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How prostate cancer transforms into aggressive NEPC following treatment with anti-androgen therapy.
This could be a game changer as it could stop PCa from progressing. Science is going to save us. The development of effective anti-androgen therapies for prostate cancer is a major scientific advance. However, some men who receive these targeted treatments are more likely to develop a deadly treatment-resistant
This could be a game changer as it could stop PCa from progressing. Science is going to save us. The development of effective anti-androgen therapies for prostate cancer is a major scientific advance. However, some men who receive these targeted treatments are more likely to develop a deadly treatment-resistant
Scout4answers
in
Advanced Prostate Cancer
8 months ago
I’m confused
So I posted before last year as had been having chest pain and pain in my left shoulder and arm which woke me from sleep on several occasions. I was referred to chest pain clinic at local hospital and tests and scans has revealed a considerable blockage in LAD. I went for angioplasty and they concluded
So I posted before last year as had been having chest pain and pain in my left shoulder and arm which woke me from sleep on several occasions. I was referred to chest pain clinic at local hospital and tests and scans has revealed a considerable blockage in LAD. I went for angioplasty and they concluded
sickandsore
in
British Heart Foundation
1 year ago
Does Anyone Feel?
I am wondering if its possible to feel as well on thyroid replacement as I did pre hypothyroid. Just for background looking back 4 years ago I felt really fit and healthy,had plenty of energy, was going to the gym. Then the pandemic hit and my gym closed down and went bust. In June 2020 I finally started
I am wondering if its possible to feel as well on thyroid replacement as I did pre hypothyroid. Just for background looking back 4 years ago I felt really fit and healthy,had plenty of energy, was going to the gym. Then the pandemic hit and my gym closed down and went bust. In June 2020 I finally started
Sparklingsunshine
in
Thyroid UK
1 year ago
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Hip Replacement
Has anyone had hip replacement surgery with a pacemaker. I have already had a hip replaced but that was before being diagnosed with Heart Failure and having a pacemaker. Just wondered if it is possible as I was told I would probably need the other hip replaced at some point. I have just started having
Has anyone had hip replacement surgery with a pacemaker. I have already had a hip replaced but that was before being diagnosed with Heart Failure and having a pacemaker. Just wondered if it is possible as I was told I would probably need the other hip replaced at some point. I have just started having
Lovedogs1
in
British Heart Foundation
10 months ago
red light therapy
been using red light therapy for 3 years - has there been double bind trials and if so what were results? Thanks
been using red light therapy for 3 years - has there been double bind trials and if so what were results? Thanks
Coling
in
Cure Parkinson's
8 months ago
grade IV chrondosis
Hello 1st post Just been diagnosed with grade 4 chrondosis which means knee replacement.I was gutted to hear this as I’m only 54 and play a bit of golf and try to keep active.All I hear is bad news stories regarding the replacement.Would be devastated if I can’t play the game I love again.Has anyone
Hello 1st post Just been diagnosed with grade 4 chrondosis which means knee replacement.I was gutted to hear this as I’m only 54 and play a bit of golf and try to keep active.All I hear is bad news stories regarding the replacement.Would be devastated if I can’t play the game I love again.Has anyone
2112mg
in
Arthritis Action
10 months ago
Next NoSilverBullet Zoom webinar on 13th of November: Interview of Dr Wayne Markman, CEO of Symbyx, on "Light therapy for Parkinson's".
I am delighted to announce that our next NoSilverBullet Zoom webinar will be taking place at 8.00pm London time on Monday the 13th of November. I will have the pleasure of interviewing Dr Wayne Markman, CEO of Symbyx, on "Light therapy for Parkinson's" Please use the Eventbrite link below to register
I am delighted to announce that our next NoSilverBullet Zoom webinar will be taking place at 8.00pm London time on Monday the 13th of November. I will have the pleasure of interviewing Dr Wayne Markman, CEO of Symbyx, on "Light therapy for Parkinson's" Please use the Eventbrite link below to register
Michel0220
in
Cure Parkinson's
8 months ago
Efficacy and safety of new‑generation BTKis (primarily acalabrutinib and zanubrutinib) in CLL/SLL: a systematic review and meta‑analysis
The meta-analysis of 20 studies on CLL/SLL patients treated with new-generation BTKis was based on papers selected from [i]"A comprehensive search on PubMed, Embase, Cochrane Library, and ClinicalTrials.gov. up to January 31, 2023".[/i] The full study title is
Efficacy and safety of new‑generation
The meta-analysis of 20 studies on CLL/SLL patients treated with new-generation BTKis was based on papers selected from [i]"A comprehensive search on PubMed, Embase, Cochrane Library, and ClinicalTrials.gov. up to January 31, 2023".[/i] The full study title is
Efficacy and safety of new‑generation
AussieNeil
Partner
in
CLL Support
8 months ago
Shalom316
my story begins with my left hip replacement over two years ago and virtually started having symptoms afterwards primarily a very slight tremor in my left hand . I tried chiropractors, Acupuncture, and eventually went to a neurologist and received a Parkinson‘s diagnosis. I am on C/L and have been researching
my story begins with my left hip replacement over two years ago and virtually started having symptoms afterwards primarily a very slight tremor in my left hand . I tried chiropractors, Acupuncture, and eventually went to a neurologist and received a Parkinson‘s diagnosis. I am on C/L and have been researching
Shililly
in
Cure Parkinson's
10 months ago
over 40 conception
I’m 41 going through my first cycle. I wanted to try and improve my chances of success due to my age. So have been taking coenzyme q10, regularly, as well as low dose melatonin, and omega 3 oils, folic acid and multivitamins. Also undergoing acupuncture and light therapy to improve egg quality. I’ve
I’m 41 going through my first cycle. I wanted to try and improve my chances of success due to my age. So have been taking coenzyme q10, regularly, as well as low dose melatonin, and omega 3 oils, folic acid and multivitamins. Also undergoing acupuncture and light therapy to improve egg quality. I’ve
Coffeeone
in
Fertility Network UK
8 months ago
Hashimotos
I have been diagnosed with Hashimotos quite recently, although I've been taking levothyroxine for over a year. I have been feeling exhausted, and have taken a lot of time off work this year as a result. These were my recent blood test results. My half sister also has Hashimotos, and she feels
I have been diagnosed with Hashimotos quite recently, although I've been taking levothyroxine for over a year. I have been feeling exhausted, and have taken a lot of time off work this year as a result. These were my recent blood test results. My half sister also has Hashimotos, and she feels
healthisimportant50
in
Women's Health
1 year ago
Old Guy Update
I was diagnosed in November 2020 with stage 4 Ductal adenocarcinoma of the prostate. I had EBRT and 24 months of ADT which was terminated in October of 2022. My PSA at that time was undetectable and my Testosterone was also undetectable. It’s now July 2024, and my PSA is 0.2 and my Testosterone is 10
I was diagnosed in November 2020 with stage 4 Ductal adenocarcinoma of the prostate. I had EBRT and 24 months of ADT which was terminated in October of 2022. My PSA at that time was undetectable and my Testosterone was also undetectable. It’s now July 2024, and my PSA is 0.2 and my Testosterone is 10
TottenhamMan
in
Advanced Prostate Cancer
7 hours ago
PSA at 0.285
I had my RP last January but the cancers had sneaked out to my lymph node already (no other met) so my PSA was always detectable. I started hormonal therapy last April and my PSA went down right away. It had been that way till this week ( PSA was up and down, the lowest was 0.02, usually was 0.05.).
I had my RP last January but the cancers had sneaked out to my lymph node already (no other met) so my PSA was always detectable. I started hormonal therapy last April and my PSA went down right away. It had been that way till this week ( PSA was up and down, the lowest was 0.02, usually was 0.05.).
Formosan
in
Advanced Prostate Cancer
1 day ago
Can I trust a second opinion?
It's not that I don't trust my MO, but he seems to be quite SOC, and doesn't offer options unless I bring them up. Which I have been doing. I even seem to have a reputation for having good questions. Which I am glad to hear, but frankly I don't feel I'm as well educated as all that 🙄. It could be that
It's not that I don't trust my MO, but he seems to be quite SOC, and doesn't offer options unless I bring them up. Which I have been doing. I even seem to have a reputation for having good questions. Which I am glad to hear, but frankly I don't feel I'm as well educated as all that 🙄. It could be that
Lewellen
in
Advanced Prostate Cancer
2 days ago
Hormone Therapy
.Hi..So my husband was diagnosed with Prostate Cancer via a routine check during a GPs appointment...It was 2020,and we went into lockdown for Covid not long after..He elected to have a Prostatectomy, but unfortunately his PSA never went to zero...Levels remained low, and he had a PET scan, which
.Hi..So my husband was diagnosed with Prostate Cancer via a routine check during a GPs appointment...It was 2020,and we went into lockdown for Covid not long after..He elected to have a Prostatectomy, but unfortunately his PSA never went to zero...Levels remained low, and he had a PET scan, which
debbiejayn
in
Advanced Prostate Cancer
3 days ago
The continuing saga of Scout and Coco, Not all change is welcome.
It is with sadness that I report that My "vacation" may come to an abrupt end . After cruising along with an Undetectable PSA for a little over 2+ years, my recent test results indicate a PSA of 0.03 and my Testosterone jumped from <7 to 13. The good news is my T is coming back but it looks like
It is with sadness that I report that My "vacation" may come to an abrupt end . After cruising along with an Undetectable PSA for a little over 2+ years, my recent test results indicate a PSA of 0.03 and my Testosterone jumped from <7 to 13. The good news is my T is coming back but it looks like
Scout4answers
in
Advanced Prostate Cancer
3 days ago
Are teeth affected by ADT or Xtandi?
after about 2 months of Lupron and Xtandi my teeth are tender and sore. Any correlation?
after about 2 months of Lupron and Xtandi my teeth are tender and sore. Any correlation?
CousinGrandpa
in
Prostate Cancer Network
4 days ago
Elgard v Lupron
I’ve experienced slowly increasing side effects over the past six to nine months. I passed it off to age and time on ADT, but I’ve recently discovered that I was switched from Lupron Depot to Eligard last November. Everything I read says the SEs should be the same. Has anyone else experienced the
I’ve experienced slowly increasing side effects over the past six to nine months. I passed it off to age and time on ADT, but I’ve recently discovered that I was switched from Lupron Depot to Eligard last November. Everything I read says the SEs should be the same. Has anyone else experienced the
Papa1
in
Advanced Prostate Cancer
4 days ago
PSA still undetectable and testosterone doubles to 1.6
Just an update as I yesterday was blood test day. I’m continuing with the Apalutamide monotherapy, still enjoying working full time and just back from an Italian lake holiday. So no movement on my PSA but interesting to see testosterone creeping up ( 11 months since my last Zoledex injection so 8
Just an update as I yesterday was blood test day. I’m continuing with the Apalutamide monotherapy, still enjoying working full time and just back from an Italian lake holiday. So no movement on my PSA but interesting to see testosterone creeping up ( 11 months since my last Zoledex injection so 8
Brysonal
in
Fight Prostate Cancer
4 days ago
Docetaxel
Anyone willing to share experiences with Docetaxel? Good, Bad, and Ugly. Any recommendations or advice to help with side effects etc. My husband is in year 7… He has been on the traditional SOC with ADT… Lupron, Firmagon, Nubequa, and lastly Zytiga. All have ceased working. His PSA has risen to
Anyone willing to share experiences with Docetaxel? Good, Bad, and Ugly. Any recommendations or advice to help with side effects etc. My husband is in year 7… He has been on the traditional SOC with ADT… Lupron, Firmagon, Nubequa, and lastly Zytiga. All have ceased working. His PSA has risen to
JolleySprings
in
Advanced Prostate Cancer
4 days ago
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