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declining psa
I’m 8 years post RP and my PSA has gradually been going up over the past 6 years. When it hit 0.1 I saw a radiation oncologist to discuss options. He said I had a biochemical recurrence but is happy to monitor things and would only consider recommending salvage radiation when I get closer to 0.2. However
I’m 8 years post RP and my PSA has gradually been going up over the past 6 years. When it hit 0.1 I saw a radiation oncologist to discuss options. He said I had a biochemical recurrence but is happy to monitor things and would only consider recommending salvage radiation when I get closer to 0.2. However
Fransella
in
Active Surveillance - Prostate Cancer
1 year ago
ADT + darolutamide + docetaxel (ARASENS trial) has anyone tried it?
Hi people! My first update since the diagnosis. After less than one month of regrouping and ADT only (decapeptyl - triptotrelin, which got my PSA from 70 to 15), my MO decided to do the ARASENS trial triplet (with my full approval, I was going to propose him this protocol). Has anyone tried it?
Hi people! My first update since the diagnosis. After less than one month of regrouping and ADT only (decapeptyl - triptotrelin, which got my PSA from 70 to 15), my MO decided to do the ARASENS trial triplet (with my full approval, I was going to propose him this protocol). Has anyone tried it?
Maxone73
in
Advanced Prostate Cancer
1 year ago
PSA Tests
Every 6 months, I get a standard PSA test (following surgery and radiation four years ago) and it is "undetectable". Under what conditions is an ultrasensitive PSA test useful?
Every 6 months, I get a standard PSA test (following surgery and radiation four years ago) and it is "undetectable". Under what conditions is an ultrasensitive PSA test useful?
Polaris1
in
Advanced Prostate Cancer
1 year ago
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"Pluvicto"
Has anyone doing the six stages of Pluvicto, or finished the set, found that it has dropped their PSA ?? I will be taking my third infusion but have not done any blood work yet for PSA. Curious............................
Has anyone doing the six stages of Pluvicto, or finished the set, found that it has dropped their PSA ?? I will be taking my third infusion but have not done any blood work yet for PSA. Curious............................
Kian28
in
Advanced Prostate Cancer
1 year ago
from undetectable to 0.02
I have been undetectable for 3.25 years and today it came back at 0.02. My bio is up to date. We ran the test at the exact same lab as always and in 2 days I am flying back to my Sarasota home from Milwaukee and was wondering which lab is recommended for 2 digit accuracy? I know Labcorp only does 1
I have been undetectable for 3.25 years and today it came back at 0.02. My bio is up to date. We ran the test at the exact same lab as always and in 2 days I am flying back to my Sarasota home from Milwaukee and was wondering which lab is recommended for 2 digit accuracy? I know Labcorp only does 1
Peppertree602
in
Advanced Prostate Cancer
1 year ago
Aspirin trials
I have recently finished hormone therapy, last 3 monthly injection April 2023. Good result so far with PSA at <0.01. Met with my Oncologist today and he said there were trials using aspirin as a potential drug to reduce potential recurrence. Has anyone come across this and, even though the results
I have recently finished hormone therapy, last 3 monthly injection April 2023. Good result so far with PSA at <0.01. Met with my Oncologist today and he said there were trials using aspirin as a potential drug to reduce potential recurrence. Has anyone come across this and, even though the results
Runner1957
in
Prostate Cancer Network
1 year ago
Abiraterone SE when added to Lupron?
I am a PSA =2, low volume, oligometastic HSPC. I got my first Lupron shot 4 weeks ago. I started to get a couple hot flashes per day in the last week from the Lupron and of course I expect fatigue to kick in over the next six weeks. What additional side effects might I expect by adding the abiraterone
I am a PSA =2, low volume, oligometastic HSPC. I got my first Lupron shot 4 weeks ago. I started to get a couple hot flashes per day in the last week from the Lupron and of course I expect fatigue to kick in over the next six weeks. What additional side effects might I expect by adding the abiraterone
jackwfrench
in
Advanced Prostate Cancer
1 year ago
Finished 8 Rounds of Docetaxel
Hi Fellow Warriors, Four weeks ago I finished up 8 rounds of Docetaxel. This year has been a medical shit show: 2 UTIs, pneumonia, Covid, sepsis, sinus infection which became chronic sinusitis, numerous falls with the last fall resulting in a dislocated hip. The good news! Before starting Docetaxel
Hi Fellow Warriors, Four weeks ago I finished up 8 rounds of Docetaxel. This year has been a medical shit show: 2 UTIs, pneumonia, Covid, sepsis, sinus infection which became chronic sinusitis, numerous falls with the last fall resulting in a dislocated hip. The good news! Before starting Docetaxel
MJCA
in
Advanced Prostate Cancer
1 year ago
Sounds like a plan, start 10/2.
IMPRESSION: Seventy-four-year-old male with unfavorable intermediate risk prostatic adenocarcinoma, PSA 6.8 ng/mL and Gleason 7 (4+3). RECOMMENDATION: He wishes to proceed with definitive EBRT to the prostate & SV. Total dose will be 81 Gy/45 fractions on TrueBeam using RapidArc VMAT with daily CBCT
IMPRESSION: Seventy-four-year-old male with unfavorable intermediate risk prostatic adenocarcinoma, PSA 6.8 ng/mL and Gleason 7 (4+3). RECOMMENDATION: He wishes to proceed with definitive EBRT to the prostate & SV. Total dose will be 81 Gy/45 fractions on TrueBeam using RapidArc VMAT with daily CBCT
Hobie14
in
Prostate Cancer Network
1 year ago
Tumor Mutation Burden
Last genetic test has shwon TMB 10.86 and the orevious one (in March, 2023) showed the value of 8.68. Will increased TMB require the addition of PARP inhibitors to my current therapy consisting of Loupron and Abiraterone? Anyone has similar experience? My history can be seen under bio. Just to add that
Last genetic test has shwon TMB 10.86 and the orevious one (in March, 2023) showed the value of 8.68. Will increased TMB require the addition of PARP inhibitors to my current therapy consisting of Loupron and Abiraterone? Anyone has similar experience? My history can be seen under bio. Just to add that
venecia1983
in
Advanced Prostate Cancer
1 year ago
ART NIH Predicting the Outcome of Salvage Radiation Therapy for Recurrent Prostate Cancer After Radical Prostatectomy
Summary: Patients in this audience have had both radical prostatectomies (RP) and salvage radiation treatment (sRT) and want to know their chances of having recurrent prostate cancer. This study developed a predictive model called a nomogram that predicts the 6-year progression-free probability (PFP
Summary: Patients in this audience have had both radical prostatectomies (RP) and salvage radiation treatment (sRT) and want to know their chances of having recurrent prostate cancer. This study developed a predictive model called a nomogram that predicts the 6-year progression-free probability (PFP
RMontana
in
Active Surveillance - Prostate Cancer
1 year ago
Enzalutamide (Xtandi): Start at half standard dose to extend efficacy time span?
Good Morning AllI was disgnosed 6 years ago with oligometastic prostate cancer Gleeson 8, PSA 22. Since January 2018 I have been on ADT, had docetaxel chemo in April 2018, radiotherapy to the prostate, seminal vessel and pelvis in November 2018 when PSA dropped to <0.1. PSMA PET CT scan in March 2019
Good Morning AllI was disgnosed 6 years ago with oligometastic prostate cancer Gleeson 8, PSA 22. Since January 2018 I have been on ADT, had docetaxel chemo in April 2018, radiotherapy to the prostate, seminal vessel and pelvis in November 2018 when PSA dropped to <0.1. PSMA PET CT scan in March 2019
KGU1
in
Advanced Prostate Cancer
1 year ago
testosterone finally moving up after Treatment.
April of 2018 I was diagnosed with stage 111 PC with a tumor against my rectum. Finally after 19 months of lupron and zytiga and 40 rounds of radiation my testosterone has hit 325. I do 3 month testing and it has held for 6 months. I can feel the difference and am not only doing more but my weight is
April of 2018 I was diagnosed with stage 111 PC with a tumor against my rectum. Finally after 19 months of lupron and zytiga and 40 rounds of radiation my testosterone has hit 325. I do 3 month testing and it has held for 6 months. I can feel the difference and am not only doing more but my weight is
lowT163
in
Advanced Prostate Cancer
1 year ago
How to lower PSA
PSA was high. If it doesn’t come down they want to do a biopsy. Any tips on how to lower it?
PSA was high. If it doesn’t come down they want to do a biopsy. Any tips on how to lower it?
Archer79
in
Osteoporosis Support
1 year ago
When Should I Be Concerned About My PSA
Hello, all. In early 2020, I was treated with a combination of six months of bicalutamide 50mg, and HDR-BT. Because of COVID-19, I had to wait a year before I had my 1st. PSA after treatment. I've had a few bounces and even though I was told PSA bounces were to be expected, it's been about three years
Hello, all. In early 2020, I was treated with a combination of six months of bicalutamide 50mg, and HDR-BT. Because of COVID-19, I had to wait a year before I had my 1st. PSA after treatment. I've had a few bounces and even though I was told PSA bounces were to be expected, it's been about three years
Arthro92
in
Prostate Cancer Network
1 year ago
Now what?
My husband was DX April 2021 MPc, Stage IV, PSA 335, BRACA2. Lupron, Erleada, Provenge, Lynparza (still on), Zytiga/Pred (still on). PSA rose from 2.64 Feb 2023 to 44 Sept 2023. Biggest jumps on the last three months, 10 to 44. He is approved for 177lu, but there are a lot of unsuccessful stories
My husband was DX April 2021 MPc, Stage IV, PSA 335, BRACA2. Lupron, Erleada, Provenge, Lynparza (still on), Zytiga/Pred (still on). PSA rose from 2.64 Feb 2023 to 44 Sept 2023. Biggest jumps on the last three months, 10 to 44. He is approved for 177lu, but there are a lot of unsuccessful stories
Hidden
in
Advanced Prostate Cancer
1 year ago
PSA still low but cancer progressing
I've been on ADT plus Xtandi for about a year (see my profile) and my PSA has steadily reduced and stayed low. However, my latest CT scan shows that the tumours on my bones and lymph nodes are increasing in size and there are now a few small lesions appearing in my liver for the first time. Not the news
I've been on ADT plus Xtandi for about a year (see my profile) and my PSA has steadily reduced and stayed low. However, my latest CT scan shows that the tumours on my bones and lymph nodes are increasing in size and there are now a few small lesions appearing in my liver for the first time. Not the news
Benkaymel
in
Advanced Prostate Cancer
1 year ago
Am I candidate for AS?
66 year old, Dx January 2022 PSA peak 5.76 [u]Biopsy 3/15/22[/u] 3 of 14 cores PCa 1 of 4 cores, 4+3, 80% Gr 4, <5% of tissue, left posterior 2 of 2 cores, 3+4, 20% Gr 4, 20% of tissue, left mid Decipher .34, cut off for low aggression is .45 NanoKnife June 6, 2022 PSA nadir 1.21 [u]Biopsy 5/16
66 year old, Dx January 2022 PSA peak 5.76 [u]Biopsy 3/15/22[/u] 3 of 14 cores PCa 1 of 4 cores, 4+3, 80% Gr 4, <5% of tissue, left posterior 2 of 2 cores, 3+4, 20% Gr 4, 20% of tissue, left mid Decipher .34, cut off for low aggression is .45 NanoKnife June 6, 2022 PSA nadir 1.21 [u]Biopsy 5/16
Piano777
in
Prostate Cancer Network
1 year ago
Whole pelvic radiation after testicular cancer?
My husband is 63, dx Oct/2022 with PSA of ~11 and all twelve cores positive with GL 8 and mostly 9’s (4+5). He had SVI, PNI, and probable ECE, but PSMA PET showed no spread. He’s being treated at UCHealth/Denver CO at their urologic cancer center. His treatment consisted of 39 radiation sessions +
My husband is 63, dx Oct/2022 with PSA of ~11 and all twelve cores positive with GL 8 and mostly 9’s (4+5). He had SVI, PNI, and probable ECE, but PSMA PET showed no spread. He’s being treated at UCHealth/Denver CO at their urologic cancer center. His treatment consisted of 39 radiation sessions +
Adendino
in
Advanced Prostate Cancer
1 year ago
Just feeling down
Hi Group, To get to it, my PSA recently jumped back up about 60%. It’s now over 1600 after lowering to around 1000. . I’m just learning to manage radiation side effects - to the extent I can - and trying to move back into some “normal” or at least semi-stable state. Then last night my partner admitted
Hi Group, To get to it, my PSA recently jumped back up about 60%. It’s now over 1600 after lowering to around 1000. . I’m just learning to manage radiation side effects - to the extent I can - and trying to move back into some “normal” or at least semi-stable state. Then last night my partner admitted
Arel8
in
Advanced Prostate Cancer
1 year ago
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