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Risk vs reward in clinical trials
Morning folks, I just finished reading my clinical protocol consent paperwork and don’t get the good warm feeling that the risk is worth the reward. This trial is through Sarah Cannon Research and involves a first in human investigational drug called TAK 280. It utilizes an approach already in clinical
Morning folks, I just finished reading my clinical protocol consent paperwork and don’t get the good warm feeling that the risk is worth the reward. This trial is through Sarah Cannon Research and involves a first in human investigational drug called TAK 280. It utilizes an approach already in clinical
Pmann
in
Advanced Prostate Cancer
8 months ago
What should I do - follow-ups not feeling thorough
Hi everyone, before I start my question I want to send out love to everyone on here and I really wish being well for everyone. I wish there wasn’t a load of experts on here because it means we are all in this. I was diagnosed in 2022 - they thought they would find ovarian but they were surprised to
Hi everyone, before I start my question I want to send out love to everyone on here and I really wish being well for everyone. I wish there wasn’t a load of experts on here because it means we are all in this. I was diagnosed in 2022 - they thought they would find ovarian but they were surprised to
OrdinarySoul
in
My Ovacome
8 months ago
groin pain with IBs
hello does anyone else experience left sided groin pain with their IBS? constipation mainly also get sciatica symptoms with the groin pain when get an attack. Pain also left side of belly button starts here then get the groin pain a few days later like a horrid stitch Makes me feel really anxious
hello does anyone else experience left sided groin pain with their IBS? constipation mainly also get sciatica symptoms with the groin pain when get an attack. Pain also left side of belly button starts here then get the groin pain a few days later like a horrid stitch Makes me feel really anxious
TINKER23
in
IBS Network
6 months ago
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Question about Celiac or NCGS...
I am wondering if anyone with NCGS gets neurological symptoms? I am also wondering about Celiac; if you test negative - does that mean you definitely are not Celiac? Last tests I got was when I was off gluten - blood and endoscope. So found nothing... Took a private finger prick one the other day, awaiting
I am wondering if anyone with NCGS gets neurological symptoms? I am also wondering about Celiac; if you test negative - does that mean you definitely are not Celiac? Last tests I got was when I was off gluten - blood and endoscope. So found nothing... Took a private finger prick one the other day, awaiting
Suffering_sunny
in
Gluten Free Guerrillas
6 months ago
Alendronic Acid
Been on A A for just over a year for improving bone met, now recently found that effects of acid and build up are giving me gas and stomach reactions that bowel are very loose others found this problem been Dr and oncology over matter
Been on A A for just over a year for improving bone met, now recently found that effects of acid and build up are giving me gas and stomach reactions that bowel are very loose others found this problem been Dr and oncology over matter
Chrisbaird
in
Advanced Prostate Cancer
6 months ago
Neuroendocrine prostate cancer could be restored to a state that responds to treatment
[i]It may be possible to restore drug-resistant neuroendocrine prostate cancer to a state that responds to treatment by depletion of a certain protein in cancer cells. A recent study published in Communications Biology by the University of Eastern Finland found that this protein, DPYSL5, is expressed
[i]It may be possible to restore drug-resistant neuroendocrine prostate cancer to a state that responds to treatment by depletion of a certain protein in cancer cells. A recent study published in Communications Biology by the University of Eastern Finland found that this protein, DPYSL5, is expressed
Don_1213
in
Advanced Prostate Cancer
8 months ago
hypothyroidism and stomach ulcers
I've just been diagnosed with stomach ulcers. They've sent a prescription through for a heavy dose of Proton pump inhibitors. But I have questions. For example, how do they know its excess stomach acid causing the ulcers? I thought or perhaps read somewhere that when you're hypothyroid (even if euthyroid
I've just been diagnosed with stomach ulcers. They've sent a prescription through for a heavy dose of Proton pump inhibitors. But I have questions. For example, how do they know its excess stomach acid causing the ulcers? I thought or perhaps read somewhere that when you're hypothyroid (even if euthyroid
ShatteredofLee
in
Thyroid UK
6 months ago
Stomach issues
Morning all, So I am just about at my wits end with chronic gastric reflux and chronic wind up and down without much smell. Sometimes I vomit with it, and now I can only eat jasmine rice and even struggle to get water down at the moment. My stomach feels like I have been beat up from the inside
Morning all, So I am just about at my wits end with chronic gastric reflux and chronic wind up and down without much smell. Sometimes I vomit with it, and now I can only eat jasmine rice and even struggle to get water down at the moment. My stomach feels like I have been beat up from the inside
M0wnt
in
LUPUS UK
6 months ago
treatment side effects vs cancer side effects
”Pain” vs “discomfort” in abdomen region following radiation and on Lupron- is it side effects or the cancer itself? Dad was diagnosed November 2023 and received radiation for 5 weeks that ended Jan 3rd. Started Lupron end of November. Cancer has spread to part of hip bone and pelvic lymph nodes.
”Pain” vs “discomfort” in abdomen region following radiation and on Lupron- is it side effects or the cancer itself? Dad was diagnosed November 2023 and received radiation for 5 weeks that ended Jan 3rd. Started Lupron end of November. Cancer has spread to part of hip bone and pelvic lymph nodes.
alysona828
in
Advanced Prostate Cancer
8 months ago
Has anyone else been diagnosed with hypercalciuria (excess calcium in urine) causing osteoporosis?
I've read a couple of osteoporosis forums and searched online and am not finding any information on hypercalciuria causing osteoporosis and its treatment (thiazide drugs which cause your kidneys to get rid of potassium and magnesium instead of calcium). I was diagnosed with osteoporosis (in my spine
I've read a couple of osteoporosis forums and searched online and am not finding any information on hypercalciuria causing osteoporosis and its treatment (thiazide drugs which cause your kidneys to get rid of potassium and magnesium instead of calcium). I was diagnosed with osteoporosis (in my spine
dw98611
in
Osteoporosis Support
2 years ago
anxiety / panic attacks
due to life , experiences, pains and disappointments I’m dealing now with severe anxiety disorder. It hits me anywhere. Anytime. Very uncomfortable. I’d like to exchange with people dealing with similar struggles
due to life , experiences, pains and disappointments I’m dealing now with severe anxiety disorder. It hits me anywhere. Anytime. Very uncomfortable. I’d like to exchange with people dealing with similar struggles
Lonelylioncub
in
Anxiety and Depression Support
2 months ago
Finding joy and peace in God and His beautiful creations
I know I'm preaching to the choir yet it's nice to have a listening understanding ear. Just had my 16th and 17th malignant skin cancer removed since receiving FCR in 2018 despite following all the recommendations My back pain that became radicular pain is due to some severe spinal stenosis and a large
I know I'm preaching to the choir yet it's nice to have a listening understanding ear. Just had my 16th and 17th malignant skin cancer removed since receiving FCR in 2018 despite following all the recommendations My back pain that became radicular pain is due to some severe spinal stenosis and a large
skipro
in
CLL Support
2 months ago
CHEMIST MISTAKE
On Monday I rung my pharmacy. I asked if they had 3 containers Synthroid 50mgs. I fekt that it. was the 100s and 25mg Synthroid giving me a tiny hard rash and I was going to try all 50s. The Dr sent the prescription straight to Chemist. I picked it up as it was ready 3 days later. I looked in the
On Monday I rung my pharmacy. I asked if they had 3 containers Synthroid 50mgs. I fekt that it. was the 100s and 25mg Synthroid giving me a tiny hard rash and I was going to try all 50s. The Dr sent the prescription straight to Chemist. I picked it up as it was ready 3 days later. I looked in the
JOY2THEWORLD49
in
Atrial Fibrillation Support
2 months ago
Wellbutrin, Gabapentin and Buspar?
I have a question, my doctor has me on as of now 150mg WellbutrinXr and 300mg 3 times a day Gabapentin. Next month he’s going to introduce Buspar into the equation to help with my anxiety symptoms that so far nothing has helped (hydroxyzine, propananol,lexapro). Is anyone else on this combo of meds?
I have a question, my doctor has me on as of now 150mg WellbutrinXr and 300mg 3 times a day Gabapentin. Next month he’s going to introduce Buspar into the equation to help with my anxiety symptoms that so far nothing has helped (hydroxyzine, propananol,lexapro). Is anyone else on this combo of meds?
TattoosMakeMeCool
in
Anxiety and Depression Support
2 months ago
anismus
I have chronic constipation. I think it is casued by various muscles not relaxing as the symptoms fit what I have read online. There are vaious names for this, anismus, dysssergenic defaecation and obstruced defaecation. I looked on this site and this is one of the groups that seems appropriate to post
I have chronic constipation. I think it is casued by various muscles not relaxing as the symptoms fit what I have read online. There are vaious names for this, anismus, dysssergenic defaecation and obstruced defaecation. I looked on this site and this is one of the groups that seems appropriate to post
Grassmower
in
IBS Network
6 months ago
Allograft
Just wanted to know if anyone knew anything about Allograft. My husband has just finished 2 yrs on ventaclax, all blood's good, and we expected to just go away and go back for blood's until maybe time for a different treatment, but was told they would like us to have a chat to a specialist about allograft
Just wanted to know if anyone knew anything about Allograft. My husband has just finished 2 yrs on ventaclax, all blood's good, and we expected to just go away and go back for blood's until maybe time for a different treatment, but was told they would like us to have a chat to a specialist about allograft
sue6741
in
CLL Support
2 months ago
BP numbers 3 month post Ablation
Hi all,Hope everyone is as well as they could be and wish you all a Sinus beat. So I'm 3 months more or less without Amioderone. Last 24 hrs I had to pop over A&E as I didn't like my BP numbers. My average jumped and had a couple of concerning results Device is trustworthy Omron I did some gardening
Hi all,Hope everyone is as well as they could be and wish you all a Sinus beat. So I'm 3 months more or less without Amioderone. Last 24 hrs I had to pop over A&E as I didn't like my BP numbers. My average jumped and had a couple of concerning results Device is trustworthy Omron I did some gardening
Quest4NSR
in
Atrial Fibrillation Support
2 months ago
Use hormone therapy or not with Proton therapy
Hi All, Question, doctor is suggesting hormone therapy along with proton therapy (28 treatments of radiation) my gleason score went from 3+3 to 4+3 last year and psa doubled from 10 to 20. I tried to get in to this study to determine the genetics of tumor but they said tumor sample was bad. should
Hi All, Question, doctor is suggesting hormone therapy along with proton therapy (28 treatments of radiation) my gleason score went from 3+3 to 4+3 last year and psa doubled from 10 to 20. I tried to get in to this study to determine the genetics of tumor but they said tumor sample was bad. should
jbsnv
in
Prostate Cancer Network
8 months ago
hello I have realy severe anxiety, realy struggling
hello iam suffering with realy bad anxiety, I have a heart rythym problem, but strong heart , but been told it’s ok , had it for13 yrs but never realy had symptoms until medication became to make me feel unwell , been given diazepam was ok first day but now I’m worried it’s giving me palpitations , my
hello iam suffering with realy bad anxiety, I have a heart rythym problem, but strong heart , but been told it’s ok , had it for13 yrs but never realy had symptoms until medication became to make me feel unwell , been given diazepam was ok first day but now I’m worried it’s giving me palpitations , my
Prosecco1997
in
Anxiety Support
2 months ago
Bad dumping incident?
Hi there. Just thought I’d reach out to see if anyone can relate to my situation. I’m over 5 months from three way Oesophageal Surgery. I was doing really well with eating and fitness levels. Then last Friday (after a Chinese takeaway which didn’t consist of more than some noodles and a bit of chicken
Hi there. Just thought I’d reach out to see if anyone can relate to my situation. I’m over 5 months from three way Oesophageal Surgery. I was doing really well with eating and fitness levels. Then last Friday (after a Chinese takeaway which didn’t consist of more than some noodles and a bit of chicken
Julieanne60
in
Oesophageal & Gastric Cancer
6 months ago
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