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Levodopa-Induced Euphoria and Addictions in Parkinson’s. It's of concern for people with neuropsychiatric fluctuations between ON and OFF.
I'm referencing a 2017 research article. Some people have more significant neuropsychiatric fluctuations between ON and OFF levodopa drug treatment states. These people seem to be more at risk for triggered addictive behavior and drug abuse. The conclusion of the abstract is "The psychostimulant effects
I'm referencing a 2017 research article. Some people have more significant neuropsychiatric fluctuations between ON and OFF levodopa drug treatment states. These people seem to be more at risk for triggered addictive behavior and drug abuse. The conclusion of the abstract is "The psychostimulant effects
ElliotGreen
in
Cure Parkinson's
5 years ago
Interesting thought Dr!
Hi all. I hope that this post finds you all as well as can be expected😊. I don’t write too much these days, not because I’m too bad or anything but I just don’t have as many thoughts as I used to have about the disease. I exercised, juiced, fasted, red light hatted and I still have it unfortunately!
Hi all. I hope that this post finds you all as well as can be expected😊. I don’t write too much these days, not because I’m too bad or anything but I just don’t have as many thoughts as I used to have about the disease. I exercised, juiced, fasted, red light hatted and I still have it unfortunately!
jeeves19
in
Cure Parkinson's
5 years ago
How is it related to dopamine (and Levodopa)?
Top News in Neurology Researchers discover new piece of the puzzle for Parkinson disease MedicalXpress Breaking News-and-Events | January 30, 2020 https://www.mdlinx.com/neurology/top-medical-news/article/2020/01/30/7604039?uic=ZZ9D8B8B9F0D494D92A02690CB41758420&utm_source=Sailthru&utm_medium=email&utm_campaign
Top News in Neurology Researchers discover new piece of the puzzle for Parkinson disease MedicalXpress Breaking News-and-Events | January 30, 2020 https://www.mdlinx.com/neurology/top-medical-news/article/2020/01/30/7604039?uic=ZZ9D8B8B9F0D494D92A02690CB41758420&utm_source=Sailthru&utm_medium=email&utm_campaign
stepan13
in
Cure Parkinson's
5 years ago
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8 Year Anniversary 😀
Jan 19 marked the occasion of quitting cigarettes for 8 years. The day passed, and it didn't even register that it was my anniversary since I rarely think of cigarettes any more. Sometimes, if I do think of cigarettes, exercise will take away any wish to smoke: I guess it's the dopamine hit of exercise
Jan 19 marked the occasion of quitting cigarettes for 8 years. The day passed, and it didn't even register that it was my anniversary since I rarely think of cigarettes any more. Sometimes, if I do think of cigarettes, exercise will take away any wish to smoke: I guess it's the dopamine hit of exercise
nonico
7 Years Smoke Free
in
No Smoking Day
5 years ago
Ohiohhealth
https://www.youtube.com/watch?v=ChtUlpfkPZA&list=PLrLDtjEaWrDuuwlsakceQHQ-O1IVktGou May be old news but these 12 lectures discuss much of what I've read on this site. #12 talks about sinemet and the dopamine agonists.
https://www.youtube.com/watch?v=ChtUlpfkPZA&list=PLrLDtjEaWrDuuwlsakceQHQ-O1IVktGou May be old news but these 12 lectures discuss much of what I've read on this site. #12 talks about sinemet and the dopamine agonists.
kaypeeoh
in
Cure Parkinson's
5 years ago
Caution with drugs
Just a caution to everyone. My husband was recently in the hospital with rapid atrial fibrillation. They used two drugs on him that apparently should not be used for Parkinson’s one was a calcium channel blocker the other was amiodarone commonly used for heart arrhythmia these drugs block dopamine
Just a caution to everyone. My husband was recently in the hospital with rapid atrial fibrillation. They used two drugs on him that apparently should not be used for Parkinson’s one was a calcium channel blocker the other was amiodarone commonly used for heart arrhythmia these drugs block dopamine
bubee
in
Cure Parkinson's
5 years ago
iPSC modeling of young-onset Parkinson’s disease reveals a molecular signature of disease and novel therapeutic candidates
Young-onset Parkinson’s disease (YOPD), defined by onset at <50 years, accounts for approximately 10% of all Parkinson’s disease cases and, while some cases are associated with known genetic mutations, most are not. Here induced pluripotent stem cells were generated from control individuals and from
Young-onset Parkinson’s disease (YOPD), defined by onset at <50 years, accounts for approximately 10% of all Parkinson’s disease cases and, while some cases are associated with known genetic mutations, most are not. Here induced pluripotent stem cells were generated from control individuals and from
Farooqji
in
Cure Parkinson's
5 years ago
Circadian Rhythms
I'm currently on holiday in a sunny country. I dreaded coming because of my insomnia and rls and the thought of pacing up and down all night in a strange room filled me with dread and I almost cancelled at the last minute but my daughter insisted I go. For the first two I only slept by taking zopiclone
I'm currently on holiday in a sunny country. I dreaded coming because of my insomnia and rls and the thought of pacing up and down all night in a strange room filled me with dread and I almost cancelled at the last minute but my daughter insisted I go. For the first two I only slept by taking zopiclone
Hoochybaby
in
Restless Legs Syndrome
5 years ago
Possible causes of Ataxia
🙂 This is a ‘long read’ and may be difficult to interpret, but never the less it’s interesting. What processes can cause ataxia? The pathophysiology of cerebellar ataxias is as diverse as the various neurological and systemic diseases affecting the cerebellum. Broadly classifying ataxias into genetic
🙂 This is a ‘long read’ and may be difficult to interpret, but never the less it’s interesting. What processes can cause ataxia? The pathophysiology of cerebellar ataxias is as diverse as the various neurological and systemic diseases affecting the cerebellum. Broadly classifying ataxias into genetic
wobblybee
in
Ataxia UK
5 years ago
Need help please, sense of smell, response to C/l, and sleep issue POLL
I’m confused. I’ve been clinically diagnosed with Parkinson’s with a DatScan performed in Dec. 2018. 4 months prior to my DatScan raised my antidepressant to max levels from the lowest level I had been taking for about 6 years prior. My symptoms got worse overnight. Looking back, my symptoms started
I’m confused. I’ve been clinically diagnosed with Parkinson’s with a DatScan performed in Dec. 2018. 4 months prior to my DatScan raised my antidepressant to max levels from the lowest level I had been taking for about 6 years prior. My symptoms got worse overnight. Looking back, my symptoms started
38yroldmale
in
Cure Parkinson's
5 years ago
Hyperbaric Oxygen Therapy
Hyperbaric Oxygen Therapy has been discussed on this forum before, but I still find it intriguing. I watched a news story today regarding a former National Football League player (Packers great Dave Robinson) who underwent hyperbaric oxygen therapy to treat brain damage from concussions. Apparently
Hyperbaric Oxygen Therapy has been discussed on this forum before, but I still find it intriguing. I watched a news story today regarding a former National Football League player (Packers great Dave Robinson) who underwent hyperbaric oxygen therapy to treat brain damage from concussions. Apparently
jimcaster
in
Cure Parkinson's
5 years ago
New ray of hope for people living with Parkinson’s disease
https://www.thehealthsite.com/news/new-ray-of-hope-for-people-living-with-parkinsons-disease-723790/ Parkinson's disease affects millions across the world. A non-invasive technique may soon come to the rescue. A non-invasive technique which could be used later to treat Parkinson’s disease has been discovered
https://www.thehealthsite.com/news/new-ray-of-hope-for-people-living-with-parkinsons-disease-723790/ Parkinson's disease affects millions across the world. A non-invasive technique may soon come to the rescue. A non-invasive technique which could be used later to treat Parkinson’s disease has been discovered
John_morris71
in
Cure Parkinson's
5 years ago
Fighting ADTs side effects: Astenia, ginaecomastia, ostheoporosis, depression,...
Hello guys... Opinion on some meds please. This is me: 49. PSA 13 march 2019 , mHSPC oligometastatic per PSMA in prostate G7, locoregional nodes and 1 rib , I started ADT 3 month shot in march 2019. In summer I had developed nefrolitiasis, ginaecomastia, huge fatigue, insomnia and osteoporosis -2.5 PSA
Hello guys... Opinion on some meds please. This is me: 49. PSA 13 march 2019 , mHSPC oligometastatic per PSMA in prostate G7, locoregional nodes and 1 rib , I started ADT 3 month shot in march 2019. In summer I had developed nefrolitiasis, ginaecomastia, huge fatigue, insomnia and osteoporosis -2.5 PSA
Manilo
in
Advanced Prostate Cancer
5 years ago
I have dopamine issues Willis ekobom disease
I have rls had it forever its nothing new also have aspergers syndrome don't know if theres a connection, been taking ropinirole for a while starting to make me feel poorly changing to pramipexole they said change straight away but I cant the pramipexole is so low of dose cant cope with the legs , so
I have rls had it forever its nothing new also have aspergers syndrome don't know if theres a connection, been taking ropinirole for a while starting to make me feel poorly changing to pramipexole they said change straight away but I cant the pramipexole is so low of dose cant cope with the legs , so
Jasongreg
in
Restless Legs Syndrome
5 years ago
Basic dopamine question
I'm hoping one ye clever cats can help me understand something. Dopamine is made in the following way: Phenylalanine -> tyrosine -> l-dopa -> dopamine Who is responsible for doing this? Is it the dopamine neuron job or is it just the neuron's job to deliver the dopamine across the brain once it's produced
I'm hoping one ye clever cats can help me understand something. Dopamine is made in the following way: Phenylalanine -> tyrosine -> l-dopa -> dopamine Who is responsible for doing this? Is it the dopamine neuron job or is it just the neuron's job to deliver the dopamine across the brain once it's produced
Parkinsonjisung
in
Cure Parkinson's
5 years ago
Effects of Coming off Rotigitone (Neupro Patches
Can anyone share with me experience of coming off Rotigitone please. I've been on 2mg patches for around 15 years but they had started not to be as effective as they had been. Having read about augmentation on here I didn't want to increase the dose. I started on Gaberpentine just before Christmas
Can anyone share with me experience of coming off Rotigitone please. I've been on 2mg patches for around 15 years but they had started not to be as effective as they had been. Having read about augmentation on here I didn't want to increase the dose. I started on Gaberpentine just before Christmas
omtenaj
in
Restless Legs Syndrome
5 years ago
Has your PD symptoms changed since taking a MAO-B inhibitor (see list of meds below)?
The article, "Waking up dormant dopaminergic neurons to reverse Parkinson's disease" claims a MAO-B inhibitor could wake up dopamine producing neurons. This question is to see how MAO-B inhibitors have affected people here. List of MAO-B inhibitors: Eldepryl® (selegiline hydrochloride) Carbex® (selegiline
The article, "Waking up dormant dopaminergic neurons to reverse Parkinson's disease" claims a MAO-B inhibitor could wake up dopamine producing neurons. This question is to see how MAO-B inhibitors have affected people here. List of MAO-B inhibitors: Eldepryl® (selegiline hydrochloride) Carbex® (selegiline
pvw2
in
Cure Parkinson's
5 years ago
Waking up dormant dopaminergic neurons to reverse Parkinson's disease
Led by Dr. C. Justin Lee along with Dr. Hoon Ryu and Dr. Sang Ryong Jeon, researchers at the Center for Cognition and Sociality within the Institute for Basic Science (IBS), Korea Institute of Science and Technology (KIST), and Asan Medical Center (AMC) have discovered a new mechanism for PD pathology
Led by Dr. C. Justin Lee along with Dr. Hoon Ryu and Dr. Sang Ryong Jeon, researchers at the Center for Cognition and Sociality within the Institute for Basic Science (IBS), Korea Institute of Science and Technology (KIST), and Asan Medical Center (AMC) have discovered a new mechanism for PD pathology
Farooqji
in
Cure Parkinson's
5 years ago
Neurologist Examination
Neurologist exam this morning, 1/9/2020, review: I was diagnosed 2012 Bedtime C/L 50-200 ER: Because it is ER, I take with or w/o food. 5 x day C/L 25 - 100 IR: 6:30, 9:30, 12:30, 3:30, 6:30 B1 (8 am 2g, and 12:30 pm 2g) vitamin B1 as thiamine HCL. 500mg, easy swallow capsules Assessment and Plan
Neurologist exam this morning, 1/9/2020, review: I was diagnosed 2012 Bedtime C/L 50-200 ER: Because it is ER, I take with or w/o food. 5 x day C/L 25 - 100 IR: 6:30, 9:30, 12:30, 3:30, 6:30 B1 (8 am 2g, and 12:30 pm 2g) vitamin B1 as thiamine HCL. 500mg, easy swallow capsules Assessment and Plan
Hidden
in
Cure Parkinson's
5 years ago
Medicine
My neurologist has prescribed Prozac and Seconal for my PD. I read where these two drugs cause decrease in Dopamine? Has anyone else heard or read about this?
My neurologist has prescribed Prozac and Seconal for my PD. I read where these two drugs cause decrease in Dopamine? Has anyone else heard or read about this?
Foncie
in
Cure Parkinson's
5 years ago
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