ADT and chemo, when my usPSA was back up to 0.10, I went to Europe for Ferrotran nano-MRI combined with Ga68 PSMA. The nanoMRI lite up
Eight years ago this month had RP after considerable investigation - nadir 0.050. Eleven months later had salvage RT; done at 0.10. Then after a year of pondering ADT and chemo, when my usPSA was back up to 0.10, I went to Europe for Ferrotran nano-MRI combined with Ga68 PSMA. The nanoMRI lite up
NanoMRI
in
Advanced Prostate Cancer
6 months ago
Full circle with this disease
Diagnosed 2017 PSA 105 started ADT, 6 rounds Docetaxel and radiation PSA drops to undetectable. Castrate resistant 2022 started Abiraterone and prednisone this failed after 3 months. Start Xgeva and Xofigo 2023. PSA back at 105 November 2023. Start 10 rounds of Docetaxel and PSA starts dropping again
Diagnosed 2017 PSA 105 started ADT, 6 rounds Docetaxel and radiation PSA drops to undetectable. Castrate resistant 2022 started Abiraterone and prednisone this failed after 3 months. Start Xgeva and Xofigo 2023. PSA back at 105 November 2023. Start 10 rounds of Docetaxel and PSA starts dropping again
Islandboy2021
in
Advanced Prostate Cancer
6 months ago
Blood test prep
Hi, Please can someone remind me what I need to stop taking before thyroid blood tests are carried out? I’m currently taking HRT transdermal oestrogen, DHEA tablets and progesterone tablets. I also started taking b vit complex, methylated folate, niacinimide, omega oils. I’m undiagnosed currently
Hi, Please can someone remind me what I need to stop taking before thyroid blood tests are carried out? I’m currently taking HRT transdermal oestrogen, DHEA tablets and progesterone tablets. I also started taking b vit complex, methylated folate, niacinimide, omega oils. I’m undiagnosed currently
Fizzwhizz
in
Thyroid UK
6 months ago
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