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What is role of hormonal therapy drug when taken with targeted therapy, eg Piqray or Ibrance?
I’ve been curious about this and wondering if anyone can explain. I want to better understand the role of the hormone therapy eg Faslodex when taken with targeted therapy such as Ibrance. Does it just reduce the amount of estrogen available to the cell and “lightens the load” on the targeted therapy?
I’ve been curious about this and wondering if anyone can explain. I want to better understand the role of the hormone therapy eg Faslodex when taken with targeted therapy such as Ibrance. Does it just reduce the amount of estrogen available to the cell and “lightens the load” on the targeted therapy?
HelenWi
in
SHARE Metastatic Breast Cancer
9 months ago
Now in hospice
I try to keep posts short and concise so I’ll try to keep this as brief as possible. We recently returned from a 2 week trip to SoCal to visit family and friends. I was hoping to post some nice QOL pics but in actuality the trip was fraught with difficulties. On return we had a visit with my husband
I try to keep posts short and concise so I’ll try to keep this as brief as possible. We recently returned from a 2 week trip to SoCal to visit family and friends. I was hoping to post some nice QOL pics but in actuality the trip was fraught with difficulties. On return we had a visit with my husband
Hidden
in
Advanced Prostate Cancer
9 months ago
Bladder dysfunction
in 2014, diagnosed Gleason 9, had Prostate surgery, cancer metastasized to pelvic region, did ADT, followed by 72 Proton blasts ( 37 to cavity-35 to pelvic) Two years ago, stricture surgery ( 80% urethra blockage- all good), had stricture surgery 3 weeks ago ( 25% blockage), but bladder stopped operating
in 2014, diagnosed Gleason 9, had Prostate surgery, cancer metastasized to pelvic region, did ADT, followed by 72 Proton blasts ( 37 to cavity-35 to pelvic) Two years ago, stricture surgery ( 80% urethra blockage- all good), had stricture surgery 3 weeks ago ( 25% blockage), but bladder stopped operating
Tkwham
in
Advanced Prostate Cancer
8 months ago
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Mirtazapine
I am taking Mirtazapine for anxiety and it has reduced my tremor quite a bit has anyone else found this?
I am taking Mirtazapine for anxiety and it has reduced my tremor quite a bit has anyone else found this?
percalona
in
Cure Parkinson's
5 months ago
Anyone turn down a stem cell transplant?
I have post ET MF. Currently I'm on Rux and getting monthly cycles of 5 aza. I don't need transfusions. Day to day I feel pretty good and can do most of what I want. The SCT was recommended because of the risk of progression to AML. I'm finding the decision making to get the SCT very difficult. My
I have post ET MF. Currently I'm on Rux and getting monthly cycles of 5 aza. I don't need transfusions. Day to day I feel pretty good and can do most of what I want. The SCT was recommended because of the risk of progression to AML. I'm finding the decision making to get the SCT very difficult. My
LongETinUS
in
MPN Voice
2 months ago
Hi. Mebeverine 200mg
Hi. I have been to the doctors again as really struggling again. My grandma has been diagnosed with lung cancer. And my symptoms have got worse. Im scared to eat as i need to work and colleagues making comments about my leaving due to my stomach. One day i only had two breakfast bars all day. Im having
Hi. I have been to the doctors again as really struggling again. My grandma has been diagnosed with lung cancer. And my symptoms have got worse. Im scared to eat as i need to work and colleagues making comments about my leaving due to my stomach. One day i only had two breakfast bars all day. Im having
Glutenlover
in
IBS Network
7 months ago
Reaching out to others with anxiety
I've lived with panic attacks and extreme anxiety since I was 18. They began when I left home to go to college. I've had decades of engaging in therapy, 12-step support groups and Recovery groups . The possibility of getting Covid has made me afraid to go to my 12-step groups in person. Being on-line
I've lived with panic attacks and extreme anxiety since I was 18. They began when I left home to go to college. I've had decades of engaging in therapy, 12-step support groups and Recovery groups . The possibility of getting Covid has made me afraid to go to my 12-step groups in person. Being on-line
Cowgirlcat84
in
Anxiety and Depression Support
5 months ago
Triplet cuties
Hello everyoneJust thought i'd show you these three cutie sets of triplet lambs born on a farm near Swindon this week. Hopefully they will give you all a boost as they are the first ones this year and a wonderful sign that Spring is coming. Hope your starting to see the first shoots in your gardens
Hello everyoneJust thought i'd show you these three cutie sets of triplet lambs born on a farm near Swindon this week. Hopefully they will give you all a boost as they are the first ones this year and a wonderful sign that Spring is coming. Hope your starting to see the first shoots in your gardens
misty14
in
LUPUS UK
5 months ago
ReelRecovery
I spent the last two days having a great time learning to fly fish and meet with a wide variety of men with and surviving cancer. The majority of the men had prostate cancer including advanced PC. Reel Recovery is a non profit organization whose mission is to improve the lives of men with cancer using
I spent the last two days having a great time learning to fly fish and meet with a wide variety of men with and surviving cancer. The majority of the men had prostate cancer including advanced PC. Reel Recovery is a non profit organization whose mission is to improve the lives of men with cancer using
spencoid2
in
Advanced Prostate Cancer
9 months ago
Neuroendocrine PCa
I posted awhile back that my PCa had progressed to high grade neuroendocrine carcinoma/small cell. I was treated with 4 rounds of atezolizumab/carboplatin/etoposide (chemotherapy and immunotherapy). A pet/CT scan shows it was effective, and I fared better than I expected going in, but definitely have
I posted awhile back that my PCa had progressed to high grade neuroendocrine carcinoma/small cell. I was treated with 4 rounds of atezolizumab/carboplatin/etoposide (chemotherapy and immunotherapy). A pet/CT scan shows it was effective, and I fared better than I expected going in, but definitely have
CharlieBC
in
Advanced Prostate Cancer
7 months ago
Jakafi
It has been two weeks that I am taking one pill a day. My hemoglobin today was an8 and last week was 11 ,has anyone had a drop like this and one week with just one pill? My doctor does not seem concerned because I’m feeling fine. I am rechecking next week and just nervous about it going lower
It has been two weeks that I am taking one pill a day. My hemoglobin today was an8 and last week was 11 ,has anyone had a drop like this and one week with just one pill? My doctor does not seem concerned because I’m feeling fine. I am rechecking next week and just nervous about it going lower
Ggrana3192
in
MPN Voice
9 months ago
cholecystectomy and cirrhosis
I’ve been advised that I need a cholecystectomy due to a polyp (9 x 6.5 mm). I have cirrhosis, but am fully compensated. I have been told that this operation can be very dangerous for someone with cirrhosis. Any help or advice please?
I’ve been advised that I need a cholecystectomy due to a polyp (9 x 6.5 mm). I have cirrhosis, but am fully compensated. I have been told that this operation can be very dangerous for someone with cirrhosis. Any help or advice please?
Turvy
in
British Liver Trust
5 months ago
RA and (periodontitis)gum disease 😱
morning all! So yesterday I went to the dentist because a large filling on a back tooth that I’ve had for many years fell out!when I got there the dentist popped a temporary one in and he did some X-rays he then said I have periodontitis gum disease 😱with bone loss he said to start with I need to have
morning all! So yesterday I went to the dentist because a large filling on a back tooth that I’ve had for many years fell out!when I got there the dentist popped a temporary one in and he did some X-rays he then said I have periodontitis gum disease 😱with bone loss he said to start with I need to have
Mybirthday1975
in
NRAS
5 months ago
On another subject …
Inspired bya post on another site I’d like to ask if anyone has high risk mutations and has NOT had a stem cell transplant and has NOT progressed to leukaemia? On the other site there were a few who had had MF for quite few years but with treatment were doing ok, and weren’t having transplants, for
Inspired bya post on another site I’d like to ask if anyone has high risk mutations and has NOT had a stem cell transplant and has NOT progressed to leukaemia? On the other site there were a few who had had MF for quite few years but with treatment were doing ok, and weren’t having transplants, for
lizzziep
in
MPN Voice
2 months ago
Has anyone experience of weekly rather than 3 weekly chemo sessions?
I have been diagnosed with Stage 3C ovarian cancer, after finding a smallish lump in my tum in July, which is now considerably larger (20cm). A ct scan showed abnormalites in several places, and this was followed by a laparoscopy to see the extent. I was told that I would be having 3 rounds of chemo
I have been diagnosed with Stage 3C ovarian cancer, after finding a smallish lump in my tum in July, which is now considerably larger (20cm). A ct scan showed abnormalites in several places, and this was followed by a laparoscopy to see the extent. I was told that I would be having 3 rounds of chemo
LovemyJackRussell
in
My Ovacome
9 months ago
Newly diagnosed seeking advice on surgical options
Hi, Recently diagnosed with S3 Ovarian Cancer and have been given a choice of primary debulking surgery followed by 6 rounds of chemo or interval debulking with the surgery in the middle of 6 rounds. Worried that PDS is more risky/ radical although I’ve been told that it wouldn’t be. Any advice/ experience
Hi, Recently diagnosed with S3 Ovarian Cancer and have been given a choice of primary debulking surgery followed by 6 rounds of chemo or interval debulking with the surgery in the middle of 6 rounds. Worried that PDS is more risky/ radical although I’ve been told that it wouldn’t be. Any advice/ experience
Bookclublover
in
My Ovacome
9 months ago
How can I support my brother?
My brother has advanced prostate cancer and has had surgery. New tests show it has metastasised in his hip. I want to be able to support him but also don't want to say the wrong thing or add to the stress he is already feeling. I would appreciate ANY advice ~ thank you so much.
My brother has advanced prostate cancer and has had surgery. New tests show it has metastasised in his hip. I want to be able to support him but also don't want to say the wrong thing or add to the stress he is already feeling. I would appreciate ANY advice ~ thank you so much.
wavedancers
in
Advanced Prostate Cancer
9 months ago
Ibs bam
I have ibs and bile acid malabsorption seen gastroenterologist on monday shes ruling out ibd and cronhs but i am still not convinced dont know of wat she said as still get loads of stomach pain specially before and after bowel movements she did say it could b scar tissue nerve damage or fibromalgyia
I have ibs and bile acid malabsorption seen gastroenterologist on monday shes ruling out ibd and cronhs but i am still not convinced dont know of wat she said as still get loads of stomach pain specially before and after bowel movements she did say it could b scar tissue nerve damage or fibromalgyia
Netbet22
in
IBS Network
7 months ago
How to Navigate Prostate Cancers With Actionable Mutations - Grand Rounds Highlights, MedPage Today - 09/26/2023
I'm travelling and using an unfamiliar tablet, so no cut and paste from these linked articles. Note the access to a PDF of the full Grand Rounds paper in the second linked article. It has a useful table and simplified treatment algorithm for those mCRPCa with actionable genetic mutations. [i]
A Roadmap
I'm travelling and using an unfamiliar tablet, so no cut and paste from these linked articles. Note the access to a PDF of the full Grand Rounds paper in the second linked article. It has a useful table and simplified treatment algorithm for those mCRPCa with actionable genetic mutations. [i]
A Roadmap
cujoe
in
Fight Prostate Cancer
9 months ago
Here we go again!
At my last hospital appointment in February I asked the consultant about his thoughts on masking still and he suggested that as we are having to live with it and the current variants are not serious for most people maybe relaxing with caution or words to that effect. I was happy with that and have enjoyed
At my last hospital appointment in February I asked the consultant about his thoughts on masking still and he suggested that as we are having to live with it and the current variants are not serious for most people maybe relaxing with caution or words to that effect. I was happy with that and have enjoyed
Jetliz
in
CLL Support
9 months ago
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