Experiences with

Fibrinogen

Prothrombin time ratio 1 ratio ( 0.8 - 1.1) APPT ratio 1.4 ratio ( 0.85 - 1.15) Fibrinogen level 2.8 g/ l ( 1.6- 4.8)

Fibrinogen Activity or Fibrinogen antigen plus 5. CBC(complete metabolic profile) Do these tests sound appropriate as a baseline? Especially since I'm an avid Xarelto blood thinner med taker since Feb 14th.

Everything was ok or within normal parameters, however his Derived Fibrinogen level was 5.75 g/L (2.0 - 5.3) Above high reference limit. His serum prostate specific antigen level was 0.31 ug/L (0.0 - 3.0), which appears normal. I know nothing about Fibrinogen in fact I have never heard of it.

I got an mri that came out ok and blood work that showed low vit d, increased fibrinogen and lazy thyroid( tsh 5,79). Now i repetead a tsh, t3, rt3, t4, tgb blood work and they came back between normal range.( Tsh 3,57).My d vitamin went from 15 to now 77 ng wich is a bit over the limit.

Hi, had a punch skin biopsy done on my arm few months ago and it says “direct immunoflourescence shows granular deposition of IgM at the dermo-epidermal junction, together with fibrinogen in occasional dermal vessels”. Says is non diagnostic but suggests connective tissue disease.

(Wikipedia [1]) We want fibrinogen to low, albeit in the 'normal' range (IMO).

FFP alone is unlikely to be sufficient to improve fibrinogen levels (4 units raising the fibrinogen by approximately 1 g/L in an adult).

.-3-sedrate-fibrinogen-il-6-tnfalpha.

Severe covid-19 infection is associated with very high levels of inflammatory cytokines, leading to higher levels of fibrinogen, a pro-sticky blood component.

CONCLUSIONS: Pretreatment SII, albumin, and fibrinogen are independent prognostic factors in mCRPC patients treated with first-line docetaxel. Moreover, the combined use of SII, albumin, and fibrinogen levels may help us to identify the high-risk populations for treatment decisions.

"Inflammation. [3] SedRate, Fibrinogen, IL-6, TNFalpha." Elevated fibrinogen is a sign of inflammation & can be brought into the normal range, IMO.}

Other important biomarkers for CVD risk include: - LDL-P or ApoB - homocysteine - fibrinogen - Lp-pla2 or PLAC test; - hb-A1C - average blood glucose over last 3 months; - ALT - proxy for liver fat - Uric acid - proxy for sugar in the diet Good luck to all. P.S.

A new radiotracer focused on fibrinogen activation protein is being tested. . 68Ga-FAPI PET/CT seems to focus on fibrinogen in tumors and could possibly have chemo attached as a therapeutic application.

Low concentrations of recombinant gingipain R1 were also added to purified fluorescent fibrinogen.

ACTIV,CLAUSS FIBRINOGEN 237 (175-425 mg/dL) FSH <0.7 L (1.6-8.0 mIU/mL) LH <0.2 L (1.5-9.3 mIU/mL) THYROID PEROXIDASE AB <1 <9 IU/mL THYROGLOBULIN ANTIBODIES <1 < OR = 1 IU/mL CERULOPLASMIN 31 (18-36 mg/dL) VITAMIN C 0.7 (0.2-2.1 mg/dL) TNF-ALPHA,HIGHLY SENSITIVE 0.54 L (0.56-1.40 pg/mL) ESTRADIOL,

DVVRT last week was 1.31 DVVRT three months ago 1.33 Eight months ago 1.22 High ESR 60-70 Fibrinogen 4.3 (normal<4) History of TIA, possible stroke? Miscarriage X 1 at 11 weeks General feeling of heaviness/ache in legs after long haul flights --relieved by couple of days of Aspirin 300mg daily.

Fibrinogen circulates in the blood in readiness for clot formation. It requires the release of the enzyme thrombin for it to be converted into the fibrin strands that form a clot. Fibrinogen above the normal range is associated with inflammation.

She gave me copies of my blood results, and I did notice my prothrombin time is a bit low -11.5 (ref range 12-15) and my fibrinogen is a bit high-4.8 (ref range 2.0-4.5). She didn’t comment on it though. Anyway! That’s all for now.

Monitor your fibrinogen and homocysteine values in your blood tests regularly which measure blood platelet aggregation.

." *** Other old posts: "Inflammation. [2] Albumin & C-Reactive Protein [CRP]" [5] "Inflammation. [3] SedRate, Fibrinogen, IL-6, TNFalpha." [6] "Inflammation. [4] How to Change the Numbers" [7] -Patrick [1] https://www.ncbi.nlm.nih.gov/pubmed/30408799 [2] https://healthunlocked.com/advanced-prostate-cancer