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Experiences with
Gonadotrophin releasing hormone (GnRH)
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hysterectomy advice
I’ve started
GNrH
injections (had 4) and saw the consultant today for a review and to discuss surgery. Surgery would be a complete hysterectomy but obviously there would be assistance from potential other teams (colorectal team). Has anyone had the surgery and if so any pros or cons?
I’ve started
GNrH
injections (had 4) and saw the consultant today for a review and to discuss surgery. Surgery would be a complete hysterectomy but obviously there would be assistance from potential other teams (colorectal team). Has anyone had the surgery and if so any pros or cons?
KTe23
in
Endometriosis UK
1 year ago
ADT duration
Is it 24 months from my starting Bicalutimide or 24 months from starting the
GnRH
Zoladex or 24 months from the end of radiotherapy? I’ve seen lots of discussion about 12, 18, 24 and 36 months but find it hard to find if these include pre ADT or post RT ADT.
Is it 24 months from my starting Bicalutimide or 24 months from starting the
GnRH
Zoladex or 24 months from the end of radiotherapy? I’ve seen lots of discussion about 12, 18, 24 and 36 months but find it hard to find if these include pre ADT or post RT ADT.
SimMartin
in
Advanced Prostate Cancer
1 year ago
Periods returning?
I have been on 2 different
GNRH
analogues for 2.5 years ish. I have decided to come off the injections as I can no longer tolerate the side effects. Especially joint pains. How long does it take for your periods to return? Will they be as bad as before? Thanks
I have been on 2 different
GNRH
analogues for 2.5 years ish. I have decided to come off the injections as I can no longer tolerate the side effects. Especially joint pains. How long does it take for your periods to return? Will they be as bad as before? Thanks
Awwy
in
Endometriosis UK
1 year ago
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Can you reject GNRH analogues? Consequences? Please help.
The surgeon called last week in response to some questions I had and made an offhand remark about having a shot for
GNRH
analogues. I had no idea what she was talking about. She made no mention of this during the pre-op consultation I had in March.
The surgeon called last week in response to some questions I had and made an offhand remark about having a shot for
GNRH
analogues. I had no idea what she was talking about. She made no mention of this during the pre-op consultation I had in March.
SeventeenNineteen
in
Endometriosis UK
1 year ago
Managing OHSS risk
I wasn't expecting it and it wasn't in the original plan, but I've been prescribed Cabergoline for 8 days, to start at the same time as the trigger, and will have to start clexane (blood thinners) and ganirelix (
gnrh
agonist) injections following egg retrieval.
I wasn't expecting it and it wasn't in the original plan, but I've been prescribed Cabergoline for 8 days, to start at the same time as the trigger, and will have to start clexane (blood thinners) and ganirelix (
gnrh
agonist) injections following egg retrieval.
SquishyBean
in
Fertility Network UK
5 months ago
Options?
Tried the Decapaptyl (
GNRH
) injections but bleed 24/7 with them?! Endo BGSE specialist has said there are no other options as hysterectomy isn’t considered until over 35 (I’m 27).
Tried the Decapaptyl (
GNRH
) injections but bleed 24/7 with them?! Endo BGSE specialist has said there are no other options as hysterectomy isn’t considered until over 35 (I’m 27).
Cats1311
in
Endometriosis UK
11 months ago
ASCO 2023 Poster: Androgen-deprivation therapy and risk of dementia in patients with prostate cancer:Clinical outcomes from real-world data.
The highest risk was witnessed with
GnRH
antagonists (degarelix), with a 92% increased risk. Interestingly, the increased risk of dementia in ADT groups was observed only among whites but not in African Americans.
The highest risk was witnessed with
GnRH
antagonists (degarelix), with a 92% increased risk. Interestingly, the increased risk of dementia in ADT groups was observed only among whites but not in African Americans.
rsgdmd
in
Advanced Prostate Cancer
1 year ago
goserelin and ACTH
I am wondering how and if
GnRH
medications like Zoladex impact the ACTH production and if the activity of the adrenal production of adrenal androgens feeds the prostate cancer cells independently of the LH / testosterone route.
I am wondering how and if
GnRH
medications like Zoladex impact the ACTH production and if the activity of the adrenal production of adrenal androgens feeds the prostate cancer cells independently of the LH / testosterone route.
SimMartin
in
Prostate Cancer Network
1 year ago
FSH going from 8 to 43 just in few weeks while preparing for a FET, is it temporary or menopause?
I went on 9 month Triptorelin injections(
GNRH
like lupron Zoladex etc) and 6 months on add back therapy and birth control pills after having a major surgery last year to remove Endometriosis, Adenomyosis, cysts adhesions etc.
I went on 9 month Triptorelin injections(
GNRH
like lupron Zoladex etc) and 6 months on add back therapy and birth control pills after having a major surgery last year to remove Endometriosis, Adenomyosis, cysts adhesions etc.
Bebe294
in
Fertility Network UK
1 year ago
2nd FET protocol for 4th embryo transfer
Due to my endometriosis the consultant suggested doing the frozen transfer using the long Day 21 FET HRT protocol, using
GnRH
analogue then estrogen medication and progesterone.
Due to my endometriosis the consultant suggested doing the frozen transfer using the long Day 21 FET HRT protocol, using
GnRH
analogue then estrogen medication and progesterone.
Naturewalks
in
Fertility Network UK
6 months ago
GNRH Injections and Fibroids
He has recommended the
GNRH
Analogue injections which will force the symptoms of the menopause early thus hopefully stopping my periods, shrinking the fibroids and reducing the pain. Has anyone had these injections and do they work?
He has recommended the
GNRH
Analogue injections which will force the symptoms of the menopause early thus hopefully stopping my periods, shrinking the fibroids and reducing the pain. Has anyone had these injections and do they work?
Melons70
in
Pelvic Pain Support Network
1 year ago
Fed up and tired
I have been in
GNRH
analogues for 2 years. I have made a decision to come off them now, as they initially told me to go on them when I was supposed to have been listed for surgery. I have just found out I wasn't listed until January 23 even though I had an exploration lap in Oct 22.
I have been in
GNRH
analogues for 2 years. I have made a decision to come off them now, as they initially told me to go on them when I was supposed to have been listed for surgery. I have just found out I wasn't listed until January 23 even though I had an exploration lap in Oct 22.
Awwy
in
Endometriosis UK
1 year ago
CVD & GnRH agonists/antagonists
Buserelin, Goserelin, Leuprorelin & Triptorelin are
GnRH
agonists, whereas Degarelix is a
GnRH
antagonist.
Buserelin, Goserelin, Leuprorelin & Triptorelin are
GnRH
agonists, whereas Degarelix is a
GnRH
antagonist.
pca2004
in
Fight Prostate Cancer
2 years ago
🔥 Hot Topic – Endometriosis and Menopause
It can also occur surgically following removal of ovaries and medically, as a side effect of hormone treatments such as
GnRH
analogues. Unlike surgical or natural menopause, a medical menopause is temporary and reverses when hormone treatments are stopped.
It can also occur surgically following removal of ovaries and medically, as a side effect of hormone treatments such as
GnRH
analogues. Unlike surgical or natural menopause, a medical menopause is temporary and reverses when hormone treatments are stopped.
Lynne_support
Endometriosis UK
in
Endometriosis UK
1 year ago
Coming off GNRH analogues
Hi, I have been on prostrap and then zoladex for the past 2.5 years. This was to help with pain which it did initially and i have been waiting for so long for an op. One year ago my consultant said persevere bit longer. Its only licensed for a 6 months and I'm concerned that I'm doing more damage
Hi, I have been on prostrap and then zoladex for the past 2.5 years. This was to help with pain which it did initially and i have been waiting for so long for an op. One year ago my consultant said persevere bit longer. Its only licensed for a 6 months and I'm concerned that I'm doing more damage
Awwy
in
Endometriosis UK
2 years ago
Employer not being supportive about endometriosis / invasion of privacy
I have just finished 6 months of a medically induced menopause (
GNRH
injections - which were awful in terms of side effects) and had another operation 2 weeks ago. I work in investment banking, very high pressure job and really long hours.
I have just finished 6 months of a medically induced menopause (
GNRH
injections - which were awful in terms of side effects) and had another operation 2 weeks ago. I work in investment banking, very high pressure job and really long hours.
BlueMorpho13
in
Endometriosis UK
1 year ago
Nonexistent Periods
I had a
GNRH
injection in July and still haven’t had a period, is this normal? I did have my endometriosis surgery in late November, but expected my periods to be back by now?
I had a
GNRH
injection in July and still haven’t had a period, is this normal? I did have my endometriosis surgery in late November, but expected my periods to be back by now?
Aardvarks
in
Endometriosis UK
2 years ago
Zoladex (GnRH agonist) + simultaneous HRT - help!
- Is prescribing HRT add-back ONLY after laparoscopy then norm when using
GnRH
agonists? - Was I even prescribed the correct oral HRT? I am haunted by a memory of a clinician at the gynae dept saying "Oh no, they put you on the wrong one!".
- Is prescribing HRT add-back ONLY after laparoscopy then norm when using
GnRH
agonists? - Was I even prescribed the correct oral HRT? I am haunted by a memory of a clinician at the gynae dept saying "Oh no, they put you on the wrong one!".
hayley_annette
in
Endometriosis UK
1 year ago
Should I go on Prostap/Zoladex?!
The surgeon said this was quiet bad and wants to put me on
GnRH
injections. Now my symptoms aren’t too bad (I started the mini pill a few months ago) and I’m lucky that at the moment they are fairly manageable so I don’t feel like I need intervention for pain relief.
The surgeon said this was quiet bad and wants to put me on
GnRH
injections. Now my symptoms aren’t too bad (I started the mini pill a few months ago) and I’m lucky that at the moment they are fairly manageable so I don’t feel like I need intervention for pain relief.
Louisehart1995
in
Endometriosis UK
2 years ago
Question About GNRH Injections
Hi all, I had a
GNRH
injection back in July and haven’t had a period since… is this normal? Feels like a very long time!
Hi all, I had a
GNRH
injection back in July and haven’t had a period since… is this normal? Feels like a very long time!
Aardvarks
in
Endometriosis UK
2 years ago
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