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PSA slightly rose after 8 months undetectable
I am 57 and on ADT (Firmagon+Zytiga+Prednisone) after surgery in 2022 and 39 sessions of RT in 2023 (Jan Feb). Till now I has been undetectable but at November my bloodwork showed PSA risen to 0.04. Should I be concerned or could it be just random fluctuation? Thanks for your reactions.
I am 57 and on ADT (Firmagon+Zytiga+Prednisone) after surgery in 2022 and 39 sessions of RT in 2023 (Jan Feb). Till now I has been undetectable but at November my bloodwork showed PSA risen to 0.04. Should I be concerned or could it be just random fluctuation? Thanks for your reactions.
noasim
in
Advanced Prostate Cancer
7 months ago
Dizziness from Zytiga/prednisone?
my MO tried something out of the ordinary - let me have a 'vacation' from ADT for a short while, even though i am Castrate -resistant. he was hoping we coudl keep PSA down while my Testosterone recovered, to see if that woudl make me feel better. to use his words, i have 'complained bitterly of the
my MO tried something out of the ordinary - let me have a 'vacation' from ADT for a short while, even though i am Castrate -resistant. he was hoping we coudl keep PSA down while my Testosterone recovered, to see if that woudl make me feel better. to use his words, i have 'complained bitterly of the
Tonwantonga
in
Advanced Prostate Cancer
7 months ago
Dual Action Hormone Therapy Targeting Two Parts of Androgen Receptor for mCRPC
Phase I/II trial of masofaniten combined with enzalutamide, a novel hormonal therapy for mCRPC. Masofaniten, a first-in-class N-terminal ligand antagonist for the androgen receptor, shows promise in overcoming resistance to current hormonal therapies. Hopefully a new weapon for us!
Phase I/II trial of masofaniten combined with enzalutamide, a novel hormonal therapy for mCRPC. Masofaniten, a first-in-class N-terminal ligand antagonist for the androgen receptor, shows promise in overcoming resistance to current hormonal therapies. Hopefully a new weapon for us!
Maxone73
in
Advanced Prostate Cancer
7 months ago
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Anyone tried cabazitaxel (Jevtana) monotherapy?
If you've tried cabazitaxel [u]
without
[/u] ADT, I would appreciate hearing about your side effects and effectiveness. I'm currently in excellent shape at age 72. Previously I tolerated docetaxel (which along with radiation of abdominal lymph nodes helped me return to undetectable PSA for 4+ years
If you've tried cabazitaxel [u]
without
[/u] ADT, I would appreciate hearing about your side effects and effectiveness. I'm currently in excellent shape at age 72. Previously I tolerated docetaxel (which along with radiation of abdominal lymph nodes helped me return to undetectable PSA for 4+ years
ron_bucher
in
Advanced Prostate Cancer
8 months ago
I have questions about Tamoxifen, aka Hormonal Therapy
Hello all, & blessed wishes during the Holiday Season. 🎄 I must admit I haven't been on here for a while, but I hope someone can give me some answers. I was diagnosed with Clear Cell Ovarian Cancer stage 4 in 2021. I have had 6 rounds of Chemo, & a total hysterectomy. I've been doing Avastin since
Hello all, & blessed wishes during the Holiday Season. 🎄 I must admit I haven't been on here for a while, but I hope someone can give me some answers. I was diagnosed with Clear Cell Ovarian Cancer stage 4 in 2021. I have had 6 rounds of Chemo, & a total hysterectomy. I've been doing Avastin since
gta03
in
SHARE Ovarian Cancer Support
8 months ago
Ovaries or no Ovaries
I'm 46 next week and have recently been diagnosed with a large fibroid approx 15cm x 10cm and also an ovarian cyst. Consultant has recommended an hysterectomy as I'm also having severe bleeding during my period and am very anaemic. Hysterectomy is also being recommended as my mother had breast cancer
I'm 46 next week and have recently been diagnosed with a large fibroid approx 15cm x 10cm and also an ovarian cyst. Consultant has recommended an hysterectomy as I'm also having severe bleeding during my period and am very anaemic. Hysterectomy is also being recommended as my mother had breast cancer
Pizzame
in
Pelvic Pain Support Network
8 months ago
Creatine?
I have a new personal trainer who I am using to help build and maintain muscle mass. I am not yet on ADT (TBD), but I want to have good habits for strength training if indeed I end up going that way. He mentioned recently that he might recommend creatine to me. I did some brief research and it seems
I have a new personal trainer who I am using to help build and maintain muscle mass. I am not yet on ADT (TBD), but I want to have good habits for strength training if indeed I end up going that way. He mentioned recently that he might recommend creatine to me. I did some brief research and it seems
MakeItRainbows
in
Advanced Prostate Cancer
8 months ago
Newly diagnosed
Hiya all I'm 46 and just been diagnosed with endometriosis. I've always had bad periods and have IBS so I have always put everything down to that. However in April this year I noticed how much worse it had become and went to see my GP.... I had scan in September where they could see they endometriosis
Hiya all I'm 46 and just been diagnosed with endometriosis. I've always had bad periods and have IBS so I have always put everything down to that. However in April this year I noticed how much worse it had become and went to see my GP.... I had scan in September where they could see they endometriosis
Sunshinecab
in
Endometriosis UK
8 months ago
Studies help explain why some prostate cancers become resistant to hormone therapy
https://www.sciencedaily.com/releases/2023/12/231204135037.htm
https://www.sciencedaily.com/releases/2023/12/231204135037.htm
zeitgeistxx
in
Advanced Prostate Cancer
8 months ago
stopping HRT patches
hello, I hope this is not an insensitive question. I’m waiting for a date for a colonoscopy and a gyne referral following 10 months of [i]malaise [/i]with cancer flag bloods in February and ongoing symptoms of bloating, spotting, RHS side pelvic sharp stabbing pain, period like pain (61) and back ache
hello, I hope this is not an insensitive question. I’m waiting for a date for a colonoscopy and a gyne referral following 10 months of [i]malaise [/i]with cancer flag bloods in February and ongoing symptoms of bloating, spotting, RHS side pelvic sharp stabbing pain, period like pain (61) and back ache
Stills
in
My Ovacome
8 months ago
PSA rise soon after surgery!
Writing regarding my dad. Worried and dont get any answers / just wait and see approach from medical team :( Dad 63 years old now, was diagnosed with prostate cancer october 2022. 2 small tumors 5x3 mm was shown on MR, no spread shown there. Biopsy showed gleason 3+4 ( 4 was 50%) Ralp surgery robotic
Writing regarding my dad. Worried and dont get any answers / just wait and see approach from medical team :( Dad 63 years old now, was diagnosed with prostate cancer october 2022. 2 small tumors 5x3 mm was shown on MR, no spread shown there. Biopsy showed gleason 3+4 ( 4 was 50%) Ralp surgery robotic
Daddysgirl83
in
Advanced Prostate Cancer
11 months ago
Psa rise soon after surgery, help!
Writing regarding my dad. Worried and dont get any answers / just wait and see approach from medical team :( Dad 63 years old now, was diagnosed with prostate cancer october 2022. 2 small tumors 5x3 mm was shown on MR, no spread shown there. Biopsy showed gleason 3+4 ( 4 was 40%). Ralp surgery robotic
Writing regarding my dad. Worried and dont get any answers / just wait and see approach from medical team :( Dad 63 years old now, was diagnosed with prostate cancer october 2022. 2 small tumors 5x3 mm was shown on MR, no spread shown there. Biopsy showed gleason 3+4 ( 4 was 40%). Ralp surgery robotic
Daddysgirl83
in
Fight Prostate Cancer
11 months ago
Stuck. Help Plz.
Hi, thanks for all the info here. I’ve been reading for hours, think I’ve tried to absorb too much too quickly as my brain feels like it’s going to pop! I’ve been feeling nauseous with low pain headaches for a month so had a GP apt last week. Bloods were done and all appears normal apart from thyroid
Hi, thanks for all the info here. I’ve been reading for hours, think I’ve tried to absorb too much too quickly as my brain feels like it’s going to pop! I’ve been feeling nauseous with low pain headaches for a month so had a GP apt last week. Bloods were done and all appears normal apart from thyroid
Hidden
in
Thyroid UK
8 months ago
Does ADT work for Gleason 9?
About to start ADT for Gleason 9 (5+4) for locally advanced prostate cancer, followed by IMRT in 1-2 months. (Plan to ask about HDR boost). PSMA Pet negative for spread but MO had another radiologist look at initial prostate MRI suggests extracapsular extension along neurovascular bundle with possible
About to start ADT for Gleason 9 (5+4) for locally advanced prostate cancer, followed by IMRT in 1-2 months. (Plan to ask about HDR boost). PSMA Pet negative for spread but MO had another radiologist look at initial prostate MRI suggests extracapsular extension along neurovascular bundle with possible
Hope49823
in
Advanced Prostate Cancer
7 months ago
What is role of hormonal therapy drug when taken with targeted therapy, eg Piqray or Ibrance?
I’ve been curious about this and wondering if anyone can explain. I want to better understand the role of the hormone therapy eg Faslodex when taken with targeted therapy such as Ibrance. Does it just reduce the amount of estrogen available to the cell and “lightens the load” on the targeted therapy?
I’ve been curious about this and wondering if anyone can explain. I want to better understand the role of the hormone therapy eg Faslodex when taken with targeted therapy such as Ibrance. Does it just reduce the amount of estrogen available to the cell and “lightens the load” on the targeted therapy?
HelenWi
in
SHARE Metastatic Breast Cancer
10 months ago
Advice about recent NDT thyroid blood tests and high SHBG
Hi there! Is there any connection between high SHBG and taking NDT thyroid medication? I've been feeling better than ever on my Erfa thyroid medication and I don't feel over medicated at all, but I had high SHBG. My estradiol also seems high. I've read that one reason for high SHBG can be hyperthyroidism
Hi there! Is there any connection between high SHBG and taking NDT thyroid medication? I've been feeling better than ever on my Erfa thyroid medication and I don't feel over medicated at all, but I had high SHBG. My estradiol also seems high. I've read that one reason for high SHBG can be hyperthyroidism
RatherBeSleeping
in
Thyroid UK
8 months ago
Break from ADT or not?
Hi everyone, my Dad was recommended 18-24 months of Lupron/Zytiga/Prednisone after Radiation Therapy. We reached that time and MO said that is up to my Dad if he wants to continue the treatment or not. Lately my dad had high blood pressure over 200 and he ended up in ER, but now the blood pressure is
Hi everyone, my Dad was recommended 18-24 months of Lupron/Zytiga/Prednisone after Radiation Therapy. We reached that time and MO said that is up to my Dad if he wants to continue the treatment or not. Lately my dad had high blood pressure over 200 and he ended up in ER, but now the blood pressure is
Simonapo
in
Advanced Prostate Cancer
8 months ago
Blood Pressure experience and views sought
Hi allI have been feeling ropey,v lethargic and a bit slow for a few months now, despite increase in Levothyroxine. I had attributed this to constant blood loss(months) following HRT which didn't suit me,however this stopped 2 months ago. Previous blood tests showed haemoglobin on the low side so have
Hi allI have been feeling ropey,v lethargic and a bit slow for a few months now, despite increase in Levothyroxine. I had attributed this to constant blood loss(months) following HRT which didn't suit me,however this stopped 2 months ago. Previous blood tests showed haemoglobin on the low side so have
Pebble23
in
Thyroid UK
8 months ago
methotrexate
I am currently on hydroxychloroquine and my doctor wants me to move to Methotrexate . I am stil getting hand pain and foot pain ect on the hydroxy.... The side effects of all these drugs terrifies me.. Anyone on Methotrexate and like it? Do you have more energy? Do you drink alcohol...Hair falling out
I am currently on hydroxychloroquine and my doctor wants me to move to Methotrexate . I am stil getting hand pain and foot pain ect on the hydroxy.... The side effects of all these drugs terrifies me.. Anyone on Methotrexate and like it? Do you have more energy? Do you drink alcohol...Hair falling out
tresa56
in
NRAS
9 months ago
Favorite RA drug? I have so much anxiety about trying a new one
I am currently on hydroxychloroquine and my doctor wants me to move to Methotrexate . I am stil getting hand pain and foot pain ect on the hydroxy.... The side effects of all these drugs terrifies me.. Anyone on Methotrexate and like it? Do you have more energy? Do you drink alcohol...Hair falling
I am currently on hydroxychloroquine and my doctor wants me to move to Methotrexate . I am stil getting hand pain and foot pain ect on the hydroxy.... The side effects of all these drugs terrifies me.. Anyone on Methotrexate and like it? Do you have more energy? Do you drink alcohol...Hair falling
tresa56
in
FieryBones - RA Community
9 months ago
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