Are teeth affected by ADT or Xtandi?

[CousinGrandpa]

after about 2 months of Lupron and Xtandi my teeth are tender and sore. Any correlation?

[BubbaC]

I believe there is a direct correlation based on my personal experience. I've been on Orgovyx for about 28 months and over the course of that time three of my teeth cracked and needed serious dental work. I've also been on Prolia and that may have contributed as well.

Good luck!

[CousinGrandpa in reply to BubbaC]

ty

[Jpl506]

I had the same experience, teeth became sensitive and ached. MO denied there was a link but I thought it strange it hadn’t happened prior to or since ADT. I used a prescription fluoride toothpaste and rinse daily for a few weeks and it helped quite a bit.

[Mascouche]

Though there was no link when 3 of my teeth chipped after about 15 months on ADT but after reading you guys, maybe there is a link. Teeth are basically bones, right? Maybe they lose some density too?

[Jaffa_2001]

I have had strange things going on in my mouth since starting ADT, so I am pleased some others are sharing their experiences here.

I have all my wisdom teeth apart from one that is partially through and has never caused me a lot of pain or been a problem in 20 years of it trying to fully erupt. Always keep it clean and have regular check-ups.

But 3 months into Lupron it has become a nightmare with a lot of pain and bleeding on and off. It settles for a while and then starts all over again. Plus I have tenderness sometimes in my upper gums and mouth.

Another thing I have noticed is a dryness inside my nose with occasional soreness there too. ADT has also depleted my white blood cell count so that I have got Neutropenia. I questioned my consultants about this and they confirmed it was a side effect of Lupron.

Their response "try and avoid anyone who is ill or unwell". Glad to see the NHS service here is as much in the dark about unlisted side effects of the medication/treatment they are advocating......

My ADT finished 4 weeks ago but I am still firmly entrenched in Lupron City, with the side effects to be honest worse rather than better, just hope they improve over time.

Research suggests anything from 3-6 months or even longer. Joy!

We plod on!

[dentaltwin]

ADT has a strong association with periodontal disease:

ncbi.nlm.nih.gov/pmc/articl...

It can also cause dry mouth, which favors development of caries.

[London441]

As with many of parts of the body, ADT is most unkind. Being especially fastidious about your oral hygiene is a must, even if no guarantee of protection. Plenty of exercise is critical also.

[conbio]

18 months of Lupron - no teeth issues

[j-o-h-n]

Many years on Lupron............many side effects........but my bite is worse than my bark.......

Good Luck, Good Health and Good Humor.

j-o-h-n

[CousinGrandpa in reply to j-o-h-n]

lol. Hope it continues

[j-o-h-n in reply to CousinGrandpa]

Thank you and may you be around for at least 5 more years past my current age. If so better change your UserID to OldCousinGrandpa.....

Good Luck, Good Health and Good Humor.

j-o-h-n